トランスオミクス医学研究センター

研究成果

2008
71 引用 (Scopus)
2007

Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia

Deng, X., Shibata, H., Takeuchi, N., Rachi, S., Sakai, M., Ninomiya, H., Iwata, N., Ozaki, N. & Fukumaki, Y., 4 5 2007, : : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 144, 3, p. 271-278 8 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling

Dacwag, C. S., Ohkawa, Y., Pal, S., Sif, S. & Imbalzano, A. N., 1 1 2007, : : Molecular and cellular biology. 27, 1, p. 384-394 11 p.

研究成果: ジャーナルへの寄稿記事

109 引用 (Scopus)
2006

Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice

Niki, S., Oshikawa, K., Mouri, Y., Hirota, F., Matsushima, A., Yano, M., Han, H., Bando, Y., Izumi, K., Matsumoto, M., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 5 1 2006, : : Journal of Clinical Investigation. 116, 5, p. 1292-1301 10 p.

研究成果: ジャーナルへの寄稿記事

79 引用 (Scopus)

Analysis of CDMA systems that are characterized by eigenvalue spectrum

Takeda, K., Uda, S. & Kabashima, Y., 2006, : : Europhysics Letters. 76, p. 1193-1199

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

A novel crude oil emulsifier excreted in the culture supernatant of a marine bacterium, Myroides sp. strain SM1

Maneerat, S., Bamba, T., Harada, K., Kobayashi, A., Yamada, H. & Kawai, F., 3 1 2006, : : Applied Microbiology and Biotechnology. 70, 2, p. 254-259 6 p.

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)

Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia

Shibata, H., Aramaki, T., Sakai, M., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. & Fukumaki, Y., 1 30 2006, : : Psychiatry research. 141, 1, p. 39-51 13 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Chromatin remodelling in mammalian differentiation: Lessons from ATP-dependent remodellers

De La Serna, I. L., Ohkawa, Y. & Imbalzano, A. N., 6 1 2006, : : Nature Reviews Genetics. 7, 6, p. 461-473 13 p.

研究成果: ジャーナルへの寄稿評論記事

284 引用 (Scopus)

Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1

Ohkawa, Y., Marfella, C. G. A. & Imbalzano, A. N., 2 8 2006, : : EMBO Journal. 25, 3, p. 490-501 12 p.

研究成果: ジャーナルへの寄稿記事

96 引用 (Scopus)

The contactin 4 gene locus at 3p26 is a candidate gene of SCA16

Miura, S., Shibata, H., Furuya, H., Ohyagi, Y., Osoegawa, M., Miyoshi, Y., Matsunaga, H., Shibata, A., Matsumoto, N., Iwaki, A., Taniwaki, T., Kikuchi, H., Kira, J. & Fukumaki, Y., 10 1 2006, : : Neurology. 67, 7, p. 1236-1241 6 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)
2005

Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Lee, H. J., Song, J. Y., Kim, J. W., Jin, S. Y., Hong, M. S., Park, J. K., Chung, J. H., Shibata, H. & Fukumaki, Y., 8 31 2005, : : Behavioral and Brain Functions. 1, 15.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p

Arinami, T., Ohtsuki, T., Ishiguro, H., Ujike, H., Tanaka, Y., Morita, Y., Mineta, M., Takeichi, M., Yamada, S., Imamura, A., Ohara, K., Shibuya, H., Ohara, K., Suzuki, Y., Muratake, T., Kaneko, N., Someya, T., Inada, T., Yoshikawa, T., Toyota, T. および32人, Yamada, K., Kojima, T., Takahashi, S., Osamu, O., Shinkai, T., Nakamura, M., Fukuzako, H., Hashiguchi, T., Niwa, S. I., Ueno, T., Tachikawa, H., Hori, T., Asada, T., Nanko, S., Kunugi, H., Hashimoto, R., Ozaki, N., Iwata, N., Harano, M., Arai, H., Ohnuma, T., Kusumi, I., Koyama, T., Yoneda, H., Fukumaki, Y., Shibata, H., Kaneko, S., Higuchi, H., Yasui-Furukori, N., Numachi, Y., Itokawa, M. & Okazaki, Y., 12 2005, : : American journal of human genetics. 77, 6, p. 937-944 8 p.

研究成果: ジャーナルへの寄稿記事

71 引用 (Scopus)

Identification of single-nucleotide polymorphisms in the human N-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia

Makino, C., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 9 1 2005, : : Psychiatric Genetics. 15, 3, p. 215-221 7 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Large-scale analysis of the human ubiquitin-related proteome

Matsumoto, M., Hatakeyama, S., Oyamada, K., Oda, Y., Nishimura, T. & Nakayama, K. I., 11 1 2005, : : Proteomics. 5, 16, p. 4145-4151 7 p.

研究成果: ジャーナルへの寄稿記事

145 引用 (Scopus)

Mammalian E4 is required for cardiac development and maintenance of the nervous system

Kaneko-Oshikawa, C., Nakagawa, T., Yamada, M., Yoshikawa, H., Matsumoto, M., Yada, M., Hatakeyama, S., Nakayama, K. & Nakayama, K. I., 12 1 2005, : : Molecular and cellular biology. 25, 24, p. 10953-10964 12 p.

研究成果: ジャーナルへの寄稿記事

44 引用 (Scopus)

Mapping of ubiquitination sites on target proteins

Hatakeyama, S., Matsumoto, M. & Nakayama, K., 1 1 2005, : : Methods in enzymology. 399, p. 277-286 10 p., 19.

研究成果: ジャーナルへの寄稿評論記事

8 引用 (Scopus)
50 引用 (Scopus)

MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex

De La Serna, I. L., Ohkawa, Y., Berkes, C. A., Bergstrom, D. A., Dacwag, C. S., Tapscott, S. J. & Imbalzano, A. N., 5 1 2005, : : Molecular and cellular biology. 25, 10, p. 3997-4009 13 p.

研究成果: ジャーナルへの寄稿記事

193 引用 (Scopus)

Purification, primary structures and evolution of coagulant proteases from Deinagkistrodon actus venom

Nikandrov, N. N., Deshimaru, M., Tani, A., Chijiwa, T., Shibata, H., Chang, C. C., Fukumaki, Y., Ito, T. & Ohno, M., 12 15 2005, : : Toxicon. 46, 8, p. 907-917 11 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Statistical mechanical development of a sparse Bayesian classifier

Uda, S. & Kabashima, Y., 2005, : : Journal of the Physical Society of Japan. 74, p. 2233-2242

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)
2004

A BP-Based Algorithm for Performing Bayesian Inference in Large Perceptron-Type Networks

Kabashima, Y. & Uda, S., 2004, International Conference on Algorithmic Learning Theory. p. 479-493

研究成果: 著書/レポートタイプへの貢献会議での発言

7 引用 (Scopus)

Association study of polymorphisms in the excitatory amino acid transporter 2 gene (SLC1A2) with schizophrenia

Deng, X., Shibata, H., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. & Fukumaki, Y., 8 6 2004, : : BMC Psychiatry. 4, 21.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase

Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K. & Nakayama, K., 12 1 2004, : : Nature Cell Biology. 6, 12, p. 1229-1235 7 p.

研究成果: ジャーナルへの寄稿記事

320 引用 (Scopus)
49 引用 (Scopus)

Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones

Hatakeyama, S., Matsumoto, M., Yada, M. & Nakayama, K., 6 1 2004, : : Genes to Cells. 9, 6, p. 533-548 16 p.

研究成果: ジャーナルへの寄稿記事

70 引用 (Scopus)

Minimizing the Cross Validation Error to Mix Kernel Matrices of Heterogeneous Biological Data

Tsuda, K., Uda, S., Kin, T. & Asai, K., 2004, : : Neural Processing Letters. 19, p. 63-72

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Molecular clearance of ataxin-3 is regulated by a mammalian E4

Matsumoto, M., Yada, M., Hatakeyama, S., Ishimoto, H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M. & Nakayama, K. I., 2 11 2004, : : EMBO Journal. 23, 3, p. 659-669 11 p.

研究成果: ジャーナルへの寄稿記事

113 引用 (Scopus)

Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia

Takaki, H., Kikuta, R., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 7 1 2004, : : American Journal of Medical Genetics - Neuropsychiatric Genetics. 128 B, 1, p. 6-14 9 p.

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy

Hatakeyama, S., Matsumoto, M., Kamura, T., Murayama, M., Chui, D. H., Planel, E., Takahashi, R., Nakayama, K. I. & Takashima, A., 10 1 2004, : : Journal of Neurochemistry. 91, 2, p. 299-307 9 p.

研究成果: ジャーナルへの寄稿記事

90 引用 (Scopus)

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R. C., Conaway, J. W. & Nakayama, K. I., 12 15 2004, : : Genes and Development. 18, 24, p. 3055-3065 11 p.

研究成果: ジャーナルへの寄稿記事

316 引用 (Scopus)
2003

Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a

Kaneko, C., Hatakeyama, S., Matsumoto, M., Yada, M., Nakayama, K. & Nakayama, K., 1 10 2003, : : Biochemical and Biophysical Research Communications. 300, 2, p. 297-304 8 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Glutamate receptor genes as candidates for schizophrenia susceptibility

Fukumaki, Y. & Shibata, H., 10 1 2003, : : Drug Development Research. 60, 2, p. 137-151 15 p.

研究成果: ジャーナルへの寄稿評論記事

6 引用 (Scopus)

Positive association of the AMPA receptor subunit GluR4 gene (GRIA4) haplotype with schizophrenia: Linkage disequilibrium mapping using SNPs evenly distributed across the gene region

Makino, C., Fujii, Y., Kikuta, R., Hirata, N., Tani, A., Shibata, A., Ninomiya, H., Tashiro, N., Shibata, H. & Fukumaki, Y., 1 1 2003, : : American Journal of Medical Genetics - Neuropsychiatric Genetics. 116 B, 1, p. 17-22 6 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia

Fujii, Y., Shibata, H., Kikuta, R., Makino, C., Tani, A., Hirata, N., Shibata, A., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 6 2003, : : Psychiatric Genetics. 13, 2, p. 71-76 6 p.

研究成果: ジャーナルへの寄稿記事

99 引用 (Scopus)

Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1

Oshikawa, K., Matsumoto, M., Yada, M., Kamura, T., Hatakeyama, S. & Nakayama, K. I., 4 18 2003, : : Biochemical and Biophysical Research Communications. 303, 4, p. 1209-1216 8 p.

研究成果: ジャーナルへの寄稿記事

52 引用 (Scopus)
2002

Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia

Shibata, H., Shibata, A., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 12 15 2002, : : Psychiatry research. 113, 1-2, p. 59-67 9 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)

Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): Implications for schizophrenia

Tani, A., Kikuta, R., Itoh, K., Joo, A., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 11 1 2002, : : Schizophrenia research. 58, 1, p. 83-86 4 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)
2001

Analysis of polyprenols by supercritical fluid chromatography

Bamba, T., Fukusaki, E. I., Nakazawa, Y., Sato, H., Ute, K., Kitayama, T. & Kobayashi, A., 12 1 2001, : : KOBUNSHI RONBUNSHU. 58, 12, p. 642-649 8 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene (DRD4) with schizophrenia and personality traits

Mitsuyasu, H., Hirata, N., Sakai, Y., Shibata, H., Takeda, Y., Ninomiya, H., Kawasaki, H., Tashiro, N. & Fukumaki, Y., 3 10 2001, : : Journal of Human Genetics. 46, 1, p. 26-31 6 p.

研究成果: ジャーナルへの寄稿記事

71 引用 (Scopus)

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia

Shibata, H., Joo, A., Fujii, Y., Tani, A., Makino, C., Hirata, N., Kikuta, R., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 10 30 2001, : : Psychiatric Genetics. 11, 3, p. 139-144 6 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)

High-resolution analysis of polyprenols by supercritical fluid chromatography

Bamba, T., Fukusaki, E., Kajiyama, S., Ute, K., Kitayama, T. & Kobayashi, A., 3 9 2001, : : Journal of Chromatography A. 911, 1, p. 113-117 5 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): Analysis of association with schizophrenia

Joo, A., Shibata, H., Ninomiya, H., Kawasaki, H., Tashiro, N. & Fukumaki, Y., 3 14 2001, : : Molecular Psychiatry. 6, 2, p. 186-192 7 p.

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)
2000

Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome

Yamanaka, A., Hatakeyama, S., Kominami, K. I., Kitagawa, M., Matsumoto, M. & Nakayama, K. I., 1 1 2000, : : Molecular biology of the cell. 11, 8, p. 2821-2831 11 p.

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)

Erratum: A novel protein with RNA-binding motifs interacts with ataxin-2 (Human Molecular Genetics (2000) vol.9 (1303-1313))

Shibata, H., Huynh, D. P. & Pulst, S. M., 8 17 2000, : : Human Molecular Genetics. 9, 12, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Molecular analysis of α-thalassemia in Nepal: Correlation with malaria endemicity

Sakai, Y., Kobayashi, S., Shibata, H., Furuumi, H., Endo, T., Fucharoen, S., Hamano, S., Acharya, G. P., Kawasaki, T. & Fukumaki, Y., 1 1 2000, : : Journal of Human Genetics. 45, 3, p. 127-132 6 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Targeted disruption of Skp2 results in accumulation of cyclin E and p27 (Kip1), polyploidy and centrosome overduplication

Nakayama, K., Nagahama, H., Minamishima, Y. A., Matsumoto, M., Nakamichi, I., Kitagawa, K., Shirane, M., Tsunematsu, R., Tsukiyama, T., Ishida, N., Kitagawa, M., Nakayama, K. I. & Hatakeyama, S., 5 2 2000, : : EMBO Journal. 19, 9, p. 2069-2081 13 p.

研究成果: ジャーナルへの寄稿記事

594 引用 (Scopus)

The ortholog of human ataxin-2 is essential for early embryonic patterning in C. elegans

Kiehl, T. R., Shibata, H. & Pulst, S. M., 1 1 2000, : : Journal of Molecular Neuroscience. 15, 3, p. 231-241 11 p.

研究成果: ジャーナルへの寄稿記事

41 引用 (Scopus)
1999

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. I. & Nakayama, K., 5 4 1999, : : EMBO Journal. 18, 9, p. 2401-2410 10 p.

研究成果: ジャーナルへの寄稿記事

446 引用 (Scopus)

Molecular dissection of the interactions among IκBα, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IκBα

Hattori, K., Hatakeyama, S., Shirane, M., Matsumoto, M. & Nakayama, K. I., 10 15 1999, : : Journal of Biological Chemistry. 274, 42, p. 29641-29647 7 p.

研究成果: ジャーナルへの寄稿記事

34 引用 (Scopus)

Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1

Hatakeyama, S., Kitagawa, M., Nakayama, K., Shirane, M., Matsumoto, M., Hattori, K., Higashi, H., Nakano, H., Okumura, K., Onoé, K., Good, R. A. & Nakayama, K. I., 3 30 1999, : : Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 3859-3863 5 p.

研究成果: ジャーナルへの寄稿記事

168 引用 (Scopus)