トランスオミクス医学研究センター

研究成果

Biosynthetic pathway for the C45 polyprenol, solanesol, in tobacco

Fukusaki, E., Takeno, S., Bamba, T., Okumoto, H., Katto, H., Kajiyama, S. & Kobayashi, A., 9 1 2004, : : Bioscience, Biotechnology and Biochemistry. 68, 9, p. 1988-1990 3 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

Biochemical characterization of CYP505D6, a self-sufficient cytochrome P450 from the white-rot fungus Phanerochaete chrysosporium

Sakai, K., Matsuzaki, F., Wise, L., Sakai, Y., Jindou, S., Ichinose, H., Takaya, N., Kato, M., Wariishi, H. & Shimizu, M., 11 1 2018, : : Applied and environmental microbiology. 84, 22, e01091-18.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1

Sasaki, F., Koga, T., Saeki, K., Okuno, T., Kazuno, S., Fujimura, T., Ohkawa, Y. & Yokomizo, T., 9 2017, : : PloS one. 12, 9, e0185133.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Biochemical analysis of nucleosome targeting by Tn5 transposase

Sato, S., Arimura, Y., Kujirai, T., Harada, A., Maehara, K., Nogami, J., Ohkawa, Y. & Kurumizaka, H., 8 1 2019, : : Open Biology. 9, 8, 190116.

研究成果: ジャーナルへの寄稿記事

公開

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Hosokawa, H., Romero-Wolf, M., Yui, M. A., Ungerbäck, J., Quiloan, M. L. G., Matsumoto, M., Nakayama, K. I., Tanaka, T. & Rothenberg, E. V., 12 1 2018, : : Nature Immunology. 19, 12, p. 1427-1440 14 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes

Nishida, W., Nakamura, M., Mori, S., Takahashi, M., Ohkawa, Y., Tadokoro, S., Yoshida, K., Hiwada, K., Hayashi, K. N. I. & Sobue, K., 3 1 2002, : : Journal of Biological Chemistry. 277, 9, p. 7308-7317 10 p.

研究成果: ジャーナルへの寄稿記事

84 引用 (Scopus)

A strategy for large-scale phosphoproteomics and SRM-based validation of human breast cancer tissue samples

Narumi, R., Murakami, T., Kuga, T., Adachi, J., Shiromizu, T., Muraoka, S., Kume, H., Kodera, Y., Matsumoto, M., Nakayama, K., Miyamoto, Y., Ishitobi, M., Inaji, H., Kato, K. & Tomonaga, T., 11 2 2012, : : Journal of Proteome Research. 11, 11, p. 5311-5322 12 p.

研究成果: ジャーナルへの寄稿記事

67 引用 (Scopus)

Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia

Deng, X., Sagata, N., Takeuchi, N., Tanaka, M., Ninomiya, H., Iwata, N., Ozaki, N., Shibata, H. & Fukumaki, Y., 7 18 2008, : : BMC Psychiatry. 8, 58.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia

Deng, X., Shibata, H., Takeuchi, N., Rachi, S., Sakai, M., Ninomiya, H., Iwata, N., Ozaki, N. & Fukumaki, Y., 4 5 2007, : : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 144, 3, p. 271-278 8 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia

Shibata, H., Aramaki, T., Sakai, M., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. & Fukumaki, Y., 1 30 2006, : : Psychiatry research. 141, 1, p. 39-51 13 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia

Shibata, H., Shibata, A., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 12 15 2002, : : Psychiatry research. 113, 1-2, p. 59-67 9 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia

Shibata, H., Joo, A., Fujii, Y., Tani, A., Makino, C., Hirata, N., Kikuta, R., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 10 30 2001, : : Psychiatric Genetics. 11, 3, p. 139-144 6 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)

Association study of polymorphisms in the excitatory amino acid transporter 2 gene (SLC1A2) with schizophrenia

Deng, X., Shibata, H., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. & Fukumaki, Y., 8 6 2004, : : BMC Psychiatry. 4, 21.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Lee, H. J., Song, J. Y., Kim, J. W., Jin, S. Y., Hong, M. S., Park, J. K., Chung, J. H., Shibata, H. & Fukumaki, Y., 8 31 2005, : : Behavioral and Brain Functions. 1, 15.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia

Arai, S., Shibata, H., Sakai, M., Ninomiya, H., Lwata, N., Ozaki, N. & Fukumaki, Y., 2 1 2009, : : Psychiatric Genetics. 19, 1, p. 6-13 8 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene (DRD4) with schizophrenia and personality traits

Mitsuyasu, H., Hirata, N., Sakai, Y., Shibata, H., Takeda, Y., Ninomiya, H., Kawasaki, H., Tashiro, N. & Fukumaki, Y., 3 10 2001, : : Journal of Human Genetics. 46, 1, p. 26-31 6 p.

研究成果: ジャーナルへの寄稿記事

71 引用 (Scopus)

A rat monoclonal antibody against the chromatin remodeling factor CHD5

Yoshimura, S., Yoshimi, T., Ohkawa, Y., Azuma, M. & Tachibana, T., 2 1 2010, : : Hybridoma. 29, 1, p. 63-66 4 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

A panel of specific monoclonal antibodies directed against various phosphorylated histones H3

Yoshimi, T., Ohkawa, Y., Azuma, M. & Tachibana, T., 4 1 2013, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 32, 2, p. 119-124 6 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

A one-step immunostaining method to visualize rodent muscle fiber type within a single specimen

Sawano, S., Komiya, Y., Ichitsubo, R., Ohkawa, Y., Nakamura, M., Tatsumi, R., Ikeuchi, Y. & Mizunoya, W., 11 2016, : : PloS one. 11, 11, 0166080.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

Araki, M., Kurihara, M., Kinoshita, S., Awane, R., Sato, T., Ohkawa, Y. & Inoue, Y. H., 1 1 2019, : : DMM Disease Models and Mechanisms. 12, 6, dmm037721.

研究成果: ジャーナルへの寄稿記事

公開
3 引用 (Scopus)

Anovel serum metabolomics-based diagnostic approach to pancreatic cancer

Kobayashi, T., Nishiumi, S., Ikeda, A., Yoshie, T., Sakai, A., Matsubara, A., Izumi, Y., Tsumura, H., Tsuda, M., Nishisaki, H., Hayashi, N., Kawano, S., Fujiwara, Y., Minami, H., Takenawa, T., Azuma, T. & Yoshida, M., 4 1 2013, : : Cancer Epidemiology Biomarkers and Prevention. 22, 4, p. 571-579 9 p.

研究成果: ジャーナルへの寄稿記事

101 引用 (Scopus)

A novel missense variant (Gln220Arg) of GNB4 encoding guanine nucleotide-binding protein, subunit beta-4 in a Japanese family with autosomal dominant motor and sensory neuropathy

Miura, S., Morikawa, T., Fujioka, R., Noda, K., Kosaka, K., Taniwaki, T. & Shibata, H., 9 2017, : : European Journal of Medical Genetics. 60, 9, p. 474-478 5 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

A novel missense mutation of RYR1 in familial idiopathic hyper CK-emia

Sano, K., Miura, S., Fujiwara, T., Fujioka, R., Yorita, A., Noda, K., Kida, H., Azuma, K., Kaieda, S., Yamamoto, K., Taniwaki, T., Fukumaki, Y. & Shibata, H., 9 15 2015, : : Journal of the Neurological Sciences. 356, 1-2, p. 142-147 6 p., 13864.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

A novel frameshift mutation of DDHD1 in a Japanese patient with autosomal recessive spastic paraplegia

Miura, S., Morikawa, T., Fujioka, R., Kosaka, K., Yamada, K., Hattori, G., Motomura, M., Taniwaki, T. & Shibata, H., 8 1 2016, : : European Journal of Medical Genetics. 59, 8, p. 413-416 4 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

A novel crude oil emulsifier excreted in the culture supernatant of a marine bacterium, Myroides sp. strain SM1

Maneerat, S., Bamba, T., Harada, K., Kobayashi, A., Yamada, H. & Kawai, F., 3 1 2006, : : Applied Microbiology and Biotechnology. 70, 2, p. 254-259 6 p.

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)

An optogenetic system for interrogating the temporal dynamics of Akt

Katsura, Y., Kubota, H., Kunida, K., Kanno, A., Kuroda, S. & Ozawa, T., 10 1 2015, : : Scientific reports. 5, 14589.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

An improved restriction enzyme accessibility assay for analyzing changes in chromatin structure in samples of limited cell number

Ohkawa, Y., Mallappa, C., Vallaster, C. S. D. & Imbalzano, A. N., 1 2 2012, Myogenesis: Methods and Protocols. DiMario, J. (版). p. 531-542 12 p. (Methods in Molecular Biology; 巻数 798).

研究成果: 著書/レポートタイプへの貢献

7 引用 (Scopus)

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. I. & Nakayama, K., 5 4 1999, : : EMBO Journal. 18, 9, p. 2401-2410 10 p.

研究成果: ジャーナルへの寄稿記事

446 引用 (Scopus)

A new targeted capture method using bacterial artificial chromosome (BAC) libraries as baits for sequencing relatively large genes

Koganebuchi, K., Gakuhari, T., Takeshima, H., Sato, K., Fujii, K., Kumabe, T., Kasagi, S., Sato, T., Tajima, A., Shibata, H., Ogawa, M. & Oota, H., 7 2018, : : PloS one. 13, 7, e0200170.

研究成果: ジャーナルへの寄稿記事

Analysis of polyprenols by supercritical fluid chromatography

Bamba, T., Fukusaki, E. I., Nakazawa, Y., Sato, H., Ute, K., Kitayama, T. & Kobayashi, A., 12 1 2001, : : KOBUNSHI RONBUNSHU. 58, 12, p. 642-649 8 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Analysis of cellular signal transduction from an information theoretic approach

Uda, S. & Kuroda, S., 3 1 2016, : : Seminars in Cell and Developmental Biology. 51, p. 24-31 8 p.

研究成果: ジャーナルへの寄稿評論記事

13 引用 (Scopus)

Analysis of CDMA systems that are characterized by eigenvalue spectrum

Takeda, K., Uda, S. & Kabashima, Y., 2006, : : Europhysics Letters. 76, p. 1193-1199

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

An albino mutant of the Japanese rat snake (Elaphe climacophora) carries a nonsense mutation in the tyrosinase gene

Iwanishi, S., Zaitsu, S., Shibata, H. & Nitasaka, E., 1 1 2018, : : Genes and Genetic Systems. 93, 4, p. 163-167 5 p.

研究成果: ジャーナルへの寄稿記事

A metabolomics-based strategy for identification of gene targets for phenotype improvement and its application to 1-butanol tolerance in Saccharomyces cerevisiae

Teoh, S. T., Putri, S., Mukai, Y., Bamba, T. & Fukusaki, E., 9 15 2015, : : Biotechnology for Biofuels. 8, 1, 330.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

A metabolite of dietary glucosylceramide from pineapples improves the skin barrier function in hairless mice

Kuwata, T., Hashimoto, T., Ohto, N., Kuwahara, H., Lee, J. W., Bamba, T. & Mizuno, M., 3 1 2017, : : Journal of Functional Foods. 30, p. 228-236 9 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Ameliorating effects of D-47, a newly developed compound, on lipid metabolism in an animal model of familial hypercholesterolemia (WHHLMI rabbits)

Tamura, S., Koike, Y., Takeda, H., Koike, T., Izumi, Y., Nagasaka, R., Tsunoda, T., Tori, M., Ogawa, K., Bamba, T. & Shiomi, M., 3 5 2018, : : European Journal of Pharmacology. 822, p. 147-153 7 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Alternative mRNA splicing in three venom families underlying a possible production of divergent venom proteins of the habu snake, protobothrops flavoviridis

Ogawa, T., Oda-Ueda, N., Hisata, K., Nakamura, H., Chijiwa, T., Hattori, S., Isomoto, A., Yugeta, H., Yamasaki, S., Fukumaki, Y., Ohno, M., Satoh, N. & Shibata, H., 10 9 2019, : : Toxins. 11, 10, 581.

研究成果: ジャーナルへの寄稿記事

公開

Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development

Miyabayashi, K., Shima, Y., Inoue, M., Sato, T., Baba, T., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 5 1 2017, : : Sexual Development. 11, 2, p. 53-63 11 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Alterations in Docosahexaenoic Acid-Related Lipid Cascades in Inflammatory Bowel Disease Model Mice

Nishiumi, S., Izumi, Y. & Yoshida, M., 6 1 2018, : : Digestive Diseases and Sciences. 63, 6, p. 1485-1496 12 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice

Niki, S., Oshikawa, K., Mouri, Y., Hirota, F., Matsushima, A., Yano, M., Han, H., Bando, Y., Izumi, K., Matsumoto, M., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 5 1 2006, : : Journal of Clinical Investigation. 116, 5, p. 1292-1301 10 p.

研究成果: ジャーナルへの寄稿記事

79 引用 (Scopus)

A large-scale targeted proteomics assay resource based on an in vitro human proteome

Matsumoto, M., Matsuzaki, F., Oshikawa, K., Goshima, N., Mori, M., Kawamura, Y., Ogawa, K., Fukuda, E., Nakatsumi, H., Natsume, T., Fukui, K., Horimoto, K., Nagashima, T., Funayama, R., Nakayama, K. & Nakayama, K. I., 2 28 2017, : : Nature Methods. 14, 3, p. 251-258 8 p.

研究成果: ジャーナルへの寄稿記事

29 引用 (Scopus)

Akt1-mediated Gata3 phosphorylation controls the repression of IFNÎ 3 in memory-type Th2 cells

Hosokawa, H., Tanaka, T., Endo, Y., Kato, M., Shinoda, K., Suzuki, A., Motohashi, S., Matsumoto, M., Nakayama, K. I. & Nakayama, T., 4 7 2016, : : Nature communications. 7, 11289.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

A high-resolution PAC and BAC map of the SCA2 region

Nechiporuk, T., Nechiporuk, A., Sahba, S., Figueroa, K., Shibata, H., Chen, X. N., Korenberg, J. R., De Jong, P. & Pulst, S. M., 9 15 1997, : : Genomics. 44, 3, p. 321-329 9 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

A high phosphorus diet affects lipid metabolism in rat liver: A DNA microarray analysis

Chun, S., Bamba, T., Suyama, T., Ishijima, T., Fukusaki, E., Abe, K. & Nakai, Y., 5 2016, : : PloS one. 11, 5, e0155386.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

A highly sensitive determination method for acrylamide in beverages, grains, and confectioneries by supercritical fluid chromatography tandem mass spectrometry

Yoshioka, T., Izumi, Y., Nagatomi, Y., Miyamoto, Y., Suzuki, K. & Bamba, T., 10 1 2019, : : Food Chemistry. 294, p. 486-492 7 p.

研究成果: ジャーナルへの寄稿記事

Agplus: A rapid and flexible tool for aggregation plots

Maehara, K. & Ohkawa, Y., 7 31 2015, : : Bioinformatics. 31, 18, p. 3046-3047 2 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)
27 引用 (Scopus)

A genome-wide analysis identifies a Notch-RBP-Jk-IL-7Ra axis that controls IL-17-Producing γδ T cell homeostasis in mice

Nakamura, M., Shibata, K., Hatano, S., Sato, T., Ohkawa, Y., Yamada, H., Ikuta, K. & Yoshikai, Y., 1 1 2015, : : Journal of Immunology. 194, 1, p. 243-251 9 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen

Oshikawa, K., Matsumoto, M., Kodama, M., Shimizu, H. & Nakayama, K. I., 3 5 2020, : : Oncogene. 39, 10, p. 2170-2186 17 p.

研究成果: ジャーナルへの寄稿記事

Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release

Obata, Y., Kita, S., Koyama, Y., Fukuda, S., Takeda, H., Takahashi, M., Fujishima, Y., Nagao, H., Masuda, S., Tanaka, Y., Nakamura, Y., Nishizawa, H., Funahashi, T., Ranscht, B., Izumi, Y., Bamba, T., Fukusaki, E., Hanayama, R., Shimada, S., Maeda, N. および1人, Shimomura, I., 4 19 2018, : : JCI Insight. 3, 8

研究成果: ジャーナルへの寄稿記事

公開
19 引用 (Scopus)