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研究成果 2005 2019

  • 502 引用
  • 14 h指数
  • 44 記事
  • 1 評論記事
フィルター
記事
2019
2 引用 (Scopus)

A chromatin integration labelling method enables epigenomic profiling with lower input

Harada, A., Maehara, K., Handa, T., Arimura, Y., Nogami, J., Hayashi-Takanaka, Y., Shirahige, K., Kurumizaka, H., Kimura, H. & Ohkawa, Y., 2 1 2019, : : Nature Cell Biology. 21, 2, p. 287-296 10 p.

研究成果: ジャーナルへの寄稿記事

Epigenomics
Chromatin
Chromatin Immunoprecipitation
Histone Code
Immunoprecipitation

Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires HeS1 to bind diverse DNA sites

Noguchi, Y. T., Nakamura, M., Hino, N., Nogami, J., Tsuji, S., Sato, T., Zhang, L., Tsujikawa, K., Tanaka, T., Izawa, K., Okada, Y., Doi, T., Kokubo, H., Harada, A., Uezumi, A., Gessler, M., Ohkawa, Y. & Fukada, S. I., 2 1 2019, : : Development (Cambridge). 146, 4, dev163618.

研究成果: ジャーナルへの寄稿記事

公開
Muscle Cells
Stem Cells
DNA
Myogenin
Chromatin

Locomotor Training Increases Synaptic Structure With High NGL-2 Expression After Spinal Cord Hemisection

Kobayakawa, K., DePetro, K. A., Zhong, H., Pham, B., Hara, M., Harada, A., Nogami, J., Ohkawa, Y. & Edgerton, V. R., 1 1 2019, : : Neurorehabilitation and Neural Repair.

研究成果: ジャーナルへの寄稿記事

Spinal Cord
Synapses
RNA
Synaptophysin
Gene Ontology
2018

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., 12 1 2018, : : Nature communications. 9, 1, 1400.

研究成果: ジャーナルへの寄稿記事

skeletal muscle
chromatin
Nucleosomes
regeneration
Histones
1 引用 (Scopus)

Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders

Shiraishi, K., Shindo, A., Harada, A., Kurumizaka, H., Kimura, H., Ohkawa, Y. & Matsuyama, H., 1 1 2018, : : Andrology. 6, 1, p. 158-165 8 p.

研究成果: ジャーナルへの寄稿記事

Azoospermia
Spermatogenesis
Histones
Testis
Proliferating Cell Nuclear Antigen
4 引用 (Scopus)

Sensitive detection of fluorescence in western blotting by merging images

Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 1 2018, : : PloS one. 13, 1, e0191532.

研究成果: ジャーナルへの寄稿記事

Merging
Western blotting
Fluorescence
Western Blotting
fluorescence
2017
6 引用 (Scopus)

Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, : : Nucleic acids research. 45, 15, p. 8758-8772 15 p.

研究成果: ジャーナルへの寄稿記事

DNA Helicases
Embryonic Stem Cells
Chromatin
Gene Expression
Histones
5 引用 (Scopus)

Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8

Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 25 2017, : : Biochemistry. 56, 16, p. 2184-2196 13 p.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Histones
Crystal structure
Epigenomics
Thermodynamic stability
10 引用 (Scopus)

Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury

Yokota, K., Kobayakawa, K., Saito, T., Hara, M., Kijima, K., Ohkawa, Y., Harada, A., Okazaki, K., Ishihara, K., Yoshida, S., Kudo, A., Iwamoto, Y. & Okada, S., 3 1 2017, : : American Journal of Pathology. 187, 3, p. 639-653 15 p.

研究成果: ジャーナルへの寄稿記事

Pericytes
Spinal Cord Injuries
Cicatrix
Monocytes
Macrophages
21 引用 (Scopus)

Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis

Ueda, J., Harada, A., Urahama, T., Machida, S., Maehara, K., Hada, M., Makino, Y., Nogami, J., Horikoshi, N., Osakabe, A., Taguchi, H., Tanaka, H., Tachiwana, H., Yao, T., Yamada, M., Iwamoto, T., Isotani, A., Ikawa, M., Tachibana, T., Okada, Y. および4人Kimura, H., Ohkawa, Y., Kurumizaka, H. & Yamagata, K., 1 17 2017, : : Cell Reports. 18, 3, p. 593-600 8 p.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Essential Genes
Spermatogenesis
Germ Cells
Histones
10 引用 (Scopus)

The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation

Kudou, K., Komatsu, T., Nogami, J., Maehara, K., Harada, A., Saeki, H., Oki, E., Maehara, Y. & Ohkawa, Y., 1 1 2017, : : Open Biology. 7, 9, 170119.

研究成果: ジャーナルへの寄稿記事

Myoblasts
Methyltransferases
Muscle
Skeletal Muscle
Maintenance
2016
14 引用 (Scopus)

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., 3 1 2016, : : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

研究成果: ジャーナルへの寄稿記事

Histone Code
Endogenous Retroviruses
Stem cells
Histones
Clustered Regularly Interspaced Short Palindromic Repeats
17 引用 (Scopus)

Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis

Urahama, T., Harada, A., Maehara, K., Horikoshi, N., Sato, K., Sato, Y., Shiraishi, K., Sugino, N., Osakabe, A., Tachiwana, H., Kagawa, W., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 1 15 2016, : : Epigenetics and Chromatin. 9, 1, 51.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Transcription Initiation Site
Histones
Testis
Seminiferous Tubules
11 引用 (Scopus)

Histone H4 lysine 20 acetylation is associated with gene repression in human cells

Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H. & Isaka, Y., 4 11 2016, : : Scientific reports. 6, 24318.

研究成果: ジャーナルへの寄稿記事

Acetylation
Histones
Lysine
Genes
Transcription Initiation Site
3 引用 (Scopus)

Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas

Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., 10 1 2016, : : PloS one. 11, 10, e0165473.

研究成果: ジャーナルへの寄稿記事

immunoglobulin genes
Immunoglobulin Genes
hybridomas
Hybridomas
Immunoglobulins
2015
19 引用 (Scopus)

Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies

Hayashi-Takanaka, Y., Maehara, K., Harada, A., Umehara, T., Yokoyama, S., Obuse, C., Ohkawa, Y., Nozaki, N. & Kimura, H., 12 1 2015, : : Chromosome Research. 23, 4, p. 753-766 14 p.

研究成果: ジャーナルへの寄稿記事

Histone Code
Acetylation
Histones
Monoclonal Antibodies
Epigenomics
17 引用 (Scopus)

Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle

Harada, A., Maehara, K., Sato, Y., Konno, D., Tachibana, T., Kimura, H. & Ohkawa, Y., 1 30 2015, : : Nucleic acids research. 43, 2, p. 775-786 12 p.

研究成果: ジャーナルへの寄稿記事

Histones
Skeletal Muscle
Genes
Histone Code
Nucleic Acid Regulatory Sequences
5 引用 (Scopus)

Relationship between the risk for a shrimp allergy and freshness or cooking

Usui, M., Harada, A., Yasumoto, S., Sugiura, Y., Nishidai, A., Ikarashi, M., Takaba, H., Miyasaki, T., Azakami, H. & Kondo, M., 1 1 2015, : : Bioscience, Biotechnology and Biochemistry. 79, 10, p. 1698-1701 4 p.

研究成果: ジャーナルへの寄稿記事

Allergies
Tropomyosin
Cooking
Hypersensitivity
Meats
15 引用 (Scopus)

Spatial re-organization of myogenic regulatory sequences temporally controls gene expression

Harada, A., Mallappa, C., Okada, S., Butler, J. T., Baker, S. P., Lawrence, J. B., Ohkawa, Y. & Imbalzano, A. N., 2 27 2015, : : Nucleic acids research. 43, 4, p. 2008-2021 14 p.

研究成果: ジャーナルへの寄稿記事

Gene Expression
Genes
Muscle Development
Myogenin
Chromatin Assembly and Disassembly
17 引用 (Scopus)

Tissue-specific expression of histone H3 variants diversified after species separation

Maehara, K., Harada, A., Sato, Y., Matsumoto, M., Nakayama, K., Kimura, H. & Ohkawa, Y., 9 17 2015, : : Epigenetics and Chromatin. 8, 1, 35.

研究成果: ジャーナルへの寄稿記事

Histones
Chromatin
Pseudogenes
Genome
Genes
2014
2 引用 (Scopus)

Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2

Tanaka, M., Yamaguchi, M., Shiota, M., Kawamoto, Y., Takahashi, K., Inagaki, A., Osada-Oka, M., Harada, A., Wanibuchi, H., Izumi, Y., Miura, K., Iwao, H. & Ohkawa, Y., 8 1 2014, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 4, p. 261-269 9 p.

研究成果: ジャーナルへの寄稿記事

Fibroblast Growth Factor 2
Monoclonal Antibodies
Neutralizing Antibodies
Lymph Nodes
Receptor, Fibroblast Growth Factor, Type 2

Generation of a monoclonal antibody for INI1/hSNF5/BAF47

Harada, A., Hayashi, M., Kuniyoshi, Y., Semba, Y., Sugahara, S., Tachibana, T., Ohkawa, Y. & Fujita, M., 2 1 2014, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 1, p. 49-51 3 p.

研究成果: ジャーナルへの寄稿記事

Cell Differentiation
Monoclonal Antibodies
Chromatin Assembly and Disassembly
Antibodies
Gene Expression Regulation
14 引用 (Scopus)

Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions

Tanaka, M., Mun, S., Harada, A., Ohkawa, Y., Inagaki, A., Sano, S., Takahashi, K., Izumi, Y., Osada-Oka, M., Wanibuchi, H., Yamagata, M., Yukimura, T., Miura, K., Shiota, M. & Iwao, H., 5 6 2014, : : PloS one. 9, 5, e96785.

研究成果: ジャーナルへの寄稿記事

HSC70 Heat-Shock Proteins
cell viability
Cell Survival
Cells
Degradation
CCAAT-Enhancer-Binding Proteins
Monoclonal Antibodies
Protein Isoforms
Leucine Zippers
DNA
2013
7 引用 (Scopus)

A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples

Maehara, K., Odawara, J., Harada, A., Yoshimi, T., Nagao, K., Obuse, C., Akashi, K., Tachibana, T., Sakata, T. & Ohkawa, Y., 1 1 2013, : : Nucleic acids research. 41, 1, p. 54-62 9 p.

研究成果: ジャーナルへの寄稿記事

Encyclopedias
Chromatin Immunoprecipitation
RNA Polymerase III
RNA Polymerase II
DNA
15 引用 (Scopus)

Contribution of structural reversibility to the heat stability of the tropomyosin shrimp allergen

Usui, M., Harada, A., Ishimaru, T., Sakumichi, E., Saratani, F., Sato-Minami, C., Azakami, H., Miyasaki, T. & Hanaoka, K., 6 12 2013, : : Bioscience, Biotechnology and Biochemistry. 77, 5, p. 948-953 6 p.

研究成果: ジャーナルへの寄稿記事

Tropomyosin
Allergens
Hot Temperature
Heating
Cooling
2012
63 引用 (Scopus)

Chd2 interacts with H3.3 to determine myogenic cell fate

Harada, A., Okada, S., Konno, D., Odawara, J., Yoshimi, T., Yoshimura, S., Kumamaru, H., Saiwai, H., Tsubota, T., Kurumizaka, H., Akashi, K., Tachibana, T., Imbalzano, A. N. & Ohkawa, Y., 7 4 2012, : : EMBO Journal. 31, 13, p. 2994-3007 14 p.

研究成果: ジャーナルへの寄稿記事

DNA Helicases
Genes
Cell Differentiation
Chromatin Assembly and Disassembly
Essential Genes
2011
22 引用 (Scopus)

Flow cytometric sorting of neuronal and glial nuclei from central nervous system tissue

Okada, S., Saiwai, H., Kumamaru, H., Kubota, K., Harada, A., Yamaguchi, M., Iwamoto, Y. & Ohkawa, Y., 2 1 2011, : : Journal of cellular physiology. 226, 2, p. 552-558 7 p.

研究成果: ジャーナルへの寄稿記事

Nerve Tissue
Neurology
Sorting
Neuroglia
Nucleoproteins
4 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Hsp72

Tanaka, M., Shiota, M., Okada, S., Harada, A., Odawara, J., Mun, S., Iwao, H. & Ohkawa, Y., 8 1 2011, : : Hybridoma. 30, 4, p. 397-400 4 p.

研究成果: ジャーナルへの寄稿記事

HSP70 Heat-Shock Proteins
Monoclonal Antibodies
Cytoplasm
Heat-Shock Response
Proteins
19 引用 (Scopus)

The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach

Odawara, J., Harada, A., Yoshimi, T., Maehara, K., Tachibana, T., Okada, S., Akashi, K. & Ohkawa, Y., 10 20 2011, : : BMC Genomics. 12, 516.

研究成果: ジャーナルへの寄稿記事

RNA Polymerase II
Phosphorylation
Genome
Messenger RNA
Genes
2010
3 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Chd2

Harada, A., Yoshimura, S., Odawara, J., Azuma, M., Okada, S., Nakamura, M., Tachibana, T. & Ohkawa, Y., 4 1 2010, : : Hybridoma. 29, 2, p. 173-177 5 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Gene Expression
Euchromatin
Chromatin Assembly and Disassembly
Antibodies
6 引用 (Scopus)

Generation of a rat monoclonal antibody specific for heat shock cognate protein 70

Shiota, M., Saiwai, H., Mun, S., Harada, A., Okada, S., Odawara, J., Tanaka, M., Iwao, H. & Ohkawa, Y., 10 1 2010, : : Hybridoma. 29, 5, p. 453-456 4 p.

研究成果: ジャーナルへの寄稿記事

HSC70 Heat-Shock Proteins
Monoclonal Antibodies
Cytoplasm
Molecular Chaperones
Antibodies
3 引用 (Scopus)

Monoclonal antibody specific for Dhx9/NDHII/RHA

Kotani, M., Harada, A., Odawara, J., Azuma, M., Okada, S., Nishiyama, Y., Nakamura, M., Tachibana, T. & Ohkawa, Y., 6 1 2010, : : Hybridoma. 29, 3, p. 259-261 3 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
RNA Helicases
Antibodies
Proteins
Adenosine Triphosphate
5 引用 (Scopus)

Production of a rat monoclonal antibody specific for Myf5

Harada, A., Okada, S., Odawara, J., Kumamaru, H., Saiwai, H., Aoki, M., Nakamura, M., Nishiyama, Y. & Ohkawa, Y., 2 1 2010, : : Hybridoma. 29, 1, p. 59-62 4 p.

研究成果: ジャーナルへの寄稿記事

Myogenic Regulatory Factors
Myoblasts
Monoclonal Antibodies
Helix-Loop-Helix Motifs
Myogenin
5 引用 (Scopus)

Rat monoclonal antibody specific for MyoD

Harada, A., Ohkawa, Y., Ao, S., Odawara, J., Okada, S., Azuma, M., Nishiyama, Y., Nakamura, M. & Tachibana, T., 6 1 2010, : : Hybridoma. 29, 3, p. 255-258 4 p.

研究成果: ジャーナルへの寄稿記事

Skeletal Muscle
Monoclonal Antibodies
Helix-Loop-Helix Motifs
Myogenic Regulatory Factors
Myoblasts
1 引用 (Scopus)

Rat monoclonal antibody specific for the chromatin remodeling factor, CHD1

Yoshimura, S., Harada, A., Odawara, J., Azuma, M., Okada, S., Nakamura, M., Ohkawa, Y. & Tachibana, T., 6 1 2010, : : Hybridoma. 29, 3, p. 237-240 4 p.

研究成果: ジャーナルへの寄稿記事

Chromatin Assembly and Disassembly
Monoclonal Antibodies
Mammals
Chromatin
Adenosine Triphosphate
89 引用 (Scopus)

The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury

Saiwai, H., Ohkawa, Y., Yamada, H., Kumamaru, H., Harada, A., Okano, H., Yokomizo, T., Iwamoto, Y. & Okada, S., 1 1 2010, : : American Journal of Pathology. 176, 5, p. 2352-2366 15 p.

研究成果: ジャーナルへの寄稿記事

Leukotriene B4
Neutrophil Infiltration
Spinal Cord Injuries
Leukotriene B4 Receptors
Leukocytes
2009
6 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Brm

Okada, S., Harada, A., Saiwai, H., Nakamura, M. & Ohkawa, Y., 12 1 2009, : : Hybridoma. 28, 6, p. 455-458 4 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Myoblasts
DNA Repair
Adenosine Triphosphatases
Skeletal Muscle
8 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Pax7

Harada, A., Okada, S., Saiwai, H., Aoki, M., Nakamura, M. & Ohkawa, Y., 12 1 2009, : : Hybridoma. 28, 6, p. 451-453 3 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Antibodies
Muscle Cells
Euchromatin
Ewing's Sarcoma
15 引用 (Scopus)

Production of a rat monoclonal antibody against Brg1

Ohkawa, Y., Harada, A., Nakamura, M., Yoshimura, S. & Tachibana, T., 12 1 2009, : : Hybridoma. 28, 6, p. 463-466 4 p.

研究成果: ジャーナルへの寄稿記事

Chromatin Assembly and Disassembly
Monoclonal Antibodies
Genes
Antibodies
Euchromatin
2008
14 引用 (Scopus)

Amyloid fibril formation of hen lysozyme depends on the instability of the C-helix (88-99)

Harada, A., Azakami, H. & Kato, A., 7 1 2008, : : Bioscience, Biotechnology and Biochemistry. 72, 6, p. 1523-1530 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Amyloid
Agglomeration
2007
8 引用 (Scopus)

Relationship between the stability of hen egg-white lysozymes mutated at sites designed to interact with α-helix dipoles and their secretion amounts in yeast

Harada, A., Yagi, H., Saito, A., Azakami, H. & Kato, A., 12 1 2007, : : Bioscience, Biotechnology and Biochemistry. 71, 12, p. 2952-2961 10 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Muramidase
Yeast
Yeasts
Aspartic Acid
2005
9 引用 (Scopus)

Characterization of recombinant amyloidogenic chicken cystatin mutant I66Q expressed in yeast

He, J., Song, Y., Ueyama, N., Harada, A., Azakami, H. & Kato, A., 4 1 2005, : : Journal of biochemistry. 137, 4, p. 477-485 9 p.

研究成果: ジャーナルへの寄稿記事

Yeast
Yeasts
Cystatins
Monomers
Dimers
4 引用 (Scopus)

Effect of EPS1 gene deletion in Saccharomyces cerevisiae on the secretion of foreign proteins which have disulfide bridges

He, J., Sakamoto, T., Song, Y., Saito, A., Harada, A., Azakami, H. & Kato, A., 4 25 2005, : : FEBS Letters. 579, 11, p. 2277-2283 7 p.

研究成果: ジャーナルへの寄稿記事

Gene Deletion
Cystatins
Muramidase
Disulfides
Yeast