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研究成果 1993 2019

フィルター
記事
1993
84 引用 (Scopus)
Lewis Acids
Regioselectivity
Molecular orbitals
Orbital calculations
Anions
7 引用 (Scopus)

Regioselective synthesis of maturone via Lewis acid catalyzed Diels-Alder reaction

Aso, M., Ojida, A., Yang, G. & Kanematsu, K., 1 1 1993, : : Heterocycles. 35, 1, p. 33-36 4 p.

研究成果: ジャーナルへの寄稿記事

Lewis Acids
Cycloaddition Reaction
Salts
furan
1994
9 引用 (Scopus)

Synthesis of annulated furans with various 3-substituents via a sequential furannulation/ene route

Ojida, A., Abe, A. & Kanematsu, K., 12 1 1994, : : Heterocycles. 38, 12, p. 2585-2588 4 p.

研究成果: ジャーナルへの寄稿記事

Furans
29 引用 (Scopus)

Total Syntheses of Marine Furanosesquiterpenoids, Tubipofurans

Ojida, A., Tanoue, F. & Kanematsu, K., 10 1 1994, : : Journal of Organic Chemistry. 59, 20, p. 5970-5976 7 p.

研究成果: ジャーナルへの寄稿記事

Anions
Salts
3-methylfuran
acetoxytubipofuran
furan
2002
102 引用 (Scopus)

Efficient fluorescent ATP-sensing based on coordination chemistry under aqueous neutral conditions

Ojida, A., Park, S. K., Mito-Oka, Y. & Hamachi, I., 8 26 2002, : : Tetrahedron Letters. 43, 35, p. 6193-6195 3 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphate
bis-dipicolylamine-Zinc(II)
anthracene
304 引用 (Scopus)

First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution

Ojida, A., Mito-Oka, Y., Inoue, M. A. & Hamachi, I., 6 5 2002, : : Journal of the American Chemical Society. 124, 22, p. 6256-6258 3 p.

研究成果: ジャーナルへの寄稿記事

Artificial Receptors
Peptides
Anthracene
Zinc
Fluorescence
43 引用 (Scopus)

Highly Enantioselective Reformatsky Reaction of Ketones: Chelation-Assisted Enantioface Discrimination

Ojida, A., Yamano, T., Taya, N. & Tasaka, A., 9 5 2002, : : Organic Letters. 4, 18, p. 3051-3054 4 p.

研究成果: ジャーナルへの寄稿記事

Cinchona Alkaloids
chelation
alkaloids
Enantioselectivity
Chelation
2003
101 引用 (Scopus)

Cross-linking strategy for molecular recognition and fluorescent sensing of a multi-phosphorylated peptide in aqueous solution

Ojida, A., Inoue, M. A., Mito-oka, Y. & Hamachi, I., 8 27 2003, : : Journal of the American Chemical Society. 125, 34, p. 10184-10185 2 p.

研究成果: ジャーナルへの寄稿記事

Molecular recognition
Peptides
Membrane Proteins
Artificial Receptors
Proteins
2004
50 引用 (Scopus)

C17,20-lyase inhibitors. Part 2: Design, synthesis and structure-activity relationships of (2-naphthylmethyl)-1H-imidazoles as novel C17,20-lyase inhibitors

Matsunaga, N., Kaku, T., Ojida, A., Tanaka, T., Hara, T., Yamaoka, M., Kusaka, M. & Tasaka, A., 8 15 2004, : : Bioorganic and Medicinal Chemistry. 12, 16, p. 4313-4336 24 p.

研究成果: ジャーナルへの寄稿記事

Imidazoles
Lyases
Biosynthesis
Structure-Activity Relationship
Liver
292 引用 (Scopus)
Artificial Receptors
Molecular recognition
Titration
Peptides
Zinc
165 引用 (Scopus)

Molecular recognition in a supramolecular hydrogel to afford a semi-wet sensor chip

Yoshimura, I., Miyahara, Y., Kasagi, N., Yamane, H., Ojida, A. & Hamachi, I., 10 6 2004, : : Journal of the American Chemical Society. 126, 39, p. 12204-12205 2 p.

研究成果: ジャーナルへの寄稿記事

Molecular recognition
Hydrogel
Hydrogels
Sensors
Immobilization
32 引用 (Scopus)

Phosphoprotein-selective recognition and staining in SDS-PAGE by bis-Zn(II)-dipycolylamine-appended anthracene

Ojida, A., Kohira, T. & Hamachi, I., 8 5 2004, : : Chemistry Letters. 33, 8, p. 1024-1025 2 p.

研究成果: ジャーナルへの寄稿記事

Phosphoproteins
Electrophoresis
Fluorescent Dyes
Gels
Fluorescence
30 引用 (Scopus)

Recognition and Fluorescence Sensing of Specific Amino Acid Residue on Protein Surface Using Designed Molecules

Ojida, A., Miyahara, Y., Kohira, T. & Hamachi, I., 5 6 2004, : : Biopolymers - Peptide Science Section. 76, 2, p. 177-184 8 p.

研究成果: ジャーナルへの寄稿記事

Amino acids
Membrane Proteins
Fluorescence
Proteins
Amino Acids
6 引用 (Scopus)

Stereocontrolled synthesis of (1S)-1-(1H-imidazol-4-yl)-1-(6-methoxy-2- naphthyl)-2-methylpropan-1-ol as a potent C17,20-lyase inhibitor

Ojida, A., Matsunaga, N., Kaku, T. & Tasaka, A., 5 24 2004, : : Tetrahedron Asymmetry. 15, 10, p. 1555-1559 5 p.

研究成果: ジャーナルへの寄稿記事

Lyases
imidazoles
inhibitors
Grignard reactions
Propanol
16 引用 (Scopus)

Synthetic studies on (1S)-1-(6,7-dimethoxy-2-naphthyl)-1-(1H-imidazol-4-yl) -2-methylpropan-1-ol as a selective C17,20-lyase inhibitor

Matsunaga, N., Kaku, T., Ojida, A. & Tasaka, A., 7 5 2004, : : Tetrahedron Asymmetry. 15, 13, p. 2021-2028 8 p.

研究成果: ジャーナルへの寄稿記事

Grignard reactions
Lyases
Ketones
imidazoles
ketones
2005
123 引用 (Scopus)

pH-responsive shrinkage/swelling of a supramolecular hydrogel composed of two small amphiphilic molecules

Zhou, S. L., Matsumoto, S., Tian, H. D., Yamane, H., Ojida, A., Kiyonaka, S. & Hamachi, I., 2 4 2005, : : Chemistry - A European Journal. 11, 4, p. 1130-1136 7 p.

研究成果: ジャーナルへの寄稿記事

Hydrogel
Hydrogels
Swelling
Molecules
Carboxylic Acids
64 引用 (Scopus)

Suzuki coupling for protein modification

Ojida, A., Tsutsumi, H., Kasagi, N. & Hamachi, I., 5 9 2005, : : Tetrahedron Letters. 46, 19, p. 3301-3305 5 p.

研究成果: ジャーナルへの寄稿記事

Cross Reactions
Biosensing Techniques
Fluorescent Dyes
Biosensors
Membrane Proteins
2006
152 引用 (Scopus)

Bis(Dpa-Zn II ) appended xanthone: Excitation ratiometric chemosensor for phosphate anions

Ojida, A., Nonaka, H., Miyahara, Y., Tamaru, S. I., Sada, K. & Hamachi, I., 8 18 2006, : : Angewandte Chemie - International Edition. 45, 33, p. 5518-5521 4 p.

研究成果: ジャーナルへの寄稿記事

Anions
Phosphates
Zinc
Negative ions
Fluorophores
34 引用 (Scopus)
Peptides
Phosphorylation
Proteins
Fluorescence
Phosphates
87 引用 (Scopus)

Design of dual-emission chemosensors for ratiometric detection of ATP derivatives

Ojida, A., Miyahara, Y., Wongkongkatep, J., Tamaru, S. I., Sada, K. & Hamachi, I., 11 9 2006, : : Chemistry - An Asian Journal. 1, 4, p. 555-563 9 p.

研究成果: ジャーナルへの寄稿記事

Nucleosides
Adenosine Triphosphate
Derivatives
Fluorescence
Apyrase
77 引用 (Scopus)

Effective disruption of phosphoprotein-protein surface interaction using Zn(II) dipicolylamine-based artificial receptors via two-point interaction

Ojida, A., Inoue, M. A., Mito-Oka, Y., Tsutsumi, H., Sada, K. & Hamachi, I., 2 15 2006, : : Journal of the American Chemical Society. 128, 6, p. 2052-2058 7 p.

研究成果: ジャーナルへの寄稿記事

Artificial Receptors
Phosphoproteins
Membrane Proteins
Proteins
Peptides
45 引用 (Scopus)

Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure

Tamamura, H., Ojida, A., Ogawa, T., Tsutsumi, H., Masuno, H., Nakashima, H., Yamamoto, N., Hamachi, I. & Fujii, N., 6 1 2006, : : Journal of Medicinal Chemistry. 49, 11, p. 3412-3415 4 p.

研究成果: ジャーナルへの寄稿記事

Chemokine Receptors
Molecular Weight
HIV
Drug Therapy
zinc(II) dipicolylamine
60 引用 (Scopus)

Label-free, real-time glycosyltransferase assay based on a fluorescent artificial chemosensor

Wongkongkatep, J., Miyahara, Y., Ojida, A. & Hamachi, I., 1 16 2006, : : Angewandte Chemie - International Edition. 45, 4, p. 665-668 4 p.

研究成果: ジャーナルへの寄稿記事

Glycosyltransferases
Labels
Assays
Screening
Fluorescence
139 引用 (Scopus)

Oligo-Asp Tag/Zn(II) complex probe as a new pair for labeling and fluorescence imaging of proteins

Ojida, A., Honda, K., Shinmi, D., Kiyonaka, S., Mori, Y. & Hamachi, I., 8 16 2006, : : Journal of the American Chemical Society. 128, 32, p. 10452-10459 8 p.

研究成果: ジャーナルへの寄稿記事

Optical Imaging
Labeling
Fluorescence
Proteins
Imaging techniques

Organic chemistry for creation and regulation of protein functions

Ojida, A., Miyahara, Y. & Hamachi, I., 1 1 2006, : : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 64, 2, p. 141-150 10 p.

研究成果: ジャーナルへの寄稿記事

Proteins
Labeling
Molecules
Covalent bonds
Proteome
41 引用 (Scopus)

Ratiometric fluorescence detection of a tag fused protein using the dual-emission artificial molecular probe

Honda, K., Nakata, E., Ojida, A. & Hamachi, I., 10 3 2006, : : Chemical Communications. 38, p. 4024-4026 3 p.

研究成果: ジャーナルへの寄稿記事

Molecular Probes
Aspartic Acid
Peptides
Fluorescence
Proteins
2007
64 引用 (Scopus)

Design of a hybrid biosensor for enhanced phosphopeptide recognition based on a phosphoprotein binding domain coupled with a fluorescent chemosensor

Anai, T., Nakata, E., Koshi, Y., Ojida, A. & Hamachi, I., 5 16 2007, : : Journal of the American Chemical Society. 129, 19, p. 6233-6239 7 p.

研究成果: ジャーナルへの寄稿記事

Phosphopeptides
Phosphoproteins
Biosensing Techniques
Biosensors
Fluorescence
80 引用 (Scopus)

Non-enzymatic covalent protein labeling using a reactive tag

Nonaka, H., Tsukiji, S., Ojida, A. & Hamachi, I., 12 26 2007, : : Journal of the American Chemical Society. 129, 51, p. 15777-15779 3 p.

研究成果: ジャーナルへの寄稿記事

Labeling
Proteins
Molecular Probes
Molecular recognition
Peptides
39 引用 (Scopus)

Pyrene excimer-based dual-emission detection of a oligoaspartate tag-fused protein by using a ZnII-DpaTyr probe

Honda, K., Fujishima, S. H., Ojida, A. & Hamachi, I., 8 13 2007, : : ChemBioChem. 8, 12, p. 1370-1372 3 p.

研究成果: ジャーナルへの寄稿記事

Aspartic Acid
Proteins
pyrene
2008
15 引用 (Scopus)

Artificial receptors designed for intracellular delivery of anionic phosphate derivatives

Kohira, T., Honda, K., Ojida, A. & Hamachi, I., 3 25 2008, : : ChemBioChem. 9, 5, p. 698-701 4 p.

研究成果: ジャーナルへの寄稿記事

Organometallic Compounds
Artificial Receptors
Molecular Conformation
Drug Delivery Systems
Fluorescence Microscopy
175 引用 (Scopus)

Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor

Taki, M., Desaki, M., Ojida, A., Iyoshi, S., Hirayama, T., Hamachi, I. & Yamamoto, Y., 9 24 2008, : : Journal of the American Chemical Society. 130, 38, p. 12564-12565 2 p.

研究成果: ジャーナルへの寄稿記事

Optical Imaging
Cadmium
Fluorescence
Imaging techniques
Quantum yield
6 引用 (Scopus)

Real-time off/on-mode fluorescence assay for enzyme reactions involving nucleoside polyphosphates by use of a xanthene Zn II -Dpa chemosensor

Kohira, T., Takashima, I., Nonaka, H., Ojida, A. & Hamachi, I., 12 1 2008, : : Chemistry Letters. 37, 11, p. 1164-1165 2 p.

研究成果: ジャーナルへの寄稿記事

Xanthenes
Polyphosphates
Glycosyltransferases
Nucleosides
Zinc
230 引用 (Scopus)

Turn-on fluorescence sensing of nucleoside polyphosphates using a xanthene-based Zn(II) complex chemosensor

Ojida, A., Takashima, I., Kohira, T., Nonaka, H. & Hamachi, I., 9 10 2008, : : Journal of the American Chemical Society. 130, 36, p. 12095-12101 7 p.

研究成果: ジャーナルへの寄稿記事

Xanthenes
Polyphosphates
Nucleosides
Fluorescence
Adenosinetriphosphate
2009
13 引用 (Scopus)

FLAG-tag selective covalent protein labeling via a binding-induced acyl-transfer reaction

Nonaka, H., Fujishima, S. H., Uchinomiya, S., Ojida, A. & Hamachi, I., 12 1 2009, : : Bioorganic and Medicinal Chemistry Letters. 19, 23, p. 6696-6699 4 p.

研究成果: ジャーナルへの寄稿記事

Labeling
Proteins
FLAG peptide
122 引用 (Scopus)

Fluorescent BODIPY-based Zn(II) complex as a molecular probe for selective detection of neurofibrillary tangles in the brains of alzheimer's disease patients

Ojida, A., Sakamoto, T., Inoue, M. A., Fujishima, S. H., Lippens, G. & Hamachi, I., 5 13 2009, : : Journal of the American Chemical Society. 131, 18, p. 6543-6548 6 p.

研究成果: ジャーナルへの寄稿記事

Molecular Probes
tau Proteins
Neurofibrillary Tangles
Brain Diseases
Brain
191 引用 (Scopus)

Molecular recognition, fluorescence sensing, and biological assay of phosphate anion derivatives using artificial Zn(II)-Dpa complexes

Sakamoto, T., Ojida, A. & Hamachi, I., 1 5 2009, : : Chemical Communications. 2, p. 141-152 12 p.

研究成果: ジャーナルへの寄稿記事

Molecular recognition
Anions
Assays
Phosphates
Negative ions
7 引用 (Scopus)

Real-time fluorescence monitoring of GSK3β-catalyzed phosphoryation by use of a BODIPY-based Zn(II)-Dpa chemosensor

Sakamoto, T., Inoue, M. A., Ojida, A. & Hamachi, I., 8 1 2009, : : Bioorganic and Medicinal Chemistry Letters. 19, 15, p. 4175-4177 3 p.

研究成果: ジャーナルへの寄稿記事

Fluorescence
Phosphorylation
Monitoring
Assays
Phosphotransferases
255 引用 (Scopus)

Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T., Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi, T., Sato, Y., Sato, C. および2人, Hamachi, I. & Mori, Y., 3 31 2009, : : Proceedings of the National Academy of Sciences of the United States of America. 106, 13, p. 5400-5405 6 p.

研究成果: ジャーナルへの寄稿記事

Cardiomegaly
Type C Phospholipases
B-Lymphocytes
Cell Membrane
NFATC Transcription Factors
26 引用 (Scopus)

Sequence selective dual-emission detection of (i, i + 1) bis-phosphorylated peptide using diazastilbene-type Zn(ii)-Dpa chemosensor

Ishida, Y., Inoue, M. A., Inoue, T., Ojida, A. & Hamachi, I., 6 23 2009, : : Chemical Communications. 20, p. 2848-2850 3 p.

研究成果: ジャーナルへの寄稿記事

Peptides
Fluorescence
2,2'-dipicolylamine
44 引用 (Scopus)

Site-specific covalent labeling of His-tag fused proteins with a reactive Ni(ii)-NTA probe

Uchinomiya, S., Nonaka, H., Fujishima, S. H., Tsukiji, S., Ojida, A. & Hamachi, I., 10 12 2009, : : Chemical Communications. 39, p. 5880-5882 3 p.

研究成果: ジャーナルへの寄稿記事

Labeling
Proteins
Histidine
2010
17 引用 (Scopus)

Binuclear Ni II -DpaTyr complex as a high affinity probe for an oligo-aspartate tag tethered to proteins

Ojida, A., Fujishima, S. H., Honda, K., Nonaka, H., Uchinomiya, S. & Hamachi, I., 4 1 2010, : : Chemistry - An Asian Journal. 5, 4, p. 877-886 10 p.

研究成果: ジャーナルへの寄稿記事

Aspartic Acid
Peptides
Coordination Complexes
Chromophore-Assisted Light Inactivation
Proteins
147 引用 (Scopus)

Development of highly sensitive fluorescent probes for detection of intracellular copper(I) in living systems

Taki, M., Iyoshi, S., Ojida, A., Hamachi, I. & Yamamoto, Y., 5 5 2010, : : Journal of the American Chemical Society. 132, 17, p. 5938-5939 2 p.

研究成果: ジャーナルへの寄稿記事

Fluorescent Dyes
Copper
Fluorescein
Reaction products
Ether
180 引用 (Scopus)

Rational design of FRET-based ratiometric chemosensors for in vitro and in cell fluorescence analyses of nucleoside polyphosphates

Kurishita, Y., Kohira, T., Ojida, A. & Hamachi, I., 9 29 2010, : : Journal of the American Chemical Society. 132, 38, p. 13290-13299 10 p.

研究成果: ジャーナルへの寄稿記事

Polyphosphates
Fluorescence Resonance Energy Transfer
Nucleosides
Fluorescence
Adenosinetriphosphate
64 引用 (Scopus)

Selective covalent labeling of tag-fused GPCR proteins on live cell surface with a synthetic probe for their functional analysis

Nonaka, H., Fujishima, S. H., Uchinomiya, S., Ojida, A. & Hamachi, I., 7 14 2010, : : Journal of the American Chemical Society. 132, 27, p. 9301-9309 9 p.

研究成果: ジャーナルへの寄稿記事

Functional analysis
Biotin
G-Protein-Coupled Receptors
Labeling
Proteins
7 引用 (Scopus)

Thermoresponsive fluorescent sensor based on core/shell nanocomposite composed of gold nanoparticles and poly(N-isopropylacrylamide)

Wongkongkatep, J., Ladadat, R., Lappermpunsap, W., Wongkongkatep, P., Phinyocheep, P., Ojida, A. & Hamachi, I., 2010, : : Chemistry Letters. 39, 3, p. 184-185 2 p.

研究成果: ジャーナルへの寄稿記事

Gold
Nanocomposites
Fluorescence
Nanoparticles
Sensors
2011
11 引用 (Scopus)

17,20-Lyase inhibitors. Part 4: Design, synthesis and structure-activity relationships of naphthylmethylimidazole derivatives as novel 17,20-lyase inhibitors

Kaku, T., Matsunaga, N., Ojida, A., Tanaka, T., Hara, T., Yamaoka, M., Kusaka, M. & Tasaka, A., 3 1 2011, : : Bioorganic and Medicinal Chemistry. 19, 5, p. 1751-1770 20 p.

研究成果: ジャーナルへの寄稿記事

Steroid 17-alpha-Hydroxylase
Structure-Activity Relationship
Derivatives
Cytochrome P-450 CYP3A
Human Activities
101 引用 (Scopus)

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

Kaku, T., Hitaka, T., Ojida, A., Matsunaga, N., Adachi, M., Tanaka, T., Hara, T., Yamaoka, M., Kusaka, M., Okuda, T., Asahi, S., Furuya, S. & Tasaka, A., 11 1 2011, : : Bioorganic and Medicinal Chemistry. 19, 21, p. 6383-6399 17 p.

研究成果: ジャーナルへの寄稿記事

Steroid 17-alpha-Hydroxylase
Prostatic Neoplasms
Derivatives
Phase III Clinical Trials
Dehydroepiandrosterone
31 引用 (Scopus)

Rigid luminescent bis-zinc(II)-bis-cyclen complexes for the detection of phosphate anions and non-covalent protein labeling in aqueous solution

Bhuyan, M., Katayev, E., Stadlbauer, S., Nonaka, H., Ojida, A., Hamachi, I. & König, B., 5 1 2011, : : European Journal of Organic Chemistry. 15, p. 2807-2817 11 p.

研究成果: ジャーナルへの寄稿記事

Labeling
marking
Anions
Zinc
phosphates
2012

Challenges for Futuristic Nanomedical Detection, Diagnosis and Treatment

Ojida, A. & Kato, M., 1 1 2012, : : Yakugaku Zasshi. 132, 2, 1 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Design of a multinuclear Zn(ii) complex as a new molecular probe for fluorescence imaging of His-tag fused proteins

Fujishima, S. H., Nonaka, H., Uchinomiya, S., Kawase, Y. A., Ojida, A. & Hamachi, I., 1 14 2012, : : Chemical Communications. 48, 4, p. 594-596 3 p.

研究成果: ジャーナルへの寄稿記事

Molecular Probes
G-Protein-Coupled Receptors
Fluorescent Dyes
Histidine
Fluorescence