年単位の研究成果
研究成果 1993 2019
17,20-Lyase inhibitors. Part 4: Design, synthesis and structure-activity relationships of naphthylmethylimidazole derivatives as novel 17,20-lyase inhibitors
Kaku, T., Matsunaga, N., Ojida, A., Tanaka, T., Hara, T., Yamaoka, M., Kusaka, M. & Tasaka, A., 3 1 2011, : : Bioorganic and Medicinal Chemistry. 19, 5, p. 1751-1770 20 p.研究成果: ジャーナルへの寄稿 › 記事
A host-guest system based on collagen-like triple-helix hybridization
Delsuc, N., Uchinomiya, S., Ojida, A. & Hamachi, I., 1 1 2017, : : Chemical Communications. 53, 51, p. 6856-6859 4 p.研究成果: ジャーナルへの寄稿 › 記事
Artificial receptors designed for intracellular delivery of anionic phosphate derivatives
Kohira, T., Honda, K., Ojida, A. & Hamachi, I., 3 25 2008, : : ChemBioChem. 9, 5, p. 698-701 4 p.研究成果: ジャーナルへの寄稿 › 記事
Aza-crown-ether-appended xanthene: Selective ratiometric fluorescent probe for silver(I) ion based on arene-metal ion interaction
Takashima, I., Kanegae, A., Sugimoto, M. & Ojida, A., 7 21 2014, : : Inorganic Chemistry. 53, 14, p. 7080-7082 3 p.研究成果: ジャーナルへの寄稿 › 記事
Binuclear Ni II -DpaTyr complex as a high affinity probe for an oligo-aspartate tag tethered to proteins
Ojida, A., Fujishima, S. H., Honda, K., Nonaka, H., Uchinomiya, S. & Hamachi, I., 4 1 2010, : : Chemistry - An Asian Journal. 5, 4, p. 877-886 10 p.研究成果: ジャーナルへの寄稿 › 記事
Bis(Dpa-Zn II ) appended xanthone: Excitation ratiometric chemosensor for phosphate anions
Ojida, A., Nonaka, H., Miyahara, Y., Tamaru, S. I., Sada, K. & Hamachi, I., 8 18 2006, : : Angewandte Chemie - International Edition. 45, 33, p. 5518-5521 4 p.研究成果: ジャーナルへの寄稿 › 記事
C17,20-lyase inhibitors. Part 2: Design, synthesis and structure-activity relationships of (2-naphthylmethyl)-1H-imidazoles as novel C17,20-lyase inhibitors
Matsunaga, N., Kaku, T., Ojida, A., Tanaka, T., Hara, T., Yamaoka, M., Kusaka, M. & Tasaka, A., 8 15 2004, : : Bioorganic and Medicinal Chemistry. 12, 16, p. 4313-4336 24 p.研究成果: ジャーナルへの寄稿 › 記事
Cell Surface-Anchored Fluorescent Probe Capable of Real-Time Imaging of Single Mast Cell Degranulation Based on Histamine-Induced Coordination Displacement
Oshikawa, Y., Furuta, K., Tanaka, S. & Ojida, A., 2 2 2016, : : Analytical chemistry. 88, 3, p. 1526-1529 4 p.研究成果: ジャーナルへの寄稿 › 記事
Challenges for Futuristic Nanomedical Detection, Diagnosis and Treatment
Ojida, A. & Kato, M., 1 1 2012, : : Yakugaku Zasshi. 132, 2, 1 p.研究成果: ジャーナルへの寄稿 › 記事
Coordination ligand exchange of a xanthene probe-Ce(iii) complex for selective fluorescence sensing of inorganic pyrophosphate
Kittiloespaisan, E., Takashima, I., Kiatpathomchai, W., Wongkongkatep, J. & Ojida, A., 2 28 2014, : : Chemical Communications. 50, 17, p. 2126-2128 3 p.研究成果: ジャーナルへの寄稿 › 記事
Cross-linking strategy for molecular recognition and fluorescent sensing of a multi-phosphorylated peptide in aqueous solution
Ojida, A., Inoue, M. A., Mito-oka, Y. & Hamachi, I., 8 27 2003, : : Journal of the American Chemical Society. 125, 34, p. 10184-10185 2 p.研究成果: ジャーナルへの寄稿 › 記事
Design and synthesis of a novel pre-column derivatization reagent with a 6-methoxy-4-quinolone moiety for fluorescence and tandem mass spectrometric detection and its application to chiral amino acid analysis
Oyama, T., Negishi, E., Onigahara, H., Kusano, N., Miyoshi, Y., Mita, M., Nakazono, M., Ohtsuki, S., Ojida, A., Lindner, W. & Hamase, K., 12 10 2015, : : Journal of Pharmaceutical and Biomedical Analysis. 116, p. 71-79 9 p.研究成果: ジャーナルへの寄稿 › 記事
Design and synthesis of bis(Zn(II)-dipicolylamine)-based fluorescent artificial chemosensors for phosphorylated proteins/peptides
Ojida, A. & Hamachi, I., 11 7 2006, : : Bulletin of the Chemical Society of Japan. 79, 1, p. 35-46 12 p.研究成果: ジャーナルへの寄稿 › 記事
Design of a binuclear Ni(II)-iminodiacetic acid (IDA) complex for selective recognition and covalent labeling of His-tag fused proteins
Takahira, I., Fuchida, H., Tabata, S., Shindo, N., Uchinomiya, S., Hamachi, I. & Ojida, A., 7 1 2014, : : Bioorganic and Medicinal Chemistry Letters. 24, 13, p. 2855-2858 4 p.研究成果: ジャーナルへの寄稿 › 記事
Design of a hybrid biosensor for enhanced phosphopeptide recognition based on a phosphoprotein binding domain coupled with a fluorescent chemosensor
Anai, T., Nakata, E., Koshi, Y., Ojida, A. & Hamachi, I., 5 16 2007, : : Journal of the American Chemical Society. 129, 19, p. 6233-6239 7 p.研究成果: ジャーナルへの寄稿 › 記事
Design of a multinuclear Zn(ii) complex as a new molecular probe for fluorescence imaging of His-tag fused proteins
Fujishima, S. H., Nonaka, H., Uchinomiya, S., Kawase, Y. A., Ojida, A. & Hamachi, I., 1 14 2012, : : Chemical Communications. 48, 4, p. 594-596 3 p.研究成果: ジャーナルへの寄稿 › 記事
Design of coordination interaction of Zn(II) complex with oligo-aspartate peptide to afford a high-affinity tag-probe pair
Fuchida, H., Tabata, S., Shindo, N., Takashima, I., Leng, Q., Hatsuyama, Y., Hamachi, I. & Ojida, A., 1 1 2015, : : Bulletin of the Chemical Society of Japan. 88, 6, p. 784-791 8 p.研究成果: ジャーナルへの寄稿 › 記事
Design of dual-emission chemosensors for ratiometric detection of ATP derivatives
Ojida, A., Miyahara, Y., Wongkongkatep, J., Tamaru, S. I., Sada, K. & Hamachi, I., 11 9 2006, : : Chemistry - An Asian Journal. 1, 4, p. 555-563 9 p.研究成果: ジャーナルへの寄稿 › 記事
Design of ratiometric fluorescent probes based on arene-metal-ion interactions and their application to CdII and hydrogen sulfide imaging in living cells
Takashima, I., Kinoshita, M., Kawagoe, R., Nakagawa, S., Sugimoto, M., Hamachi, I. & Ojida, A., 2 17 2014, : : Chemistry - A European Journal. 20, 8, p. 2184-2192 9 p.研究成果: ジャーナルへの寄稿 › 記事
Development of an AND logic-gate-type fluorescent probe for ratiometric imaging of autolysosome in cell autophagy
Takashima, I., Kawagoe, R., Hamachi, I. & Ojida, A., 1 26 2015, : : Chemistry - A European Journal. 21, 5, p. 2038-2044 7 p.研究成果: ジャーナルへの寄稿 › 記事
Development of highly sensitive fluorescent probes for detection of intracellular copper(I) in living systems
Taki, M., Iyoshi, S., Ojida, A., Hamachi, I. & Yamamoto, Y., 5 5 2010, : : Journal of the American Chemical Society. 132, 17, p. 5938-5939 2 p.研究成果: ジャーナルへの寄稿 › 記事
Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation
Kurashige, N., Fuchida, H., Tabata, S., Uchinomiya, S. & Ojida, A., 4 18 2017, (受理済み/印刷中) : : Bioorganic and Medicinal Chemistry Letters.研究成果: ジャーナルへの寄稿 › 記事
Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer
Kaku, T., Hitaka, T., Ojida, A., Matsunaga, N., Adachi, M., Tanaka, T., Hara, T., Yamaoka, M., Kusaka, M., Okuda, T., Asahi, S., Furuya, S. & Tasaka, A., 11 1 2011, : : Bioorganic and Medicinal Chemistry. 19, 21, p. 6383-6399 17 p.研究成果: ジャーナルへの寄稿 › 記事
Effective disruption of phosphoprotein-protein surface interaction using Zn(II) dipicolylamine-based artificial receptors via two-point interaction
Ojida, A., Inoue, M. A., Mito-Oka, Y., Tsutsumi, H., Sada, K. & Hamachi, I., 2 15 2006, : : Journal of the American Chemical Society. 128, 6, p. 2052-2058 7 p.研究成果: ジャーナルへの寄稿 › 記事
Efficient fluorescent ATP-sensing based on coordination chemistry under aqueous neutral conditions
Ojida, A., Park, S. K., Mito-Oka, Y. & Hamachi, I., 8 26 2002, : : Tetrahedron Letters. 43, 35, p. 6193-6195 3 p.研究成果: ジャーナルへの寄稿 › 記事
First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution
Ojida, A., Mito-Oka, Y., Inoue, M. A. & Hamachi, I., 6 5 2002, : : Journal of the American Chemical Society. 124, 22, p. 6256-6258 3 p.研究成果: ジャーナルへの寄稿 › 記事
FLAG-tag selective covalent protein labeling via a binding-induced acyl-transfer reaction
Nonaka, H., Fujishima, S. H., Uchinomiya, S., Ojida, A. & Hamachi, I., 12 1 2009, : : Bioorganic and Medicinal Chemistry Letters. 19, 23, p. 6696-6699 4 p.研究成果: ジャーナルへの寄稿 › 記事
Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor
Taki, M., Desaki, M., Ojida, A., Iyoshi, S., Hirayama, T., Hamachi, I. & Yamamoto, Y., 9 24 2008, : : Journal of the American Chemical Society. 130, 38, p. 12564-12565 2 p.研究成果: ジャーナルへの寄稿 › 記事
Fluorescent BODIPY-based Zn(II) complex as a molecular probe for selective detection of neurofibrillary tangles in the brains of alzheimer's disease patients
Ojida, A., Sakamoto, T., Inoue, M. A., Fujishima, S. H., Lippens, G. & Hamachi, I., 5 13 2009, : : Journal of the American Chemical Society. 131, 18, p. 6543-6548 6 p.研究成果: ジャーナルへの寄稿 › 記事
Furannulation Strategy for Synthesis of the Naturally Occurring Fused 3-Methylfurans: Efficient Synthesis of Evodone and Menthofuran and Regioselective Synthesis of Maturone via a Lewis Acid Catalyzed Diels-Alder Reaction. Some Comments for Its Mechanistic Aspects
Aso, M., Ojida, A., Yang, G., Cha, O. J., Osawa, E. & Kanematsu, K., 1 1 1993, : : Journal of Organic Chemistry. 58, 15, p. 3960-3968 9 p.研究成果: ジャーナルへの寄稿 › 記事
Highly Enantioselective Reformatsky Reaction of Ketones: Chelation-Assisted Enantioface Discrimination
Ojida, A., Yamano, T., Taya, N. & Tasaka, A., 9 5 2002, : : Organic Letters. 4, 18, p. 3051-3054 4 p.研究成果: ジャーナルへの寄稿 › 記事
Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence
Nishimura, A., Shimauchi, T., Tanaka, T., Shimoda, K., Toyama, T., Kitajima, N., Ishikawa, T., Shindo, N., Numaga-Tomita, T., Yasuda, S., Sato, Y., Kuwahara, K., Kumagai, Y., Akaike, T., Ide, T., Ojida, A., Mori, Y. & Nishida, M., 11 13 2018, : : Science Signaling. 11, 556, eaat5185.研究成果: ジャーナルへの寄稿 › 記事
Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure
Tamamura, H., Ojida, A., Ogawa, T., Tsutsumi, H., Masuno, H., Nakashima, H., Yamamoto, N., Hamachi, I. & Fujii, N., 6 1 2006, : : Journal of Medicinal Chemistry. 49, 11, p. 3412-3415 4 p.研究成果: ジャーナルへの寄稿 › 記事
In-cell covalent labeling of reactive His-tag fused proteins
Uchinomiya, S., Nonaka, H., Wakayama, S., Ojida, A. & Hamachi, I., 6 4 2013, : : Chemical Communications. 49, 44, p. 5022-5024 3 p.研究成果: ジャーナルへの寄稿 › 記事
Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease
Naoya, M., Ikeda, E., Kakimoto, K., Watanabe, M., Shindo, N., Tsuruta, A., Ikeyama, H., Hamamura, K., Higashi, K., Yamashita, T., Kondo, H., Yoshida, Y., Matsuda, M., Ogino, T., Tokushige, K., Itcho, K., Furuichi, Y., Nakao, T., Yasuda, K., Doi, A. および7人, , 11 1 2016, : : EBioMedicine. 13, p. 262-273 12 p.研究成果: ジャーナルへの寄稿 › 記事
Internal-Edge-Substituted Coumarin-Fused [6]Helicenes: Asymmetric Synthesis, Structural Features, and Control of Self-Assembly
Usui, K., Yamamoto, K., Ueno, Y., Igawa, K., Hagihara, R., Masuda, T., Ojida, A., Karasawa, S., Tomooka, K., Hirai, G. & Suemune, H., 10 1 2018, : : Chemistry - A European Journal. 24, 55, p. 14617-14621 5 p.研究成果: ジャーナルへの寄稿 › 記事
Intracellular delivery of chemical probes using a glutathione-responsive traceless tag
Aoyama, E., Fuchida, H., Oshikawa, Y., Uchinomiya, S. & Ojida, A., 1 1 2016, : : Chemical Communications. 52, 49, p. 7715-7718 4 p.研究成果: ジャーナルへの寄稿 › 記事
Label-free, real-time glycosyltransferase assay based on a fluorescent artificial chemosensor
Wongkongkatep, J., Miyahara, Y., Ojida, A. & Hamachi, I., 1 16 2006, : : Angewandte Chemie - International Edition. 45, 4, p. 665-668 4 p.研究成果: ジャーナルへの寄稿 › 記事
Label-free fluorescent detection of loop-mediated isothermal amplification of nucleic acid using pyrophosphate-selective xanthene-based Zn(II)-coordination chemosensor
Kittiloespaisan, E., Ojida, A., Hamachi, I., Seetang-Nun, Y., Kiatpathomchai, W. & Wongkongkatep, J., 2012, : : Chemistry Letters. 41, 12, p. 1666-1668 3 p.研究成果: ジャーナルへの寄稿 › 記事
Ligand-directed acyl imidazole chemistry for labeling of membrane-bound proteins on live cells
Fujishima, S. H., Yasui, R., Miki, T., Ojida, A. & Hamachi, I., 3 7 2012, : : Journal of the American Chemical Society. 134, 9, p. 3961-3964 4 p.研究成果: ジャーナルへの寄稿 › 記事
Molecular recognition, fluorescence sensing, and biological assay of phosphate anion derivatives using artificial Zn(II)-Dpa complexes
Sakamoto, T., Ojida, A. & Hamachi, I., 1 5 2009, : : Chemical Communications. 2, p. 141-152 12 p.研究成果: ジャーナルへの寄稿 › 記事
Molecular Recognition and Fluorescence Sensing of Monophosphorylated Peptides in Aqueous Solution by Bis(zinc(II)-dipicolylamine)-Based Artificial Receptors
Ojida, A., Mito-Oka, Y., Sada, K. & Hamachi, I., 3 3 2004, : : Journal of the American Chemical Society. 126, 8, p. 2454-2463 10 p.研究成果: ジャーナルへの寄稿 › 記事
Molecular recognition in a supramolecular hydrogel to afford a semi-wet sensor chip
Yoshimura, I., Miyahara, Y., Kasagi, N., Yamane, H., Ojida, A. & Hamachi, I., 10 6 2004, : : Journal of the American Chemical Society. 126, 39, p. 12204-12205 2 p.研究成果: ジャーナルへの寄稿 › 記事
Non-enzymatic covalent protein labeling using a reactive tag
Nonaka, H., Tsukiji, S., Ojida, A. & Hamachi, I., 12 26 2007, : : Journal of the American Chemical Society. 129, 51, p. 15777-15779 3 p.研究成果: ジャーナルへの寄稿 › 記事
Oligo-Asp Tag/Zn(II) complex probe as a new pair for labeling and fluorescence imaging of proteins
Ojida, A., Honda, K., Shinmi, D., Kiyonaka, S., Mori, Y. & Hamachi, I., 8 16 2006, : : Journal of the American Chemical Society. 128, 32, p. 10452-10459 8 p.研究成果: ジャーナルへの寄稿 › 記事
Optimized reaction pair of the Cyshis tag and Ni(II)-Nta probe for highly selective chemical labeling of membrane proteins
Zenmyo, N., Tokumaru, H., Uchinomiya, S., Fuchida, H., Tabata, S., Hamachi, I., Shigemoto, R. & Ojida, A., 1 1 2019, : : Bulletin of the Chemical Society of Japan. 92, 5, p. 995-1000 6 p.研究成果: ジャーナルへの寄稿 › 記事
Organelle-localizable fluorescent chemosensors for site-specific multicolor imaging of nucleoside polyphosphate dynamics in living cells
Kurishita, Y., Kohira, T., Ojida, A. & Hamachi, I., 11 14 2012, : : Journal of the American Chemical Society. 134, 45, p. 18779-18789 11 p.研究成果: ジャーナルへの寄稿 › 記事
Organic chemistry for creation and regulation of protein functions
Ojida, A., Miyahara, Y. & Hamachi, I., 1 1 2006, : : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 64, 2, p. 141-150 10 p.研究成果: ジャーナルへの寄稿 › 記事
PET-dependent fluorescence sensing of enzyme reactions using the large and tunable pKa shift of aliphatic amines
Oshikawa, Y. & Ojida, A., 12 18 2013, : : Chemical Communications. 49, 97, p. 11373-11375 3 p.研究成果: ジャーナルへの寄稿 › 記事
Phosphoprotein-selective recognition and staining in SDS-PAGE by bis-Zn(II)-dipycolylamine-appended anthracene
Ojida, A., Kohira, T. & Hamachi, I., 8 5 2004, : : Chemistry Letters. 33, 8, p. 1024-1025 2 p.研究成果: ジャーナルへの寄稿 › 記事