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研究成果 1995 2019

  • 1243 引用
  • 22 h指数
  • 67 記事
  • 2
  • 2 評論記事
  • 1 小調査
記事
1 引用 (Scopus)
Dentinogenesis
Mitochondrial Dynamics
Dynamins
Dental Papilla
Odontoblasts
1 引用 (Scopus)

Acetylsalicylic Acid Treatment and Suppressive Regulation of AKT Accelerate Odontogenic Differentiation of Stem Cells from the Apical Papilla

Tanaka, Y., Sonoda, S., Yamaza, H., Murata, S., Nishida, K., Kyumoto, Y., Uehara, N., Nonaka, K., Kukita, T. & Yamaza, T., 5 1 2019, : : Journal of Endodontics. 45, 5, p. 591-598.e6

研究成果: ジャーナルへの寄稿記事

Aspirin
Stem Cells
Tooth Root
NFI Transcription Factors
Small Interfering RNA
17 引用 (Scopus)

Acute stress response in calorie-restricted rats to lipopolysaccharide- induced inflammation

Tsuchiya, T., Higami, Y., Komatsu, T., Tanaka, K., Honda, S., Yamaza, H., Chiba, T., Ayabe, H. & Shimokawa, I., 1 1 2005, : : Mechanisms of Ageing and Development. 126, 5, p. 568-579 12 p.

研究成果: ジャーナルへの寄稿記事

Lipopolysaccharides
Inflammation
Liver
Down-Regulation
Genes
1 引用 (Scopus)

Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome

Pham, T. T. M., Kato, H., Yamaza, H., Masuda, K., Hirofuji, Y., Sato, H., Nguyen, H. T. N., Han, X., Zhang, Y., Taguchi, T. & Nonaka, K., 8 31 2018, : : BMC neurology. 18, 1, 132.

研究成果: ジャーナルへの寄稿記事

Deciduous Tooth
Dopaminergic Neurons
Down Syndrome
Stem Cells
Dopamine
47 引用 (Scopus)

Anti-aging effects of caloric restriction: Involvement of neuroendocrine adaptation by peripheral signaling

Chiba, T., Yamaza, H., Higami, Y. & Shimokawa, I., 11 15 2002, : : Microscopy Research and Technique. 59, 4, p. 317-324 8 p.

研究成果: ジャーナルへの寄稿記事

anti-aging properties
Caloric Restriction
leptin
adipose tissues
adipose tissue
26 引用 (Scopus)

A transgenic dwarf rat model as a tool for the study of calorie restriction and aging

Yamaza, H., Komatsu, T., Chiba, T., Toyama, H., To, K., Higami, Y. & Shimokawa, I., 1 1 2004, : : Experimental Gerontology. 39, 2, p. 269-272 4 p.

研究成果: ジャーナルへの寄稿記事

Transgenic Rats
Rats
Aging of materials
Insulin
Transgenes
2 引用 (Scopus)

Bilirubin reversibly affects cell death and odontogenic capacity in stem cells from human exfoliated deciduous teeth

Yamaza, H., Tomoda, E., Sonoda, S., Nonaka, K., Kukita, T. & Yamaza, T., 7 1 2018, : : Oral Diseases. 24, 5, p. 809-819 11 p.

研究成果: ジャーナルへの寄稿記事

Deciduous Tooth
Bilirubin
Cell Death
Stem Cells
Mitogen-Activated Protein Kinase 3
10 引用 (Scopus)

Calorie restriction initiated at a young age activates the Akt/PKCζ/λ-Glut4 pathway in rat white adipose tissue in an insulin-independent manner

Park, S., Komatsu, T., Hayashi, H., Yamaza, H., Chiba, T., Higami, Y., Kuramoto, K. & Shimokawa, I., 12 1 2008, : : Age. 30, 4, p. 293-302 10 p.

研究成果: ジャーナルへの寄稿記事

White Adipose Tissue
Protein Kinase C
Insulin
Glucose
Facilitative Glucose Transport Proteins
17 引用 (Scopus)

Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle

Park, S., Komatsu, T., Hayashi, H., Yamaza, H., Chiba, T., Higami, Y., Kuramoto, K. & Shimokawa, I., 9 1 2006, : : Experimental Gerontology. 41, 9, p. 837-845 9 p.

研究成果: ジャーナルへの寄稿記事

Muscle
Rats
Skeletal Muscle
Insulin
Glucose
12 引用 (Scopus)

Calorie restriction minimizes activation of insulin signaling in response to glucose: Potential involvement of the growth hormone-insulin-like growth factor 1 axis

Hayashi, H., Yamaza, H., Komatsu, T., Park, S., Chiba, T., Higami, Y., Nagayasu, T. & Shimokawa, I., 9 1 2008, : : Experimental Gerontology. 43, 9, p. 827-832 6 p.

研究成果: ジャーナルへの寄稿記事

Quadriceps Muscle
Somatomedins
Growth Hormone
Rats
Chemical activation
1 引用 (Scopus)

Clinical approach to a suspected case of first branchial arch syndrome

Yamaguchi, N., Nakamura, S., Yamaza, H., Nishigaki, S., Masuda, K., Yanagita, K. I. & Nonaka, K., 1 1 2014, : : Case Reports in Medicine. 2014, 506804.

研究成果: ジャーナルへの寄稿記事

Branchial Region
Cephalometry
Ear
Hearing Loss
Goldenhar Syndrome
4 引用 (Scopus)
Mixed Dentition
Odontogenic Tumors
Bicuspid
Tooth Germ
Tooth
57 引用 (Scopus)

Cryopreserved Dental Pulp Tissues of Exfoliated Deciduous Teeth Is a Feasible Stem Cell Resource for Regenerative Medicine

Ma, L., Makino, Y., Yamaza, H., Akiyama, K., Hoshino, Y., Song, G., Kukita, T., Nonaka, K., Shi, S. & Yamaza, T., 12 14 2012, : : PloS one. 7, 12, e51777.

研究成果: ジャーナルへの寄稿記事

tooth pulp
Dental Pulp
Regenerative Medicine
Deciduous Tooth
Stem cells
25 引用 (Scopus)

Detection of differentially expressed genes in the early developmental stage of the mouse mandible

Yamaza, H., Matsuo, K., Kiyoshima, T., Shigemura, N., Kobayashi, I., Wada, H., Akamime, A. & Sakai, H., 8 2 2001, : : International Journal of Developmental Biology. 45, 4, p. 675-680 6 p.

研究成果: ジャーナルへの寄稿記事

Mandible
Odontogenesis
Tooth Germ
Genes
Tongue
8 引用 (Scopus)

Dihydroorotate dehydrogenase depletion hampers mitochondrial function and osteogenic differentiation in osteoblasts

Fang, J., Yamaza, H., Uchiumi, T., Hoshino, Y., Masuda, K., Hirofuji, Y., Wagener, F. A. D. T. G., Kang, D. & Nonaka, K., 6 1 2016, : : European Journal of Oral Sciences. 124, 3, p. 241-245 5 p.

研究成果: ジャーナルへの寄稿記事

Osteoblasts
Small Interfering RNA
Adenosine Triphosphate
Cell Proliferation
dihydroorotate dehydrogenase
29 引用 (Scopus)

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., 5 20 2013, : : Bioscience reports. 33, 2, p. 217-227 11 p., e00021.

研究成果: ジャーナルへの寄稿記事

Electron Transport
Biosynthesis
G2 Phase Cell Cycle Checkpoints
Native Polyacrylamide Gel Electrophoresis
dihydroorotate dehydrogenase

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., 2013, : : Bioscience Reports. 33, 2

研究成果: ジャーナルへの寄稿記事

Electron Transport
Biosynthesis
G2 Phase Cell Cycle Checkpoints
Native Polyacrylamide Gel Electrophoresis
dihydroorotate dehydrogenase
8 引用 (Scopus)

Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome

Kato, H., Han, X., Yamaza, H., Masuda, K., Hirofuji, Y., Sato, H., Pham, T. T. M., Taguchi, T. & Nonaka, K., 11 4 2017, : : Biochemical and Biophysical Research Communications. 493, 1, p. 207-212 6 p.

研究成果: ジャーナルへの寄稿記事

Leigh Disease
Mitochondrial Diseases
Bone
Health
Bone and Bones
4 引用 (Scopus)

Divergent regulation of adipose tissue metabolism by calorie restriction and inhibition of growth hormone signaling

Park, S., Komatsu, T., Hayashi, H., Trindade, L. S., Yamaza, H., Chiba, T. & Shimokawa, I., 10 1 2009, : : Experimental Gerontology. 44, 10, p. 646-652 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme inhibition
Metabolism
Growth Hormone
Adipose Tissue
Rats
32 引用 (Scopus)

Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver

To, K., Yamaza, H., Komatsu, T., Hayashida, T., Hayashi, H., Toyama, H., Chiba, T., Higami, Y. & Shimokawa, I., 11 1 2007, : : Experimental Gerontology. 42, 11, p. 1063-1071 9 p.

研究成果: ジャーナルへの寄稿記事

AMP-Activated Protein Kinases
Liver
Rats
Down-Regulation
Quadriceps Muscle
1 引用 (Scopus)

Down-regulation of hepatic AMP-activated protein kinase and up-regulation of CREB coactivator CRTC2 for gluconeogenesis under calorie-restricted conditions at a young age

Trindade, L. S., Park, S. J., Komatsu, T., Yamaza, H., Hayashi, H., Mori, R., Chiba, T., Shimokawa, I. & Kuramoto, K., 1 1 2011, : : Acta Medica Nagasakiensia. 55, 2, p. 85-92 8 p.

研究成果: ジャーナルへの寄稿記事

AMP-Activated Protein Kinases
Gluconeogenesis
Up-Regulation
Down-Regulation
Sirolimus
2 引用 (Scopus)

Effect of insulin-like growth factors on lung development in a nitrofen-induced CDH rat model

Esumi, G., Masumoto, K., Teshiba, R., Nagata, K., Kinoshita, Y., Yamaza, H., Nonaka, K. & Taguchi, T., 2 1 2011, : : Pediatric surgery international. 27, 2, p. 187-192 6 p.

研究成果: ジャーナルへの寄稿記事

Somatomedins
Lung
Fetus
Congenital Diaphragmatic Hernias
nitrofen
13 引用 (Scopus)

Effect of leptin on hypothalamic gene expression in calorie-restricted rats

Komatsu, T., Chiba, T., Yamaza, H., To, K., Toyama, H., Higami, Y. & Shimokawa, I., 1 1 2006, : : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 9, p. 890-898 9 p.

研究成果: ジャーナルへの寄稿記事

Leptin
Arcuate Nucleus of Hypothalamus
Gene Expression
Agouti-Related Protein
Neuropeptide Y

Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells

Sato, H., Kato, H., Yamaza, H., Masuda, K., Nguyen, H. T. N., Pham, T. T. M., Han, X., Hirofuji, Y. & Nonaka, K., 1 1 2017, : : BioMed Research International. 2017, 6037159.

研究成果: ジャーナルへの寄稿記事

Chromosomes, Human, Pair 21
Human Chromosomes
Chromosomes
Cells
Trisomy
4 引用 (Scopus)

Exogenous nitric oxide stimulates the odontogenic differentiation of rat dental pulp stem cells

Sonoda, S., Mei, Y. F., Ikiru, A., Danjo, A., Yamaza, H., Hama, S., Nishida, K., Tang, R., Kyumoto, Y., Uehara, N., Kukita, T., Nishimura, F. & Yamaza, T., 12 1 2018, : : Scientific reports. 8, 1, 3419.

研究成果: ジャーナルへの寄稿記事

Dental Pulp
Nitric Oxide
Stem Cells
Odontoblasts
Dentin
6 引用 (Scopus)

Expression of DNase gamma during Fas-independent apoptotic DNA fragmentation in rodent hepatocytes

Higami, Y., Tsuchiya, T., To, K., Chiba, T., Yamaza, H., Shiokawa, D., Tanuma, S. I. & Shimokawa, I., 6 2004, : : Cell and Tissue Research. 316, 3, p. 403-407 5 p.

研究成果: ジャーナルへの寄稿記事

Deoxyribonucleases
DNA Fragmentation
Hepatocytes
Rodentia
DNA
12 引用 (Scopus)

Expression of Set-α during morphogenesis of mouse lower first molar

Yamaza, H., Matsuo, K., Kobayashi, I., Wada, H., Kiyoshima, T., Akhtar, M., Ishibashi, Y., Sakai, T., Akamine, A. & Sakai, H., 12 1 2001, : : Histochemical Journal. 33, 8, p. 437-441 5 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Morphogenesis
Dental Papilla
Ameloblasts
Odontoblasts
1 引用 (Scopus)
Dental Pulp
Oxidative stress
Deciduous Tooth
Stem cells
Folic Acid
46 引用 (Scopus)

FoxO1 is involved in the antineoplastic effect of calorie restriction

Yamaza, H., Komatsu, T., Wakita, S., Kijogi, C., Park, S., Hayashi, H., Chiba, T., Mori, R., Furuyama, T., Mori, N. & Shimokawa, I., 6 1 2010, : : Aging cell. 9, 3, p. 372-382 11 p.

研究成果: ジャーナルへの寄稿記事

Antineoplastic Agents
Oxidative Stress
Genes
Body Weight Changes
Liver
16 引用 (Scopus)

Functional implication of nucleolin in the mouse first molar development

Xie, M., Kobayashi, I., Kiyoshima, T., Yamaza, H., Honda, J. Y., Takahashi, K., Enoki, N., Akamine, A. & Sakai, H., 8 10 2007, : : Journal of Biological Chemistry. 282, 32, p. 23275-23283 9 p.

研究成果: ジャーナルへの寄稿記事

Enamels
Tooth Germ
Dental Enamel
Mandible
Messenger RNA
14 引用 (Scopus)

Glycolytic enzyme Pgk1 is strongly expressed in the developing tooth germ of the mouse lower first molar

Honda, J. Y., Kobayashi, I., Kiyoshima, T., Yamaza, H., Xie, M., Takahashi, K., Enoki, N., Nagata, K., Nakashima, A. & Sakai, H., 4 2008, : : Histology and Histopathology. 23, 4, p. 423-432 10 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Phosphoglycerate Kinase
Glyceraldehyde-3-Phosphate Dehydrogenases
Enzymes
Fluorescent Antibody Technique
20 引用 (Scopus)

Hepatic gene expression profile of lipid metabolism in rats: Impact of caloric restriction and growth hormone/insulin-like growth factor-1 suppression

Higami, Y., Tsuchiya, T., Chiba, T., Yamaza, H., Muraoka, I., Hirose, M., Komatsu, T. & Shimokawa, I., 1 1 2006, : : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 11, p. 1099-1110 12 p.

研究成果: ジャーナルへの寄稿記事

Caloric Restriction
Somatomedins
Lipid Metabolism
Transcriptome
Growth Hormone
14 引用 (Scopus)

Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: Implications for longevity

Chiba, T., Inoue, D., Mizuno, A., Komatsu, T., Fujita, S., Kubota, H., Luisa Tagliaro, M., Park, S., Trindade, L. S., Hayashida, T., Hayashi, H., Yamaza, H., Higami, Y. & Shimokawa, I., 3 1 2009, : : Neurobiology of Aging. 30, 3, p. 474-482 9 p.

研究成果: ジャーナルへの寄稿記事

Insulin Receptor Substrate Proteins
Hypothalamus
Brain
Insulin-Like Growth Factor I
Insulin
7 引用 (Scopus)

Identification of fasting-induced genes in the rat hypothalamus: Relationship with neuroprotection

Chiba, T., Fujita, S., Kubota, H., Inoue, D., Mizuno, A., Komatsu, T., Yamaza, H., Higami, Y. & Shimokawa, I., 1 1 2007, : : Annals of the New York Academy of Sciences. 1119, 1, p. 216-226 11 p.

研究成果: ジャーナルへの寄稿記事

Hypothalamus
Rats
Fasting
Cell Death
Genes
22 引用 (Scopus)

Immune therapeutic potential of stem cells from human supernumerary teeth

Makino, Y., Yamaza, H., Akiyama, K., Ma, L., Hoshino, Y., Nonaka, K., Terada, Y., Kukita, T., Shi, S. & Yamaza, T., 7 1 2013, : : Journal of Dental Research. 92, 7, p. 609-615 7 p.

研究成果: ジャーナルへの寄稿記事

Supernumerary Tooth
Inbred MRL lpr Mouse
Stem Cells
Th17 Cells
Stem Cell Transplantation
1 引用 (Scopus)
Deciduous Tooth
Dopaminergic Neurons
Neurites
Stem cells
Neurons
18 引用 (Scopus)

In situ expression of heat shock proteins, Hsc73, Hsj2 and Hsp86 in the developing tooth germ of mouse lower first molar

Wada, H., Kobayashi, I., Yamaza, H., Matsuo, K., Kiyoshima, T., Akhtar, M., Sakai, T., Koyano, K. & Sakai, H., 3 1 2002, : : Histochemical Journal. 34, 3-4, p. 105-109 5 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Heat-Shock Proteins
Dental Papilla
Dental Enamel
Enamel Organ
12 引用 (Scopus)

Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells

Sonoda, S., Yamaza, H., Ma, L., Tanaka, Y., Tomoda, E., Aijima, R., Nonaka, K., Kukita, T., Shi, S., Nishimura, F. & Yamaza, T., 1 18 2016, : : Scientific reports. 6, 19286.

研究成果: ジャーナルへの寄稿記事

Pulpitis
Dental Pulp
Immunosuppressive Agents
Interferon-gamma
Stem Cells
22 引用 (Scopus)

In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice

Yamaza, T., Alatas, F. S., Yuniartha, R., Yamaza, H., Fujiyoshi, J. K., Yanagi, Y., Yoshimaru, K., Hayashida, M., Matsuura, T., Aijima, R., Ihara, K., Ohga, S., Shi, S., Nonaka, K. & Taguchi, T., 9 10 2015, : : Stem Cell Research and Therapy. 6, 1, 171.

研究成果: ジャーナルへの寄稿記事

Deciduous Tooth
Stem cells
Liver Cirrhosis
Liver
Stem Cells
29 引用 (Scopus)

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: Regulation of plasma adiponectin and leptin

Yamaza, H., Komatsu, T., To, K., Toyama, H., Chiba, T., Higami, Y. & Shimokawa, I., 1 1 2007, : : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 62, 1, p. 27-33 7 p.

研究成果: ジャーナルへの寄稿記事

Caloric Restriction
Adiponectin
Somatomedins
Leptin
Transgenic Rats
25 引用 (Scopus)

Lifespan extension by caloric restriction: An aspect of energy metabolism

Yamaza, H., Chiba, T., Higami, Y. & Shimokawa, I., 11 15 2002, : : Microscopy Research and Technique. 59, 4, p. 325-330 6 p.

研究成果: ジャーナルへの寄稿記事

Caloric Restriction
gluconeogenesis
gene silencing
metabolism
energy metabolism
91 引用 (Scopus)

Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model

Shimokawa, I., Higami, Y., Utsuyama, M., Tuchiya, T., Komatsu, T., Chiba, T. & Yamaza, H., 1 1 2002, : : American Journal of Pathology. 160, 6, p. 2259-2265 7 p.

研究成果: ジャーナルへの寄稿記事

Transgenic Rats
Somatomedins
Life Expectancy
Growth Hormone
Transgenes
93 引用 (Scopus)

Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction.

Shimokawa, I., Higami, Y., Tsuchiya, T., Otani, H., Komatsu, T., Chiba, T. & Yamaza, H., 1 1 2003, : : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 9, p. 1108-1109 2 p.

研究成果: ジャーナルへの寄稿記事

Caloric Restriction
Somatomedins
Life Expectancy
Growth Hormone
Transgenes
26 引用 (Scopus)

Localization of activated caspase-3-positive and apoptotic cells in the developing tooth germ of the mouse lower first molar

Shigemura, N., Kiyoshima, T., Sakai, T., Matsuo, K., Momoi, T., Yamaza, H., Kobayashi, I., Wada, H., Akamine, A. & Sakai, H., 1 1 2001, : : Histochemical Journal. 33, 5, p. 253-258 6 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Caspase 3
Morphogenesis
Tooth
Embryonic Structures
42 引用 (Scopus)

Manipulation of caloric content but not diet composition, attenuates the deficit in learning and memory of senescence-accelerated mouse strain P8

Komatsu, T., Chiba, T., Yamaza, H., Yamashita, K., Shimada, A., Hoshiyama, Y., Henmi, T., Ohtani, H., Higami, Y., de Cabo, R., Ingram, D. K. & Shimokawa, I., 4 1 2008, : : Experimental Gerontology. 43, 4, p. 339-346 8 p.

研究成果: ジャーナルへの寄稿記事

Nutrition
Learning
Diet
Data storage equipment
Chemical analysis
4 引用 (Scopus)
Methyl-CpG-Binding Protein 2
Rett Syndrome
Deciduous Tooth
Dopaminergic Neurons
Stem cells
8 引用 (Scopus)

Mitochondria regulate the differentiation of stem cells from human exfoliated deciduous teeth

Kato, H., Pham, T. T. M., Yamaza, H., Masuda, K., Hirofuji, Y., Han, X., Sato, H., Taguchi, T. & Nonaka, K., 1 1 2017, : : Cell structure and function. 42, 2, p. 105-116 12 p.

研究成果: ジャーナルへの寄稿記事

Carbonyl Cyanide m-Chlorophenyl Hydrazone
Rotenone
Deciduous Tooth
Mitochondria
Stem Cells
12 引用 (Scopus)

Multiple functional involvement of Thymosin beta-4 in tooth germ development

Ookuma, Y. F., Kiyoshima, T., Kobayashi, I., Nagata, K., Wada, H., Fujiwara, H., Yamaza, H., Nonaka, K. & Sakai, H., 2 1 2013, : : Histochemistry and Cell Biology. 139, 2, p. 355-370 16 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Mandible
Oligodeoxyribonucleotides
Epithelial Cells
Sulfur
Leigh Disease
Bezafibrate
Deciduous Tooth
Organelle Biogenesis
Stem cells