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研究成果 1995 2019

  • 1234 引用
  • 22 h指数
  • 67 記事
  • 2
  • 2 評論記事
  • 1 小調査
フィルター
記事
2019
1 引用 (Scopus)

Acetylsalicylic Acid Treatment and Suppressive Regulation of AKT Accelerate Odontogenic Differentiation of Stem Cells from the Apical Papilla

Tanaka, Y., Sonoda, S., Yamaza, H., Murata, S., Nishida, K., Kyumoto, Y., Uehara, N., Nonaka, K., Kukita, T. & Yamaza, T., 5 1 2019, : : Journal of Endodontics. 45, 5, p. 591-598.e6

研究成果: ジャーナルへの寄稿記事

Aspirin
Stem Cells
Tooth Root
NFI Transcription Factors
Small Interfering RNA
1 引用 (Scopus)
Dental Pulp
Oxidative stress
Deciduous Tooth
Stem cells
Folic Acid
Leigh Disease
Bezafibrate
Deciduous Tooth
Organelle Biogenesis
Stem cells
1 引用 (Scopus)
Dental Pulp
Dopaminergic Neurons
Brain-Derived Neurotrophic Factor
Neurites
Attention Deficit Disorder with Hyperactivity
公開
Hepatolenticular Degeneration
Deciduous Tooth
Inbred LEC Rats
Hepatocytes
Stem Cells
2018
1 引用 (Scopus)
Dentinogenesis
Mitochondrial Dynamics
Dynamins
Dental Papilla
Odontoblasts
1 引用 (Scopus)

Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome

Pham, T. T. M., Kato, H., Yamaza, H., Masuda, K., Hirofuji, Y., Sato, H., Nguyen, H. T. N., Han, X., Zhang, Y., Taguchi, T. & Nonaka, K., 8 31 2018, : : BMC neurology. 18, 1, 132.

研究成果: ジャーナルへの寄稿記事

Deciduous Tooth
Dopaminergic Neurons
Down Syndrome
Stem Cells
Dopamine
2 引用 (Scopus)

Bilirubin reversibly affects cell death and odontogenic capacity in stem cells from human exfoliated deciduous teeth

Yamaza, H., Tomoda, E., Sonoda, S., Nonaka, K., Kukita, T. & Yamaza, T., 7 1 2018, : : Oral Diseases. 24, 5, p. 809-819 11 p.

研究成果: ジャーナルへの寄稿記事

Deciduous Tooth
Bilirubin
Cell Death
Stem Cells
Mitogen-Activated Protein Kinase 3
3 引用 (Scopus)

Exogenous nitric oxide stimulates the odontogenic differentiation of rat dental pulp stem cells

Sonoda, S., Mei, Y. F., Ikiru, A., Danjo, A., Yamaza, H., Hama, S., Nishida, K., Tang, R., Kyumoto, Y., Uehara, N., Kukita, T., Nishimura, F. & Yamaza, T., 12 1 2018, : : Scientific reports. 8, 1, 3419.

研究成果: ジャーナルへの寄稿記事

Dental Pulp
Nitric Oxide
Stem Cells
Odontoblasts
Dentin
1 引用 (Scopus)
Deciduous Tooth
Dopaminergic Neurons
Neurites
Stem cells
Neurons
4 引用 (Scopus)
Methyl-CpG-Binding Protein 2
Rett Syndrome
Deciduous Tooth
Dopaminergic Neurons
Stem cells
1 引用 (Scopus)
pamidronate
Hyperbilirubinemia
Deciduous Tooth
Cell death
Stem cells
3 引用 (Scopus)

Suppression of AKT-mTOR signal pathway enhances osteogenic/dentinogenic capacity of stem cells from apical papilla

Tanaka, Y., Sonoda, S., Yamaza, H., Murata, S., Nishida, K., Hama, S., Kyumoto, Y., Uehara, N., Nonaka, K., Kukita, T. & Yamaza, T., 11 29 2018, : : Stem Cell Research and Therapy. 9, 1, 334.

研究成果: ジャーナルへの寄稿記事

Sirolimus
Stem cells
Signal Transduction
Stem Cells
1-Phosphatidylinositol 4-Kinase
2017
8 引用 (Scopus)

Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome

Kato, H., Han, X., Yamaza, H., Masuda, K., Hirofuji, Y., Sato, H., Pham, T. T. M., Taguchi, T. & Nonaka, K., 11 4 2017, : : Biochemical and Biophysical Research Communications. 493, 1, p. 207-212 6 p.

研究成果: ジャーナルへの寄稿記事

Leigh Disease
Mitochondrial Diseases
Bone
Health
Bone and Bones

Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells

Sato, H., Kato, H., Yamaza, H., Masuda, K., Nguyen, H. T. N., Pham, T. T. M., Han, X., Hirofuji, Y. & Nonaka, K., 1 1 2017, : : BioMed Research International. 2017, 6037159.

研究成果: ジャーナルへの寄稿記事

Chromosomes, Human, Pair 21
Human Chromosomes
Chromosomes
Cells
Trisomy
8 引用 (Scopus)

Mitochondria regulate the differentiation of stem cells from human exfoliated deciduous teeth

Kato, H., Pham, T. T. M., Yamaza, H., Masuda, K., Hirofuji, Y., Han, X., Sato, H., Taguchi, T. & Nonaka, K., 1 1 2017, : : Cell structure and function. 42, 2, p. 105-116 12 p.

研究成果: ジャーナルへの寄稿記事

Carbonyl Cyanide m-Chlorophenyl Hydrazone
Rotenone
Deciduous Tooth
Mitochondria
Stem Cells
2016
7 引用 (Scopus)

Dihydroorotate dehydrogenase depletion hampers mitochondrial function and osteogenic differentiation in osteoblasts

Fang, J., Yamaza, H., Uchiumi, T., Hoshino, Y., Masuda, K., Hirofuji, Y., Wagener, F. A. D. T. G., Kang, D. & Nonaka, K., 6 1 2016, : : European Journal of Oral Sciences. 124, 3, p. 241-245 5 p.

研究成果: ジャーナルへの寄稿記事

Osteoblasts
Small Interfering RNA
Adenosine Triphosphate
Cell Proliferation
dihydroorotate dehydrogenase
11 引用 (Scopus)

Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells

Sonoda, S., Yamaza, H., Ma, L., Tanaka, Y., Tomoda, E., Aijima, R., Nonaka, K., Kukita, T., Shi, S., Nishimura, F. & Yamaza, T., 1 18 2016, : : Scientific reports. 6, 19286.

研究成果: ジャーナルへの寄稿記事

Pulpitis
Dental Pulp
Immunosuppressive Agents
Interferon-gamma
Stem Cells
2015
4 引用 (Scopus)
Mixed Dentition
Odontogenic Tumors
Bicuspid
Tooth Germ
Tooth
21 引用 (Scopus)

In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice

Yamaza, T., Alatas, F. S., Yuniartha, R., Yamaza, H., Fujiyoshi, J., Yanagi, Y., Yoshimaru, K., Hayashida, M., Matsuura, T., Aijima, R., Ihara, K., Ohga, S., Shi, S., Nonaka, K. & Taguchi, T., 9 10 2015, : : Stem Cell Research and Therapy. 6, 1, 171.

研究成果: ジャーナルへの寄稿記事

Deciduous Tooth
Stem cells
Liver Cirrhosis
Liver
Stem Cells

Overexpression of the adiponectin gene mimics the metabolic and stress resistance effects of calorie restriction, but not the anti-tumor effect

Kamohara, R., Yamaza, H., Tsuchiya, T., Komatsu, T., Park, S., Hayashi, H., Chiba, T., Mori, R., Otabe, S., Yamada, K., Nagayasu, T. & Shimokawa, I., 4 1 2015, : : Experimental Gerontology. 64, p. 46-54 9 p.

研究成果: ジャーナルへの寄稿記事

Physiological Stress
Adiponectin
Nutrition
Tumors
Genes
32 引用 (Scopus)

The life-extending effect of dietary restriction requires Foxo3 in mice

Shimokawa, I., Komatsu, T., Hayashi, N., Kim, S. E., Kawata, T., Park, S., Hayashi, H., Yamaza, H., Chiba, T. & Mori, R., 8 1 2015, : : Aging cell. 14, 4, p. 707-709 3 p.

研究成果: ジャーナルへの寄稿記事

Neoplasms
Forkhead Transcription Factors
22 引用 (Scopus)

Transplantation of mesenchymal stem cells ameliorates secondary osteoporosis through interleukin-17-impaired functions of recipient bone marrow mesenchymal stem cells in MRL/lpr mice

Ma, L., Aijima, R., Hoshino, Y., Yamaza, H., Tomoda, E., Tanaka, Y., Sonoda, S., Song, G., Zhao, W., Nonaka, K., Shi, S. & Yamaza, T., 5 27 2015, : : Stem Cell Research and Therapy. 6, 1, 104.

研究成果: ジャーナルへの寄稿記事

Inbred MRL lpr Mouse
Mesenchymal Stem Cell Transplantation
Interleukin-17
Stem cells
Mesenchymal Stromal Cells
2014
1 引用 (Scopus)

Clinical approach to a suspected case of first branchial arch syndrome

Yamaguchi, N., Nakamura, S., Yamaza, H., Nishigaki, S., Masuda, K., Yanagita, K. I. & Nonaka, K., 1 1 2014, : : Case Reports in Medicine. 2014, 506804.

研究成果: ジャーナルへの寄稿記事

Branchial Region
Cephalometry
Ear
Hearing Loss
Goldenhar Syndrome
2013
29 引用 (Scopus)

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., 5 20 2013, : : Bioscience reports. 33, 2, p. 217-227 11 p., e00021.

研究成果: ジャーナルへの寄稿記事

Electron Transport
Biosynthesis
G2 Phase Cell Cycle Checkpoints
Native Polyacrylamide Gel Electrophoresis
dihydroorotate dehydrogenase

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., 2013, : : Bioscience Reports. 33, 2

研究成果: ジャーナルへの寄稿記事

Electron Transport
Biosynthesis
G2 Phase Cell Cycle Checkpoints
Native Polyacrylamide Gel Electrophoresis
dihydroorotate dehydrogenase
22 引用 (Scopus)

Immune therapeutic potential of stem cells from human supernumerary teeth

Makino, Y., Yamaza, H., Akiyama, K., Ma, L., Hoshino, Y., Nonaka, K., Terada, Y., Kukita, T., Shi, S. & Yamaza, T., 7 1 2013, : : Journal of Dental Research. 92, 7, p. 609-615 7 p.

研究成果: ジャーナルへの寄稿記事

Supernumerary Tooth
Inbred MRL lpr Mouse
Stem Cells
Th17 Cells
Stem Cell Transplantation
12 引用 (Scopus)

Multiple functional involvement of Thymosin beta-4 in tooth germ development

Ookuma, Y. F., Kiyoshima, T., Kobayashi, I., Nagata, K., Wada, H., Fujiwara, H., Yamaza, H., Nonaka, K. & Sakai, H., 2 1 2013, : : Histochemistry and Cell Biology. 139, 2, p. 355-370 16 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Mandible
Oligodeoxyribonucleotides
Epithelial Cells
Sulfur
2012
57 引用 (Scopus)

Cryopreserved Dental Pulp Tissues of Exfoliated Deciduous Teeth Is a Feasible Stem Cell Resource for Regenerative Medicine

Ma, L., Makino, Y., Yamaza, H., Akiyama, K., Hoshino, Y., Song, G., Kukita, T., Nonaka, K., Shi, S. & Yamaza, T., 12 14 2012, : : PLoS One. 7, 12, e51777.

研究成果: ジャーナルへの寄稿記事

tooth pulp
Dental Pulp
Regenerative Medicine
Deciduous Tooth
Stem cells
17 引用 (Scopus)

Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Saito, T., Takazaki, S., Kanki, T., Yamaza, H., Nonaka, K. & Kang, D., 12 1 2012, : : Bioscience reports. 32, 6, p. 631-639 9 p.

研究成果: ジャーナルへの寄稿記事

Defects
Mutation
Protein Stability
Proteins
Mitochondria
2011
1 引用 (Scopus)

Down-regulation of hepatic AMP-activated protein kinase and up-regulation of CREB coactivator CRTC2 for gluconeogenesis under calorie-restricted conditions at a young age

Trindade, L. S., Park, S. J., Komatsu, T., Yamaza, H., Hayashi, H., Mori, R., Chiba, T., Shimokawa, I. & Kuramoto, K., 1 1 2011, : : Acta Medica Nagasakiensia. 55, 2, p. 85-92 8 p.

研究成果: ジャーナルへの寄稿記事

AMP-Activated Protein Kinases
Gluconeogenesis
Up-Regulation
Down-Regulation
Sirolimus
2 引用 (Scopus)

Effect of insulin-like growth factors on lung development in a nitrofen-induced CDH rat model

Esumi, G., Masumoto, K., Teshiba, R., Nagata, K., Kinoshita, Y., Yamaza, H., Nonaka, K. & Taguchi, T., 2 1 2011, : : Pediatric surgery international. 27, 2, p. 187-192 6 p.

研究成果: ジャーナルへの寄稿記事

Somatomedins
Lung
Fetus
Congenital Diaphragmatic Hernias
nitrofen
2010
46 引用 (Scopus)

FoxO1 is involved in the antineoplastic effect of calorie restriction

Yamaza, H., Komatsu, T., Wakita, S., Kijogi, C., Park, S., Hayashi, H., Chiba, T., Mori, R., Furuyama, T., Mori, N. & Shimokawa, I., 6 1 2010, : : Aging cell. 9, 3, p. 372-382 11 p.

研究成果: ジャーナルへの寄稿記事

Antineoplastic Agents
Oxidative Stress
Genes
Body Weight Changes
Liver
12 引用 (Scopus)

Protogenin, a new member of the immunoglobulin superfamily, is implicated in the development of the mouse lower first molar

Takahashi, K. F., Kiyoshima, T., Kobayashi, I., Xie, M., Yamaza, H., Fujiwara, H., Ookuma, Y., Nagata, K., Wada, H., Sakai, T., Terada, Y. & Sakai, H., 11 29 2010, : : BMC Developmental Biology. 10, 115.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Mandible
Immunoglobulins
Epithelial Cells
Oligodeoxyribonucleotides
29 引用 (Scopus)

SIRT1 regulates thyroid-stimulating hormone release by enhancing PIP5Kγ activity through deacetylation of specific lysine residues in mammals

Akieda-Asai, S., Zaima, N., Ikegami, K., Kahyo, T., Yao, I., Hatanaka, T., Iemura, S. I., Sugiyama, R., Yokozeki, T., Eishi, Y., Koike, M., Ikeda, K., Chiba, T., Yamaza, H., Shimokawa, I., Song, S. Y., Matsuno, A., Mizutani, A., Sawabe, M., Chao, M. V. および8人, Tanaka, M., Kanaho, Y., Natsume, T., Sugimura, H., Date, Y., Mcburney, M. W., Guarente, L. & Setou, M., 8 16 2010, : : PloS one. 5, 7, e11755.

研究成果: ジャーナルへの寄稿記事

thyrotropin
Mammals
phosphatidylinositols
Thyrotropin
Metabolism
2009
4 引用 (Scopus)

Divergent regulation of adipose tissue metabolism by calorie restriction and inhibition of growth hormone signaling

Park, S., Komatsu, T., Hayashi, H., Trindade, L. S., Yamaza, H., Chiba, T. & Shimokawa, I., 10 1 2009, : : Experimental Gerontology. 44, 10, p. 646-652 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme inhibition
Metabolism
Growth Hormone
Adipose Tissue
Rats
14 引用 (Scopus)

Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: Implications for longevity

Chiba, T., Inoue, D., Mizuno, A., Komatsu, T., Fujita, S., Kubota, H., Luisa Tagliaro, M., Park, S., Trindade, L. S., Hayashida, T., Hayashi, H., Yamaza, H., Higami, Y. & Shimokawa, I., 3 1 2009, : : Neurobiology of Aging. 30, 3, p. 474-482 9 p.

研究成果: ジャーナルへの寄稿記事

Insulin Receptor Substrate Proteins
Hypothalamus
Brain
Insulin-Like Growth Factor I
Insulin
22 引用 (Scopus)

Similar metabolic responses to calorie restriction in lean and obese Zucker rats

Chiba, T., Komatsu, T., Nakayama, M., Adachi, T., Tamashiro, Y., Hayashi, H., Yamaza, H., Higami, Y. & Shimokawa, I., 10 15 2009, : : Molecular and Cellular Endocrinology. 309, 1-2, p. 17-25 9 p.

研究成果: ジャーナルへの寄稿記事

Zucker Rats
Rats
Insulin
Neuropeptide Y
Insulin Resistance
2008
10 引用 (Scopus)

Calorie restriction initiated at a young age activates the Akt/PKCζ/λ-Glut4 pathway in rat white adipose tissue in an insulin-independent manner

Park, S., Komatsu, T., Hayashi, H., Yamaza, H., Chiba, T., Higami, Y., Kuramoto, K. & Shimokawa, I., 12 1 2008, : : Age. 30, 4, p. 293-302 10 p.

研究成果: ジャーナルへの寄稿記事

White Adipose Tissue
Protein Kinase C
Insulin
Glucose
Facilitative Glucose Transport Proteins
12 引用 (Scopus)

Calorie restriction minimizes activation of insulin signaling in response to glucose: Potential involvement of the growth hormone-insulin-like growth factor 1 axis

Hayashi, H., Yamaza, H., Komatsu, T., Park, S., Chiba, T., Higami, Y., Nagayasu, T. & Shimokawa, I., 9 1 2008, : : Experimental Gerontology. 43, 9, p. 827-832 6 p.

研究成果: ジャーナルへの寄稿記事

Quadriceps Muscle
Somatomedins
Growth Hormone
Rats
Chemical activation
14 引用 (Scopus)

Glycolytic enzyme Pgk1 is strongly expressed in the developing tooth germ of the mouse lower first molar

Honda, J. Y., Kobayashi, I., Kiyoshima, T., Yamaza, H., Xie, M., Takahashi, K., Enoki, N., Nagata, K., Nakashima, A. & Sakai, H., 4 2008, : : Histology and Histopathology. 23, 4, p. 423-432 10 p.

研究成果: ジャーナルへの寄稿記事

Tooth Germ
Phosphoglycerate Kinase
Glyceraldehyde-3-Phosphate Dehydrogenases
Enzymes
Fluorescent Antibody Technique
42 引用 (Scopus)

Manipulation of caloric content but not diet composition, attenuates the deficit in learning and memory of senescence-accelerated mouse strain P8

Komatsu, T., Chiba, T., Yamaza, H., Yamashita, K., Shimada, A., Hoshiyama, Y., Henmi, T., Ohtani, H., Higami, Y., de Cabo, R., Ingram, D. K. & Shimokawa, I., 4 1 2008, : : Experimental Gerontology. 43, 4, p. 339-346 8 p.

研究成果: ジャーナルへの寄稿記事

Nutrition
Learning
Diet
Data storage equipment
Chemical analysis
21 引用 (Scopus)

Pituitary growth hormone suppression reduces resistin expression and enhances insulin effectiveness: Relationship with caloric restriction

Chiba, T., Yamaza, H., Komatsu, T., Nakayama, M., Fujita, S., Hayashi, H., Higami, Y. & Shimokawa, I., 6 1 2008, : : Experimental Gerontology. 43, 6, p. 595-600 6 p.

研究成果: ジャーナルへの寄稿記事

Resistin
Caloric Restriction
Growth Hormone
Insulin
Insulin-Like Growth Factor I
2007
32 引用 (Scopus)

Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver

To, K., Yamaza, H., Komatsu, T., Hayashida, T., Hayashi, H., Toyama, H., Chiba, T., Higami, Y. & Shimokawa, I., 11 1 2007, : : Experimental Gerontology. 42, 11, p. 1063-1071 9 p.

研究成果: ジャーナルへの寄稿記事

AMP-Activated Protein Kinases
Liver
Rats
Down-Regulation
Quadriceps Muscle
16 引用 (Scopus)

Functional implication of nucleolin in the mouse first molar development

Xie, M., Kobayashi, I., Kiyoshima, T., Yamaza, H., Honda, J. Y., Takahashi, K., Enoki, N., Akamine, A. & Sakai, H., 8 10 2007, : : Journal of Biological Chemistry. 282, 32, p. 23275-23283 9 p.

研究成果: ジャーナルへの寄稿記事

Enamels
Tooth Germ
Dental Enamel
Mandible
Messenger RNA
7 引用 (Scopus)

Identification of fasting-induced genes in the rat hypothalamus: Relationship with neuroprotection

Chiba, T., Fujita, S., Kubota, H., Inoue, D., Mizuno, A., Komatsu, T., Yamaza, H., Higami, Y. & Shimokawa, I., 1 1 2007, : : Annals of the New York Academy of Sciences. 1119, 1, p. 216-226 11 p.

研究成果: ジャーナルへの寄稿記事

Hypothalamus
Rats
Fasting
Cell Death
Genes
29 引用 (Scopus)

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: Regulation of plasma adiponectin and leptin

Yamaza, H., Komatsu, T., To, K., Toyama, H., Chiba, T., Higami, Y. & Shimokawa, I., 1 1 2007, : : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 62, 1, p. 27-33 7 p.

研究成果: ジャーナルへの寄稿記事

Caloric Restriction
Adiponectin
Somatomedins
Leptin
Transgenic Rats
58 引用 (Scopus)

Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster

Zhan, M., Yamaza, H., Sun, Y., Sinclair, J., Li, H. & Zou, S., 8 9 2007, : : Genome Research. 17, 8, p. 1236-1243 8 p.

研究成果: ジャーナルへの寄稿記事

Drosophila melanogaster
Genes
Biological Phenomena
Nerve Tissue
Invertebrates
2006
17 引用 (Scopus)

Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle

Park, S., Komatsu, T., Hayashi, H., Yamaza, H., Chiba, T., Higami, Y., Kuramoto, K. & Shimokawa, I., 9 1 2006, : : Experimental Gerontology. 41, 9, p. 837-845 9 p.

研究成果: ジャーナルへの寄稿記事

Muscle
Rats
Skeletal Muscle
Insulin
Glucose