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研究成果 1987 2019

1997
8 引用 (Scopus)

Cytokeratin 8 and 19 as antigens recognized by adenocarcinoma-reactive human monoclonal antibody AE6F4

Ichikawa, A., Tachibana, H., Kawamoto, S., Kamei, M., Honjoh, T., Hashizume, S. & Shirahata, S., 12 4 1997, : : Human Antibodies. 8, 4, p. 195-202 8 p.

研究成果: ジャーナルへの寄稿記事

Keratin-8
Keratin-19
Adenocarcinoma
Monoclonal Antibodies
Antigens
1 引用 (Scopus)

Effect of Synthetic Food Colorings on Immunoglobulin Production by Rat Lymphocytes

Kuramoto, Y., Tsuruta, O., Tachibana, H., Sugano, M. & Yamada, K., 12 1 1997, : : Journal of the Faculty of Agriculture, Kyushu University. 42, 1-2, p. 193-201 9 p.

研究成果: ジャーナルへの寄稿記事

imitation foods
food coloring
immunoglobulins
Immunoglobulin E
Immunoglobulins
10 引用 (Scopus)

Enhancing effects of food components on the production of interferon β from animal cells suppressed by stress hormones

Kabayama, S., Osada, K., Tachibana, H., Katakura, Y. & Shirahata, S., 1997, : : Cytotechnology. 23, 1-3, p. 119-125 7 p.

研究成果: ジャーナルへの寄稿記事

Cortisol
Interferons
Hormones
Hydrocortisone
Animals
3 引用 (Scopus)
Hybridomas
Lectins
Cells
Light
Cell Line
2 引用 (Scopus)

Improvement of antigen binding ability of human antibodies by light chain shifting

Siripen, T., Tachibana, H., Katakura, Y. & Shirahata, S., 12 1 1997, : : Cytotechnology. 25, 1-3, p. 155-164 10 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
Antigens
Antibodies
Monoclonal Antibodies
Light
1996
10 引用 (Scopus)

Inducing the loss of immunoglobulin λ light chain production and the rearrangement of a previously excluded allele in human plasma B cell lines with concanavalin A

Tachibana, H., Ushio, Y., Krungkasem, C. & Shirahata, S., 8 5 1996, : : Journal of Biological Chemistry. 271, 29, p. 17404-17410 7 p.

研究成果: ジャーナルへの寄稿記事

Plasma (human)
Immunoglobulin Light Chains
Concanavalin A
Plasma Cells
B-Lymphocytes
8 引用 (Scopus)
Hybridomas
Glycosylation
Light
Antigens
Antibodies
11 引用 (Scopus)

Production of Recombinant Human Monoclonal Antibody Using ras-Amplified BHK-21 Cells in a Protein-free Medium

Inoue, Y., Lopez, L. B., Kawamoto, S., Arita, N., Teruya, K., Seki, K., Shoji, M., Kamei, M., Hashizume, S., Shiozawa, Y., Tachibana, H., Ohashi, H., Yasumoto, K., Nagashima, A., Nakahashi, H., Suzuki, T., Imai, T., Nomoto, K., Takenoyama, M., Katakura, Y. および1人, Shirahata, S., 1 1996, : : Bioscience, Biotechnology and Biochemistry. 60, 5, p. 811-817 7 p.

研究成果: ジャーナルへの寄稿記事

Serum-Free Culture Media
Immunoglobulin G
Monoclonal Antibodies
Cells
Lung Neoplasms
1995
18 引用 (Scopus)

E1A and ras Oncogenes Synergistically Enhance Recombinant Protein Production under Control of the Cytomegalovirus Promoter in BHK-21 Cells

Shirahata, S., Watanabe, J., Teruya, K., Yano, T., Osada, K., Tachibana, H., Murakami, H., Ohashi, H. & Kim, E. H., 1 1 1995, : : Bioscience, biotechnology, and biochemistry. 59, 2, p. 345-347 3 p.

研究成果: ジャーナルへの寄稿記事

ras Genes
Cytomegalovirus
Recombinant Proteins
Interleukin-6
Productivity

Epitope in cytochrome C from Candida krusei cross-reacts lung cancer-specific human monoclonal antibody HB4C5

Kawamoto, S., Hashizume, S., Katakura, Y., Tachibana, H., Shirshata, S. & Murakami, H., 1995, : : In Vitro Cellular and Developmental Biology - Animal. 31, 6, p. 424+426 3 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Epitope in cytochrome C from Candida krusei cross-reacts lung cancer-specific human monoclonal antibody HB4C5

Kawamoto, S., Hashizume, S., Katakura, Y., Tachibana, H., Shirahata, S. & Murakami, H., 1 1 1995, : : In Vitro Cellular & Developmental Biology - Animal: Journal of the Society for In Vitro Biology. 31, 6, p. 424-426 3 p.

研究成果: ジャーナルへの寄稿レター

Molecular Sequence Data
Neoplasm Antibodies
Antibody Specificity
Cytochromes
Cytochromes c
Wheat Germ Agglutinins
Antibody Affinity
Hybridomas
Concanavalin A
Glycosylation
6 引用 (Scopus)

Impaired Tumor Phenotypes in Class II Major Histocompatibility Complex Antigen-Inducible Cells Originated from Human Lung Adenocarcinoma

Kawamoto, S., Inoue, Y., Shinozaki, Y., Katakura, Y., Tachibana, H., Shirahata, S. & Murakami, H., 10 4 1995, : : Biochemical and Biophysical Research Communications. 215, 1, p. 280-285 6 p.

研究成果: ジャーナルへの寄稿記事

Histocompatibility Antigens Class II
Major Histocompatibility Complex
Tumors
Cells
Phenotype
11 引用 (Scopus)

Molecular cloning of the 31 kDa cytosolic phospholipase A2, as an antigen recognized by the lung cancer-specific human monoclonal antibody, AE6F4

Kawamoto, S., Shoji, M., Setoguchi, Y., Kato, M., Hashizume, S., Ichikawa, A., Osada, K., Katakura, Y., Tachibana, H. & Murakami, H., 1 1 1995, : : Cytotechnology. 17, 2, p. 103-108 6 p.

研究成果: ジャーナルへの寄稿記事

Cytosolic Phospholipases A2
Monoclonal antibodies
Cloning
Molecular Cloning
Antigens
3 引用 (Scopus)
Molecular Cloning
Cytochromes
Lung Neoplasms
Yeasts
Monoclonal Antibodies
14 引用 (Scopus)

Ras Amplification in BHK-21 Cells Produces a Host Cell Line for Further Rapid Establishment of Recombinant Protein Hyper-Producing Cell Lines

Teruya, K., Yano, T., Shirahata, S., Watanabe, J., Osada, K., Tachibana, H., Murakami, H., Ohashi, H. & Kim, E. H., 1 1 1995, : : Bioscience, biotechnology, and biochemistry. 59, 2, p. 341-344 4 p.

研究成果: ジャーナルへの寄稿記事

Recombinant Proteins
Amplification
Interleukin-6
Plasmids
Cells
1994
32 引用 (Scopus)

Changes of monosaccharide availability of human hybridoma lead to alteration of biological properties of human monoclonal antibody

Tachibana, H., Taniguchi, K., Ushio, Y., Teruya, K., Osada, K. & Murakami, H., 1 1 1994, : : Cytotechnology. 16, 3, p. 151-157 7 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
Monosaccharides
Hybridomas
Antibodies
Monoclonal Antibodies
10 引用 (Scopus)

Heterogeneous expression of human antibody λ chains by concanavalin A- resistant hybridomas lead to changed antigen binding

Tachibana, H., Kido, I. & Murakami, H., 1 1 1994, : : Journal of Biological Chemistry. 269, 46, p. 29061-29066 6 p.

研究成果: ジャーナルへの寄稿記事

Hybridomas
Concanavalin A
Light
Antigens
Antibodies
23 引用 (Scopus)

Ras oncogene enhances the production of a recombinant protein regulated by the cytomegalovirus promoter in BHK-21 cells

Yano, T., Teruya, K., Shirahata, S., Watanabe, J., Osada, K., Tachibana, H., Ohashi, H., Kim, E. H. & Murakami, H., 1 1 1994, : : Cytotechnology. 16, 3, p. 167-178 12 p.

研究成果: ジャーナルへの寄稿記事

Recombinant proteins
ras Genes
Cytomegalovirus
Oncogenes
Recombinant Proteins
2 引用 (Scopus)
Glycosylation
Oligosaccharides
Light
Antibodies
Carbohydrates
1993
14 引用 (Scopus)

Activity enhancement of a lung cancer–associated human monoclonal antibody HB4C5 by N-deglycosylation

Kato, M., Mochizuki, K., Hashizume, S., Tachibana, H., Shirahata, S. & Murakami, H., 1 1 1993, : : Human Antibodies. 4, 1, p. 9-14 6 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Light
Lung
Antibodies
Antigens
30 引用 (Scopus)

Enhancement of interferon-β production with sphingomyelin from fermented milk

Osada, K., Nagira, K., Teruya, K., Tachibana, H., Shirahata, S. & Murakami, H., 6 1 1993, : : Biotherapy. 7, 2, p. 115-123 9 p.

研究成果: ジャーナルへの寄稿記事

Sphingomyelins
Fast Atom Bombardment Mass Spectrometry
Interferons
Milk
Cerebrosides
2 引用 (Scopus)

Human bifunctional antibody generated by heterologous association of heavy and light chains

Tachibana, H., Shirahata, S. & Murakami, H., 1993, : : Human Antibodies. 4, 2, p. 42-46 5 p.

研究成果: ジャーナルへの寄稿記事

Bispecific Antibodies
Hybridomas
Carboxypeptidases A
Light
Clone Cells
21 引用 (Scopus)

Identification of hybrid-type carbohydrate chains on the light chain of human monoclonal antibody specific to lung adenocarcinoma

Tachibana, H., Seki, K. & Murakami, H., 10 20 1993, : : BBA - Molecular Basis of Disease. 1182, 3, p. 257-263 7 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Carbohydrates
Light
Adenocarcinoma of lung
Antibodies
4 引用 (Scopus)

Immortalization of human T lymphocytes by oncogenes

Okano, F., Tachibana, H., Akiyama, K., Shirahata, S. & Murakami, H., 1 1 1993, : : Cytotechnology. 11, 3, p. 205-211 7 p.

研究成果: ジャーナルへの寄稿記事

T-cells
Oncogenes
Cells
T-Lymphocytes
Cell Line
8 引用 (Scopus)

Secretory cell immunoscreening assay - A highly sensitive screening method for secretory cells

Teruya, K., Shirahata, S., Yano, T., Seki, K., Tachibana, H., Ohashi, H. & Murakami, H., 11 1 1993, : : Analytical Biochemistry. 214, 2, p. 468-473 6 p.

研究成果: ジャーナルへの寄稿記事

Assays
Screening
Interleukin-6
Membranes
Proteins
2 引用 (Scopus)

The detection of a breast cancer antigen on MCF-7 cells reactive with the TCR(α) of a specific killer T cell line

Okano, F., Tachibana, H., Akiyama, K. & Murakami, H., 9 1 1993, : : Biotherapy. 6, 3, p. 195-203 9 p.

研究成果: ジャーナルへの寄稿記事

MCF-7 Cells
T-Cell Antigen Receptor
Breast Neoplasms
T-Lymphocytes
Antigens
1992
21 引用 (Scopus)

Generation of specificity-variant antibodies by alteration of carbohydrate in light chain of human monoclonal antibodies

Tachibana, H., Shirahata, S. & Murakami, H., 12 15 1992, : : Biochemical and Biophysical Research Communications. 189, 2, p. 625-632 8 p.

研究成果: ジャーナルへの寄稿記事

Antibody Specificity
Monoclonal Antibodies
Carbohydrates
Light
Antigens
14 引用 (Scopus)

Growth stimulating activity of heat shock protein 90α to lymphoid cell lines in serum-free medium

Kuroita, T., Tachibana, H., Ohashi, H., Shirahata, S. & Murakami, H., 6 1 1992, : : Cytotechnology. 8, 2, p. 109-117 9 p.

研究成果: ジャーナルへの寄稿記事

HSP90 Heat-Shock Proteins
Serum-Free Culture Media
Cells
Lymphocytes
Proteins
24 引用 (Scopus)

In vitro immunization of human lymphocytes with human lung cancer cell line A549

Kawahara, H., Shirahata, S., Tachibana, H. & Murakami, H., 1 1 1992, : : Human Antibodies. 3, 1, p. 8-13 6 p.

研究成果: ジャーナルへの寄稿記事

Immunization
Lung Neoplasms
Lymphocytes
Antibodies
Hybridomas
3 引用 (Scopus)

Stimulation of Interferon β Production of Cultured Cells by Phospholipids in Foodstuffs

Tahara, T., Shirahata, S., Osada, K., Tachibana, H., Murakami, H. & Kazuki, S., 1 1 1992, : : Bioscience, Biotechnology and Biochemistry. 56, 9, p. 1465-1466 2 p.

研究成果: ジャーナルへの寄稿記事

Phosphatidylethanolamines
Lysophospholipids
Poly I-C
Lysophosphatidylcholines
Interferon-beta
1991
4 引用 (Scopus)

Altered reactivity of immunoglobulin produced by human-human hybridoma cells transfected by pSV2-neo gene

Tachibana, H., Akiyama, K., Shirahata, S. & Murakami, H., 7 1 1991, : : Cytotechnology. 6, 3, p. 219-226 8 p.

研究成果: ジャーナルへの寄稿記事

Hybridomas
Monoclonal antibodies
Carboxypeptidases A
Immunoglobulins
DNA

Changes in Specificities of Human Monoclonal Antibodies by Introduction of Drug-resistance Gene into Hybridomas

Shirahata, S., Mori, T., Seki, K., Murakami, H., Tachibana, H. & Yamada, K., 1 1 1991, : : Agricultural and Biological Chemistry. 55, 6, p. 1689-1691 3 p.

研究成果: ジャーナルへの寄稿記事

Genes
Monoclonal Antibodies
Pharmaceutical Preparations

Changes in specificities of human monoclonal antibodies by introduction of drug-resistance gene into hybridomas.

Shirahata, S., Tachibana, H., Mori, T., Seki, K., Yamada, K. & Murakami, H., 6 1 1991, : : Agricultural and Biological Chemistry. 55, 6, p. 1689-1691 3 p.

研究成果: ジャーナルへの寄稿記事

Decreasd Autologous Fluorescence in Flow Cytometry of Cultured Cells

Kawahara, H., Yamada, K., Akiyama, K., Tachibana, H., Shirahata, S. & Murakami, H., 1 1 1991, : : Nippon Nogeikagaku Kaishi. 65, 5, p. 879-881 3 p.

研究成果: ジャーナルへの寄稿記事

Flow cytometry
cultured cells
flow cytometry
Cultured Cells
Flow Cytometry
5 引用 (Scopus)

Generation of Human-mouse Hybridoma Secreting Human IgM Class Anti-neocarzinostatin Antibody and Its Application to Hybrid Hybridoma

Shinmoto, H., Tachibana, H., Dosako, S. I., Shirahata, S. & Murakami, H., 1 1 1991, : : Agricultural and Biological Chemistry. 55, 11, p. 2883-2885 3 p.

研究成果: ジャーナルへの寄稿記事

Zinostatin
Thioguanine
Diphtheria Toxin
Immunoglobulin M
Animals
7 引用 (Scopus)

Generation of hybrid hybridomas secreting human IgM class hybrid antiricin and antidiphtheria toxin antibodies

Shinmoto, H., Dosako, S., Tachibana, H., Yamada, K., Shirahata, S. & Murakami, H., 1 1 1991, : : Human Antibodies. 2, 1, p. 39-41 3 p.

研究成果: ジャーナルへの寄稿記事

Hybridomas
Immunoglobulin M
Antibodies
Light
Immunoglobulin Subunits
4 引用 (Scopus)

Increased antigen binding strengths of hybrid antibodies produced by human hybrid hybridomas

Tachibana, H., Shirahata, S., Kawahara, H. & Murakami, H., 9 1 1991, : : Cytotechnology. 7, 1, p. 1-6 6 p.

研究成果: ジャーナルへの寄稿記事

Hybridomas
Antigens
Antibodies
DNA
Peptide Hydrolases
1987
2 引用 (Scopus)

Stimulation by 2-Mercaptoethanol and Alcohols of Protease in Antarctic Krill, Euphausia superba, at Low Temperatures

Yamada, K., Murakami, H., Tachibana, H., Watanabe, Y. & Omura, H., 1 1 1987, : : Agricultural and Biological Chemistry. 51, 12, p. 3363-3368 6 p.

研究成果: ジャーナルへの寄稿記事

Euphausiacea
Euphausia superba
Mercaptoethanol
Peptide Hydrolases
proteinases