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研究成果 1999 2019

  • 1665 引用
  • 20 h指数
  • 33 記事
  • 3 レター
  • 3 評論記事
  • 1 コメント/討論
フィルター
記事
1999
62 引用 (Scopus)

Differential response of macrophage subpopulations to myelin degradation in the injured rat sciatic nerve

Hirata, K., Mitoma, H., Ueno, N., He, J. W. & Kawabuchi, M., 12 1 1999, : : Journal of Neurocytology. 28, 8, p. 685-695 11 p.

研究成果: ジャーナルへの寄稿記事

Sciatic Nerve
Myelin Sheath
Macrophages
Phagocytosis
Confocal Microscopy
2004
12 引用 (Scopus)

Association of A Four-Amino Acid Residue Insertion Polymorphism of the HS1 Gene with Systemic Lupus Erythematosus: Molecular and Functional Analysis

Otsuka, J., Horiuchi, T., Yoshizawa, S., Tsukamoto, H., Sawabe, T., Kikuchi, Y., Himeji, D., Koyama, T., Mitoma, H., Watanabe, T. & Harada, M., 3 1 2004, : : Arthritis and rheumatism. 50, 3, p. 871-881 11 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
B-Lymphocytes
Amino Acids
Genes
Proline
20 引用 (Scopus)

Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese.

Horiuchi, T., Tsukamoto, H., Mitoma, H., Miyagawa, H., Tamimoto, Y., Yoshizawa, S., Harada, M., Hayashi, K., Hashimura, C., Oribe, M. & Okamura, S., 1 1 2004, : : International journal of molecular medicine. 14, 5, p. 813-818 6 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
Mutation
Rheumatoid Arthritis
Missense Mutation
Autosomal Dominant Familial Periodic Fever
2005
52 引用 (Scopus)

Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologus PBSCT

Horiuchi, T., Gondo, H., Miyagawa, H., Otsuka, J., Inaba, S., Nagafuji, K., Takase, K., Tsukamoto, H., Koyama, T., Mitoma, H., Tamimoto, Y., Miyagi, Y., Tahira, T., Hayashi, K., Hashimura, C., Okamura, S. & Harada, M., 3 1 2005, : : Genes and Immunity. 6, 2, p. 162-166 5 p.

研究成果: ジャーナルへの寄稿記事

Mannose-Binding Lectin
Bacterial Infections
Peripheral Blood Stem Cell Transplantation
Gene Frequency
Drug Therapy
40 引用 (Scopus)

Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus.

Mitoma, H., Horiuchi, T., kimoto, Y., Tsukamoto, H., Uchino, A., Tamimoto, Y., Miyagi, Y. & Harada, M., 1 1 2005, : : International journal of molecular medicine. 16, 4, p. 609-615 7 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-21 Receptors
Systemic Lupus Erythematosus
B-Lymphocytes
B-Lymphocyte Subsets
Lymphopenia
217 引用 (Scopus)

Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-α

Mitoma, H., Horiuchi, T., Hatta, N., Tsukamoto, H., Harashima, S. I., Kikuchi, Y., Otsuka, J., Okamura, S., Fujita, S. & Harada, M., 1 1 2005, : : Gastroenterology. 128, 2, p. 376-392 17 p.

研究成果: ジャーナルへの寄稿記事

Anti-Inflammatory Agents
Tumor Necrosis Factor-alpha
Apoptosis
E-Selectin
JNK Mitogen-Activated Protein Kinases
20 引用 (Scopus)

Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus

Tsukamoto, H., Horiuchi, T., Kokuba, H., Nagae, S., Nishizaka, H., Sawabe, T., Harashima, S. I., Himeji, D., Koyama, T., Otsuka, J., Mitoma, H., kimoto, Y., Hashimura, C., Kitano, E., Kitamura, H., Furue, M. & Harada, M., 4 29 2005, : : Biochemical and Biophysical Research Communications. 330, 1, p. 298-304 7 p.

研究成果: ジャーナルへの寄稿記事

RNA Splice Sites
Systemic Lupus Erythematosus
Exons
Introns
Complementary DNA
2006
10 引用 (Scopus)

Increased expression of membrane TNF-α on activated peripheral CD8+ T cells in systemic lupus erythematosus

Horiuchi, T., Morita, C., Tsukamoto, H., Mitoma, H., Sawabe, T., Harashima, S. I., Kashiwagi, Y. & Okamura, S., 5 1 2006, : : International journal of molecular medicine. 17, 5, p. 875-879 5 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
T-Lymphocytes
Membranes
Autoantigens
Rheumatoid Arthritis
2007
38 引用 (Scopus)

A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: A case-control study and a meta-analysis

Horiuchi, T., Kiyohara, C., Tsukamoto, H., Sawabe, T., Furugo, I., Yoshizawa, S., Ueda, A., Tada, Y., Nakamura, T., Kimoto, Y., Mitoma, H., Harashima, S., Yoshizawa, S., Shimoda, T., Okamura, S., Nagasawa, K. & Harada, M., 3 1 2007, : : Annals of the Rheumatic Diseases. 66, 3, p. 320-324 5 p.

研究成果: ジャーナルへの寄稿記事

Receptors, Tumor Necrosis Factor, Type II
Polymorphism
Systemic Lupus Erythematosus
Meta-Analysis
Case-Control Studies
2008
44 引用 (Scopus)

A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: Immunological analysis of B cells, T cells and cytokines

Tamimoto, Y., Horiuchi, T., Tsukamoto, H., Otsuka, J., Mitoma, H., kimoto, Y., Nakashima, H., Muta, K., Abe, Y., Kiyohara, C., Ueda, A., Nagasawa, K., Yoshizawa, S., Shimoda, T. & Harada, M., 6 1 2008, : : Rheumatology. 47, 6, p. 821-827 7 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
B-Lymphocytes
Cytokines
T-Lymphocytes
Therapeutics
265 引用 (Scopus)

Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor α-expressing cells: Comparison among infliximab, etanercept, and adalimumab

Mitoma, H., Horiuchi, T., Tsukamoto, H., Tamimoto, Y., kimoto, Y., Uchino, A., To, K., Harashima, S. I., Hatta, N. & Harada, M., 5 1 2008, : : Arthritis and rheumatism. 58, 5, p. 1248-1257 10 p.

研究成果: ジャーナルへの寄稿記事

Tumor Necrosis Factor-alpha
Antibody-Dependent Cell Cytotoxicity
Granulomatosis with Polyangiitis
Jurkat Cells
Crohn Disease
2010
15 引用 (Scopus)

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections

kimoto, Y., Horiuchi, T., Tsukamoto, H., Kiyohara, C., Mitoma, H., Uchino, A., Furugo, I., Yoshizawa, S., Ueda, A., Harashima, S., Sawabe, T., Tahira, T., Hayashi, K., Yoshizawa, S., Shimoda, T., Akashi, K. & Harada, M., 4 5 2010, : : Rheumatology. 49, 7, p. 1346-1353 8 p., keq050.

研究成果: ジャーナルへの寄稿記事

KIR2DL5 Receptor
Systemic Lupus Erythematosus
Odds Ratio
KIR Receptors
Infection
27 引用 (Scopus)

Safety and potential efficacy of tacrolimus for treatment of lupus nephritis with persistent proteinuria

Uchino, A., Tsukamoto, H., Nakashima, H., Yoshizawa, S., Furugo, I., Mitoma, H., Oryoji, K., Shimoda, T., Niiro, H., Tada, Y., Yano, T., Nonaka, T., Oishi, R., Akashi, K. & Horiuchi, T., 3 23 2010, : : Clinical and experimental rheumatology. 28, 1, p. 6-12 7 p.

研究成果: ジャーナルへの寄稿記事

Lupus Nephritis
Tacrolimus
Proteinuria
Safety
Therapeutics
10 引用 (Scopus)

Wegener's granulomatosis detected initially by integrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography

Ueda, N., Inoue, Y., Himeji, D., Shimao, Y., Oryoji, K., Mitoma, H., Arinobu, Y., Niiro, H., Tsukamoto, H., Horiuchi, T., Ueda, A. & Akashi, K., 4 1 2010, : : Modern Rheumatology. 20, 2, p. 205-209 5 p.

研究成果: ジャーナルへの寄稿記事

Granulomatosis with Polyangiitis
Fluorodeoxyglucose F18
Early Diagnosis
Mucous Membrane
Biopsy
2011
34 引用 (Scopus)

Analysis of immune reconstitution after autologous CD34 + stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 + t cells

Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., 5 1 2011, : : Rheumatology. 50, 5, p. 944-952 9 p., keq414.

研究成果: ジャーナルへの寄稿記事

Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
Stem Cells
Sclerosis
9 引用 (Scopus)

Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus

Furukawa, M., Kiyohara, C., Tsukamoto, H., Mitoma, H., Kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T., Akashi, K., Harada, M. & Horiuchi, T., 3 1 2011, : : Rheumatology International. 31, 3, p. 365-376 12 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
Bone Density
Spine
Metabolic Bone Diseases
Hip
2012
41 引用 (Scopus)

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity

Tanaka, A., Tsukamoto, H., Mitoma, H., Kiyohara, C., Ueda, N., Ayano, M., Ohta, S. I., Inoue, Y., Arinobu, Y., Niiro, H., Horiuchi, T. & Akashi, K., 11 11 2012, : : Arthritis Research and Therapy. 14, 6, R244.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
Serum
Toll-Like Receptor 9
Interleukin-6
Blood Cells
2013
13 引用 (Scopus)

Prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus

Furukawa, M., Kiyohara, C., Horiuchi, T., Tsukamoto, H., Mitoma, H., kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T., Harada, M. & Akashi, K., 7 1 2013, : : Modern Rheumatology. 23, 4, p. 765-773 9 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
Odds Ratio
Confidence Intervals
Bone Density
Spine
33 引用 (Scopus)

The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factorα

Ueda, N., Tsukamoto, H., Mitoma, H., Ayano, M., Tanaka, A., Ohta, S. I., Inoue, Y., Arinobu, Y., Niiro, H., Akashi, K. & Horiuchi, T., 5 1 2013, : : Inflammatory Bowel Diseases. 19, 6, p. 1224-1231 8 p.

研究成果: ジャーナルへの寄稿記事

Antibody-Dependent Cell Cytotoxicity
Tumor Necrosis Factor-alpha
Crohn Disease
Jurkat Cells
Tumor Necrosis Factor Receptors
92 引用 (Scopus)

The DHX33 RNA Helicase Senses Cytosolic RNA and Activates the NLRP3 Inflammasome

Mitoma, H., Hanabuchi, S., Kim, T., Bao, M., Zhang, Z., Sugimoto, N. & Liu, Y. J., 7 25 2013, : : Immunity. 39, 1, p. 123-135 13 p.

研究成果: ジャーナルへの寄稿記事

RNA Helicases
Inflammasomes
RNA
Bacterial RNA
Caspase 1
2014
16 引用 (Scopus)

Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system

Sugimoto, N., Mitoma, H., Kim, T., Hanabuchi, S. & Liu, Y. J., 5 27 2014, : : Proceedings of the National Academy of Sciences of the United States of America. 111, 21, p. 7747-7752 6 p.

研究成果: ジャーナルへの寄稿記事

Nucleic Acids
Antiviral Agents
Proteins
aspartylglutamate
Fibroblasts
54 引用 (Scopus)

Human NLRP3 Inflammasome senses multiple types of bacterial RNAs

Sha, W., Mitoma, H., Hanabuchi, S., Bao, M., Weng, L., Sugimoto, N., Liu, Y., Zhang, Z., Zhong, J., Sun, B. & Liu, Y. J., 11 11 2014, : : Proceedings of the National Academy of Sciences of the United States of America. 111, 45, p. 16059-16064 6 p.

研究成果: ジャーナルへの寄稿記事

Bacterial RNA
Inflammasomes
Macrophages
Transfer RNA
Caspase 1
36 引用 (Scopus)

The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-Induced NLRP3 inflammasome activation

Weng, L., Mitoma, H., Tricot, C., Bao, M., Liu, Y., Zhang, Z. & Liu, Y. J., 10 1 2014, : : Journal of Immunology. 193, 7, p. 3676-3682 7 p.

研究成果: ジャーナルへの寄稿記事

Inflammasomes
Ubiquitin-Protein Ligases
RNA
Ubiquitination
Lysine
2015
14 引用 (Scopus)
Systemic Scleroderma
Endothelial Cells
Cytokines
T-Lymphocytes
Wounds and Injuries
7 引用 (Scopus)
Dermatomyositis
Interstitial Lung Diseases
Serum
Polymyositis
Protein S
2016
10 引用 (Scopus)

Generation mechanism of RANKL + effector memory B cells: Relevance to the pathogenesis of rheumatoid arthritis

Ota, Y., Niiro, H., Ota, S. I., Ueki, N., Tsuzuki, H., Nakayama, T., Mishima, K., Higashioka, K., Jabbarzadeh-Tabrizi, S., Mitoma, H., Akahoshi, M., Arinobu, Y., Kukita, A., Yamada, H., Tsukamoto, H. & Akashi, K., 3 16 2016, : : Arthritis Research and Therapy. 18, 1, 67.

研究成果: ジャーナルへの寄稿記事

B-Lymphocyte Subsets
Rheumatoid Arthritis
B-Lymphocytes
Interferons
Osteoprotegerin
6 引用 (Scopus)

Quality of life in Japanese female patients with systemic lupus erythematosus: Evaluation using the Short Form 36 Health Survey

Furukawa, M., Kiyohara, C., Horiuchi, T., Tsukamoto, H., Mitoma, H., kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T. & Akashi, K., 3 3 2016, : : Modern Rheumatology. 26, 2, p. 240-247 8 p.

研究成果: ジャーナルへの寄稿記事

Health Surveys
Systemic Lupus Erythematosus
Odds Ratio
Quality of Life
Soybeans
2017
34 引用 (Scopus)

Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer

Okugawa, Y., Toiyama, Y., Toden, S., Mitoma, H., Nagasaka, T., Tanaka, K., Inoue, Y., Kusunoki, M., Boland, C. R. & Goel, A., 1 1 2017, : : Gut. 66, 1, p. 107-117 11 p.

研究成果: ジャーナルへの寄稿記事

Oncogenes
Colorectal Neoplasms
Biomarkers
Small Nucleolar RNA
Recurrence
9 引用 (Scopus)

Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes

Tsuzuki, H., Arinobu, Y., Miyawaki, K., Takaki, A., Ota, S. I., Ota, Y., Mitoma, H., Akahoshi, M., Mori, Y., Iwasaki, H., Niiro, H., Tsukamoto, H. & Akashi, K., 1 1 2017, : : Immunology. 150, 1, p. 64-73 10 p.

研究成果: ジャーナルへの寄稿記事

Granulocytes
Hypersensitivity
Eosinophils
Basophils
Mast Cells
2018
5 引用 (Scopus)
glycohemoglobin
rheumatoid arthritis
tumor necrosis factors
Glycosylated Hemoglobin A
observational studies
35 引用 (Scopus)

Molecular mechanisms of action of anti-TNF-α agents – Comparison among therapeutic TNF-α antagonists

Mitoma, H., Horiuchi, T., Tsukamoto, H. & Ueda, N., 1 1 2018, : : Cytokine. 101, p. 56-63 8 p.

研究成果: ジャーナルへの寄稿記事

Tumor Necrosis Factor-alpha
Inflammatory Bowel Diseases
Immunoglobulin G
Therapeutics
Antibodies
2019

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Takaki-Kuwahara, A., Arinobu, Y., Miyawaki, K., Yamada, H., Tsuzuki, H., Irino, K., Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Tsukamoto, H., Horiuchi, T., Niiro, H. & Akashi, K., 8 30 2019, : : Arthritis Research and Therapy. 21, 1, 198.

研究成果: ジャーナルへの寄稿記事

公開
Rheumatoid Arthritis
Joints
Lymphocytes
Cytokines
Synovial Fluid
Phase II Clinical Trials
Clinical Trials, Phase I
Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Japan