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研究成果 1988 2019

フィルター
記事
39 引用 (Scopus)

5′-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients

Takahashi, H., Ieiri, I., Wilkinson, G. R., Mayo, G., Kashima, T., Kimura, S., Otsubo, K. & Echizen, H., 4 15 2004, : : Blood. 103, 8, p. 3055-3057 3 p.

研究成果: ジャーナルへの寄稿記事

5' Flanking Region
Warfarin
Polymorphism
Metabolism
Linkage Disequilibrium
15 引用 (Scopus)

A CYP2D6 Phenotype-Genotype Mismatch in Japanese Psychiatric Patients

Ieiri, I., Yamada, S., Seto, K., Morita, T., Kaneda, T., Mamiya, K., Tashiro, N., Higuchi, S. & Otsubo, K., 9 1 2003, : : Pharmacopsychiatry. 36, 5, p. 192-196 5 p.

研究成果: ジャーナルへの寄稿記事

Cytochrome P-450 CYP2D6
Psychiatry
Genotype
Phenotype
Psychotropic Drugs
31 引用 (Scopus)

Addition of bevacizumab enhances antitumor activity of erlotinib against non-small cell lung cancer xenografts depending on VEGF expression

Li, H., Takayama, K., Wang, S., Shiraishi, Y., Gotanda, K., Harada, T., Furuyama, K., Iwama, E., Ieiri, I., Okamoto, I. & Nakanishi, Y., 10 9 2014, : : Cancer chemotherapy and pharmacology. 74, 6, p. 1297-1305 9 p.

研究成果: ジャーナルへの寄稿記事

Heterografts
Non-Small Cell Lung Carcinoma
Vascular Endothelial Growth Factor A
Cells
Tumors
1 引用 (Scopus)

ANALYSIS OF THE FACTORS INFLUENCING ANTI‐EPILEPTIC DRUG CONCENTRATIONS‐CARBAMAZEPINE

Ichikou, N., Ieiri, I., Higuchi, S., Hirata, K., Yamada, H. & Aoyama, T., 1 1 1990, : : Journal of Clinical Pharmacy and Therapeutics. 15, 5, p. 337-349 13 p.

研究成果: ジャーナルへの寄稿記事

Carbamazepine
Anticonvulsants
Statistical Factor Analysis
Serum
Phenytoin
2 引用 (Scopus)

ANALYSIS OF THE FACTORS INFLUENCING ANTI‐EPILEPTIC DRUG CONCENTRATIONS‐VALPROIC ACID

Ieiri, I., Higuchi, S., Hirata, K., Yamada, H. & Aoyama, T., 1 1 1990, : : Journal of Clinical Pharmacy and Therapeutics. 15, 5, p. 351-363 13 p.

研究成果: ジャーナルへの寄稿記事

Valproic Acid
Anticonvulsants
Statistical Factor Analysis
Acids
Carbamazepine
36 引用 (Scopus)

Apple juice greatly reduces systemic exposure to atenolol

Jeon, H., Jang, I. J., Lee, S., Ohashi, K., Kotegawa, T., Ieiri, I., Cho, J. Y., Yoon, S. H., Shin, S. G., Yu, K. S. & Lim, K. S., 1 2013, : : British Journal of Clinical Pharmacology. 75, 1, p. 172-179 8 p.

研究成果: ジャーナルへの寄稿記事

Atenolol
Malus
Pharmacokinetics
Water
Healthy Volunteers
17 引用 (Scopus)
5' Flanking Region
DNA methylation
DNA Methylation
placenta
Individuality
12 引用 (Scopus)

Association of multidrug resistance-associated protein 2 single nucleotide polymorphism rs12762549 with the basal plasma levels of phase II metabolites of isoflavonoids in healthy Japanese individuals

Kato, K., Kusuhara, H., Kumagai, Y., Ieiri, I., Mori, H., Ito, S., Nakai, Y., Maeda, K. & Sugiyama, Y., 5 1 2012, : : Pharmacogenetics and Genomics. 22, 5, p. 344-354 11 p.

研究成果: ジャーナルへの寄稿記事

Single Nucleotide Polymorphism
Genistein
Liquid Chromatography
Mass Spectrometry
Metabolomics
119 引用 (Scopus)

Association of pharmacokinetic (CY72C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and γ-glutamyl carboxylase) gene variants with warfarin sensitivity

Shikata, E., Ieiri, I., Ishiguro, S., Aono, H., Inoue, K., Koide, T., Ohgi, S. & Otsubo, K., 4 1 2004, : : Blood. 103, 7, p. 2630-2635 6 p.

研究成果: ジャーナルへの寄稿記事

Pharmacodynamics
Factor VII
Pharmacokinetics
Protein S
Prothrombin
11 引用 (Scopus)

Association of polymorphisms in the cytochrome P450 (CYP) 2C19 and 2C18 genes in Japanese epileptic patients

Mamiya, K., Ieiri, I., Miyahara, S., Imai, J., Furuumi, H., Fukumaki, Y., Ninomiya, H., Tashiro, N., Yamada, H. & Higuchi, S., 3 16 1998, : : Pharmacogenetics. 8, 1, p. 87-90 4 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure

Endo, S., Fukahori, A., Tokuhiro, S., Shinagawa, A., Walker, J., Yoshihara, K., Ishizuka, H., Ieiri, I. & Sugiyama, Y., 8 1 2012, : : Journal of Human Genetics. 57, 8, p. 531-544 14 p.

研究成果: ジャーナルへの寄稿記事

Genetic Polymorphisms
Hispanic Americans
African Americans
Haplotypes
Pharmacokinetics
7 引用 (Scopus)

Characterization of ADME gene variation in 21 populations by exome sequencing

Hovelson, D. H., Xue, Z., Zawistowski, M., Ehm, M. G., Harris, E. C., Stocker, S. L., Gross, A. S., Jang, I. J., Ieiri, I., Lee, J. E., Cardon, L. R., Chissoe, S. L., Abecasis, G. & Nelson, M. R., 1 1 2017, : : Pharmacogenetics and Genomics. 27, 3, p. 89-100 12 p.

研究成果: ジャーナルへの寄稿記事

Exome
Population
Genes
Gene Frequency
1 引用 (Scopus)

Characterization of changes in HbA1c in patients with and without secondary failure after metformin treatments by a population pharmacodynamic analysis using mixture models

Tamaki, Y., Maema, K., Kakara, M., Fukae, M., Kinoshita, R., Kashihara, Y., Muraki, S., Hirota, T. & Ieiri, I., 12 1 2018, : : Drug metabolism and pharmacokinetics. 33, 6, p. 264-269 6 p.

研究成果: ジャーナルへの寄稿記事

Metformin
Population
Therapeutics
Electronic Health Records
Glycosylated Hemoglobin A
94 引用 (Scopus)

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2

Hirouchi, M., Suzuki, H., Itoda, M., Ozawa, S., Sawada, J. I., Ieiri, I., Ohtsubo, K. & Sugiyama, Y., 5 1 2004, : : Pharmaceutical Research. 21, 5, p. 742-748 7 p.

研究成果: ジャーナルへの寄稿記事

Polymorphism
LLC-PK1 Cells
Single Nucleotide Polymorphism
Nucleotides
Membranes
41 引用 (Scopus)

Circadian disruption accelerates tumor growth and angio/stromagenesis through a wnt signaling pathway

Yasuniwa, Y., Izumi, H., Wang, K. Y., Shimajiri, S., Sasaguri, Y., Kawai, K., Kasai, H., Shimada, T., Miyake, K., Kashiwagi, E., Hirano, G., Kidani, A., Akiyama, M., Han, B., Wu, Y., Ieiri, I., Higuchi, S. & Kohno, K., 12 1 2010, : : PloS one. 5, 12, e15330.

研究成果: ジャーナルへの寄稿記事

Wnt Signaling Pathway
Tumors
neoplasms
Growth
Neoplasms
9 引用 (Scopus)

Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines

Gotanda, K., Hirota, T., Saito, J., Fukae, M., Egashira, Y., Izumi, N., Deguchi, M., Kimura, M., Matsuki, S., Irie, S. & Ieiri, I., 8 30 2016, : : Scientific reports. 6, 32299.

研究成果: ジャーナルへの寄稿記事

Intestines
Biomarkers
Breast Neoplasms
Proteins
Area Under Curve
19 引用 (Scopus)

Clarification of the mechanism of clopidogrel-mediated drug-drug interaction in a clinical cassette small-dose study and its prediction based on in vitro information

Kim, S. J., Yoshikado, T., Ieiri, I., Maeda, K., Kimura, M., Irie, S., Kusuhara, H. & Sugiyama, Y., 10 1 2016, : : Drug Metabolism and Disposition. 44, 10, p. 1622-1632 11 p.

研究成果: ジャーナルへの寄稿記事

clopidogrel
repaglinide
pioglitazone
Drug Interactions
Pharmaceutical Preparations

Clinically applicable pharmacogenomics of anti-cancer drugs

Ieiri, I. & Higuchi, S., 11 1 2008, : : Japanese Journal of Clinical Pharmacology and Therapeutics. 39, 6, p. 233-237 5 p.

研究成果: ジャーナルへの寄稿記事

irinotecan
Pharmacogenetics
ATP-Binding Cassette Transporters
Drug Therapy
Pharmaceutical Preparations
Human Body
Pharmacokinetics
Pharmaceutical Preparations
Renal Elimination
26 引用 (Scopus)

Comparison of pharmacokinetics, pharmacodynamics, safety, and tolerability of the amyloid β monoclonal antibody solanezumab in japanese and white patients with mild to moderate Alzheimer disease

Uenaka, K., Nakano, M., Willis, B. A., Friedrich, S., Ferguson-Sells, L., Dean, R. A., Ieiri, I. & Siemers, E. R., 1 1 2012, : : Clinical Neuropharmacology. 35, 1, p. 25-29 5 p.

研究成果: ジャーナルへの寄稿記事

solanezumab
Amyloid
Alzheimer Disease
Pharmacokinetics
Monoclonal Antibodies

Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism

Ieiri, I., Kishimoto, Y., Okochi, H., Momiyama, K., Morita, T., Kitano, M., Morisawa, T., Fukushima, Y., Nakagawa, K., Hasegawa, J., Otsubo, K. & Ishizaki, T., 5 23 2002, : : Cancer Chemotherapy and Pharmacology, Supplement. 49, 7, p. 485-492 8 p.

研究成果: ジャーナルへの寄稿記事

Rabeprazole
Lansoprazole
Gastrins
Serum
Proton Pump Inhibitors
57 引用 (Scopus)

Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism

Ieiri, I., Kishimoto, Y., Okochi, H., Momiyama, K., Morita, T., Kitano, M., Morisawa, T., Fukushima, Y., Nakagawa, K., Hasegawa, J., Otsubo, K. & Ishizaki, T., 2001, : : European Journal of Clinical Pharmacology. 57, 5-6, p. 485-492 8 p.

研究成果: ジャーナルへの寄稿記事

Rabeprazole
Lansoprazole
Gastrins
Serum
Proton Pump Inhibitors

Contribution of angiotensin converting enzyme gene polymorphism to the action of angiotensin II receptor antagonist (CS-866)

Urae, A., Okada, M., Ieiri, I., Higuchi, S., Hisaoka, M., Tajima, M., Ogihara, T. & Nakano, S., 1 1 2002, : : Japanese Journal of Clinical Pharmacology and Therapeutics. 33, 2, p. 37-46 10 p.

研究成果: ジャーナルへの寄稿記事

Angiotensin Receptor Antagonists
Peptidyl-Dipeptidase A
Genotype
Genes
Angiotensin II
57 引用 (Scopus)

CYP2C19 polymorphism effect on phenobarbitone. Pharmacokineties in Japanese patients with epilepsy: Analysis by population pharmacokinetics

Mamiya, K., Hadama, A., Yukawa, E., Ieiri, I., Otsubo, K., Ninomiya, H., Tashiro, N. & Higuchi, S., 1 1 2000, : : European Journal of Clinical Pharmacology. 55, 11-12, p. 821-825 5 p.

研究成果: ジャーナルへの寄稿記事

Phenobarbital
Epilepsy
Pharmacokinetics
Population
Genotype
296 引用 (Scopus)

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

Takahashi, H., Wilkinson, G. R., Nutescu, E. A., Morita, T., Ritchie, M. D., Scordo, M. G., Pengo, V., Barban, M., Padrini, R., Ieiri, I., Otsubo, K., Kashima, T., Kimura, S., Kijima, S. & Echizen, H., 1 1 2006, : : Pharmacogenetics and Genomics. 16, 2, p. 101-110 10 p.

研究成果: ジャーナルへの寄稿記事

Warfarin
African Americans
Population
Prothrombin
Vitamin K Epoxide Reductases
39 引用 (Scopus)

Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues

Hirota, T., Date, Y., Nishibatake, Y., Takane, H., Fukuoka, Y., Taniguchi, Y., Burioka, N., Shimizu, E., Nakamura, H., Otsubo, K. & Ieiri, I., 7 1 2012, : : Lung Cancer. 77, 1, p. 16-23 8 p.

研究成果: ジャーナルへの寄稿記事

Dihydrouracil Dehydrogenase (NADP)
MicroRNAs
Lung
Fluorouracil
Neoplasms
5 引用 (Scopus)

Direct and rapid genotyping of glutathione-S-transferase M1 and T1 from human blood specimens using the SmartAmp2 method

Okada, R., Ishizu, Y., Endo, R., Lezhava, A., Ieiri, I., Kusuhara, H., Sugiyama, Y. & Hayashizaki, Y., 10 1 2010, : : Drug Metabolism and Disposition. 38, 10, p. 1636-1639 4 p.

研究成果: ジャーナルへの寄稿記事

Genotype
DNA
Disease Susceptibility
Drug-Related Side Effects and Adverse Reactions
Electrophoresis
2 引用 (Scopus)

Direct and rapid genotyping of SLCO1B1 388A>G and 521T>C in human blood specimens using the SmartAmp-2 method

Yoshida, K., Takano, J., Ishizu, Y., Lezhava, A., Ieiri, I., Maeda, K., Hayashizaki, Y. & Sugiyama, Y., 4 1 2013, : : AAPS Journal. 15, 2, p. 618-622 5 p.

研究成果: ジャーナルへの寄稿記事

Genotype
Solute Carrier Organic Anion Transporter Family Member 1b1
Anions
Pharmacokinetics
Pharmaceutical Preparations
8 引用 (Scopus)

Dosing time-dependency of the arthritis-inhibiting effect of tacrolimus in mice

Obayashi, K., Tomonari, M., Yoshimatsu, H., Fukuyama, R., Ieiri, I., Higuchi, S. & To, H., 7 21 2011, : : Journal of Pharmacological Sciences. 116, 3, p. 264-273 10 p.

研究成果: ジャーナルへの寄稿記事

Tacrolimus
Arthritis
Rheumatoid Arthritis
Serum Amyloid A Protein
Experimental Arthritis
19 引用 (Scopus)

Drug interactions of zonisamide with phenytoin and sodium valproate: serum concentrations and protein binding

Tasaki, K., Minami, T., Ieiri, I., Ohtsubo, K., Hirakawa, Y., Ueda, K. & Higuchi, S., 1 1 1995, : : Brain and Development. 17, 3, p. 182-185 4 p.

研究成果: ジャーナルへの寄稿記事

zonisamide
Valproic Acid
Phenytoin
Drug Interactions
Protein Binding
17 引用 (Scopus)

Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study

Ieiri, I., Goto, W., Higuchi, S., Hirata, K., Toshitani, A., Imayama, S., Ohyama, Y., Yamada, H. & Ohtsubo, K., 11 1 1995, : : European Journal of Clinical Pharmacology. 49, 1-2, p. 51-56 6 p.

研究成果: ジャーナルへの寄稿記事

Gingival Hyperplasia
Phenytoin
Fibroblasts
Poisons
In Vitro Techniques
3 引用 (Scopus)

Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers

Mori, D., Kashihara, Y., Yoshikado, T., Kimura, M., Hirota, T., Matsuki, S., Maeda, K., Irie, S., Ieiri, I., Sugiyama, Y. & Kusuhara, H., 2 1 2019, : : Drug metabolism and pharmacokinetics. 34, 1, p. 78-86 9 p.

研究成果: ジャーナルへの寄稿記事

Sulfates
Healthy Volunteers
Genotype
fluvastatin
Pharmaceutical Preparations
10 引用 (Scopus)

Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine-alprazolam interaction in patients with psychosomatic disease

Sugahara, H., Maebara, C., Ohtani, H., Handa, M., Ando, K., Mine, K., Kubo, C., Ieiri, I. & Sawada, Y., 7 1 2009, : : European Journal of Clinical Pharmacology. 65, 7, p. 699-704 6 p.

研究成果: ジャーナルへの寄稿記事

Alprazolam
Fluvoxamine
Cytochrome P-450 CYP2D6
Smoking
Cytochrome P-450 CYP3A

Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation

Kashihara, Y., Terao, Y., Yoda, K., Hirota, T., Kubota, T., Kimura, M., Matsuki, S., Hirakawa, M., Irie, S. & Ieiri, I., 3 6 2019, : : European Journal of Clinical Pharmacology. 75, 3, p. 351-361 11 p.

研究成果: ジャーナルへの寄稿記事

Magnesium Oxide
Carbidopa
Levodopa
Pharmacokinetics
Meta-Analysis
6 引用 (Scopus)

Effects of multiple-dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers

Akamine, Y., Miura, M., Yasui-Furukori, N., Ieiri, I. & Uno, T., 1 1 2015, : : Journal of Clinical Pharmacy and Therapeutics. 40, 1, p. 98-103 6 p.

研究成果: ジャーナルへの寄稿記事

fexofenadine
Rifampin
Volunteers
Pharmacokinetics
P-Glycoprotein
13 引用 (Scopus)

Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers

Akamine, Y., Miura, M., Komori, H., Saito, S., Kusuhara, H., Tamai, I., Ieiri, I., Uno, T. & Yasui-Furukori, N., 1 1 2014, : : European Journal of Clinical Pharmacology. 70, 9, p. 1087-1095 9 p.

研究成果: ジャーナルへの寄稿記事

fexofenadine
Malus
Pharmacokinetics
Eating
Anions
163 引用 (Scopus)

Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

Maeda, K., Ieiri, I., Yasuda, K., Fujino, A., Fujiwara, H., Otsubo, K., Hirano, M., Watanabe, T., Kitamura, Y., Kusuhara, H. & Sugiyama, Y., 5 1 2006, : : Clinical Pharmacology and Therapeutics. 79, 5, p. 427-439 13 p.

研究成果: ジャーナルへの寄稿記事

Valsartan
Pravastatin
Haplotypes
Anions
Pharmacokinetics
17 引用 (Scopus)

Effects of the serotonin 1A, 2A, 2C, 3A, and 3B and serotonin transporter gene polymorphisms on the occurrence of paroxetine discontinuation syndrome

Murata, Y., Kobayashi, D., Imuta, N., Haraguchi, K., Ieiri, I., Nishimura, R., Koyama, S. & Mine, K., 2 1 2010, : : Journal of Clinical Psychopharmacology. 30, 1, p. 11-17 7 p.

研究成果: ジャーナルへの寄稿記事

Paroxetine
Serotonin Plasma Membrane Transport Proteins
Serotonin
Genes
Receptor, Serotonin, 5-HT1A
3 引用 (Scopus)

Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis

Inoue, H., Tamaki, Y., Kashihara, Y., Muraki, S., Kakara, M., Hirota, T. & Ieiri, I., 2 1 2019, : : British journal of clinical pharmacology. 85, 2, p. 393-402 10 p.

研究成果: ジャーナルへの寄稿記事

Glucagon-Like Peptide 1
Metformin
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Meta-Analysis

Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters

Miyake, T., Mizuno, T., Takehara, I., Mochizuki, T., Kimura, M., Matsuki, S., Irie, S., Watanabe, N., Kato, Y., Ieiri, I., Maeda, K., Ando, O. & Kusuhara, H., 11 1 2019, : : Drug metabolism and disposition: the biological fate of chemicals. 47, 11, p. 1270-1280 11 p.

研究成果: ジャーナルへの寄稿記事

Drug Interactions
Cations
Biomarkers
Kidney
Pharmaceutical Preparations
81 引用 (Scopus)

Evaluation of in vivo P-glycoprotein function at the blood-brain barrier among MDR1 gene polymorphisms by using 11C-verapamil

Takano, A., Kusuhara, H., Suhara, T., Ieiri, I., Morimoto, T., Lee, Y. J., Maeda, J., Ikoma, Y., Ito, H., Suzuki, K. & Sugiyama, Y., 9 1 2006, : : Journal of Nuclear Medicine. 47, 9, p. 1427-1433 7 p.

研究成果: ジャーナルへの寄稿記事

P-Glycoprotein
Verapamil
Blood-Brain Barrier
Haplotypes
Genes
5 引用 (Scopus)

Evaluation of the therapeutic range of whole blood cyclosporin concentration in the treatment of psoriasis

Ieiri, I., Nakayama, J., Murakami, H., Hori, Y. & Higuchi, S., 3 20 1996, : : International Journal of Clinical Pharmacology and Therapeutics. 34, 3, p. 106-111 6 p.

研究成果: ジャーナルへの寄稿記事

Psoriasis
Cyclosporine
Therapeutics
Hypertension
Fluorescence Polarization Immunoassay
498 引用 (Scopus)

Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene

Tanabe, M., Ieiri, I., Nagata, N., Inoue, K., Ito, S., Kanamori, Y., Takahashi, M., Kurata, Y., Kigawa, J., Higuchi, S., Terakawa, N. & Otsubo, K., 6 1 2001, : : Journal of Pharmacology and Experimental Therapeutics. 297, 3, p. 1137-1143 7 p.

研究成果: ジャーナルへの寄稿記事

MDR Genes
P-Glycoprotein
Genetic Polymorphisms
Placenta
Single Nucleotide Polymorphism
28 引用 (Scopus)

Food-drug interaction of tacrolimus with pomelo, ginger, and turmeric juice in rats

Egashira, K., Sasaki, H., Higuchi, S. & Ieiri, I., 1 1 2012, : : Drug Metabolism and Pharmacokinetics. 27, 2, p. 242-247 6 p.

研究成果: ジャーナルへの寄稿記事

Food-Drug Interactions
Ginger
Curcuma
Tacrolimus
Citrus paradisi
39 引用 (Scopus)

Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain

Yamada, H., Ishii, K., Ishii, Y., Ieiri, I., Nishio, S., Morioka, T. & Oguri, K., 12 1 2003, : : Journal of Toxicological Sciences. 28, 5, p. 395-401 7 p.

研究成果: ジャーナルへの寄稿記事

Morphine
Analgesics
Brain
Glucuronides
Glucuronosyltransferase
131 引用 (Scopus)

Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C)

Iwai, M., Suzuki, H., Ieiri, I., Otsubo, K. & Sugiyama, Y., 11 1 2004, : : Pharmacogenetics. 14, 11, p. 749-757 9 p.

研究成果: ジャーナルへの寄稿記事

Organic Anion Transporters
Single Nucleotide Polymorphism
Liver
Pravastatin
HEK293 Cells

Functional Analysis of SNPs in Human OATP2 (OATP-C/SLC21A6)

Iwai, M., Suzuki, H., Sugiyama, Y., Nishizato, Y., Ieiri, I. & Otsubo, K., 12 1 2003, : : Japanese Pharmacology and Therapeutics. 31, SUPPL. 1

研究成果: ジャーナルへの寄稿記事

Solute Carrier Organic Anion Transporter Family Member 1b1
Single Nucleotide Polymorphism
209 引用 (Scopus)

Functional analysis of SNPs variants of BCRP/ABCG2

Kondo, C., Suzuki, H., Itoda, M., Ozawa, S., Sawada, J. I., Kobayashi, D., Ieiri, I., Mine, K., Ohtsubo, K. & Sugiyama, Y., 10 1 2004, : : Pharmaceutical Research. 21, 10, p. 1895-1903 9 p.

研究成果: ジャーナルへの寄稿記事

Functional analysis
Polymorphism
Single Nucleotide Polymorphism
Nucleotides
Complementary DNA
227 引用 (Scopus)

Functional assessment of ABCG2 (BRCP) gene polymorphisms to protein expression in human placenta

Kobayashi, D., Ieiri, I., Hirota, T., Takane, H., Maegawa, S., Kigawa, J., Suzuki, H., Nanba, E., Oshimura, M., Terakawa, N., Otsubo, K., Mine, K. & Sugiyama, Y., 1 1 2005, : : Drug Metabolism and Disposition. 33, 1, p. 94-101 8 p.

研究成果: ジャーナルへの寄稿記事

Placenta
Alleles
Allelic Imbalance
Terminator Codon
Genes
107 引用 (Scopus)
P-Glycoprotein
Genetic Polymorphisms
Breast Neoplasms
ATP-Binding Cassette Transporters
Pharmaceutical Preparations