Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1988 2019

フィルター
記事
2012
64 引用 (Scopus)

Microdosing clinical study: Pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose

Ieiri, I., Doi, Y., Maeda, K., Sasaki, T., Kimura, M., Hirota, T., Chiyoda, T., Miyagawa, M., Irie, S., Iwasaki, K. & Sugiyama, Y., 7 1 2012, : : Journal of Clinical Pharmacology. 52, 7, p. 1078-1089 12 p.

研究成果: ジャーナルへの寄稿記事

Celiprolol
Citrus paradisi
Pharmacogenetics
Pharmacokinetics
fexofenadine
14 引用 (Scopus)

Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing

Ieiri, I., Fukae, M., Maeda, K., Ando, Y., Kimura, M., Hirota, T., Nakamura, T., Iwasaki, K., Matsuki, S., Matsuguma, K., Kanda, E., Deguchi, M., Irie, S. & Sugiyama, Y., 10 1 2012, : : International Journal of Clinical Pharmacology and Therapeutics. 50, 10, p. 689-700 12 p.

研究成果: ジャーナルへの寄稿記事

Pharmacogenetics
Lansoprazole
Pharmacokinetics
Genotype
Glyburide
79 引用 (Scopus)

Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

Kusuhara, H., Furuie, H., Inano, A., Sunagawa, A., Yamada, S., Wu, C., Fukizawa, S., Morimoto, N., Ieiri, I., Morishita, M., Sumita, K., Mayahara, H., Fujita, T., Maeda, K. & Sugiyama, Y., 7 1 2012, : : British Journal of Pharmacology. 166, 6, p. 1793-1803 11 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Curcumin
Healthy Volunteers
Pharmacokinetics
Breast Neoplasms
Pharmacogenetics
Pharmacokinetics
Clinical Studies
5 引用 (Scopus)
Secretory Phospholipase A2
Acetylcysteine
Endothelial Cells
Tumor Necrosis Factor-alpha
LDL Lipoproteins
2011
8 引用 (Scopus)

Dosing time-dependency of the arthritis-inhibiting effect of tacrolimus in mice

Obayashi, K., Tomonari, M., Yoshimatsu, H., Fukuyama, R., Ieiri, I., Higuchi, S. & To, H., 7 21 2011, : : Journal of Pharmacological Sciences. 116, 3, p. 264-273 10 p.

研究成果: ジャーナルへの寄稿記事

Tacrolimus
Arthritis
Rheumatoid Arthritis
Serum Amyloid A Protein
Experimental Arthritis
17 引用 (Scopus)
Nucleic Acid Regulatory Sequences
Epigenomics
DNA Methylation
Acetylation
Histones
37 引用 (Scopus)

Methotrexate chronotherapy is effective against rheumatoid arthritis

To, H., Yoshimatsu, H., Tomonari, M., Ida, H., Tsurumoto, T., Tsuji, Y., Sonemoto, E., Shimasaki, N., Satoru, K., Sasaki, H., Ieiri, I., Higuchi, S., Kawakami, A., Ueki, Y. & Eguchi, K., 4 1 2011, : : Chronobiology International. 28, 3, p. 267-274 8 p.

研究成果: ジャーナルへの寄稿記事

Chronotherapy
Methotrexate
Rheumatoid Arthritis
Inbred MRL lpr Mouse
Tumor Necrosis Factor-alpha
39 引用 (Scopus)

Pharmacokinetic and pharmacogenomic profiles of telmisartan after the oral microdose and therapeutic dose

Ieiri, I., Nishimura, C., Maeda, K., Sasaki, T., Kimura, M., Chiyoda, T., Hirota, T., Irie, S., Shimizu, H., Noguchi, T., Yoshida, K. & Sugiyama, Y., 8 1 2011, : : Pharmacogenetics and Genomics. 21, 8, p. 495-505 11 p.

研究成果: ジャーナルへの寄稿記事

Pharmacogenetics
Pharmacokinetics
Linkage Disequilibrium
Haplotypes
Therapeutics
57 引用 (Scopus)

Population pharmacokinetic and pharmacodynamic analysis of linezolid and a hematologic side effect, thrombocytopenia, in Japanese patients

Sasaki, T., Takane, H., Ogawa, K., Isagawa, S., Hirota, T., Higuchi, S., Horii, T., Otsubo, K. & Ieiri, I., 5 1 2011, : : Antimicrobial Agents and Chemotherapy. 55, 5, p. 1867-1873 7 p.

研究成果: ジャーナルへの寄稿記事

Linezolid
Thrombocytopenia
Pharmacokinetics
Platelet Count
Population
10 引用 (Scopus)

Systematic screening of human ABCC3 polymorphisms and their effects on MRP3 expression and function

Sasaki, T., Hirota, T., Ryokai, Y., Kobayashi, D., Kimura, M., Irie, S., Higuchi, S. & Ieiri, I., 1 1 2011, : : Drug metabolism and pharmacokinetics. 26, 4, p. 374-386 13 p.

研究成果: ジャーナルへの寄稿記事

Hymecromone
Glucuronides
Genetic Polymorphisms
Reporter Genes
Pharmacokinetics
2010
41 引用 (Scopus)

Circadian disruption accelerates tumor growth and angio/stromagenesis through a wnt signaling pathway

Yasuniwa, Y., Izumi, H., Wang, K. Y., Shimajiri, S., Sasaguri, Y., Kawai, K., Kasai, H., Shimada, T., Miyake, K., Kashiwagi, E., Hirano, G., Kidani, A., Akiyama, M., Han, B., Wu, Y., Ieiri, I., Higuchi, S. & Kohno, K., 12 1 2010, : : PloS one. 5, 12, e15330.

研究成果: ジャーナルへの寄稿記事

Wnt Signaling Pathway
Tumors
neoplasms
Growth
Neoplasms
5 引用 (Scopus)

Direct and rapid genotyping of glutathione-S-transferase M1 and T1 from human blood specimens using the SmartAmp2 method

Okada, R., Ishizu, Y., Endo, R., Lezhava, A., Ieiri, I., Kusuhara, H., Sugiyama, Y. & Hayashizaki, Y., 10 1 2010, : : Drug Metabolism and Disposition. 38, 10, p. 1636-1639 4 p.

研究成果: ジャーナルへの寄稿記事

Genotype
DNA
Disease Susceptibility
Drug-Related Side Effects and Adverse Reactions
Electrophoresis
17 引用 (Scopus)

Effects of the serotonin 1A, 2A, 2C, 3A, and 3B and serotonin transporter gene polymorphisms on the occurrence of paroxetine discontinuation syndrome

Murata, Y., Kobayashi, D., Imuta, N., Haraguchi, K., Ieiri, I., Nishimura, R., Koyama, S. & Mine, K., 2 1 2010, : : Journal of Clinical Psychopharmacology. 30, 1, p. 11-17 7 p.

研究成果: ジャーナルへの寄稿記事

Paroxetine
Serotonin Plasma Membrane Transport Proteins
Serotonin
Genes
Receptor, Serotonin, 5-HT1A

Investigation of the determinant of the hepatic clearance of atorvastatin with cassette-microdose clinical study

Yoshida, K., Maeda, K., Kumagai, Y., Ieiri, I., Yamane, N. & Sugiyama, Y., 12 25 2010, : : Japanese Pharmacology and Therapeutics. 38, SUPPL.2

研究成果: ジャーナルへの寄稿記事

Liver
Clinical Studies
Atorvastatin Calcium
6 引用 (Scopus)

Population pharmacokinetics of tamsulosin hydrochloride in paediatric patients with neuropathic and non-neuropathic bladder

Tsuda, Y., Tatami, S., Yamamura, N., Tadayasu, Y., Sarashina, A., Liesenfeld, K. H., Staab, A., Schäfer, H. G., Ieiri, I. & Higuchi, S., 7 1 2010, : : British journal of clinical pharmacology. 70, 1, p. 88-101 14 p.

研究成果: ジャーナルへの寄稿記事

tamsulosin
Urinary Bladder
Pharmacokinetics
Pediatrics
Population
10 引用 (Scopus)

Usefulness of serum cystatin C to determine the dose of vancomycin in critically ill patients

Suzuki, A., Imanishi, Y., Nakano, S., Niwa, T., Ohmori, T., Shirai, K., Yoshida, S., Furuta, N., Takemura, M., Ito, H., Ieiri, I., Seishima, M., Ogura, S. & Itoh, Y., 7 1 2010, : : Journal of Pharmacy and Pharmacology. 62, 7, p. 901-907 7 p.

研究成果: ジャーナルへの寄稿記事

Cystatin C
Vancomycin
Critical Illness
Creatinine
Serum
2009
10 引用 (Scopus)

Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine-alprazolam interaction in patients with psychosomatic disease

Sugahara, H., Maebara, C., Ohtani, H., Handa, M., Ando, K., Mine, K., Kubo, C., Ieiri, I. & Sawada, Y., 7 1 2009, : : European Journal of Clinical Pharmacology. 65, 7, p. 699-704 6 p.

研究成果: ジャーナルへの寄稿記事

Alprazolam
Fluvoxamine
Cytochrome P-450 CYP2D6
Smoking
Cytochrome P-450 CYP3A
4 引用 (Scopus)

Influence of dosing schedules on toxicity and antitumour effects of combined cisplatin and docetaxel treatment in mice

Kodama, A., To, H., Kinoshita, T., Ieiri, I. & Higuchi, S., 1 1 2009, : : Journal of Pharmacy and Pharmacology. 61, 5, p. 615-621 7 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Cisplatin
Appointments and Schedules
Lewis Lung Carcinoma
Inbred ICR Mouse

Influence of dosing schedules on toxicity and antitumour effects of combined cisplatin and docetaxel treatment in mice.

Kodama, A., To, H., Kinoshita, T., Ieiri, I. & Higuchi, S., 5 1 2009, : : The Journal of pharmacy and pharmacology. 61, 5, p. 615-621 7 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Cisplatin
Appointments and Schedules
Lewis Lung Carcinoma
Inbred ICR Mouse
41 引用 (Scopus)

Life-threatening toxicities in a patient with UGT1A1*6/*28 and SLCO1B1*15/*15 genotypes after irinotecan-based chemotherapy

Takane, H., Kawamoto, K., Sasaki, T., Moriki, K., Moriki, K., Kitano, H., Higuchi, S., Otsubo, K. & Ieiri, I., 5 1 2009, : : Cancer Chemotherapy and Pharmacology. 63, 6, p. 1165-1169 5 p.

研究成果: ジャーナルへの寄稿記事

irinotecan
Chemotherapy
Toxicity
Genotype
Drug Therapy
10 引用 (Scopus)

Novel large-scale deletion (whole Exon 7) in the ABCC2 gene in a patient with the Dubin-Johnson syndrome

Kanda, D., Takagi, H., Kawahara, Y., Yata, Y., Takakusagi, T., Hatanaka, T., Yoshinaga, T., Iesaki, K., Kashiwabara, K., Higuchi, T., Mori, M., Hirota, T., Higuchi, S. & Ieiri, I., 1 1 2009, : : Drug Metabolism and Pharmacokinetics. 24, 5, p. 464-468 5 p.

研究成果: ジャーナルへの寄稿記事

Chronic Idiopathic Jaundice
Constrictive Pericarditis
Exons
Hyperbilirubinemia
Genes
16 引用 (Scopus)

Quantitative population pharmacokinetic analysis of pravastatin using an enterohepatic circulation model combined with pharmacogenomic information on SLCO1B1 and ABCC2 polymorphisms

Ide, T., Sasaki, T., Maeda, K., Higuchi, S., Sugiyama, Y. & Ieiri, I., 11 1 2009, : : Journal of Clinical Pharmacology. 49, 11, p. 1309-1317 9 p.

研究成果: ジャーナルへの寄稿記事

Enterohepatic Circulation
Pravastatin
Pharmacogenetics
Pharmacokinetics
Population
18 引用 (Scopus)

Warfarin-dosing algorithm based on a population pharmacokinetic/ pharmacodynamic model combined with Bayesian forecasting

Sasaki, T., Tabuchi, H., Higuchi, S. & Ieiri, I., 12 2 2009, : : Pharmacogenomics. 10, 8, p. 1257-1266 10 p.

研究成果: ジャーナルへの寄稿記事

Warfarin
International Normalized Ratio
Pharmacokinetics
Population
Prothrombin Time
2008

Clinically applicable pharmacogenomics of anti-cancer drugs

Ieiri, I. & Higuchi, S., 11 1 2008, : : Japanese Journal of Clinical Pharmacology and Therapeutics. 39, 6, p. 233-237 5 p.

研究成果: ジャーナルへの寄稿記事

irinotecan
Pharmacogenetics
ATP-Binding Cassette Transporters
Drug Therapy
Pharmaceutical Preparations
50 引用 (Scopus)

Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea

Tanaka, M., Kobayashi, D., Murakami, Y., Ozaki, N., Suzuki, T., Iwata, N., Haraguchi, K., Ieiri, I., Kinukawa, N., Hosoi, M., Ohtani, H., Sawada, Y. & Mine, K., 3 1 2008, : : International Journal of Neuropsychopharmacology. 11, 2, p. 261-267 7 p.

研究成果: ジャーナルへの寄稿記事

Paroxetine
Serotonin Receptors
Genetic Polymorphisms
Nausea
Genes
119 引用 (Scopus)

Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans

Yamasaki, Y., Ieiri, I., Kusuhara, H., Sasaki, T., Kimura, M., Tabuchi, H., Ando, Y., Irie, S., Ware, J. A., Nakai, Y., Higuchi, S. & Sugiyama, Y., 7 1 2008, : : Clinical Pharmacology and Therapeutics. 84, 1, p. 95-103 9 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Pharmacogenetics
Sulfapyridine
Pharmacokinetics
Breast Neoplasms

Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans

Ieiri, I., Yamasaki, Y., Sasaki, T., Hirota, T., Higuchi, S., Kimura, M., Irie, S., Kusuhara, H. & Sugiyama, Y., 12 1 2008, : : Japanese Pharmacology and Therapeutics. 36, SUPPL. 2, p. 131-134 4 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Pharmacogenetics
Genes
29 引用 (Scopus)

Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism

Suwannakul, S., Ieiri, I., Kimura, M., Kawabata, K., Kusuhara, H., Hirota, T., Irie, S., Sugiyama, Y. & Higuchi, S., 10 1 2008, : : Journal of Human Genetics. 53, 10, p. 899-904 6 p.

研究成果: ジャーナルへの寄稿記事

Pravastatin
Pharmacokinetics
Sample Size
olmesartan
Healthy Volunteers
2007
128 引用 (Scopus)

Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin

Shikata, E., Yamamoto, R., Takane, H., Shigemasa, C., Ikeda, T., Otsubo, K. & Ieiri, I., 2 1 2007, : : Journal of Human Genetics. 52, 2, p. 117-122 6 p.

研究成果: ジャーナルへの寄稿記事

Metformin
Therapeutic Uses
Cations
Genes
5' Flanking Region
33 引用 (Scopus)

Severe toxicities after irinotecan-based chemotherapy in a patient with lung cancer: A homozygote for the SLCO1B1*15 allele

Takane, H., Miyata, M., Burioka, N., Kurai, J., Fukuoka, Y., Suyama, H., Shigeoka, Y., Otsubo, K., Ieiri, I. & Shimizu, E., 10 1 2007, : : Therapeutic Drug Monitoring. 29, 5, p. 666-668 3 p.

研究成果: ジャーナルへの寄稿記事

irinotecan
Homozygote
Lung Neoplasms
Alleles
Drug Therapy
129 引用 (Scopus)

SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers

Ieiri, I., Suwannakul, S., Maeda, K., Uchimaru, H., Hashimoto, K., Kimura, M., Fujino, H., Hirano, M., Kusuhara, H., Irie, S., Higuchi, S. & Sugiyama, Y., 11 1 2007, : : Clinical Pharmacology and Therapeutics. 82, 5, p. 541-547 7 p.

研究成果: ジャーナルへの寄稿記事

Healthy Volunteers
Pharmacokinetics
Alleles
Genetic Polymorphisms
pitavastatin
2006
296 引用 (Scopus)

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

Takahashi, H., Wilkinson, G. R., Nutescu, E. A., Morita, T., Ritchie, M. D., Scordo, M. G., Pengo, V., Barban, M., Padrini, R., Ieiri, I., Otsubo, K., Kashima, T., Kimura, S., Kijima, S. & Echizen, H., 1 1 2006, : : Pharmacogenetics and Genomics. 16, 2, p. 101-110 10 p.

研究成果: ジャーナルへの寄稿記事

Warfarin
African Americans
Population
Prothrombin
Vitamin K Epoxide Reductases
161 引用 (Scopus)

Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

Maeda, K., Ieiri, I., Yasuda, K., Fujino, A., Fujiwara, H., Otsubo, K., Hirano, M., Watanabe, T., Kitamura, Y., Kusuhara, H. & Sugiyama, Y., 5 1 2006, : : Clinical Pharmacology and Therapeutics. 79, 5, p. 427-439 13 p.

研究成果: ジャーナルへの寄稿記事

Valsartan
Pravastatin
Haplotypes
Anions
Pharmacokinetics
80 引用 (Scopus)

Evaluation of in vivo P-glycoprotein function at the blood-brain barrier among MDR1 gene polymorphisms by using 11C-verapamil

Takano, A., Kusuhara, H., Suhara, T., Ieiri, I., Morimoto, T., Lee, Y. J., Maeda, J., Ikoma, Y., Ito, H., Suzuki, K. & Sugiyama, Y., 9 1 2006, : : Journal of Nuclear Medicine. 47, 9, p. 1427-1433 7 p.

研究成果: ジャーナルへの寄稿記事

P-Glycoprotein
Verapamil
Blood-Brain Barrier
Haplotypes
Genes
64 引用 (Scopus)

Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy

Takane, H., Miyata, M., Burioka, N., Shigemasa, C., Shimizu, E., Otsubo, K. & Ieiri, I., 9 1 2006, : : Journal of Human Genetics. 51, 9, p. 822-826 5 p.

研究成果: ジャーナルへの寄稿記事

Pravastatin
Pharmacogenetics
Lipids
Alleles
Apolipoproteins E
2005
224 引用 (Scopus)

Functional assessment of ABCG2 (BRCP) gene polymorphisms to protein expression in human placenta

Kobayashi, D., Ieiri, I., Hirota, T., Takane, H., Maegawa, S., Kigawa, J., Suzuki, H., Nanba, E., Oshimura, M., Terakawa, N., Otsubo, K., Mine, K. & Sugiyama, Y., 1 1 2005, : : Drug Metabolism and Disposition. 33, 1, p. 94-101 8 p.

研究成果: ジャーナルへの寄稿記事

Placenta
Alleles
Allelic Imbalance
Terminator Codon
Genes
24 引用 (Scopus)

Interaction magnitude, pharmacokinetics and pharmacodynamics of ticlopidine in relation to CYP2C19 genotypic status

Ieiri, I., Kimura, M., Irie, S., Urae, A., Otsubo, K. & Ishizaki, T., 1 1 2005, : : Pharmacogenetics and Genomics. 15, 12, p. 851-859 9 p.

研究成果: ジャーナルへの寄稿記事

Ticlopidine
Pharmacokinetics
Omeprazole
Platelet Aggregation
Cytochrome P-450 CYP2C19
2004
39 引用 (Scopus)

5′-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients

Takahashi, H., Ieiri, I., Wilkinson, G. R., Mayo, G., Kashima, T., Kimura, S., Otsubo, K. & Echizen, H., 4 15 2004, : : Blood. 103, 8, p. 3055-3057 3 p.

研究成果: ジャーナルへの寄稿記事

5' Flanking Region
Warfarin
Polymorphism
Metabolism
Linkage Disequilibrium
119 引用 (Scopus)

Association of pharmacokinetic (CY72C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and γ-glutamyl carboxylase) gene variants with warfarin sensitivity

Shikata, E., Ieiri, I., Ishiguro, S., Aono, H., Inoue, K., Koide, T., Ohgi, S. & Otsubo, K., 4 1 2004, : : Blood. 103, 7, p. 2630-2635 6 p.

研究成果: ジャーナルへの寄稿記事

Pharmacodynamics
Factor VII
Pharmacokinetics
Protein S
Prothrombin
94 引用 (Scopus)

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2

Hirouchi, M., Suzuki, H., Itoda, M., Ozawa, S., Sawada, J. I., Ieiri, I., Ohtsubo, K. & Sugiyama, Y., 5 1 2004, : : Pharmaceutical Research. 21, 5, p. 742-748 7 p.

研究成果: ジャーナルへの寄稿記事

Polymorphism
LLC-PK1 Cells
Single Nucleotide Polymorphism
Nucleotides
Membranes
131 引用 (Scopus)

Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C)

Iwai, M., Suzuki, H., Ieiri, I., Otsubo, K. & Sugiyama, Y., 11 1 2004, : : Pharmacogenetics. 14, 11, p. 749-757 9 p.

研究成果: ジャーナルへの寄稿記事

Organic Anion Transporters
Single Nucleotide Polymorphism
Liver
Pravastatin
HEK293 Cells
207 引用 (Scopus)

Functional analysis of SNPs variants of BCRP/ABCG2

Kondo, C., Suzuki, H., Itoda, M., Ozawa, S., Sawada, J. I., Kobayashi, D., Ieiri, I., Mine, K., Ohtsubo, K. & Sugiyama, Y., 10 1 2004, : : Pharmaceutical Research. 21, 10, p. 1895-1903 9 p.

研究成果: ジャーナルへの寄稿記事

Functional analysis
Polymorphism
Single Nucleotide Polymorphism
Nucleotides
Complementary DNA
74 引用 (Scopus)

Haplotype-oriented genetic analysis and functional assessment of promoter variants in the MDR1 (ABCB1) gene

Takane, H., Kobayashi, D., Hirota, T., Kigawa, J., Terakawa, N., Otsubo, K. & Ieiri, I., 12 1 2004, : : Journal of Pharmacology and Experimental Therapeutics. 311, 3, p. 1179-1187 9 p.

研究成果: ジャーナルへの寄稿記事

Genetic Promoter Regions
Haplotypes
Genes
Nucleotides
Multiple Drug Resistance
49 引用 (Scopus)

Influence of common variants in the pharmacokinetic genes (OATP-C, UGT1A1, and MRP2) on serum bilirubin levels in healthy subjects

Ieiri, I., Suzuki, H., Kimura, M., Takane, H., Nishizato, Y., Irie, S., Urae, A., Kawabata, K., Higuchi, S., Otsubo, K. & Sugiyama, Y., 1 1 2004, : : Hepatology Research. 30, 2, p. 91-95 5 p.

研究成果: ジャーナルへの寄稿記事

Bilirubin
Healthy Volunteers
Pharmacokinetics
Serum
Genes

Simultaneous determination of carbamate pesticides in human serum and urine by automatic reversed-phase HPLC combined with on-line column enrichment

Ichinoki, S., Watanabe, S., Matsuida, S., Fujii, Y., Morita, T., Ieiri, I. & Otsubo, K., 7 1 2004, : : bunseki kagaku. 53, 7, p. 705-713 9 p.

研究成果: ジャーナルへの寄稿記事

Carbamates
Pesticides
Recovery
Arylsulfatases
Membranes
2003
15 引用 (Scopus)

A CYP2D6 Phenotype-Genotype Mismatch in Japanese Psychiatric Patients

Ieiri, I., Yamada, S., Seto, K., Morita, T., Kaneda, T., Mamiya, K., Tashiro, N., Higuchi, S. & Otsubo, K., 9 1 2003, : : Pharmacopsychiatry. 36, 5, p. 192-196 5 p.

研究成果: ジャーナルへの寄稿記事

Cytochrome P-450 CYP2D6
Psychiatry
Genotype
Phenotype
Psychotropic Drugs
39 引用 (Scopus)

Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain

Yamada, H., Ishii, K., Ishii, Y., Ieiri, I., Nishio, S., Morioka, T. & Oguri, K., 12 1 2003, : : Journal of Toxicological Sciences. 28, 5, p. 395-401 7 p.

研究成果: ジャーナルへの寄稿記事

Morphine
Analgesics
Brain
Glucuronides
Glucuronosyltransferase

Functional Analysis of SNPs in Human OATP2 (OATP-C/SLC21A6)

Iwai, M., Suzuki, H., Sugiyama, Y., Nishizato, Y., Ieiri, I. & Otsubo, K., 12 1 2003, : : Japanese Pharmacology and Therapeutics. 31, SUPPL. 1

研究成果: ジャーナルへの寄稿記事

Solute Carrier Organic Anion Transporter Family Member 1b1
Single Nucleotide Polymorphism
428 引用 (Scopus)

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics

Nishizato, Y., Ieiri, I., Suzuki, H., Kimura, M., Kawabata, K., Hirota, T., Takane, H., Irie, S., Kusuhara, H., Urasaki, Y., Urae, A., Higuchi, S., Otsubo, K. & Sugiyama, Y., 6 1 2003, : : Clinical Pharmacology and Therapeutics. 73, 6, p. 554-565 12 p.

研究成果: ジャーナルへの寄稿記事

Organic Anion Transporters
Pravastatin
Anions
Pharmacokinetics
Genes