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研究成果 1988 2019

フィルター
評論記事
2019
1 引用 (Scopus)

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Hirota, T., Muraki, S. & Ieiri, I., 4 4 2019, : : Clinical Pharmacokinetics. 58, 4, p. 403-420 18 p.

研究成果: ジャーナルへの寄稿評論記事

Non-Small Cell Lung Carcinoma
Pharmacokinetics
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP3A
2017
3 引用 (Scopus)

Epigenetic regulation of drug transporter expression in human tissues

Hirota, T., Tanaka, T., Takesue, H. & Ieiri, I., 1 2 2017, : : Expert Opinion on Drug Metabolism and Toxicology. 13, 1, p. 19-30 12 p.

研究成果: ジャーナルへの寄稿評論記事

Drug and Narcotic Control
Epigenomics
Tissue
Pharmaceutical Preparations
Genes
2015
25 引用 (Scopus)

Drug-drug interactions that interfere with statin metabolism

Hirota, T. & Ieiri, I., 9 2 2015, : : Expert Opinion on Drug Metabolism and Toxicology. 11, 9, p. 1435-1447 13 p.

研究成果: ジャーナルへの寄稿評論記事

Drug interactions
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Drug Interactions
Metabolism
Pharmaceutical Preparations
1 引用 (Scopus)
Biological Transport
Hypoglycemic Agents
Pharmacokinetics
Kidney
Liver
2014
Osteoporosis
Pharmacokinetics
Pharmaceutical Preparations
Population
Bone Remodeling
2013
12 引用 (Scopus)

Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions

Ono, C., Kikkawa, H., Suzuki, A., Suzuki, M., Yamamoto, Y., Ichikawa, K., Fukae, M. & Ieiri, I., 1 1 2013, : : Pharmacogenomics. 14, 14, p. 1745-1764 20 p.

研究成果: ジャーナルへの寄稿評論記事

Ethnic Groups
Pharmaceutical Preparations
Precision Medicine
Far East
Pharmacokinetics
61 引用 (Scopus)

Impact of genetic polymorphisms in CYP2C9 and CYP2C19 on the pharmacokinetics of clinically used drugs

Hirota, T., Eguchi, S. & Ieiri, I., 1 1 2013, : : Drug Metabolism and Pharmacokinetics. 28, 1, p. 28-37 10 p.

研究成果: ジャーナルへの寄稿評論記事

Genetic Polymorphisms
Pharmacokinetics
Pharmaceutical Preparations
Precision Medicine
Xenobiotics
2012
1 引用 (Scopus)

[Development of evaluation methods for student performance in National Universities: formative assessment and portfolio].

Takiguchi, Y., Arai, K., Ieiri, I., Uejima, E. & Hirata, K., 1 1 2012, : : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 132, 3, p. 365-368 4 p.

研究成果: ジャーナルへの寄稿評論記事

Students
Learning
Information Dissemination
Pharmacies
Community Hospital
21 引用 (Scopus)

Psychotropic drug-drug interactions involving P-glycoprotein

Akamine, Y., Yasui-Furukori, N., Ieiri, I. & Uno, T., 11 1 2012, : : CNS Drugs. 26, 11, p. 959-973 15 p.

研究成果: ジャーナルへの寄稿評論記事

Psychotropic Drugs
P-Glycoprotein
Cytochrome P-450 CYP3A
Drug Interactions
Pharmacokinetics
2009
155 引用 (Scopus)
Pharmacodynamics
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Pharmacokinetics
Genetic Polymorphisms
Polymorphism
5 引用 (Scopus)

Pharmacogenomics: Inter-ethnic and intra-ethnic differences in pharmacokinetic and pharmacodynamic profiles of clinically relevant drugs

Ieiri, I. & Higuchi, S., 2 1 2009, : : Yakugaku Zasshi. 129, 2, p. 231-235 5 p.

研究成果: ジャーナルへの寄稿評論記事

Pharmacogenetics
Pharmacokinetics
Pharmaceutical Preparations
Organic Cation Transporter 1
Pravastatin
2008
22 引用 (Scopus)

Epigenetic regulation of genes encoding drug-metabolizing enzymes and transporters; DNA methylation and other mechanisms

Hirota, T., Takane, H., Higuchi, S. & Ieiri, I., 1 1 2008, : : Current Drug Metabolism. 9, 1, p. 34-38 5 p.

研究成果: ジャーナルへの寄稿評論記事

Gene encoding
DNA Methylation
Epigenomics
Genes
Pharmacodynamics
93 引用 (Scopus)

Polymorphism in human organic cation transporters and metformin action

Takane, H., Shikata, E., Otsubo, K., Higuchi, S. & Ieiri, I., 4 1 2008, : : Pharmacogenomics. 9, 4, p. 415-422 8 p.

研究成果: ジャーナルへの寄稿評論記事

Metformin
Cations
Genetic Polymorphisms
Biguanides
Hypoglycemic Agents
2006
39 引用 (Scopus)

Genetic polymorphisms of drug transporters: Pharmacokinetic and pharmacodynamic consequences in pharmacotherapy

Ieiri, I., Takane, H., Hirota, T., Otsubo, K. & Higuchi, S., 12 1 2006, : : Expert Opinion on Drug Metabolism and Toxicology. 2, 5, p. 651-674 24 p.

研究成果: ジャーナルへの寄稿評論記事

Pharmacodynamics
Drug therapy
Pharmacokinetics
Genetic Polymorphisms
Polymorphism
2005

Pharmacogenetics of drug transporter and its clinical implications

Ieiri, I., 2005, : : Japanese Journal of Clinical Chemistry. 34, 1, p. 5-10 6 p.

研究成果: ジャーナルへの寄稿評論記事

Pharmacogenetics
Pharmaceutical Preparations
2004
131 引用 (Scopus)

The MDR1 (ABCB1) gene polymorphism and its clinical implications

Ieiri, I., Takane, H. & Otsubo, K., 8 2 2004, : : Clinical Pharmacokinetics. 43, 9, p. 553-576 24 p.

研究成果: ジャーナルへの寄稿評論記事

P-Glycoprotein
Pharmaceutical Preparations
Genes
fexofenadine
talinolol
2000
79 引用 (Scopus)

Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single- strand conformation polymorphism analysis

Ieiri, I., Tainaka, H., Morita, T., Hadama, A., Mamiya, K., Hayashibara, M., Ninomiya, H., Ohmori, S., Kitada, M., Tashiro, N., Higuchi, S. & Otsubo, K., 6 1 2000, : : Therapeutic drug monitoring. 22, 3, p. 237-244 8 p.

研究成果: ジャーナルへの寄稿評論記事

Single-Stranded Conformational Polymorphism
Heterozygote
Amino Acids
Oxidoreductases
Diclofenac