Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1998 2019

2017
4 引用 (Scopus)

CD44 variant–dependent regulation of redox balance in EGFR mutation–positive non–small cell lung cancer: A target for treatment

Kawano, Y., Iwama, E., Tsuchihashi, K., Shibahara, D., Harada, T., Tanaka, K., Nagano, O., Saya, H., Nakanishi, Y. & Okamoto, I., 11 1 2017, : : Lung Cancer. 113, p. 72-78 7 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Oxidation-Reduction
Reactive Oxygen Species
Cisplatin
1 引用 (Scopus)

Chronic myelomonocytic leukemia blast crisis in a patient with advanced non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors

Ogata, H., Okamoto, I., Yoshimoto, G., Obara, T., Ijichi, K., Iwama, E., Harada, T., Akashi, K. & Nakanishi, Y., 3 1 2017, : : Respiratory Investigation. 55, 2, p. 181-183 3 p.

研究成果: ジャーナルへの寄稿記事

Leukemia, Myelomonocytic, Chronic
erbB-1 Genes
Blast Crisis
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
14 引用 (Scopus)

Discrepancy in programmed cell death-ligand 1 between primary and metastatic non-small cell lung cancer

Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Katsura, M., Mukae, N., Shoji, F., Okamoto, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., 8 1 2017, : : Anticancer research. 37, 8, p. 4223-4228 6 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Cell Death
Ligands
Radiotherapy
Brain
7 引用 (Scopus)

Marked response to pembrolizumab in a patient with pulmonary pleomorphic carcinoma highly positive for PD-L1

Ikematsu, Y., Yoneshima, Y., Ijichi, K., Tanaka, K., Harada, T., Oda, Y., Nakanishi, Y. & Okamoto, I., 10 1 2017, : : Lung Cancer. 112, p. 230-231 2 p.

研究成果: ジャーナルへの寄稿レター

Carcinoma
Lung
pembrolizumab
1 引用 (Scopus)

Meta-analysis of pemetrexed plus carboplatin doublet safety profile in first-line non-squamous non-small cell lung cancer studies

Okamoto, I., Schuette, W. H. W., Stinchcombe, T. E., Rodrigues-Pereira, J., San Antonio, B., Chen, J., Liu, J., John, W. J. & Zinner, R. G., 5 4 2017, : : Current Medical Research and Opinion. 33, 5, p. 937-941 5 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
Carboplatin
Non-Small Cell Lung Carcinoma
Meta-Analysis
Safety
23 引用 (Scopus)

Monitoring of somatic mutations in circulating cell-free DNA by digital PCR and next-generation sequencing during afatinib treatment in patients with lung adenocarcinoma positive for EGFR activating mutations

Iwama, E., Sakai, K., Azuma, K., Harada, T., Harada, D., Nosaki, K., Hotta, K., Ohyanagi, F., Kurata, T., Fukuhara, T., Akamatsu, H., Goto, K., Shimose, T., Kishimoto, J., Nakanishi, Y., Nishio, K. & Okamoto, I., 1 1 2017, : : Annals of Oncology. 28, 1, p. 136-141 6 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Polymerase Chain Reaction
Mutation
DNA
Alleles
16 引用 (Scopus)

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., 6 1 2017, : : Lung Cancer. 108, p. 75-82 8 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Alleles
Mutation
Protein-Tyrosine Kinases
4 引用 (Scopus)

Phase I study of irinotecan for previously treated lung cancer patients with the UGT1A1*28 or *6 polymorphism: Results of the Lung Oncology Group in Kyushu (LOGIK1004A)

Fukuda, M., Shimada, M., Kitazaki, T., Nagashima, S., Hashiguchi, K., Ebi, N., Takayama, K., Nakanishi, Y., Semba, H., Harada, T., Seto, T., Okamoto, I., Ichinose, Y. & Sugio, K., 1 1 2017, : : Thoracic Cancer. 8, 1, p. 40-45 6 p.

研究成果: ジャーナルへの寄稿記事

irinotecan
Lung Neoplasms
Lung
Maximum Tolerated Dose
Glucuronosyltransferase
7 引用 (Scopus)

Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non-small-cell lung cancer

Otsubo, K., Nosaki, K., Imamura, C. K., Ogata, H., Fujita, A., Sakata, S., Hirai, F., Toyokawa, G., Iwama, E., Harada, T., Seto, T., Takenoyama, M., Ozeki, T., Mushiroda, T., Inada, M., Kishimoto, J., Tsuchihashi, K., Suina, K., Nagano, O., Saya, H. および2人, Nakanishi, Y. & Okamoto, I., 9 1 2017, : : Cancer Science. 108, 9, p. 1843-1849 7 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
Sulfasalazine
Non-Small Cell Lung Carcinoma
Cisplatin
Neoplastic Stem Cells

Severe Aplastic Anemia during Osimertinib Therapy in a Patient with EGFR Tyrosine Kinase Inhibitor–Resistant Non–Small Cell Lung Cancer

Ogata, H., Yamamoto, Y., Harada, T., Nakanishi, Y., Okamoto, I., Iwama, E., Iwama, E., Kato, K. & Oda, Y., 5 1 2017, : : Journal of Thoracic Oncology. 12, 5, p. e46-e47

研究成果: ジャーナルへの寄稿レター

Aplastic Anemia
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Therapeutics
osimertinib
2 引用 (Scopus)

Treatment Rationale and Design for J-AXEL: A Randomized Phase 3 Study Comparing Nab-Paclitaxel With Docetaxel in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer

Yoneshima, Y., Morita, S., Ando, M., Miura, S., Yoshioka, H., Abe, T., Kato, T., Kondo, M., Hosomi, Y., Hotta, K., Yamamoto, N., Kishimoto, J., Nakanishi, Y. & Okamoto, I., 1 1 2017, : : Clinical Lung Cancer. 18, 1, p. 100-103 4 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Non-Small Cell Lung Carcinoma
Nanoparticles
Therapeutics
Disease Progression
3 引用 (Scopus)
6 引用 (Scopus)

Two cases of late-onset secondary adrenal insufficiency after discontinuation of nivolumab

Otsubo, K., Nakatomi, K., Furukawa, R., Ashida, K., Yoneshima, Y., Nakanishi, Y. & Okamoto, I., 12 1 2017, : : Annals of Oncology. 28, 12, p. 3106-3107 2 p.

研究成果: ジャーナルへの寄稿レター

Adrenal Insufficiency
nivolumab
2016
40 引用 (Scopus)

Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib

Yonesaka, K., Hirotani, K., Kawakami, H., Takeda, M., Kaneda, H., Sakai, K., Okamoto, I., Nishio, K., Jänne, P. A. & Nakagawa, K., 2 18 2016, : : Oncogene. 35, 7, p. 878-886 9 p.

研究成果: ジャーナルへの寄稿記事

Neuregulin-1
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Monoclonal Antibodies
Protein-Tyrosine Kinases
31 引用 (Scopus)

Bevacizumab beyond disease progression after first-line treatment with bevacizumab plus chemotherapy in advanced nonsquamous non-small cell lung cancer (West Japan Oncology Group 5910L): An open-label, randomized, phase 2 trial

Takeda, M., Yamanaka, T., Seto, T., Hayashi, H., Azuma, K., Okada, M., Sugawara, S., Daga, H., Hirashima, T., Yonesaka, K., Urata, Y., Murakami, H., Saito, H., Kubo, A., Sawa, T., Miyahara, E., Nogami, N., Nakagawa, K., Nakanishi, Y. & Okamoto, I., 4 1 2016, : : Cancer. 122, 7, p. 1050-1059 10 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Non-Small Cell Lung Carcinoma
Disease Progression
Japan
Drug Therapy
27 引用 (Scopus)

Characteristics and overall survival of EGFR mutation-positive non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors: A retrospective analysis for 1660 Japanese patients

Inoue, A., Yoshida, K., Morita, S., Imamura, F., Seto, T., Okamoto, I., Nakagawa, K., Yamamoto, N., Muto, S. & Fukuoka, M., 1 1 2016, : : Japanese journal of clinical oncology. 46, 5, p. 462-467 6 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Mutation
Survival
5 引用 (Scopus)

Characteristics of smoking patients with lung cancer with emphysematous bullae

Iwama, E., Okamoto, I., Yabuuchi, H., Takayama, K., Harada, T., Matsuo, Y., Tokunaga, S., Baba, E. & Nakanishi, Y., 1 1 2016, : : Journal of Thoracic Oncology. 11, 9, p. 1586-1590 5 p.

研究成果: ジャーナルへの寄稿記事

Blister
Lung Neoplasms
Smoking
Emphysema
Epidermal Growth Factor
71 引用 (Scopus)

Effect of dose adjustment on the safety and efficacy of afatinib for EGFR mutation-positive lung adenocarcinoma: Post hoc analyses of the randomized LUX-Lung 3 and 6 trials

Yang, J. C. H., Sequist, L. V., Zhou, C., Schuler, M., Geater, S. L., Mok, T., Hu, C. P., Yamamoto, N., Feng, J., O'Byrne, K., Lu, S., Hirsh, V., Huang, Y., Sebastian, M., Okamoto, I., Dickgreber, N., Shah, R., Märten, A., Massey, D., Wind, S. および1人, Wu, Y. L., 1 1 2016, : : Annals of Oncology. 27, 11, p. 2103-2110 8 p.

研究成果: ジャーナルへの寄稿記事

Safety
Lung
Mutation
Disease-Free Survival
Non-Small Cell Lung Carcinoma
13 引用 (Scopus)

FGFR gene alterations in lung squamous cell carcinoma are potential targets for the multikinase inhibitor nintedanib

Hibi, M., Kaneda, H., Tanizaki, J., Sakai, K., Togashi, Y., Terashima, M., De Velasco, M. A., Fujita, Y., Banno, E., Nakamura, Y., Takeda, M., Ito, A., Mitsudomi, T., Nakagawa, K., Okamoto, I. & Nishio, K., 11 1 2016, : : Cancer Science. 107, 11, p. 1667-1676 10 p.

研究成果: ジャーナルへの寄稿記事

Fibroblast Growth Factor Receptors
Squamous Cell Carcinoma
Lung
Genes
Cell Line
22 引用 (Scopus)

HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer

Takegawa, N., Yonesaka, K., Sakai, K., Ueda, H., Watanabe, S., Nonagase, Y., Okuno, T., Takeda, M., Maenishi, O., Tsurutani, J., Satoh, T., Okamoto, I., Nishio, K., Tamura, T. & Nakagawa, K., 1 1 2016, : : Oncotarget. 7, 3, p. 3453-3460 8 p.

研究成果: ジャーナルへの寄稿記事

Colorectal Neoplasms
Epidermal Growth Factor Receptor
DNA
Neoplasms
Antibodies
12 引用 (Scopus)

MET-targeted therapy for gastric cancer: the importance of a biomarker-based strategy

Kawakami, H. & Okamoto, I., 7 1 2016, : : Gastric Cancer. 19, 3, p. 687-695 9 p.

研究成果: ジャーナルへの寄稿記事

Stomach Neoplasms
Biomarkers
Hepatocyte Growth Factor
Protein-Tyrosine Kinases
Neoplasms
12 引用 (Scopus)

Phase II study of erlotinib plus tivantinib (ARQ 197) in patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer just after progression on EGFR-TKI, gefitinib or erlotinib

Azuma, K., Hirashima, T., Yamamoto, N., Okamoto, I., Takahashi, T., Nishio, M., Hirata, T., Kubota, K., Kasahara, K., Hida, T., Yoshioka, H., Nakanishi, K., Akinaga, S., Nishio, K., Mitsudomi, T. & Nakagawa, K., 7 1 2016, : : ESMO Open. 1, 4, e000063.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Mutation
Hepatocyte Growth Factor
Disease-Free Survival
14 引用 (Scopus)

Phase II trial of weekly nab-paclitaxel for previously treated advanced non–small cell lung cancer: Kumamoto thoracic oncology study group (KTOSG) trial 1301

Sakata, S., Saeki, S., Okamoto, I., Otsubo, K., Komiya, K., Morinaga, R., Yoneshima, Y., Koga, Y., Enokizu, A., Kishi, H., Hirosako, S., Yamaguchi, E., Aragane, N., Fujii, S., Harada, T., Iwama, E., Semba, H., Nakanishi, Y. & Kohrogi, H., 9 1 2016, : : Lung Cancer. 99, p. 41-45 5 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Thorax
docetaxel
Confidence Intervals
Febrile Neutropenia
50 引用 (Scopus)

Re-biopsy status among non-small cell lung cancer patients in Japan: A retrospective study

Nosaki, K., Satouchi, M., Kurata, T., Yoshida, T., Okamoto, I., Katakami, N., Imamura, F., Tanaka, K., Yamane, Y., Yamamoto, N., Kato, T., Kiura, K., Saka, H., Yoshioka, H., Watanabe, K., Mizuno, K. & Seto, T., 11 1 2016, : : Lung Cancer. 101, p. 1-8 8 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Japan
Retrospective Studies
Biopsy
Epidermal Growth Factor Receptor
2015
52 引用 (Scopus)

Afatinib versus cisplatin plus pemetrexed in Japanese patients with advanced non-small cell lung cancer harboring activating EGFR mutations: Subgroup analysis of LUX-Lung 3

Kato, T., Yoshioka, H., Okamoto, I., Yokoyama, A., Hida, T., Seto, T., Kiura, K., Massey, D., Seki, Y. & Yamamoto, N., 9 1 2015, : : Cancer Science. 106, 9, p. 1202-1211 10 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
Non-Small Cell Lung Carcinoma
Cisplatin
Lung
Mutation
9 引用 (Scopus)

Circulating hepatocyte growth factor is correlated with resistance to cetuximab in metastatic colorectal cancer

Yonesaka, K., Satoh, T., Ueda, S., Yoshida, T., Takeda, M., Shimizu, T., Okamoto, I., Nishio, K., Tamura, T. & Nakagawa, K., 3 1 2015, : : Anticancer Research. 35, 3, p. 1683-1690 8 p.

研究成果: ジャーナルへの寄稿記事

Hepatocyte Growth Factor
Colorectal Neoplasms
Transforming Growth Factors
Epidermal Growth Factor Receptor
Disease-Free Survival

Clinical benefits associated with first line treatment using afatinib

Iwama, E. & Okamoto, I., 10 20 2015, : : Japanese Journal of Lung Cancer. 55, 6, p. 866-870 5 p.

研究成果: ジャーナルへの寄稿評論記事

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Therapeutics
Mutation
Paronychia
6 引用 (Scopus)

Clinical development of nintedanib for advanced non-small-cell lung cancer

Takeda, M., Okamoto, I. & Nakagawa, K., 11 16 2015, : : Therapeutics and Clinical Risk Management. 11, p. 1701-1706 6 p.

研究成果: ジャーナルへの寄稿評論記事

docetaxel
Non-Small Cell Lung Carcinoma
cancer
Cells
Toxicity
7 引用 (Scopus)

Combined analysis of plasma amphiregulin and heregulin predicts response to cetuximab in metastatic colorectal cancer

Yonesaka, K., Takegawa, N., Satoh, T., Ueda, H., Yoshida, T., Takeda, M., Shimizu, T., Chiba, Y., Okamoto, I., Nishio, K., Tamura, T. & Nakagawa, K., 11 1 2015, : : PloS one. 10, 11, e0143132.

研究成果: ジャーナルへの寄稿記事

Neuregulin-1
colorectal neoplasms
Colorectal Neoplasms
Plasmas
Epidermal Growth Factor Receptor
46 引用 (Scopus)

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples

Ishii, H., Azuma, K., Sakai, K., Kawahara, A., Yamada, K., Tokito, T., Okamoto, I., Nishio, K. & Hoshino, T., 1 1 2015, : : Oncotarget. 6, 31, p. 30850-30858 9 p.

研究成果: ジャーナルへの寄稿記事

Plasma Cells
Epidermal Growth Factor Receptor
Drug Resistance
Non-Small Cell Lung Carcinoma
Polymerase Chain Reaction
21 引用 (Scopus)

Heterogeneity of anaplastic lymphoma kinase gene rearrangement in non-small-cell lung carcinomas: A comparative study between small biopsy and excision samples

Abe, H., Kawahara, A., Azuma, K., Taira, T., Takase, Y., Fukumitsu, C., Murata, K., Yamaguchi, T., Akiba, J., Ishii, H., Okamoto, I., Hoshino, T., Takamori, S. & Kage, M., 5 30 2015, : : Journal of Thoracic Oncology. 10, 5, p. 800-805 6 p.

研究成果: ジャーナルへの寄稿記事

Gene Rearrangement
Non-Small Cell Lung Carcinoma
Fluorescence In Situ Hybridization
Biopsy
Immunohistochemistry
18 引用 (Scopus)

Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR

Iwama, E., Takayama, K., Harada, T., Okamoto, I., Ookubo, F., Kishimoto, J., Baba, E., Oda, Y. & Nakanishi, Y., 1 1 2015, : : Oncotarget. 6, 24, p. 20466-20473 8 p.

研究成果: ジャーナルへの寄稿記事

Polymerase Chain Reaction
Mutation
Alleles
Therapeutics
Neoplasms
9 引用 (Scopus)

Hypermethylation of the CpG dinucleotide in epidermal growth factor receptor codon 790: Implications for a mutational hotspot leading to the T790M mutation in non-small-cell lung cancer

Fujii, A., Harada, T., Iwama, E., ota, K., Furuyama, K., Ijichi, K., Okamoto, T., Okamoto, I., Takayama, K. & Nakanishi, Y., 5 1 2015, : : Cancer Genetics. 208, 5, p. 271-278 8 p.

研究成果: ジャーナルへの寄稿記事

5-Methylcytosine
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Codon
Mutation

II. Development and future prospects of the third-generation EGFR-tyrosine kinase inhibitor

Sakata, S., Iwama, E. & Okamoto, I., 8 1 2015, : : Japanese Journal of Cancer and Chemotherapy. 42, 8, p. 935-939 5 p.

研究成果: ジャーナルへの寄稿記事

Protein-Tyrosine Kinases

II. Development and Future Prospects of the Third-Generation EGFR-Tyrosine Kinase Inhibitor

Sakata, S., Iwama, E. & Okamoto, I., 8 1 2015, : : Japanese Journal of Cancer and Chemotherapy. 42, 8, p. 935-939 5 p.

研究成果: ジャーナルへの寄稿記事

Drug Design
Protein Kinase Inhibitors
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
215 引用 (Scopus)

Induction of PD-L1 expression by the EML4-ALK oncoprotein and down stream signaling pathways in non-small cell lung cancer

ota, K., Azuma, K., Kawahara, A., Hattori, S., Iwama, E., Tanizaki, J., Harada, T., Matsumoto, K., Takayama, K., Takamori, S., Kage, M., Hoshino, T., Nakanishi, Y. & Okamoto, I., 9 1 2015, : : Clinical Cancer Research. 21, 17, p. 4014-4021 8 p.

研究成果: ジャーナルへの寄稿記事

Oncogene Proteins
Non-Small Cell Lung Carcinoma
Gene Fusion
Phosphatidylinositol 3-Kinases
Cell Line
4 引用 (Scopus)

Infected complex renal cysts during crizotinib therapy in a patient with non-small cell lung cancer positive for ALK rearrangement

Yoneshima, Y., Okamoto, I., Arimura-Omori, M., Kimura, S., Hidaka-Fujimoto, N., Iwama, E., Harada, T., Takayama, K. & Nakanishi, Y., 4 1 2015, : : Investigational New Drugs. 33, 2, p. 510-512 3 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Cysts
Kidney
Therapeutics
Low Back Pain
2 引用 (Scopus)

Multiple regulatory mechanisms of hepatocyte growth factor expression in malignant cells with a short poly(dA) sequence in the HGF gene promoter

Sakai, K., Takeda, M., Okamoto, I., Nakagawa, K. & Nishio, K., 1 1 2015, : : Oncology Letters. 9, 1, p. 405-410 6 p.

研究成果: ジャーナルへの寄稿記事

Hepatocyte Growth Factor
Genes
Single Nucleotide Polymorphism
Cell Line
Introns
18 引用 (Scopus)

Nicotine induces resistance to erlotinib via cross-talk between α 1 nAChR and EGFR in the non-small cell lung cancer xenograft model

Li, H., Wang, S., Takayama, K., Harada, T., Okamoto, I., Iwama, E., Fujii, A., ota, K., Hidaka, N., Kawano, Y. & Nakanishi, Y., 4 1 2015, : : Lung Cancer. 88, 1, p. 1-8 8 p.

研究成果: ジャーナルへの寄稿記事

Nicotinic Receptors
Nicotine
Heterografts
Non-Small Cell Lung Carcinoma
MAP Kinase Signaling System
16 引用 (Scopus)

Phase i study of amatuximab, a novel monoclonal antibody to mesothelin, in Japanese patients with advanced solid tumors

Fujisaka, Y., Kurata, T., Tanaka, K., Kudo, T., Okamoto, K., Tsurutani, J., Kaneda, H., Okamoto, I., Namiki, M., Kitamura, C. & Nakagawa, K., 4 1 2015, : : Investigational New Drugs. 33, 2, p. 380-388 9 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Maximum Tolerated Dose
Mesothelioma
Neoplasms
Adenocarcinoma
4 引用 (Scopus)

Phase i study of nintedanib in combination with pemetrexed as second-line treatment of Japanese patients with advanced non-small cell lung cancer

Daga, H., Takeda, K., Okada, H., Miyazaki, M., Ueda, S., Kaneda, H., Okamoto, I., Yoh, K., Goto, K., Konishi, K., Sarashina, A., Tanaka, T., Kaiser, R. & Nakagawa, K., 12 1 2015, : : Cancer chemotherapy and pharmacology. 76, 6, p. 1225-1233 9 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
Non-Small Cell Lung Carcinoma
Cells
Maximum Tolerated Dose
Toxicity
78 引用 (Scopus)

Pooled safety analysis of EGFR-TKI treatment for EGFR mutation-positive non-small cell lung cancer

Takeda, M., Okamoto, I. & Nakagawa, K., 4 1 2015, : : Lung Cancer. 88, 1, p. 74-79 6 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Safety
Mutation
15 引用 (Scopus)

Randomized controlled trial comparing docetaxel-cisplatin combination with weekly docetaxel alone in elderly patients with advanced non-small-cell lung cancer: Japan Clinical Oncology Group (JCOG) 0207

Tsukada, H., Yokoyama, A., Goto, K., Shinkai, T., Harada, M., Ando, M., Shibata, T., Ohe, Y., Tamura, T., Saijo, N., Yamamoto, N., Nishiwaki, Y., Kubota, K., Segawa, Y., Isobe, H., Eguchi, H., Yoneda, S., Sakai, H., Sawa, T., Ishiguro, T. および24人, Nakagawa, K., Okamoto, I., Kawahara, M., Atagi, S., Nakano, T., Miyake, M., Kaburaki, T., Fujita, Y., Fujiuchi, S., Kudo, K., Takeda, Y., Hida, T., Senba, H., Fujii, S., Tsukamoto, T., Nagasawa, M., Minato, K., Yoshino, R., Watanabe, K., Kunikane, H., Saito, H., Okuno, M., Ito, M. & Yokota, S., 1 1 2015, : : Japanese journal of clinical oncology. 45, 1, p. 88-95 8 p., hyu176.

研究成果: ジャーナルへの寄稿記事

docetaxel
Medical Oncology
Non-Small Cell Lung Carcinoma
Cisplatin
Japan
10 引用 (Scopus)

Severe acute interstitial lung disease in a patient with anaplastic lymphoma kinase rearrangement-positive non-small cell lung cancer treated with alectinib

Yamamoto, Y., Okamoto, I., Otsubo, K., Iwama, E., Hamada, N., Harada, T., Takayama, K. & Nakanishi, Y., 10 22 2015, : : Investigational New Drugs. 33, 5, p. 1148-1150 3 p.

研究成果: ジャーナルへの寄稿記事

Interstitial Lung Diseases
Non-Small Cell Lung Carcinoma
Tomography
Lymphocytosis
Bronchoalveolar Lavage Fluid
6 引用 (Scopus)

Successful treatment with alectinib after crizotinib-induced esophageal ulceration

Yoneshima, Y., Okamoto, I., Takano, T., Enokizu, A., Iwama, E., Harada, T., Takayama, K. & Nakanishi, Y., 6 1 2015, : : Lung Cancer. 88, 3, p. 349-351 3 p.

研究成果: ジャーナルへの寄稿記事

Therapeutics
Protein-Tyrosine Kinases
crizotinib
CH5424802
Wounds and Injuries
12 引用 (Scopus)

Survival, quality-adjusted survival, and other clinical end points in older advanced non-small-cell lung cancer patients treated with albumin-bound paclitaxel

Langer, C. J., Hirsh, V., Okamoto, I., Lin, F. J., Wan, Y., Whiting, S., Ong, T. J., Renschler, M. F. & Botteman, M. F., 6 30 2015, : : British journal of cancer. 113, 1, p. 20-29 10 p.

研究成果: ジャーナルへの寄稿記事

Carboplatin
Non-Small Cell Lung Carcinoma
Paclitaxel
Survival
Quality of Life
51 引用 (Scopus)

The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer

Hayashi, H., Arao, T., Togashi, Y., Kato, H., Fujita, Y., De Velasco, M. A., Kimura, H., Matsumoto, K., Tanaka, K., Okamoto, I., Ito, A., Yamada, Y., Nakagawa, K. & Nishio, K., 1 8 2015, : : Oncogene. 34, 2, p. 199-208 10 p.

研究成果: ジャーナルへの寄稿記事

Pseudogenes
Stomach Neoplasms
Phenotype
Neoplasms
Cell Line
24 引用 (Scopus)

The pan-HER family tyrosine kinase inhibitor afatinib overcomes HER3 ligand heregulin-mediated resistance to EGFR inhibitors in non-small cell lung cancer

Yonesaka, K., Kudo, K., Nishida, S., Takahama, T., Iwasa, T., Yoshida, T., Tanaka, K., Takeda, M., Kaneda, H., Okamoto, I., Nishio, K. & Nakagawa, K., 1 1 2015, : : Oncotarget. 6, 32, p. 33602-33611 10 p.

研究成果: ジャーナルへの寄稿記事

Neuregulin-1
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Ligands
Phosphorylation
26 引用 (Scopus)

Tolerability of nintedanib (BIBF 1120) in combination with docetaxel: A phase 1 study in japanese patients with previously treated non-small-cell lung cancer

Okamoto, I., Miyazaki, M., Takeda, M., Terashima, M., Azuma, K., Hayashi, H., Kaneda, H., Kurata, T., Tsurutani, J., Seto, T., Hirai, F., Konishi, K., Sarashina, A., Yagi, N., Kaiser, R. & Nakagawa, K., 2 6 2015, : : Journal of Thoracic Oncology. 10, 2, p. 346-352 7 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Body Surface Area
Non-Small Cell Lung Carcinoma
Maximum Tolerated Dose
nintedanib
2014
31 引用 (Scopus)

Addition of bevacizumab enhances antitumor activity of erlotinib against non-small cell lung cancer xenografts depending on VEGF expression

Li, H., Takayama, K., Wang, S., Shiraishi, Y., Gotanda, K., Harada, T., Furuyama, K., Iwama, E., Ieiri, I., Okamoto, I. & Nakanishi, Y., 10 9 2014, : : Cancer chemotherapy and pharmacology. 74, 6, p. 1297-1305 9 p.

研究成果: ジャーナルへの寄稿記事

Heterografts
Non-Small Cell Lung Carcinoma
Vascular Endothelial Growth Factor A
Cells
Tumors