年単位の研究成果
研究成果 2010 2019
2019
12
引用
(Scopus)
A chromatin integration labelling method enables epigenomic profiling with lower input
Harada, A., Maehara, K., Handa, T., Arimura, Y., Nogami, J., Hayashi-Takanaka, Y., Shirahige, K., Kurumizaka, H., Kimura, H. & Ohkawa, Y., 2 1 2019, ： : Nature Cell Biology. 21, 2, p. 287-296 10 p.研究成果: ジャーナルへの寄稿 › 記事
Epigenomics
Chromatin
Chromatin Immunoprecipitation
Histone Code
Immunoprecipitation
Biochemical analysis of nucleosome targeting by Tn5 transposase
Sato, S., Arimura, Y., Kujirai, T., Harada, A., Maehara, K., Nogami, J., Ohkawa, Y. & Kurumizaka, H., 8 1 2019, ： : Open Biology. 9, 8, 190116.研究成果: ジャーナルへの寄稿 › 記事
公開
Nucleosomes
DNA
Tn5 transposase
DNA sequences
Genomics
Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme
Witwicka, H., Nogami, J., Syed, S. A., Maehara, K., Padilla-Benavides, T., Ohkawa, Y. & Imbalzano, A. N., 10 1 2019, ： : Molecular and cellular biology. 39, 19, e00063-19.研究成果: ジャーナルへの寄稿 › 記事
公開
Chromatin Assembly and Disassembly
Calcineurin
Skeletal Muscle
Gene Expression
Enzymes
Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes
Konno, D., Kishida, C., Maehara, K., Ohkawa, Y., Kiyonari, H., Okada, S. & Matsuzaki, F., 8 2019, ： : Development (Cambridge). 146, 15, dev174243.研究成果: ジャーナルへの寄稿 › 記事
公開
Telencephalon
Homeobox Genes
Gene Dosage
Olfactory Bulb
Neurogenesis
Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle
Fukuda, S., Kaneshige, A., Kaji, T., Noguchi, Y. T., Takemoto, Y., Zhang, L., Tsujikawa, K., Kokubo, H., Uezumi, A., Maehara, K., Harada, A., Ohkawa, Y. & Fukada, S. I., 9 2019, ： : eLife. 8, e48284.研究成果: ジャーナルへの寄稿 › 記事
公開
Stem cells
Muscle Cells
Muscle
Stem Cells
Muscles
The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis
Abdalla, M. O. A., Yamamoto, T., Maehara, K., Nogami, J., Ohkawa, Y., Miura, H., Poonperm, R., Hiratani, I., Nakayama, H., Nakao, M. & Saitoh, N., 12 1 2019, ： : Nature communications. 10, 1, 3778.研究成果: ジャーナルへの寄稿 › 記事
公開
estrogens
Untranslated RNA
deprivation
apoptosis
loci
2018
5
引用
(Scopus)
Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence
Takizawa, Y., Tanaka, H., Machida, S., Koyama, M., Maehara, K., Ohkawa, Y., Wade, P. A., Wolf, M. & Kurumizaka, H., 1 1 2018, ： : Open Biology. 8, 3, 170255.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
DNA sequences
DNA
Liver
Transcription Factors
11
引用
(Scopus)
Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells
Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 1 1 2018, ： : Nucleic acids research. 46, 13, p. 6683-6696 14 p.研究成果: ジャーナルへの寄稿 › 記事
Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome
Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration
Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., 12 1 2018, ： : Nature communications. 9, 1, 1400.研究成果: ジャーナルへの寄稿 › 記事
skeletal muscle
chromatin
Nucleosomes
regeneration
Histones
5
引用
(Scopus)
Sensitive detection of fluorescence in western blotting by merging images
Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 2018, ： : PloS one. 13, 1, e0191532.研究成果: ジャーナルへの寄稿 › 記事
Merging
Western blotting
Fluorescence
Western Blotting
fluorescence
2017
9
引用
(Scopus)
Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells
Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, ： : Nucleic acids research. 45, 15, p. 8758-8772 15 p.研究成果: ジャーナルへの寄稿 › 記事
DNA Helicases
Embryonic Stem Cells
Chromatin
Gene Expression
Histones
5
引用
(Scopus)
Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 25 2017, ： : Biochemistry. 56, 16, p. 2184-2196 13 p.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Histones
Crystal structure
Epigenomics
Thermodynamic stability
24
引用
(Scopus)
Crystal structure of the overlapping dinucleosome composed of hexasome and octasome
Kato, D., Osakabe, A., Arimura, Y., Mizukami, Y., Horikoshi, N., Saikusa, K., Akashi, S., Nishimura, Y., Park, S. Y., Nogami, J., Maehara, K., Ohkawa, Y., Matsumoto, A., Kono, H., Inoue, R., Sugiyama, M. & Kurumizaka, H., 4 14 2017, ： : Science. 356, 6334, p. 205-208 4 p., 356.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Chromatin Assembly and Disassembly
Histones
DNA
Base Pairing
Erratum: Structure and function of human histone H3.Y nucleosome (Nucleic acids research (2016) 44 13 (6127-6141))
Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 7 2017, ： : Nucleic acids research. 45, 6, 1 p.研究成果: ジャーナルへの寄稿 › コメント/討論
Nucleosomes
Histones
Nucleic Acids
Research
23
引用
(Scopus)
Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis
Ueda, J., Harada, A., Urahama, T., Machida, S., Maehara, K., Hada, M., Makino, Y., Nogami, J., Horikoshi, N., Osakabe, A., Taguchi, H., Tanaka, H., Tachiwana, H., Yao, T., Yamada, M., Iwamoto, T., Isotani, A., Ikawa, M., Tachibana, T., Okada, Y. および4人, , 1 17 2017, ： : Cell Reports. 18, 3, p. 593-600 8 p.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Essential Genes
Spermatogenesis
Germ Cells
Histones
11
引用
(Scopus)
The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation
Kudou, K., Komatsu, T., Nogami, J., Maehara, K., Harada, A., Saeki, H., Oki, E., Maehara, Y. & Ohkawa, Y., 1 1 2017, ： : Open Biology. 7, 9, 170119.研究成果: ジャーナルへの寄稿 › 記事
Myoblasts
Methyltransferases
Muscle
Skeletal Muscle
Maintenance
2
引用
(Scopus)
Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms
Nakamura, T., Murakami, K., Tada, H., Uehara, Y., Nogami, J., Maehara, K., Ohkawa, Y., Saitoh, H., Nishitani, H., Ono, T., Nishi, R., Yokoi, M., Sakai, W. & Sugasawa, K., 4 1 2017, ： : Genes to Cells. 22, 4, p. 392-405 14 p.研究成果: ジャーナルへの寄稿 › 記事
Thymine DNA Glycosylase
DNA Repair
DNA Damage
Gene Expression
Ultraviolet Rays
2016
15
引用
(Scopus)
Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2
Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., 3 2016, ： : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.研究成果: ジャーナルへの寄稿 › 記事
Histone Code
Endogenous Retroviruses
Stem cells
Histones
Clustered Regularly Interspaced Short Palindromic Repeats
5
引用
(Scopus)
Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing
Kobayashi, W., Takaku, M., Machida, S., Tachiwana, H., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 4 7 2016, ： : Scientific reports. 6, 24228.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Chromatin
Recombinases
Homologous Recombination
DNA
14
引用
(Scopus)
Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes
Oka, M., Mura, S., Yamada, K., Sangel, P., Hirata, S., Maehara, K., Kawakami, K., Tachibana, T., Ohkawa, Y., Kimura, H. & Yoneda, Y., 1 7 2016, ： : eLife. 5, JANUARY2016, e09540.研究成果: ジャーナルへの寄稿 › 記事
Homeobox Genes
Chromatin
Fusion reactions
Genes
Stem cells
4
引用
(Scopus)
Exploration of nucleosome positioning patterns in transcription factor function
Maehara, K. & Ohkawa, Y., 1 21 2016, ： : Scientific reports. 6, 19620.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Transcription Factors
Chromatin
Gene Expression
DNA-Directed RNA Polymerases
18
引用
(Scopus)
Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis
Urahama, T., Harada, A., Maehara, K., Horikoshi, N., Sato, K., Sato, Y., Shiraishi, K., Sugino, N., Osakabe, A., Tachiwana, H., Kagawa, W., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 1 15 2016, ： : Epigenetics and Chromatin. 9, 1, 51.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Transcription Initiation Site
Histones
Testis
Seminiferous Tubules
12
引用
(Scopus)
Histone H4 lysine 20 acetylation is associated with gene repression in human cells
Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H. & Isaka, Y., 4 11 2016, ： : Scientific reports. 6, 24318.研究成果: ジャーナルへの寄稿 › 記事
Acetylation
Histones
Lysine
Genes
Transcription Initiation Site
3
引用
(Scopus)
Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas
Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., 10 2016, ： : PloS one. 11, 10, e0165473.研究成果: ジャーナルへの寄稿 › 記事
immunoglobulin genes
Immunoglobulin Genes
hybridomas
Hybridomas
Immunoglobulins
14
引用
(Scopus)
Structure and function of human histone H3.Y nucleosome
Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 7 27 2016, ： : Nucleic acids research. 44, 13, p. 6127-6141 15 p.研究成果: ジャーナルへの寄稿 › 記事
Nucleosomes
Histones
Transcription Initiation Site
DNA
Primates
2015
25
引用
(Scopus)
A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation
Tomita, S., Abdalla, M. O. A., Fujiwara, S., Matsumori, H., Maehara, K., Ohkawa, Y., Iwase, H., Saitoh, N. & Nakao, M., 4 29 2015, ： : Nature communications. 6, 6966.研究成果: ジャーナルへの寄稿 › 記事
Untranslated RNA
loci
breast
estrogens
cancer
7
引用
(Scopus)
Agplus: A rapid and flexible tool for aggregation plots
Maehara, K. & Ohkawa, Y., 7 31 2015, ： : Bioinformatics. 31, 18, p. 3046-3047 2 p.研究成果: ジャーナルへの寄稿 › 記事
Nucleic Acid Regulatory Sequences
Transcription Initiation Site
Aggregation
Agglomeration
Transcription
19
引用
(Scopus)
Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture
Sugimoto, N., Maehara, K., Yoshida, K., Yasukouchi, S., Osano, S., Watanabe, S., Aizawa, M., Yugawa, T., Kiyono, T., Kurumizaka, H., Ohkawa, Y. & Fujita, M., 1 1 2015, ： : Nucleic acids research. 43, 12, p. 5898-5911 14 p.研究成果: ジャーナルへの寄稿 › 記事
Histones
Chromatin
Glutamic Acid
Carrier Proteins
Replication Origin
20
引用
(Scopus)
Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies
Hayashi-Takanaka, Y., Maehara, K., Harada, A., Umehara, T., Yokoyama, S., Obuse, C., Ohkawa, Y., Nozaki, N. & Kimura, H., 12 1 2015, ： : Chromosome Research. 23, 4, p. 753-766 14 p.研究成果: ジャーナルへの寄稿 › 記事
Histone Code
Acetylation
Histones
Monoclonal Antibodies
Epigenomics
18
引用
(Scopus)
Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle
Harada, A., Maehara, K., Sato, Y., Konno, D., Tachibana, T., Kimura, H. & Ohkawa, Y., 1 30 2015, ： : Nucleic acids research. 43, 2, p. 775-786 12 p.研究成果: ジャーナルへの寄稿 › 記事
Histones
Skeletal Muscle
Genes
Histone Code
Nucleic Acid Regulatory Sequences
10
引用
(Scopus)
Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA
Osakabe, A., Adachi, F., Arimura, Y., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 10 7 2015, ： : Open Biology. 5, 10, 150128.研究成果: ジャーナルへの寄稿 › 記事
Satellite DNA
Nucleosomes
DNA Methylation
Heterochromatin
DNA
18
引用
(Scopus)
Tissue-specific expression of histone H3 variants diversified after species separation
Maehara, K., Harada, A., Sato, Y., Matsumoto, M., Nakayama, K. I., Kimura, H. & Ohkawa, Y., 9 17 2015, ： : Epigenetics and Chromatin. 8, 1, 35.研究成果: ジャーナルへの寄稿 › 記事
Histones
Chromatin
Pseudogenes
Genome
Genes
2014
Erratum: Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO (Stem Cell Reports (2014) 2 (910-924))
Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y. & Yamagata, K., 7 8 2014, ： : Stem Cell Reports. 3, 1, 1 p.研究成果: ジャーナルへの寄稿 › コメント/討論
Heterochromatin
DNA Methylation
Stem Cells
22
引用
(Scopus)
Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, methylRO
Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y. & Yamagata, K., 6 3 2014, ： : Stem Cell Reports. 2, 6, p. 910-924 15 p.研究成果: ジャーナルへの寄稿 › 記事
Heterochromatin
DNA Methylation
Developmental Biology
Differentiation Antigens
Gene Silencing
110
引用
(Scopus)
Regulation of RNA polymerase II activation by histone acetylation in single living cells
Stasevich, T. J., Hayashi-Takanaka, Y., Sato, Y., Maehara, K., Ohkawa, Y., Sakata-Sogawa, K., Tokunaga, M., Nagase, T., Nozaki, N., McNally, J. G. & Kimura, H., 12 11 2014, ： : Nature. 516, 7530, p. 272-275 4 p.研究成果: ジャーナルへの寄稿 › 記事
Histone Code
RNA Polymerase II
Acetylation
Histones
Single-Cell Analysis
14
引用
(Scopus)
SraTailor: Graphical user interface software for processing and visualizing ChIP-seq data
Oki, S., Maehara, K., Ohkawa, Y. & Meno, C., 12 1 2014, ： : Genes to Cells. 19, 12, p. 919-926 8 p.研究成果: ジャーナルへの寄稿 › 記事
Software
High-Throughput Nucleotide Sequencing
Chromatin Immunoprecipitation
DNA Sequence Analysis
Language
2013
7
引用
(Scopus)
A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples
Maehara, K., Odawara, J., Harada, A., Yoshimi, T., Nagao, K., Obuse, C., Akashi, K., Tachibana, T., Sakata, T. & Ohkawa, Y., 1 1 2013, ： : Nucleic acids research. 41, 1, p. 54-62 9 p.研究成果: ジャーナルへの寄稿 › 記事
Encyclopedias
Chromatin Immunoprecipitation
RNA Polymerase III
RNA Polymerase II
DNA
31
引用
(Scopus)
Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I
Katahira, J., Okuzaki, D., Inoue, H., Yoneda, Y., Maehara, K. & Ohkawa, Y., 8 1 2013, ： : Nucleic acids research. 41, 14, p. 7060-7072 13 p.研究成果: ジャーナルへの寄稿 › 記事
Polyadenylation
Genes
Messenger RNA
Cell Nucleus Active Transport
Chromatin Immunoprecipitation
2011
20
引用
(Scopus)
The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach
Odawara, J., Harada, A., Yoshimi, T., Maehara, K., Tachibana, T., Okada, S., Akashi, K. & Ohkawa, Y., 10 20 2011, ： : BMC Genomics. 12, 516.研究成果: ジャーナルへの寄稿 › 記事
RNA Polymerase II
Phosphorylation
Genome
Messenger RNA
Genes
2010
絶対正則なテンソルの同値性について (日本計算機統計学会第24回シンポジウム論文集) -- (セッション1B)
前原一満 & 坂田年男, 11 11 2010, ： : 日本計算機統計学会シンポジウム論文集. 24, p. 37-40 4 p.研究成果: ジャーナルへの寄稿 › 記事