年単位の研究成果
研究成果
2020
Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input
Handa, T., Harada, A., Maehara, K., Sato, S., Nakao, M., Goto, N., Kurumizaka, H., Ohkawa, Y. & Kimura, H., 2020, (受理済み/印刷中) ： : Nature Protocols.研究成果: Contribution to journal › Article
2019
A chromatin integration labelling method enables epigenomic profiling with lower input
Harada, A., Maehara, K., Handa, T., Arimura, Y., Nogami, J., Hayashi-Takanaka, Y., Shirahige, K., Kurumizaka, H., Kimura, H. & Ohkawa, Y., 2 1 2019, ： : Nature Cell Biology. 21, 2, p. 287-296 10 p.研究成果: Contribution to journal › Article
23
引用
（Scopus）
Biochemical analysis of nucleosome targeting by Tn5 transposase
Sato, S., Arimura, Y., Kujirai, T., Harada, A., Maehara, K., Nogami, J., Ohkawa, Y. & Kurumizaka, H., 8 1 2019, ： : Open Biology. 9, 8, 190116.研究成果: Contribution to journal › Article
公開
1
引用
（Scopus）
Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme
Witwicka, H., Nogami, J., Syed, S. A., Maehara, K., Padilla-Benavides, T., Ohkawa, Y. & Imbalzano, A. N., 10 1 2019, ： : Molecular and cellular biology. 39, 19, e00063-19.研究成果: Contribution to journal › Article
公開
2
引用
（Scopus）
Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells
Oka, M., Mura, S., Otani, M., Miyamoto, Y., Nogami, J., Maehara, K., Harada, A., Tachibana, T., Yoneda, Y. & Ohkawa, Y., 11 2019, ： : eLife. 8, e46667.研究成果: Contribution to journal › Article
公開
2
引用
（Scopus）
Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes
Konno, D., Kishida, C., Maehara, K., Ohkawa, Y., Kiyonari, H., Okada, S. & Matsuzaki, F., 8 2019, ： : Development (Cambridge). 146, 15, dev174243.研究成果: Contribution to journal › Article
公開
2
引用
（Scopus）
Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle
Fukuda, S., Kaneshige, A., Kaji, T., Noguchi, Y. T., Takemoto, Y., Zhang, L., Tsujikawa, K., Kokubo, H., Uezumi, A., Maehara, K., Harada, A., Ohkawa, Y. & Fukada, S. I., 9 2019, ： : eLife. 8, e48284.研究成果: Contribution to journal › Article
公開
4
引用
（Scopus）
The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis
Abdalla, M. O. A., Yamamoto, T., Maehara, K., Nogami, J., Ohkawa, Y., Miura, H., Poonperm, R., Hiratani, I., Nakayama, H., Nakao, M. & Saitoh, N., 12 1 2019, ： : Nature communications. 10, 1, 3778.研究成果: Contribution to journal › Article
公開
6
引用
（Scopus）
2018
Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence
Takizawa, Y., Tanaka, H., Machida, S., Koyama, M., Maehara, K., Ohkawa, Y., Wade, P. A., Wolf, M. & Kurumizaka, H., 2018, ： : Open Biology. 8, 3, 170255.研究成果: Contribution to journal › Article
8
引用
（Scopus）
Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells
Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 2018, ： : Nucleic acids research. 46, 13, p. 6683-6696 14 p.研究成果: Contribution to journal › Article
15
引用
（Scopus）
Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration
Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., 12 1 2018, ： : Nature communications. 9, 1, 1400.研究成果: Contribution to journal › Article
2
引用
（Scopus）
Sensitive detection of fluorescence in western blotting by merging images
Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 2018, ： : PloS one. 13, 1, e0191532.研究成果: Contribution to journal › Article
6
引用
（Scopus）
2017
Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells
Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, ： : Nucleic acids research. 45, 15, p. 8758-8772 15 p.研究成果: Contribution to journal › Article
11
引用
（Scopus）
Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 25 2017, ： : Biochemistry. 56, 16, p. 2184-2196 13 p.研究成果: Contribution to journal › Article
6
引用
（Scopus）
Crystal structure of the overlapping dinucleosome composed of hexasome and octasome
Kato, D., Osakabe, A., Arimura, Y., Mizukami, Y., Horikoshi, N., Saikusa, K., Akashi, S., Nishimura, Y., Park, S. Y., Nogami, J., Maehara, K., Ohkawa, Y., Matsumoto, A., Kono, H., Inoue, R., Sugiyama, M. & Kurumizaka, H., 4 14 2017, ： : Science. 356, 6334, p. 205-208 4 p., 356.研究成果: Contribution to journal › Article
31
引用
（Scopus）
Erratum: Structure and function of human histone H3.Y nucleosome (Nucleic acids research (2016) 44 13 (6127-6141))
Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 7 2017, ： : Nucleic acids research. 45, 6, p. 3612 1 p.研究成果: Contribution to journal › Comment/debate
1
引用
（Scopus）
Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis
Ueda, J., Harada, A., Urahama, T., Machida, S., Maehara, K., Hada, M., Makino, Y., Nogami, J., Horikoshi, N., Osakabe, A., Taguchi, H., Tanaka, H., Tachiwana, H., Yao, T., Yamada, M., Iwamoto, T., Isotani, A., Ikawa, M., Tachibana, T., Okada, Y. および4人, , 1 17 2017, ： : Cell Reports. 18, 3, p. 593-600 8 p.研究成果: Contribution to journal › Article
30
引用
（Scopus）
The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation
Kudou, K., Komatsu, T., Nogami, J., Maehara, K., Harada, A., Saeki, H., Oki, E., Maehara, Y. & Ohkawa, Y., 2017, ： : Open Biology. 7, 9, 170119.研究成果: Contribution to journal › Article
12
引用
（Scopus）
Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms
Nakamura, T., Murakami, K., Tada, H., Uehara, Y., Nogami, J., Maehara, K., Ohkawa, Y., Saitoh, H., Nishitani, H., Ono, T., Nishi, R., Yokoi, M., Sakai, W. & Sugasawa, K., 4 1 2017, ： : Genes to Cells. 22, 4, p. 392-405 14 p.研究成果: Contribution to journal › Article
2
引用
（Scopus）
2016
Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2
Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., 3 2016, ： : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.研究成果: Contribution to journal › Article
16
引用
（Scopus）
Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing
Kobayashi, W., Takaku, M., Machida, S., Tachiwana, H., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 4 7 2016, ： : Scientific reports. 6, 24228.研究成果: Contribution to journal › Article
7
引用
（Scopus）
Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes
Oka, M., Mura, S., Yamada, K., Sangel, P., Hirata, S., Maehara, K., Kawakami, K., Tachibana, T., Ohkawa, Y., Kimura, H. & Yoneda, Y., 1 7 2016, ： : eLife. 5, JANUARY2016, e09540.研究成果: Contribution to journal › Article
18
引用
（Scopus）
Exploration of nucleosome positioning patterns in transcription factor function
Maehara, K. & Ohkawa, Y., 1 21 2016, ： : Scientific reports. 6, 19620.研究成果: Contribution to journal › Article
4
引用
（Scopus）
Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis
Urahama, T., Harada, A., Maehara, K., Horikoshi, N., Sato, K., Sato, Y., Shiraishi, K., Sugino, N., Osakabe, A., Tachiwana, H., Kagawa, W., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 1 15 2016, ： : Epigenetics and Chromatin. 9, 1, 51.研究成果: Contribution to journal › Article
23
引用
（Scopus）
Histone H4 lysine 20 acetylation is associated with gene repression in human cells
Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H. & Isaka, Y., 4 11 2016, ： : Scientific reports. 6, 24318.研究成果: Contribution to journal › Article
16
引用
（Scopus）
Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas
Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., 10 2016, ： : PloS one. 11, 10, e0165473.研究成果: Contribution to journal › Article
3
引用
（Scopus）
Structure and function of human histone H3.Y nucleosome
Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 7 27 2016, ： : Nucleic acids research. 44, 13, p. 6127-6141 15 p.研究成果: Contribution to journal › Article
18
引用
（Scopus）
2015
A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation
Tomita, S., Abdalla, M. O. A., Fujiwara, S., Matsumori, H., Maehara, K., Ohkawa, Y., Iwase, H., Saitoh, N. & Nakao, M., 4 29 2015, ： : Nature communications. 6, 6966.研究成果: Contribution to journal › Article
34
引用
（Scopus）
Agplus: A rapid and flexible tool for aggregation plots
Maehara, K. & Ohkawa, Y., 7 31 2015, ： : Bioinformatics. 31, 18, p. 3046-3047 2 p.研究成果: Contribution to journal › Article
9
引用
（Scopus）
Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture
Sugimoto, N., Maehara, K., Yoshida, K., Yasukouchi, S., Osano, S., Watanabe, S., Aizawa, M., Yugawa, T., Kiyono, T., Kurumizaka, H., Ohkawa, Y. & Fujita, M., 2015, ： : Nucleic acids research. 43, 12, p. 5898-5911 14 p.研究成果: Contribution to journal › Article
24
引用
（Scopus）
Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies
Hayashi-Takanaka, Y., Maehara, K., Harada, A., Umehara, T., Yokoyama, S., Obuse, C., Ohkawa, Y., Nozaki, N. & Kimura, H., 12 1 2015, ： : Chromosome Research. 23, 4, p. 753-766 14 p.研究成果: Contribution to journal › Article
20
引用
（Scopus）
Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle
Harada, A., Maehara, K., Sato, Y., Konno, D., Tachibana, T., Kimura, H. & Ohkawa, Y., 1 30 2015, ： : Nucleic acids research. 43, 2, p. 775-786 12 p.研究成果: Contribution to journal › Article
23
引用
（Scopus）
Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA
Osakabe, A., Adachi, F., Arimura, Y., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 10 7 2015, ： : Open Biology. 5, 10, 150128.研究成果: Contribution to journal › Article
12
引用
（Scopus）
Tissue-specific expression of histone H3 variants diversified after species separation
Maehara, K., Harada, A., Sato, Y., Matsumoto, M., Nakayama, K. I., Kimura, H. & Ohkawa, Y., 9 17 2015, ： : Epigenetics and Chromatin. 8, 1, 35.研究成果: Contribution to journal › Article
21
引用
（Scopus）
2014
Erratum: Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO (Stem Cell Reports (2014) 2 (910-924))
Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y. & Yamagata, K., 7 8 2014, ： : Stem Cell Reports. 3, 1, p. 216 1 p.研究成果: Contribution to journal › Comment/debate
Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, methylRO
Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y. & Yamagata, K., 6 3 2014, ： : Stem Cell Reports. 2, 6, p. 910-924 15 p.研究成果: Contribution to journal › Article
26
引用
（Scopus）
Regulation of RNA polymerase II activation by histone acetylation in single living cells
Stasevich, T. J., Hayashi-Takanaka, Y., Sato, Y., Maehara, K., Ohkawa, Y., Sakata-Sogawa, K., Tokunaga, M., Nagase, T., Nozaki, N., McNally, J. G. & Kimura, H., 12 11 2014, ： : Nature. 516, 7530, p. 272-275 4 p.研究成果: Contribution to journal › Article
117
引用
（Scopus）
SraTailor: Graphical user interface software for processing and visualizing ChIP-seq data
Oki, S., Maehara, K., Ohkawa, Y. & Meno, C., 12 1 2014, ： : Genes to Cells. 19, 12, p. 919-926 8 p.研究成果: Contribution to journal › Article
14
引用
（Scopus）
2013
A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples
Maehara, K., Odawara, J., Harada, A., Yoshimi, T., Nagao, K., Obuse, C., Akashi, K., Tachibana, T., Sakata, T. & Ohkawa, Y., 1 2013, ： : Nucleic acids research. 41, 1, p. 54-62 9 p.研究成果: Contribution to journal › Article
7
引用
（Scopus）
Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I
Katahira, J., Okuzaki, D., Inoue, H., Yoneda, Y., Maehara, K. & Ohkawa, Y., 8 2013, ： : Nucleic acids research. 41, 14, p. 7060-7072 13 p.研究成果: Contribution to journal › Article
35
引用
（Scopus）
2011
The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach
Odawara, J., Harada, A., Yoshimi, T., Maehara, K., Tachibana, T., Okada, S., Akashi, K. & Ohkawa, Y., 10 20 2011, ： : BMC genomics. 12, 516.研究成果: Contribution to journal › Article
25
引用
（Scopus）
2010
絶対正則なテンソルの同値性について (日本計算機統計学会第24回シンポジウム論文集) -- (セッション1B)
前原一満 & 坂田年男, 11 11 2010, ： : 日本計算機統計学会シンポジウム論文集. 24, p. 37-40 4 p.研究成果: Contribution to journal › Article