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研究成果

  • 658 引用
  • 17 h指数
  • 40 Article
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Article

A chromatin integration labelling method enables epigenomic profiling with lower input

Harada, A., Maehara, K., Handa, T., Arimura, Y., Nogami, J., Hayashi-Takanaka, Y., Shirahige, K., Kurumizaka, H., Kimura, H. & Ohkawa, Y., 2 1 2019, : : Nature Cell Biology. 21, 2, p. 287-296 10 p.

研究成果: Contribution to journalArticle

24 引用 (Scopus)

A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation

Tomita, S., Abdalla, M. O. A., Fujiwara, S., Matsumori, H., Maehara, K., Ohkawa, Y., Iwase, H., Saitoh, N. & Nakao, M., 4 29 2015, : : Nature communications. 6, 6966.

研究成果: Contribution to journalArticle

34 引用 (Scopus)

A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples

Maehara, K., Odawara, J., Harada, A., Yoshimi, T., Nagao, K., Obuse, C., Akashi, K., Tachibana, T., Sakata, T. & Ohkawa, Y., 1 2013, : : Nucleic acids research. 41, 1, p. 54-62 9 p.

研究成果: Contribution to journalArticle

7 引用 (Scopus)

Agplus: A rapid and flexible tool for aggregation plots

Maehara, K. & Ohkawa, Y., 7 31 2015, : : Bioinformatics. 31, 18, p. 3046-3047 2 p.

研究成果: Contribution to journalArticle

9 引用 (Scopus)

Biochemical analysis of nucleosome targeting by Tn5 transposase

Sato, S., Arimura, Y., Kujirai, T., Harada, A., Maehara, K., Nogami, J., Ohkawa, Y. & Kurumizaka, H., 8 1 2019, : : Open Biology. 9, 8, 190116.

研究成果: Contribution to journalArticle

公開
1 引用 (Scopus)
公開
3 引用 (Scopus)

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

Sugimoto, N., Maehara, K., Yoshida, K., Yasukouchi, S., Osano, S., Watanabe, S., Aizawa, M., Yugawa, T., Kiyono, T., Kurumizaka, H., Ohkawa, Y. & Fujita, M., 2015, : : Nucleic acids research. 43, 12, p. 5898-5911 14 p.

研究成果: Contribution to journalArticle

24 引用 (Scopus)

Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, : : Nucleic acids research. 45, 15, p. 8758-8772 15 p.

研究成果: Contribution to journalArticle

11 引用 (Scopus)

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., 3 2016, : : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

研究成果: Contribution to journalArticle

16 引用 (Scopus)

Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing

Kobayashi, W., Takaku, M., Machida, S., Tachiwana, H., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 4 7 2016, : : Scientific reports. 6, 24228.

研究成果: Contribution to journalArticle

7 引用 (Scopus)

Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells

Oka, M., Mura, S., Otani, M., Miyamoto, Y., Nogami, J., Maehara, K., Harada, A., Tachibana, T., Yoneda, Y. & Ohkawa, Y., 11 2019, : : eLife. 8, e46667.

研究成果: Contribution to journalArticle

公開
2 引用 (Scopus)

Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input

Handa, T., Harada, A., Maehara, K., Sato, S., Nakao, M., Goto, N., Kurumizaka, H., Ohkawa, Y. & Kimura, H., 10 1 2020, : : Nature Protocols. 15, 10, p. 3334-3360 27 p.

研究成果: Contribution to journalArticle

Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes

Oka, M., Mura, S., Yamada, K., Sangel, P., Hirata, S., Maehara, K., Kawakami, K., Tachibana, T., Ohkawa, Y., Kimura, H. & Yoneda, Y., 1 7 2016, : : eLife. 5, JANUARY2016, e09540.

研究成果: Contribution to journalArticle

18 引用 (Scopus)

Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence

Takizawa, Y., Tanaka, H., Machida, S., Koyama, M., Maehara, K., Ohkawa, Y., Wade, P. A., Wolf, M. & Kurumizaka, H., 2018, : : Open Biology. 8, 3, 170255.

研究成果: Contribution to journalArticle

9 引用 (Scopus)

Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8

Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 25 2017, : : Biochemistry. 56, 16, p. 2184-2196 13 p.

研究成果: Contribution to journalArticle

6 引用 (Scopus)

Crystal structure of the overlapping dinucleosome composed of hexasome and octasome

Kato, D., Osakabe, A., Arimura, Y., Mizukami, Y., Horikoshi, N., Saikusa, K., Akashi, S., Nishimura, Y., Park, S. Y., Nogami, J., Maehara, K., Ohkawa, Y., Matsumoto, A., Kono, H., Inoue, R., Sugiyama, M. & Kurumizaka, H., 4 14 2017, : : Science. 356, 6334, p. 205-208 4 p., 356.

研究成果: Contribution to journalArticle

31 引用 (Scopus)

Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies

Hayashi-Takanaka, Y., Maehara, K., Harada, A., Umehara, T., Yokoyama, S., Obuse, C., Ohkawa, Y., Nozaki, N. & Kimura, H., 12 1 2015, : : Chromosome Research. 23, 4, p. 753-766 14 p.

研究成果: Contribution to journalArticle

22 引用 (Scopus)

Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes

Konno, D., Kishida, C., Maehara, K., Ohkawa, Y., Kiyonari, H., Okada, S. & Matsuzaki, F., 8 2019, : : Development (Cambridge). 146, 15, dev174243.

研究成果: Contribution to journalArticle

公開
2 引用 (Scopus)

Exploration of nucleosome positioning patterns in transcription factor function

Maehara, K. & Ohkawa, Y., 1 21 2016, : : Scientific reports. 6, 19620.

研究成果: Contribution to journalArticle

4 引用 (Scopus)
17 引用 (Scopus)

Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, methylRO

Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y. & Yamagata, K., 6 3 2014, : : Stem Cell Reports. 2, 6, p. 910-924 15 p.

研究成果: Contribution to journalArticle

26 引用 (Scopus)

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., 12 1 2018, : : Nature communications. 9, 1, 1400.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis

Urahama, T., Harada, A., Maehara, K., Horikoshi, N., Sato, K., Sato, Y., Shiraishi, K., Sugino, N., Osakabe, A., Tachiwana, H., Kagawa, W., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 1 15 2016, : : Epigenetics and Chromatin. 9, 1, 51.

研究成果: Contribution to journalArticle

24 引用 (Scopus)

Histone H4 lysine 20 acetylation is associated with gene repression in human cells

Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H. & Isaka, Y., 4 11 2016, : : Scientific reports. 6, 24318.

研究成果: Contribution to journalArticle

17 引用 (Scopus)

Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I

Katahira, J., Okuzaki, D., Inoue, H., Yoneda, Y., Maehara, K. & Ohkawa, Y., 8 2013, : : Nucleic acids research. 41, 14, p. 7060-7072 13 p.

研究成果: Contribution to journalArticle

37 引用 (Scopus)

Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas

Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., 10 2016, : : PloS one. 11, 10, e0165473.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle

Harada, A., Maehara, K., Sato, Y., Konno, D., Tachibana, T., Kimura, H. & Ohkawa, Y., 1 30 2015, : : Nucleic acids research. 43, 2, p. 775-786 12 p.

研究成果: Contribution to journalArticle

24 引用 (Scopus)

Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA

Osakabe, A., Adachi, F., Arimura, Y., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 10 7 2015, : : Open Biology. 5, 10, 150128.

研究成果: Contribution to journalArticle

12 引用 (Scopus)

Regulation of RNA polymerase II activation by histone acetylation in single living cells

Stasevich, T. J., Hayashi-Takanaka, Y., Sato, Y., Maehara, K., Ohkawa, Y., Sakata-Sogawa, K., Tokunaga, M., Nagase, T., Nozaki, N., McNally, J. G. & Kimura, H., 12 11 2014, : : Nature. 516, 7530, p. 272-275 4 p.

研究成果: Contribution to journalArticle

120 引用 (Scopus)

Sensitive detection of fluorescence in western blotting by merging images

Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 2018, : : PloS one. 13, 1, e0191532.

研究成果: Contribution to journalArticle

7 引用 (Scopus)

SraTailor: Graphical user interface software for processing and visualizing ChIP-seq data

Oki, S., Maehara, K., Ohkawa, Y. & Meno, C., 12 1 2014, : : Genes to Cells. 19, 12, p. 919-926 8 p.

研究成果: Contribution to journalArticle

14 引用 (Scopus)

Structure and function of human histone H3.Y nucleosome

Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 7 27 2016, : : Nucleic acids research. 44, 13, p. 6127-6141 15 p.

研究成果: Contribution to journalArticle

19 引用 (Scopus)

Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

Fukuda, S., Kaneshige, A., Kaji, T., Noguchi, Y. T., Takemoto, Y., Zhang, L., Tsujikawa, K., Kokubo, H., Uezumi, A., Maehara, K., Harada, A., Ohkawa, Y. & Fukada, S. I., 9 2019, : : eLife. 8, e48284.

研究成果: Contribution to journalArticle

公開
6 引用 (Scopus)

Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis

Ueda, J., Harada, A., Urahama, T., Machida, S., Maehara, K., Hada, M., Makino, Y., Nogami, J., Horikoshi, N., Osakabe, A., Taguchi, H., Tanaka, H., Tachiwana, H., Yao, T., Yamada, M., Iwamoto, T., Isotani, A., Ikawa, M., Tachibana, T., Okada, Y. および4人, Kimura, H., Ohkawa, Y., Kurumizaka, H. & Yamagata, K., 1 17 2017, : : Cell Reports. 18, 3, p. 593-600 8 p.

研究成果: Contribution to journalArticle

30 引用 (Scopus)

The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach

Odawara, J., Harada, A., Yoshimi, T., Maehara, K., Tachibana, T., Okada, S., Akashi, K. & Ohkawa, Y., 10 20 2011, : : BMC genomics. 12, 516.

研究成果: Contribution to journalArticle

26 引用 (Scopus)

The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis

Abdalla, M. O. A., Yamamoto, T., Maehara, K., Nogami, J., Ohkawa, Y., Miura, H., Poonperm, R., Hiratani, I., Nakayama, H., Nakao, M. & Saitoh, N., 12 1 2019, : : Nature communications. 10, 1, 3778.

研究成果: Contribution to journalArticle

公開
6 引用 (Scopus)

The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation

Kudou, K., Komatsu, T., Nogami, J., Maehara, K., Harada, A., Saeki, H., Oki, E., Maehara, Y. & Ohkawa, Y., 2017, : : Open Biology. 7, 9, 170119.

研究成果: Contribution to journalArticle

14 引用 (Scopus)

Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms

Nakamura, T., Murakami, K., Tada, H., Uehara, Y., Nogami, J., Maehara, K., Ohkawa, Y., Saitoh, H., Nishitani, H., Ono, T., Nishi, R., Yokoi, M., Sakai, W. & Sugasawa, K., 4 1 2017, : : Genes to Cells. 22, 4, p. 392-405 14 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Tissue-specific expression of histone H3 variants diversified after species separation

Maehara, K., Harada, A., Sato, Y., Matsumoto, M., Nakayama, K. I., Kimura, H. & Ohkawa, Y., 9 17 2015, : : Epigenetics and Chromatin. 8, 1, 35.

研究成果: Contribution to journalArticle

21 引用 (Scopus)