年単位の研究成果
研究成果 1989 2019
- 100 - 150 / 379 件中
- 出版年、タイトル (降順)
Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts
Cremasco, V., Decker, C. E., Stumpo, D., Blackshear, P. J., Nakayama, K., Nakayama, K., Lupu, T. S., Graham, D. B., Novack, D. V. & Faccio, R., 12 1 2012, : : Journal of Bone and Mineral Research. 27, 12, p. 2452-2463 12 p.研究成果: ジャーナルへの寄稿 › 記事
Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin
Oshikawa, K., Matsumoto, M., Oyamada, K. & Nakayama, K., 2 3 2012, : : Journal of Proteome Research. 11, 2, p. 796-807 12 p.研究成果: ジャーナルへの寄稿 › 記事
Regulation of APC/C Cdc20 activity by RASSF1A-APC/C Cdc20 circuitry
Chow, C., Wong, N., Pagano, M., Lun, S. W. M., Nakayama, K. I., Nakayama, K. & Lo, K. W., 4 12 2012, : : Oncogene. 31, 15, p. 1975-1987 13 p.研究成果: ジャーナルへの寄稿 › 記事
Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ
Shin, E. J., Duong, C. X., Nguyen, X. K. T., Li, Z., Bing, G., Bach, J. H., Park, D. H., Nakayama, K., Ali, S. F., Kanthasamy, A. G., Cadet, J. L., Nabeshima, T. & Kim, H. C., 6 15 2012, : : Behavioural Brain Research. 232, 1, p. 98-113 16 p.研究成果: ジャーナルへの寄稿 › 記事
SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction
Fukushima, H., Matsumoto, A., Inuzuka, H., Zhai, B., Lau, A. W., Wan, L., Gao, D., Shaik, S., Yuan, M., Gygi, S. P., Jimi, E., Asara, J. M., Nakayama, K., Nakayama, K. I. & Wei, W., 5 31 2012, : : Cell Reports. 1, 5, p. 434-443 10 p.研究成果: ジャーナルへの寄稿 › 記事
The amelioration of renal damage in Skp2-deficient mice canceled by p27Kip1 deficiency in Skp2-/- p27-/- mice
Suzuki, S., Fukasawa, H., Misaki, T., Togawa, A., Ohashi, N., Kitagawa, K., Kotake, Y., Liu, N., Niida, H., Nakayama, K., Nakayama, K. I., Yamamoto, T. & Kitagawa, M., 4 27 2012, : : PloS one. 7, 4, e36249.研究成果: ジャーナルへの寄稿 › 記事
The pathophysiologic role of the protein kinase Cδ pathway in the intervertebral discs of rabbits and mice: In vitro, ex vivo, and in vivo studies
Ellman, M. B., Kim, J. S., An, H. S., Kroin, J. S., Li, X., Chen, D., Yan, D., Buechter, D. D., Nakayama, K., Liu, B., Morgan, S. & Im, H. J., 6 1 2012, : : Arthritis and rheumatism. 64, 6, p. 1950-1959 10 p.研究成果: ジャーナルへの寄稿 › 記事
The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis
Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 5 25 2012, : : Cell. 149, 5, p. 1098-1111 14 p.研究成果: ジャーナルへの寄稿 › 記事
Deficiency of Rap1-Binding Protein RAPL Causes Lymphoproliferative Disorders through Mislocalization of p27kip1
Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K. & Kinashi, T., 1 28 2011, : : Immunity. 34, 1, p. 24-38 15 p.研究成果: ジャーナルへの寄稿 › 記事
Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism
Fuster, J. J., González-Navarro, H., Vinué, A., Molina-Sànchez, P., Andrés-Manzano, M. J., Nakayama, K. I., Nakayama, K., Díez-Juan, A., Bernad, A., Rodríguez, C., Martínez-González, J. & Andrés, V., 11 1 2011, : : Arteriosclerosis, thrombosis, and vascular biology. 31, 11, p. 2455-2463 9 p.研究成果: ジャーナルへの寄稿 › 記事
Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice
Matsumoto, A., Susaki, E., Onoyama, I., Nakayama, K., Hoshino, M. & Nakayama, K., 10 1 2011, : : Molecular and Cellular Biology. 31, 20, p. 4176-4192 17 p.研究成果: ジャーナルへの寄稿 › 記事
Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression
Iriuchishima, H., Takubo, K., Matsuoka, S., Onoyama, I., Nakayama, K. I., Nojima, Y. & Suda, T., 2 24 2011, : : Blood. 117, 8, p. 2373-2377 5 p.研究成果: ジャーナルへの寄稿 › 記事
Fbxw7-dependent degradation of notch is required for control of "Stemness" and neuronal-glial differentiation in neural stem cells
Matsumoto, A., Onoyama, I., Sunabori, T., Kageyama, R., Okano, H. & Nakayama, K. I., 4 15 2011, : : Journal of Biological Chemistry. 286, 15, p. 13754-13764 11 p.研究成果: ジャーナルへの寄稿 › 記事
Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver
Onoyama, I., Suzuki, A., Matsumoto, A., Tomita, K., Katagiri, H., Oike, Y., Nakayama, K. & Nakayama, K., 1 4 2011, : : Journal of Clinical Investigation. 121, 1, p. 342-354 13 p.研究成果: ジャーナルへの寄稿 › 記事
Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress
Matsumoto, A., Tateishi, Y., Onoyama, I., Okita, Y., Nakayama, K. & Nakayama, K., 4 1 2011, : : Cancer Science. 102, 4, p. 749-755 7 p.研究成果: ジャーナルへの寄稿 › 記事
Four mood stabilizers commonly induce FEZ1 expression in human astrocytes
Yu, Z., Ono, C., Kim, H. B., Komatsu, H., Tanabe, Y., Sakae, N., Nakayama, K., Matsuoka, H., Sora, I., Bunney, W. E. & Tomita, H., 8 1 2011, : : Bipolar Disorders. 13, 5-6, p. 486-499 14 p.研究成果: ジャーナルへの寄稿 › 記事
Functional analyses of the activation loop of phototropin2 in Arabidopsis
Inoue, S. I., Matsushita, T., Tomokiyo, Y., Matsumoto, M., Nakayama, K., Kinoshita, T. & Shimazaki, K. I., 5 1 2011, : : Plant physiology. 156, 1, p. 117-128 12 p.研究成果: ジャーナルへの寄稿 › 記事
Impaired ovarian development and reduced fertility in female mice deficient in Skp2
Fotovati, A., Abu-Ali, S., Nakayama, K. & Nakayama, K., 6 1 2011, : : Journal of Anatomy. 218, 6, p. 668-677 10 p.研究成果: ジャーナルへの寄稿 › 記事
miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27 kip1, KPC1, and SOCS-1
Lu, C., Huang, X., Zhang, X., Roensch, K., Cao, Q., Nakayama, K., Blazar, B. R., Zeng, Y. & Zhou, X., 4 21 2011, : : Blood. 117, 16, p. 4293-4303 11 p.研究成果: ジャーナルへの寄稿 › 記事
P57 Is required for quiescence and maintenance of adult hematopoietic stem cells
Matsumoto, A., Takeishi, S., Kanie, T., Susaki, E., Onoyama, I., Tateishi, Y., Nakayama, K. & Nakayama, K., 9 2 2011, : : Cell stem cell. 9, 3, p. 262-271 10 p.研究成果: ジャーナルへの寄稿 › 記事
P57 Kip2 and p27 Kip1 cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
Zou, P., Yoshihara, H., Hosokawa, K., Tai, I., Shinmyozu, K., Tsukahara, F., Maru, Y., Nakayama, K., Nakayama, K. & Suda, T., 9 2 2011, : : Cell stem cell. 9, 3, p. 247-261 15 p.研究成果: ジャーナルへの寄稿 › 記事
PKCδ inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment
Shin, E. J., Duong, C. X., Nguyen, X. K. T., Bing, G., Bach, J. H., Park, D. H., Nakayama, K., Ali, S. F., Kanthasamy, A. G., Cadet, J. L., Nabeshima, T. & Kim, H. C., 8 1 2011, : : Neurochemistry International. 59, 1, p. 39-50 12 p.研究成果: ジャーナルへの寄稿 › 記事
Plasma gelsolin facilitates interaction between β2 glycoprotein I and α5β1 integrin
Bohgaki, M., Matsumoto, M., Atsumi, T., Kondo, T., Yasuda, S., Horita, T., Nakayama, K. I., Okumura, F., Hatakeyama, S. & Koike, T., 1 1 2011, : : Journal of Cellular and Molecular Medicine. 15, 1, p. 141-151 11 p.研究成果: ジャーナルへの寄稿 › 記事
Proteome of ubiquitin/MVB pathway: Possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation
Tachiyama, R., Ishikawa, D., Matsumoto, M., Nakayama, K. I., Yoshimori, T., Yokota, S., Himeno, M., Tanaka, Y. & Fujita, H., 4 1 2011, : : Genes to Cells. 16, 4, p. 448-466 19 p.研究成果: ジャーナルへの寄稿 › 記事
Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation
Matsuzaki, F., Shirane, M., Matsumoto, M. & Nakayama, K. I., 12 1 2011, : : Molecular biology of the cell. 22, 23, p. 4602-4620 19 p.研究成果: ジャーナルへの寄稿 › 記事
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Inuzuka, H., Shaik, S., Onoyama, I., Gao, D., Tseng, A., Maser, R. S., Zhai, B., Wan, L., Gutierrez, A., Lau, A. W., Xiao, Y., Christie, A. L., Aster, J., Settleman, J., Gygi, S. P., Kung, A. L., Look, T., Nakayama, K. I., Depinho, R. A. & Wei, W., 3 3 2011, : : Nature. 471, 7336, p. 104-109 6 p.研究成果: ジャーナルへの寄稿 › 記事
Skp2 is necessary for Myc-induced keratinocyte proliferation but dispensable for Myc oncogenic activity in the oral epithelium
Sistrunk, C., MacIas, E., Nakayama, K., Kim, Y. & Rodriguez-Puebla, M. L., 1 1 2011, : : American Journal of Pathology. 178, 6, p. 2470-2477 8 p.研究成果: ジャーナルへの寄稿 › 記事
The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo
Moroishi, T., Nishiyama, M., Takeda, Y., Iwai, K. & Nakayama, K. I., 9 7 2011, : : Cell metabolism. 14, 3, p. 339-351 13 p.研究成果: ジャーナルへの寄稿 › 記事
The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs
Rodriguez, S., Wang, L., Mumaw, C., Srour, E. F., Lo Celso, C., Nakayama, K. I. & Carlesso, N., 6 16 2011, : : Blood. 117, 24, p. 6509-6519 11 p.研究成果: ジャーナルへの寄稿 › 記事
TRIM8 regulates Nanog via Hsp90β-mediated nuclear translocation of STAT3 in embryonic stem cells
Okumura, F., Okumura, A. J., Matsumoto, M., Nakayama, K. & Hatakeyama, S., 10 1 2011, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1813, 10, p. 1784-1792 9 p.研究成果: ジャーナルへの寄稿 › 記事
UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53
Wu, H., Pomeroy, S. L., Ferreira, M., Teider, N., Mariani, J., Nakayama, K. I., Hatakeyama, S., Tron, V. A., Saltibus, L. F., Spyracopoulos, L. & Leng, R. P., 3 1 2011, : : Nature medicine. 17, 3, p. 347-355 9 p.研究成果: ジャーナルへの寄稿 › 記事
Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: Role of protein phosphatases
Ma, H., Yu, L., Byra, E. A., Hu, N., Kitagawa, K., Nakayama, K., Kawamoto, T. & Ren, J., 8 1 2010, : : Journal of Molecular and Cellular Cardiology. 49, 2, p. 322-329 8 p.研究成果: ジャーナルへの寄稿 › 記事
An animal model manifesting neurodegeneration and obesity
Susaki, E. & Nakayama, K. I., 7 2010, : : Aging. 2, 7, p. 453-456 4 p.研究成果: ジャーナルへの寄稿 › 記事
Comparative analysis of human Src-family kinase substrate specificity in vitro
Takeda, H., Kawamura, Y., Miura, A., Mori, M., Wakamatsu, A., Yamamoto, J. I., Isogai, T., Matsumoto, M., Nakayama, K., Natsume, T., Nomura, N. & Goshima, N., 11 5 2010, : : Journal of Proteome Research. 9, 11, p. 5982-5993 12 p.研究成果: ジャーナルへの寄稿 › 記事
Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts
Masuda, K., Ishikawa, Y., Onoyama, I., Unno, M., De Alborán, I. M., Nakayama, K. I. & Nakayama, K., 3 1 2010, : : Oncogene. 29, 12, p. 1798-1809 12 p.研究成果: ジャーナルへの寄稿 › 記事
Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis
Chan, C. H., Lee, S. W., Li, C. F., Wang, J., Yang, W. L., Wu, C. Y., Wu, J., Nakayama, K., Kang, H. Y., Huang, H. Y., Hung, M. C., Pandolfi, P. P. & Lin, H. K., 5 1 2010, : : Nature Cell Biology. 12, 5, p. 457-467 11 p.研究成果: ジャーナルへの寄稿 › 記事
Fbxo45, a novel ubiquitin ligase, regulates synaptic activity
Tada, H., Okano, H. J., Takagi, H., Shibata, S., Yao, I., Matsumoto, M., Saiga, T., Nakayama, K., Kashima, H., Takahashi, T., Setou, M. & Okano, H., 2 5 2010, : : Journal of Biological Chemistry. 285, 6, p. 3840-3849 10 p.研究成果: ジャーナルへの寄稿 › 記事
GABAA receptor subunit alteration-dependent diazepam insensitivity in the cerebellum of phospholipase C-related inactive protein knockout mice
Mizokami, A., Tanaka, H., Ishibashi, H., Umebayashi, H., Fukami, K., Takenawa, T., Nakayama, K., Yokoyama, T., Nabekura, J., Kanematsu, T. & Hirata, M., 7 1 2010, : : Journal of Neurochemistry. 114, 1, p. 302-310 9 p.研究成果: ジャーナルへの寄稿 › 記事
Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress
Hayakawa, H., Fujikane, A., Ito, R., Matsumoto, M., Nakayama, K. & Sekiguchi, M., 12 10 2010, : : Biochemical and Biophysical Research Communications. 403, 2, p. 220-224 5 p.研究成果: ジャーナルへの寄稿 › 記事
Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity
Susaki, E., Kaneko-Oshikawa, C., Miyata, K., Tabata, M., Yamada, T., Oike, Y., Katagiri, H. & Nakayama, K., 5 14 2010, : : Journal of Biological Chemistry. 285, 20, p. 15538-15547 10 p.研究成果: ジャーナルへの寄稿 › 記事
In vitro histone demethylase assay
Tsukada, Y. I. & Nakayama, K. I., 10 1 2010, : : Cold Spring Harbor Protocols. 5, 10研究成果: ジャーナルへの寄稿 › 記事
KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development
Tsukada, Y., Ishitani, T. & Nakayama, K., 3 1 2010, : : Genes and Development. 24, 5, p. 432-437 6 p.研究成果: ジャーナルへの寄稿 › 記事
Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: Clinical significance
Iwatsuki, M., Mimori, K., Lshii, H., Yokobori, T., Takatsuno, Y., Sato, T., Toh, H., Onoyama, I., Nakayama, K. I., Baba, H. & Mori, M., 4 15 2010, : : International Journal of Cancer. 126, 8, p. 1828-1837 10 p.研究成果: ジャーナルへの寄稿 › 記事
Loss of protein kinase C delta alters mammary gland development and apoptosis
Allen-Petersen, B. L., Miller, M. R., Neville, M. C., Anderson, S. M., Nakayama, K. & Reyland, M. E., 1 1 2010, : : Cell Death and Disease. 1, 1, e17.研究成果: ジャーナルへの寄稿 › 記事
Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4
Benirschke, R. C., Thompson, J. R., Nominé, Y., Wasielewski, E., Juranić, N., Macura, S., Hatakeyama, S., Nakayama, K. I., Botuyan, M. V. & Mer, G., 8 1 2010, : : Structure. 18, 8, p. 955-965 11 p.研究成果: ジャーナルへの寄稿 › 記事
Nedd4-interacting protein 2, a short half-life membrane protein degraded in lysosomes, negatively controls down-regulation of connexin43
Ohzono, C., Etoh, S., Matsumoto, M., Nakayama, K. I., Hirota, Y., Tanaka, Y. & Fujita, H., 6 17 2010, : : Biological and Pharmaceutical Bulletin. 33, 6, p. 951-957 7 p.研究成果: ジャーナルへの寄稿 › 記事
p27 modulates tropism of mesenchymal stem cells toward brain tumors
Gao, Y., Gu, C., Li, S., Tokuyama, T., Yokota, N., Nakayama, K. I., Kitagawa, M. & Namba, H., 7 1 2010, : : Experimental and Therapeutic Medicine. 1, 4, p. 695-699 5 p.研究成果: ジャーナルへの寄稿 › 記事
Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of γ-aminobutyric acid type A receptors
Fujii, M., Kanematsu, T., Ishibashi, H., Fukami, K., Takenawa, T., Nakayama, K., Moss, S. J., Nabekura, J. & Hirata, M., 2 12 2010, : : Journal of Biological Chemistry. 285, 7, p. 4837-4846 10 p.研究成果: ジャーナルへの寄稿 › 記事
Phosphorylation of the chromodomain changes the binding specificity of Cbx2 for methylated histone H3
Hatano, A., Matsumoto, M., Higashinakagawa, T. & Nakayama, K. I., 6 18 2010, : : Biochemical and Biophysical Research Communications. 397, 1, p. 93-99 7 p.研究成果: ジャーナルへの寄稿 › 記事
Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis
Old, J. B., Kratzat, S., Hoellein, A., Graf, S., Nilsson, J. A., Nilsson, L., Nakayama, K. I., Peschel, C., Cleveland, J. L. & Keller, U. B., 3 1 2010, : : Molecular Cancer Research. 8, 3, p. 353-362 10 p.研究成果: ジャーナルへの寄稿 › 記事