Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1989 2019

フィルター
記事
2005
34 引用 (Scopus)

p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2

Rodier, G., Makris, C., Coulombe, P., Scime, A., Nakayama, K., Nakayama, K. & Meloche, S., 1 3 2005, : : Journal of Cell Biology. 168, 1, p. 55-66 12 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
S Phase
Fibroblasts
Proteolysis
Half-Life
7 引用 (Scopus)

Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.

Kase, S., Yoshida, K., Nakayama, K., Nakayama, K., Ikeda, H., Harada, T., Harada, C., Ohgami, K., Shiratori, K. & Ohno, S., 1 1 2005, : : International journal of molecular medicine. 16, 2, p. 257-262 6 p.

研究成果: ジャーナルへの寄稿記事

Retinoblastoma
Retina
Phosphorylation
Bromodeoxyuridine
Proliferating Cell Nuclear Antigen
268 引用 (Scopus)

Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase stabilizes β-catenin through inhibition of its ubiquitination

Hino, S. I., Tanji, C., Nakayama, K. & Kikuchi, A., 10 1 2005, : : Molecular and cellular biology. 25, 20, p. 9063-9072 10 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Ubiquitination
Cyclic AMP-Dependent Protein Kinases
Phosphorylation
TCF Transcription Factors
25 引用 (Scopus)

Role of PRIP-1, a novel Ins(1,4,5)P3 binding protein, in Ins(1,4,5)P3-mediated Ca2+ signaling

Harada, K., Takeuchi, H., Oike, M., Matsuda, M., Kanematsu, T., Yagisawa, H., Nakayama, K. I. I., Maeda, K., Erneux, C. & Hirata, M., 2 1 2005, : : Journal of cellular physiology. 202, 2, p. 422-433 12 p.

研究成果: ジャーナルへの寄稿記事

Carrier Proteins
Inositol
Polyphosphates
Enzyme activity
Phosphoric Monoester Hydrolases
62 引用 (Scopus)

Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation

Kotake, Y., Nakayama, K., Ishida, N. & Nakayama, K., 1 14 2005, : : Journal of Biological Chemistry. 280, 2, p. 1095-1102 8 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Serine
Stabilization
Cell Cycle Resting Phase
Mutation
57 引用 (Scopus)

Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle

Hara, T., Kamura, T., Kotoshiba, S., Takahashi, H., Fujiwara, K., Onoyama, I., Shirakawa, M., Mizushima, N. & Nakayama, K., 11 1 2005, : : Molecular and cellular biology. 25, 21, p. 9292-9303 12 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
G1 Phase
Ubiquitin
Cell Cycle
Proteins
47 引用 (Scopus)

Suppression of cell migration by protein kinase Cδ

Jackson, D., Zheng, Y., Lyo, D., Shen, Y., Nakayama, K., Nakayama, K. I., Humphries, M. J., Reyland, M. E. & Foster, D. A., 4 21 2005, : : Oncogene. 24, 18, p. 3067-3072 6 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Cell Movement
Fibroblasts
MCF-7 Cells
Eels
41 引用 (Scopus)

Targeted destruction of c-Myc by an engineered ubiquitin ligase suppresses cell transformation and tumor formation

Hatakeyama, S., Watanabe, M., Fujii, Y. & Nakayama, K. I., 9 1 2005, : : Cancer Research. 65, 17, p. 7874-7879 6 p.

研究成果: ジャーナルへの寄稿記事

Ligases
Ubiquitin
Oncogene Proteins
Neoplasms
NIH 3T3 Cells
25 引用 (Scopus)

Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase

Yogosawa, S., Hatakeyama, S., Nakayama, K., Miyoshi, H., Kohsaka, S. & Akazawa, C., 12 16 2005, : : Journal of Biological Chemistry. 280, 50, p. 41619-41627 9 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Ligases
Ubiquitin
Sorting
Degradation
85 引用 (Scopus)

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle

Jiang, H., Chang, F. C., Ross, A. E., Lee, J., Nakayama, K., Nakayama, K. & Desiderio, S., 6 10 2005, : : Molecular Cell. 18, 6, p. 699-709 11 p.

研究成果: ジャーナルへの寄稿記事

VDJ Recombinases
Ubiquitination
Cell Cycle
S Phase
SKP Cullin F-Box Protein Ligases
2004
238 引用 (Scopus)

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

Furuyama, T., Kitayama, K., Shimoda, Y., Ogawa, M., Sone, K., Yoshida-Araki, K., Hisatsune, H., Nishikawa, S. I., Nakayama, K., Nakayama, K., Ikeda, K., Motoyama, N. & Mori, N., 8 13 2004, : : Journal of Biological Chemistry. 279, 33, p. 34741-34749 9 p.

研究成果: ジャーナルへの寄稿記事

Endothelial cells
Endothelial Cells
Vascular Endothelial Growth Factor A
Embryonic Stem Cells
Stem cells
120 引用 (Scopus)

AIRE Functions as an E3 Ubiquitin Ligase

Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 1 19 2004, : : Journal of Experimental Medicine. 199, 2, p. 167-172 6 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Self Tolerance
Autoimmune Polyendocrinopathies
Missense Mutation
Proteasome Endopeptidase Complex
174 引用 (Scopus)

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

Takao, O., Ryu, H., Minamishima, Y. A., Macip, S., Sagara, J., Nakayama, K., Aaronson, S. A. & Lee, S. W., 2 1 2004, : : Nature Cell Biology. 6, 2, p. 121-128 8 p.

研究成果: ジャーナルへの寄稿記事

Apoptosis
Proteins
Mitochondria
Caspase 2
Caspase 9
135 引用 (Scopus)

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70

Urushitani, M., Kurisu, J., Tateno, M., Hatakeyama, S., Nakayama, K., Kato, S. & Takahashi, R., 7 1 2004, : : Journal of Neurochemistry. 90, 1, p. 231-244 14 p.

研究成果: ジャーナルへの寄稿記事

HSC70 Heat-Shock Proteins
Heat-Shock Proteins
Superoxide Dismutase
Degradation
Proteins
93 引用 (Scopus)

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT

Mirza, A. M., Gysin, S., Malek, N., Nakayama, K. I., Roberts, J. M. & McMahon, M., 12 1 2004, : : Molecular and cellular biology. 24, 24, p. 10868-10881 14 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle Proteins
Protein Kinases
Phosphatidylinositol 3-Kinase
S Phase
Cell Cycle
318 引用 (Scopus)

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase

Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K. & Nakayama, K., 12 1 2004, : : Nature Cell Biology. 6, 12, p. 1229-1235 7 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
G1 Phase
Ligases
Ubiquitin
Proteolysis
88 引用 (Scopus)

Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C δ

Li, B., Wang, X., Rasheed, N., Hu, Y., Boast, S., Ishii, T., Nakayama, K., Nakayama, K. I. & Golf, S. P., 8 1 2004, : : Genes and Development. 18, 15, p. 1824-1837 14 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Oxidative Stress
Osteoblasts
Peroxiredoxins
DNA Damage
16 引用 (Scopus)

Distribution of p27(KIP1), cylin D1, and proliferating cell nuclear antigen after retinal detachment

Yoshida, K., Kase, S., Nakayama, K., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ohno, S. & Nakayama, K., 5 1 2004, : : Graefe's Archive for Clinical and Experimental Ophthalmology. 242, 5, p. 437-441 5 p.

研究成果: ジャーナルへの寄稿記事

Cyclin D1
Proliferating Cell Nuclear Antigen
Retinal Detachment
Retinal Pigment Epithelium
Retina
29 引用 (Scopus)

Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4: Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation

Tamamori-Adachi, M., Hayashida, K., Nobori, K., Omizu, C., Yamada, K., Sakamoto, N., Kamura, T., Fukuda, K., Ogawa, S., Nakayama, K. & Kitajima, S., 11 26 2004, : : Journal of Biological Chemistry. 279, 48, p. 50429-50436 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase 4
Cyclin D1
Cell proliferation
Cardiac Myocytes
Cyclin-Dependent Kinase 2
33 引用 (Scopus)

Early embryonic death in mice lacking the β-catenin-binding protein duplin

Nishiyama, M., Nakayama, K., Tsunematsu, R., Tsukiyama, T., Kikuchi, A. & Nakayama, K. I., 10 1 2004, : : Molecular and cellular biology. 24, 19, p. 8386-8394 9 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Carrier Proteins
Embryonic Structures
Primitive Streak
Wnt Signaling Pathway
266 引用 (Scopus)

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

Mao, J. H., Perez-Iosada, J., Wu, D., DelRosario, R., Tsunematsu, R., Nakayama, K. I., Brown, K., Bryson, S. & Balmain, A., 12 9 2004, : : Nature. 432, 7018, p. 775-779 5 p.

研究成果: ジャーナルへの寄稿記事

Tumor Suppressor Genes
Neoplasms
Carcinogenesis
Aurora Kinase A
Radiation
40 引用 (Scopus)

Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis

Okumura, F., Hatakeyama, S., Matsumoto, M., Kamura, T. & Nakayama, K., 12 17 2004, : : Journal of Biological Chemistry. 279, 51, p. 53533-53543 11 p.

研究成果: ジャーナルへの寄稿記事

Fasciculation
Ligases
Ubiquitin
Elongation
Proteins
85 引用 (Scopus)

GABAA receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein

Terunuma, M., Jang, I. S., Ha, S. H., Kittler, J. T., Kanematsu, T., Jovanovic, J. N., Nakayama, K. I., Akaike, N., Ryu, S. H., Moss, S. J. & Hirata, M., 8 11 2004, : : Journal of Neuroscience. 24, 32, p. 7074-7084 11 p.

研究成果: ジャーナルへの寄稿記事

Protein Phosphatase 1
Type C Phospholipases
GABA-A Receptors
Proteins
Phosphorylation
4 引用 (Scopus)

Hypersensitivity to pentylenetetrazol-induced convulsion in mice lacking the PLC-related inactive protein-1

Yamaguchi, T., Kubota, T., Kanematsu, T., Nakayama, K., Hirata, M. & Yamamoto, T., 10 29 2004, : : Brain Research. 1025, 1-2, p. 237-240 4 p.

研究成果: ジャーナルへの寄稿記事

Pentylenetetrazole
Type C Phospholipases
Hypersensitivity
Seizures
Proteins
70 引用 (Scopus)

Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones

Hatakeyama, S., Matsumoto, M., Yada, M. & Nakayama, K., 6 1 2004, : : Genes to Cells. 9, 6, p. 533-548 16 p.

研究成果: ジャーナルへの寄稿記事

Molecular Chaperones
Ubiquitin-Protein Ligases
Proteins
Two-Hybrid System Techniques
Proteolysis
15 引用 (Scopus)

Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body

Yoshida, K., Nakayama, K., Kase, S., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ohno, S., Nishi, S. & Nakayama, K. I., 5 1 2004, : : Anatomy and Embryology. 208, 2, p. 145-150 6 p.

研究成果: ジャーナルへの寄稿記事

Ciliary Body
Retinal Pigment Epithelium
Bromodeoxyuridine
Cyclin-Dependent Kinase Inhibitor p27
G1 Phase
23 引用 (Scopus)

Involvement of p27KIP1 in the proliferation of the developing corneal endothelium

Yoshida, K., Kase, S., Nakayama, K., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ilieva, I. B., Ohno, S., Nishi, S. & Nakayama, K. I., 7 1 2004, : : Investigative Ophthalmology and Visual Science. 45, 7, p. 2163-2167 5 p.

研究成果: ジャーナルへの寄稿記事

Corneal Endothelium
Proliferating Cell Nuclear Antigen
Cornea
Parturition
Bromodeoxyuridine
77 引用 (Scopus)

Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries.

Blaschke, F., Leppanen, O., Takata, Y., Caglayan, E., Liu, J., Fishbein, M. C., Kappert, K., Nakayama, K., Collins, A. R., Fleck, E., Hsueh, W. A., Law, R. E. & Bruemmer, D., 1 1 2004, : : Circulation research. 95, 12

研究成果: ジャーナルへの寄稿記事

Neointima
Vascular Smooth Muscle
Carotid Arteries
Smooth Muscle Myocytes
Cell Proliferation
111 引用 (Scopus)

Molecular clearance of ataxin-3 is regulated by a mammalian E4

Matsumoto, M., Yada, M., Hatakeyama, S., Ishimoto, H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M. & Nakayama, K. I., 2 11 2004, : : EMBO Journal. 23, 3, p. 659-669 11 p.

研究成果: ジャーナルへの寄稿記事

Machado-Joseph Disease
Degradation
Ubiquitin
Gene therapy
Ubiquitination
186 引用 (Scopus)

Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T. & Nakayama, K., 3 5 2004, : : Journal of Biological Chemistry. 279, 10, p. 9417-9423 7 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Endothelial cells
Blood Vessels
Embryonic Structures
Degradation
473 引用 (Scopus)

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K. & Nakayama, K. I., 5 19 2004, : : EMBO Journal. 23, 10, p. 2116-2125 10 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Phosphorylation
Degradation
Ubiquitination
Threonine
264 引用 (Scopus)

Skp2-Mediated degradation of p27 regulates progression into mitosis

Nakayama, K., Nagahama, H., Minamishima, Y. A., Miyake, S., Ishida, N., Hatakeyama, S., Kitagawa, M., Iemura, S. I., Natsume, T. & Nakayama, K. I., 5 1 2004, : : Developmental Cell. 6, 5, p. 661-672 12 p.

研究成果: ジャーナルへの寄稿記事

Mitosis
Degradation
G2 Phase
Proteolysis
Phenotype
88 引用 (Scopus)

Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9

Komatsu, T., Mizusaki, H., Mukai, T., Ogawa, H., Baba, D., Shirakawa, M., Hatakeyama, S., Nakayama, K. I., Yamamoto, H., Kikuchi, A. & Morohashi, K. I., 10 1 2004, : : Molecular Endocrinology. 18, 10, p. 2451-2462 12 p.

研究成果: ジャーナルへの寄稿記事

Steroidogenic Factor 1
Ubiquitin
Sumoylation
Protein Inhibitors of Activated STAT
STAT1 Transcription Factor
51 引用 (Scopus)

Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner

Akiyoshi, H., Hatakeyama, S., Pitkänen, J., Mouri, Y., Doucas, V., Kudoh, J., Tsurugaya, K., Uchida, D., Matsushima, A., Oshikawa, K., Nakayama, K., Shimizu, N., Peterson, P. & Matsumoto, M., 8 6 2004, : : Journal of Biological Chemistry. 279, 32, p. 33984-33991 8 p.

研究成果: ジャーナルへの寄稿記事

Proteasome Endopeptidase Complex
Cells
Nuclear Matrix
Cell Line
Cyclic AMP Response Element-Binding Protein
32 引用 (Scopus)

The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCF Skp2 ubiquitin ligase

Tokarz, S., Berset, C., La Rue, J., Friedman, K., Nakayama, K., Nakayama, K., Zhang, D. E. & Lanker, S., 11 5 2004, : : Journal of Biological Chemistry. 279, 45, p. 46424-46430 7 p.

研究成果: ジャーナルへの寄稿記事

SKP Cullin F-Box Protein Ligases
Proteolysis
Interferon Type I
Ubiquitination
Ligases
57 引用 (Scopus)

The Papillomavirus E7 Oncoprotein Is Ubiquitinated by UbcH7 and Cullin 1- and Skp2-Containing E3 Ligase

Oh, K. J., Kalinina, A., Wang, J., Nakayama, K., Nakayama, K. I. & Bagchi, S., 5 1 2004, : : Journal of virology. 78, 10, p. 5338-5346 9 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Papillomaviridae
Oncogene Proteins
Ubiquitin
ligases
63 引用 (Scopus)

The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals

Kamezaki, K., Shimoda, K., Numata, A., Matsuda, T., Nakayama, K. I. & Harada, M., 8 1 2004, : : International Immunology. 16, 8, p. 1173-1179 7 p.

研究成果: ジャーナルへの寄稿記事

Endotoxins
Injections
Shock
Interleukin-12
Serum
8 引用 (Scopus)

Tyk2 is essential for IFN-α-induced gene expression in mast cells

Mori, Y., Hirose, K., Suzuki, K., Nakajima, H., Seto, Y., Ikeda, K., Shimoda, K., Nakayama, K., Saito, Y. & Iwamoto, I., 2004, : : International Archives of Allergy and Immunology. 134, SUPPL. 1, p. 25-29 5 p.

研究成果: ジャーナルへの寄稿記事

Mast Cells
Monocyte Chemoattractant Proteins
Gene Expression
Bone Marrow
Bacterial Infections
88 引用 (Scopus)

U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy

Hatakeyama, S., Matsumoto, M., Kamura, T., Murayama, M., Chui, D. H., Planel, E., Takahashi, R., Nakayama, K. & Takashima, A., 10 1 2004, : : Journal of Neurochemistry. 91, 2, p. 299-307 9 p.

研究成果: ジャーナルへの寄稿記事

HSC70 Heat-Shock Proteins
Tauopathies
Ubiquitination
Neurofibrillary Tangles
Proteins
307 引用 (Scopus)

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R. C., Conaway, J. W. & Nakayama, K., 12 15 2004, : : Genes and Development. 18, 24, p. 3055-3065 11 p.

研究成果: ジャーナルへの寄稿記事

Suppressor of Cytokine Signaling Proteins
Ligases
Ubiquitin
Cullin Proteins
RNA Interference
2003
110 引用 (Scopus)

A novel route for connexin 43 to inhibit cell proliferation: Negative regulation of S-phase kinase-associated protein (Skp 2)

Zhang, Y. W., Nakayama, K., Nakayama, K. & Morita, I., 4 1 2003, : : Cancer Research. 63, 7, p. 1623-1630 8 p.

研究成果: ジャーナルへの寄稿記事

S-Phase Kinase-Associated Proteins
Connexin 43
Cell Proliferation
Embryonic Structures
Fibroblasts
65 引用 (Scopus)

Association of Cathepsin E Deficiency with Development of Atopic Dermatitis

Tsukuba, T., Okamoto, K., Okamoto, Y., Yanagawa, M., Kohmura, K., Yasuda, Y., Uchi, H., Nakahara, T., Furue, M., Nakayama, K., Kadowaki, T., Yamamoto, K. & Nakayama, K. I., 12 1 2003, : : Journal of biochemistry. 134, 6, p. 893-902 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin E
Atopic Dermatitis
Interleukin-18
Interleukin-1
T-cells
68 引用 (Scopus)

Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein

Imaki, H., Nakayama, K., Delehouzee, S., Handa, H., Kitagawa, M., Kamura, T. & Nakayama, K. I., 8 1 2003, : : Cancer Research. 63, 15, p. 4607-4613 7 p.

研究成果: ジャーナルへの寄稿記事

GA-Binding Protein Transcription Factor
Cell Cycle
Electrophoretic Mobility Shift Assay
S Phase
Genetic Promoter Regions
47 引用 (Scopus)

Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a

Kaneko, C., Hatakeyama, S., Matsumoto, M., Yada, M., Nakayama, K. & Nakayama, K., 1 10 2003, : : Biochemical and Biophysical Research Communications. 300, 2, p. 297-304 8 p.

研究成果: ジャーナルへの寄稿記事

Ligases
Ubiquitin
Genes
TATA Box
5' Flanking Region
218 引用 (Scopus)

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation

Kamura, T., Hara, T., Kotoshiba, S., Yada, M., Ishida, N., Imaki, H., Hatakeyama, S., Nakayama, K. & Nakayama, K. I., 9 2 2003, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 18, p. 10231-10236 6 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Cyclin-Dependent Kinase Inhibitor p57
Cell Cycle
Cyclin E
Ubiquitin-Protein Ligases
49 引用 (Scopus)

Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice

Seto, Y., Nakajima, H., Suto, A., Shimoda, K., Saito, Y., Nakayama, K. & Iwamoto, I., 1 15 2003, : : Journal of Immunology. 170, 2, p. 1077-1083 7 p.

研究成果: ジャーナルへの寄稿記事

Th2 Cells
Inflammation
Interleukin-13
Interleukin-12
Eosinophils
83 引用 (Scopus)

Estrogens Down-regulate p27Kip1 in Breast Cancer Cells through Skp2 and through Nuclear Export Mediated by the ERK Pathway

Foster, J. S., Fernando, R. I., Ishida, N., Nakayama, K. I. & Wimalasena, J., 10 17 2003, : : Journal of Biological Chemistry. 278, 42, p. 41355-41366 12 p.

研究成果: ジャーナルへの寄稿記事

Cell Nucleus Active Transport
Extracellular Signal-Regulated MAP Kinases
MCF-7 Cells
Estrogens
Estrogen Receptor Modulators
78 引用 (Scopus)

Impaired degradation of inhibitory subunit of NF-κB (IκB) and β-catenin as a result of targeted disruption of the β-TrCP1 gene

Nakayama, K., Hatakeyama, S., Maruyama, S. I., Kikuchi, A., Onoé, K., Good, R. A. & Nakayama, K. I., 7 22 2003, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 15, p. 8752-8757 6 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Genes
F-Box Proteins
Wnt Signaling Pathway
Polyploidy
22 引用 (Scopus)

Intracellular signal transduction of interferon on the suppression of haematopoietic progenitor cell growth

Kato, K., Kamezaki, K., Shimoda, K., Numata, A., Haro, T., Aoki, K., Ishikawa, F., Takase, K., ariyama, H., Matsuda, T., Miyamoto, T., Nagafuji, K., Gondo, H., Nakayama, K. & Harada, M., 11 1 2003, : : British Journal of Haematology. 123, 3, p. 528-535 8 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Interferons
Signal Transduction
TYK2 Kinase
Growth
13 引用 (Scopus)

Limitin, an interferon-like cytokine, transduces inhibitory signals on B-cell growth through activation of Tyk2, but not Stat1, followed by induction and nuclear translocation of Daxx

Aoki, K., Shimoda, K., Oritani, K., Matsuda, T., Kamezaki, K., Muromoto, R., Numata, A., Tamiya, S., Haro, T., Ishikawa, F., Takase, K., Yamamoto, T., Yumioka, T., Miyamoto, T., Nagafuji, K., Gondo, H., Nagafuchi, S., Nakayama, K. & Harada, M., 1 1 2003, : : Experimental Hematology. 31, 12, p. 1317-1322 6 p.

研究成果: ジャーナルへの寄稿記事

Interferons
B-Lymphocytes
Cytokines
Growth
Interferon Regulatory Factor-1