• 2807 引用
  • 30 h指数
1991 …2020

Research output per year

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

2011

Simultaneous two-dimensional HPLC determination of free d-serine and d-alanine in the brain and periphery of mutant rats lacking d-amino-acid oxidase

Miyoshi, Y., Hamase, K., Okamura, T., Konno, R., Kasai, N., Tojo, Y. & Zaitsu, K., 11 1 2011, : : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 29, p. 3184-3189 6 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)
2010

6,7-Difluoro-1,4-dihydro-1-methyl-4-oxo-3-quinolinecarboxylic acid, a newly designed fluorescence enhancement-type derivatizing reagent for amino compounds

Hirano, J., Hamase, K., Miyata, H. & Zaitsu, K., 3 1 2010, : : Journal of Fluorescence. 20, 2, p. 615-624 10 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Brain-specific Phgdh deletion reveals a pivotal role for l-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain

Yang, J. H., Wada, A., Yoshida, K., Miyoshi, Y., Sayano, T., Esaki, K., Kinoshita, M. O., Tomonaga, S., Azuma, N., Watanabe, M., Hamase, K., Zaitsu, K., MacHida, T., Messing, A., Itohara, S., Hirabayashi, Y. & Furuya, S., 12 31 2010, : : Journal of Biological Chemistry. 285, 53, p. 41380-41390 11 p.

研究成果: ジャーナルへの寄稿記事

70 引用 (Scopus)

Mutant mice and rats lacking D-amino acid oxidase

Konno, R., Hamase, K., Maruyama, R. & Zaitsu, K., 6 2010, : : Chemistry and Biodiversity. 7, 6, p. 1450-1458 9 p.

研究成果: ジャーナルへの寄稿評論記事

20 引用 (Scopus)

Sensitive and precise 2D-HPLC determination of D-amino acids in real biological samples

Hamase, K., 12 1 2010, : : Seikagaku. 82, 2, p. 150-154 5 p.

研究成果: ジャーナルへの寄稿記事

Simultaneous determination of hydrophilic amino acid enantiomers in mammalian tissues and physiological fluids applying a fully automated micro-two-dimensional high-performance liquid chromatographic concept

Hamase, K., Miyoshi, Y., Ueno, K., Han, H., Hirano, J., Morikawa, A., Mita, M., Kaneko, T., Lindner, W. & Zaitsu, K., 2 12 2010, : : Journal of Chromatography A. 1217, 7, p. 1056-1062 7 p.

研究成果: ジャーナルへの寄稿記事

63 引用 (Scopus)
2009

Analysis of small smounts of D-Amino acids and the study of their physiological functions in mammals

Hamase, K., Morikawa, A., Etoh, S., Tojo, Y., Miyoshi, Y. & Zaitsu, K., 8 2009, : : analytical sciences. 25, 8, p. 961-968 8 p.

研究成果: ジャーナルへの寄稿評論記事

47 引用 (Scopus)
79 引用 (Scopus)

Enantioselective visualization of D-alanine in rat anterior pituitary gland: Localization to ACTH-secreting cells

Etoh, S., Hamase, K., Morikawa, A., Ohgusu, T. & Zaitsu, K., 1 1 2009, : : Analytical and Bioanalytical Chemistry. 393, 1, p. 217-223 7 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis

Tojo, Y., Hamase, K., Konno, R., Satoru, K., Ohdo, S. & Zaitsu, K., 2 1 2009, : : Journal of Separation Science. 32, 3, p. 430-436 7 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)
2008

Automated and simultaneous two-dimensional micro-high-performance liquid chromatographic determination of proline and hydroxyproline enantiomers in mammals

Tojo, Y., Hamase, K., Nakata, M., Morikawa, A., Mita, M., Ashida, Y., Lindner, W. & Zaitsu, K., 11 1 2008, : : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 875, 1, p. 174-179 6 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)
18 引用 (Scopus)

Structural and photophysical properties of novel dual fluorescent compounds, 1-aryl-substituted 6-methoxy-4-quinolones

Hirano, J., Hamase, K., Akita, T. & Zaitsu, K., 10 1 2008, : : Luminescence. 23, 5, p. 350-355 6 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)
2007

A Genetic Variant of the Serine Racemase Gene Is Associated with Schizophrenia

Morita, Y., Ujike, H., Tanaka, Y., Otani, K., Kishimoto, M., Morio, A., Kotaka, T., Okahisa, Y., Matsushita, M., Morikawa, A., Hamase, K., Zaitsu, K. & Kuroda, S., 5 15 2007, : : Biological Psychiatry. 61, 10, p. 1200-1203 4 p.

研究成果: ジャーナルへの寄稿記事

77 引用 (Scopus)

Alterations in D-amino acid levels in the brains of mice and rats after the administration of D-amino acids

Morikawa, A., Hamase, K., Inoue, T., Konno, R. & Zaitsu, K., 1 1 2007, : : Amino Acids. 32, 1, p. 13-20 8 p.

研究成果: ジャーナルへの寄稿記事

29 引用 (Scopus)

A ratiometric fluorescent chemosensor, 1,10-phenanthroline-4,7-dione, for anions in aqueous-organic media

Hirano, J., Miyata, H., Hamase, K. & Zaitsu, K., 7 9 2007, : : Tetrahedron Letters. 48, 28, p. 4861-4864 4 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)
71 引用 (Scopus)

Determination of small amounts of D-amino acids in mammals using column-switching HPLC

Hamase, K. & Zaitsu, K., 12 1 2007, D-Amino Acids: A New Frontier in Amino Acid and Protein Research - Practical Methods and Protocols. Nova Science Publishers, Inc., p. 93-102 10 p.

研究成果: 著書/レポートタイプへの貢献

Immunohistochemical localization of d-alanine to β-cells in rat pancreas

Morikawa, A., Hamase, K., Ohgusu, T., Etoh, S., Tanaka, H., Koshiishi, I., Shoyama, Y. & Zaitsu, K., 4 20 2007, : : Biochemical and Biophysical Research Communications. 355, 4, p. 872-876 5 p.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)
25 引用 (Scopus)
2006
16 引用 (Scopus)

High-throughput determination of free d-aspartic acid in mammals by enzyme immunoassay using specific monoclonal antibody

Ohgusu, T., Hamase, K., Tanaka, H., Shoyama, Y. & Zaitsu, K., 10 1 2006, : : Analytical Biochemistry. 357, 1, p. 15-20 6 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Meet the Guest Editors

Daunert, S., Deo, S., Hamase, K. & Vogel, M., 10 1 2006, : : Analytical and Bioanalytical Chemistry. 386, 3, p. 403-404 2 p.

研究成果: ジャーナルへの寄稿編集

Presence and origin of large amounts of d-proline in the urine of mutant mice lacking d-amino acid oxidase activity

Hamase, K., Takagi, S., Morikawa, A., Konno, R., Niwa, A. & Zaitsu, K., 10 1 2006, : : Analytical and Bioanalytical Chemistry. 386, 3, p. 705-711 7 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

Sensitive high-performance liquid chromatographic assay for D-amino-acid oxidase activity in mammalian tissues using a fluorescent non-natural substrate, 5-fluoro-D-tryptophan

Hamase, K., Nagayasu, R., Morikawa, A., Konno, R. & Zaitsu, K., 2 17 2006, : : Journal of Chromatography A. 1106, 1-2, p. 159-164 6 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)
2005

Crystal structure of 6-methoxy-4-quinolone, C10H9NO2·2H2O

Hirano, J., Hamase, K., Akita, T. & Zaitsu, K., 1 1 2005, : : Analytical Sciences: X-ray Structure Analysis Online. 21, 3, p. x45-x46

研究成果: ジャーナルへの寄稿コメント/討論

3 引用 (Scopus)

Sensitive determination of D-amino acids in mammals and the effect of D-amino-acid oxidase activity on their amounts

Hamase, K., Konno, R., Morikawa, A. & Zaitsu, K., 9 1 2005, : : Biological and Pharmaceutical Bulletin. 28, 9, p. 1578-1584 7 p.

研究成果: ジャーナルへの寄稿評論記事

64 引用 (Scopus)
2004
31 引用 (Scopus)

Chronopharmacology of Melatonin in Mice to Maximize the Antitumor Effect and Minimize the Rhythm Disturbance Effect

Akagi, T., Ushinohama, K., Ikesue, S., Yukawa, E., Higuchi, S., Hamase, K., Zaitsu, K. & Ohdo, S., 1 1 2004, : : Journal of Pharmacology and Experimental Therapeutics. 308, 1, p. 378-384 7 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Crystal structure of N-[(6-methoxy-4-oxo-1,4-dihydroquinolin-3-yl) methyl]-2,2-dimethylpropanamide

Hirano, J., Hamase, K., Akita, T. & Zaitsu, K., 1 1 2004, : : Analytical Sciences: X-ray Structure Analysis Online. 20, 3, p. x115-x116

研究成果: ジャーナルへの寄稿コメント/討論

1 引用 (Scopus)
23 引用 (Scopus)

Development of selective methods for the determination of small amounts of D-amino acids in mammals

Hamase, K. & Zaitsu, K., 7 1 2004, : : bunseki kagaku. 53, 7, p. 677-690 14 p.

研究成果: ジャーナルへの寄稿記事

Novel stable fluorophore, 6-methoxy-4-quinolone, with strong fluorescence in wide pH range of aqueous media, and its application as a fluorescent labeling reagent

Hirano, J., Hamase, K., Fukuda, H., Tomita, T. & Zaitsu, K., 12 3 2004, : : Journal of Chromatography A. 1059, 1-2, p. 225-231 7 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)
2003

2-Amino-3-phenylpyrazine, a sensitive fluorescence prelabeling reagent for the chromatographic or electrophoretic determination of saccharides

Yamamoto, K., Hamase, K. & Zaitsu, K., 7 4 2003, : : Journal of Chromatography A. 1004, 1-2, p. 99-106 8 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Determination of D-alanine in the rat central nervous system and periphery using column-switching high-performance liquid chromatography

Morikawa, A., Hamase, K. & Zaitsu, K., 1 1 2003, : : Analytical Biochemistry. 312, 1, p. 66-72 7 p.

研究成果: ジャーナルへの寄稿記事

81 引用 (Scopus)

Determination of endogenous melatonin in the individual pineal glands of inbred mice using precolumn oxidation reversed-phase micro-high-performance liquid chromatography

Tomita, T., Hamase, K., Hayashi, H., Fukuda, H., Hirano, J. & Zaitsu, K., 5 15 2003, : : Analytical Biochemistry. 316, 2, p. 154-161 8 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)
2002

D-amino acids in mammals and their diagnostic value

Hamase, K., Morikawa, A. & Zaitsu, K., 12 5 2002, : : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 781, 1-2, p. 73-91 19 p.

研究成果: ジャーナルへの寄稿評論記事

160 引用 (Scopus)
2 引用 (Scopus)
2001

Determination of free D-aspartic acid, D-serine and D-alanine in the brain of mutant mice lacking D-amino-acid oxidase activity

Morikawa, A., Hamase, K., Inoue, T., Konno, R., Niwa, A. & Zaitsu, K., 6 5 2001, : : Journal of Chromatography B: Biomedical Sciences and Applications. 757, 1, p. 119-125 7 p.

研究成果: ジャーナルへの寄稿記事

119 引用 (Scopus)

Determination of free D-proline and D-leucine in the brains of mutant mice lacking D-amino acid oxidase activity

Hamase, K., Inoue, T., Morikawa, A., Konno, R. & Zaitsu, K., 12 15 2001, : : Analytical Biochemistry. 298, 2, p. 253-258 6 p.

研究成果: ジャーナルへの寄稿記事

66 引用 (Scopus)
2000
46 引用 (Scopus)
25 引用 (Scopus)

Non-acidic matrix for the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of acid-labile compounds

Ohba, Y., Koto, N., Hamase, K. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 6, p. 659-661 3 p.

研究成果: ジャーナルへの寄稿コメント/討論

5 引用 (Scopus)

Reversed-phase HPLC of monosaccharides in glycoproteins derivatized with aminopyrazine with fluorescence detection

Wu, W., Hamase, K., Kiguchi, M., Yamamoto, K. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 9, p. 919-922 4 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

Selective masking of amino groups during fluorescence derivatization in the presence of a molecular imprint polymer

Hamase, K., Iwashita, K. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 4, p. 417-419 3 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)
1999

Alteration in the D-amino acid content of the rat pineal gland under anesthesia

Hamase, K., Homma, H., Takigawa, Y. & Imai, K., 1 1 1999, : : Amino Acids. 17, 3, p. 277-283 7 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Enantio-selective derivatization of amino compounds in the presence of a molecular imprint polymer

Hamase, K., Iwashita, K. & Zaitsu, K., 1 1 1999, : : analytical sciences. 15, 5, p. 411-412 2 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Heme-undecapeptide labeling on insulin for the immunoassay of insulin with chemiluminescence detection

Zaitsu, K., Kimura, Y., Ohba, Y., Hamase, K., Motomura, Y., Itose, M. & Ishiyama, M., 9 1999, : : analytical sciences. 15, 9, p. 871-878 8 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Reversible fluorescence derivatization of amino groups using dansylaminomethylmaleic acid via its anhydride

Sakata, K., Hamase, K., Sasaki, S., Maeda, M. & Zaitsu, K., 1 1 1999, : : analytical sciences. 15, 11, p. 1095-1099 5 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)