• 512 引用
  • 10 h指数
20122020
Pureに変更を加えた場合、すぐここに表示されます。

研究成果 2012 2020

  • 512 引用
  • 10 h指数
  • 34 記事
2020

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., 1 1 2020, : : FEBS Open Bio. 10, 1, p. 147-157 11 p.

研究成果: ジャーナルへの寄稿記事

公開
Methylation
Chemotherapy
DNA Methylation
Viruses
Drug Resistance
2019

Atrial fibrillation observed in a patient with esophageal cancer treated with fluorouracil

Moriyama, S., Yokoyama, T., Irie, K., Ito, M., Tsuchihashi, K., Fukata, M., Kusaba, H., Maruyama, T. & Akashi, K., 11 2019, : : Journal of Cardiology Cases. 20, 5, p. 183-186 4 p.

研究成果: ジャーナルへの寄稿記事

公開
Esophageal Neoplasms
Fluorouracil
Atrial Fibrillation
Coronary Vessels
Nicorandil

Clinicopathological review of solitary fibrous tumors: dedifferentiation is a major cause of patient death

Yamada, Y., Kohashi, K., Kinoshita, I., Yamamoto, H., Iwasaki, T., Yoshimoto, M., Ishihara, S., Toda, Y., Itou, Y., Koga, Y., Hashisako, M., Nozaki, Y., Kiyozawa, D., Kitahara, D., Inoue, T., Mukai, M., Honda, Y., Toyokawa, G., Tsuchihashi, K., Matsushita, Y. および9人, Fushimi, F., Taguchi, K., Tamiya, S., Oshiro, Y., Furue, M., Nakashima, Y., Suzuki, S., Iwaki, T. & Oda, Y., 10 1 2019, : : Virchows Archiv. 475, 4, p. 467-477 11 p.

研究成果: ジャーナルへの寄稿記事

Solitary Fibrous Tumors
Cause of Death
Hypoglycemia
Neoplasms
Central Nervous System

Efficacy and safety of ramucirumab plus modified FOLFIRI for metastatic colorectal cancer

Yoshihiro, T., Kusaba, H., Makiyama, A., Kobayashi, K., Uenomachi, M., Ito, M., Doi, Y., Mitsugi, K., Aikawa, T., Takayoshi, K., Esaki, T., Shimokawa, H., Tsuchihashi, K., Ariyama, H., Akashi, K. & Baba, E., 5 15 2019, : : International Journal of Clinical Oncology. 24, 5, p. 508-515 8 p.

研究成果: ジャーナルへの寄稿記事

Colorectal Neoplasms
Safety
irinotecan
Confidence Intervals
ramucirumab
2 引用 (Scopus)

Endothelial-mesenchymal transition drives expression of CD44 variant and xCT in pulmonary hypertension

Isobe, S., Kataoka, M., Endo, J., Moriyama, H., Okazaki, S., Tsuchihashi, K., Katsumata, Y., Yamamoto, T., Shirakawa, K., Yoshida, N., Shimoda, M., Chiba, T., Masuko, T., Hakamata, Y., Kobayashi, E., Saya, H., Fukuda, K. & Sano, M., 1 1 2019, : : American journal of respiratory cell and molecular biology. 61, 3, p. 367-379 13 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Pulmonary Hypertension
Glutathione
Antioxidants
Chemotherapy

Prognostic scores for evaluating the survival benefit of regorafenib or trifluridine/tipiracil in patients with metastatic colorectal cancer: an exploratory analysis of the REGOTAS study

Moriwaki, T., Fukuoka, S., Masuishi, T., Takashima, A., Kumekawa, Y., Kajiwara, T., Yamazaki, K., Esaki, T., Makiyama, A., Denda, T., Hatachi, Y., Suto, T., Sugimoto, N., Enomoto, M., Ishikawa, T., Kashiwada, T., Oki, E., Komatsu, Y., Tsuji, A., Tsuchihashi, K. および5人, Sakai, D., Ueno, H., Tamura, T., Yamashita, K. & Shimada, Y., 1 1 2019, (受理済み/印刷中) : : International Journal of Clinical Oncology.

研究成果: ジャーナルへの寄稿記事

Trifluridine
Colorectal Neoplasms
Survival
Proportional Hazards Models
regorafenib
2018
9 引用 (Scopus)

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Uchi, H., Ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., 10 2018, : : Cancer Science. 109, 10, p. 3032-3042 11 p.

研究成果: ジャーナルへの寄稿記事

Th1 Cells
Melanoma
T-Lymphocytes
Antibodies
Phenotype
4 引用 (Scopus)

Development of a functional thyroid model based on an organoid culture system

Saito, Y., Onishi, N., Takami, H., Seishima, R., Inoue, H., Hirata, Y., Kameyama, K., Tsuchihashi, K., Sugihara, E., Uchino, S., Ito, K., Kawakubo, H., Takeuchi, H., Kitagawa, Y., Saya, H. & Nagano, O., 3 4 2018, : : Biochemical and Biophysical Research Communications. 497, 2, p. 783-789 7 p.

研究成果: ジャーナルへの寄稿記事

Organoids
Thyroglobulin
Iodides
Cell culture
Thyroid Gland
1 引用 (Scopus)

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., 12 2018, : : Cancer Science. 109, 12, p. 3874-3882 9 p.

研究成果: ジャーナルへの寄稿記事

Glutamate Receptors
Epidermal Growth Factor Receptor
Glioma
Glutamic Acid
Epidermal Growth Factor
1 引用 (Scopus)

Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., Ariyama, H., Mitsugi, K., Makiyama, A., Uchino, K., Esaki, T., Tsuruta, N., Hanamura, F., Yamaguchi, K., Okumura, Y., Sagara, K., Takayoshi, K., Nio, K., Tsuchihashi, K., Tamura, S., Shimokawa, H., Arita, S., Miyawaki, K. および3人, Kusaba, H., Akashi, K. & Baba, E., 11 2018, : : Cancer Science. 109, 11, p. 3461-3470 10 p.

研究成果: ジャーナルへの寄稿記事

Gastrointestinal Neoplasms
Epithelial-Mesenchymal Transition
Ascites
Neoplasms
Transforming Growth Factor beta

Metastatic esophageal carcinosarcoma comprising neuroendocrine carcinoma, squamous cell carcinoma, and sarcoma A case report

Tsuchihashi, K., Arita, S., Fujiwara, M., Iwasaki, K., Hirano, A., Yoshihiro, T., Nio, K., Koga, Y., Esaki, M., Ariyama, H., Kusaba, H., Moriyama, T., Ohuchida, K., Nagai, E., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., 10 1 2018, : : Medicine (United States). 97, 41, e12796.

研究成果: ジャーナルへの寄稿記事

Carcinosarcoma
Neuroendocrine Carcinoma
Sarcoma
Squamous Cell Carcinoma
Etoposide
2 引用 (Scopus)

PD-1+ TIM-3+ T cells in malignant ascites predict prognosis of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., Yamaguchi, K., Ariyama, H., Mitsugi, K., Yoshihiro, T., Ohmura, H., Tsuruta, N., Hanamura, F., Sagara, K., Okumura, Y., Nio, K., Tsuchihashi, K., Arita, S., Kusaba, H., Akashi, K. & Baba, E., 9 2018, : : Cancer Science. 109, 9, p. 2986-2992 7 p.

研究成果: ジャーナルへの寄稿記事

Tumor-Infiltrating Lymphocytes
Gastrointestinal Neoplasms
Ascites
Cell Death
T-Lymphocytes
2 引用 (Scopus)

Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer

Tsuchihashi, K., Ito, M., Moriwaki, T., Fukuoka, S., Taniguchi, H., Takashima, A., Kumekawa, Y., Kajiwara, T., Yamazaki, K., Esaki, T., Makiyama, A., Denda, T., Satake, H., Suto, T., Sugimoto, N., Katsumata, K., Ishikawa, T., Kashiwada, T., Oki, E., Komatsu, Y. および8人, Okuyama, H., Sakai, D., Ueno, H., Tamura, T., Yamashita, K., Kishimoto, J., Shimada, Y. & Baba, E., 12 2018, : : Clinical Colorectal Cancer. 17, 4, p. e687-e697

研究成果: ジャーナルへの寄稿記事

Colorectal Neoplasms
Drug Therapy
Confidence Intervals
Disease-Free Survival
Survival

Successful chemotherapeutic treatment for metastatic littoral cell angioma: A case report

Takayoshi, K., Doi, G., Tsuruta, N., Yoshihiro, T., Nio, K., Tsuchihashi, K., Ariyama, H., Odawara, J., Shimoda, S., Kohashi, K., Oda, Y., Itoh, S., Harimoto, N., Maehara, Y., Kusaba, H., Akashi, K. & Baba, E., 4 1 2018, : : Medicine (United States). 97, 15, e0378.

研究成果: ジャーナルへの寄稿記事

Hepatomegaly
Cytotoxins
Deoxyglucose
Liver
Tomography
3 引用 (Scopus)

The risk factors for oxaliplatin-induced peripheral sensory neuropathy and thrombocytopenia in advanced gastric cancer

Yamaguchi, K., Kusaba, H., Makiyama, A., Mitsugi, K., Uchino, K., Tamura, S., Shibata, Y., Esaki, T., Ito, M., Takayoshi, K., Tsuchihashi, K., Arita, S., Ariyama, H., Akashi, K. & Baba, E., 10 1 2018, : : Cancer chemotherapy and pharmacology. 82, 4, p. 625-633 9 p.

研究成果: ジャーナルへの寄稿記事

oxaliplatin
Peripheral Nervous System Diseases
Thrombocytopenia
Stomach Neoplasms
Medical problems
2017
4 引用 (Scopus)

CD44 variant–dependent regulation of redox balance in EGFR mutation–positive non–small cell lung cancer: A target for treatment

Kawano, Y., Iwama, E., Tsuchihashi, K., Shibahara, D., Harada, T., Tanaka, K., Nagano, O., Saya, H., Nakanishi, Y. & Okamoto, I., 11 2017, : : Lung Cancer. 113, p. 72-78 7 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Oxidation-Reduction
Reactive Oxygen Species
Cisplatin
30 引用 (Scopus)

Dose-escalation study for the targeting of CD44v+ cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205)

Shitara, K., Doi, T., Nagano, O., Imamura, C. K., Ozeki, T., Ishii, Y., Tsuchihashi, K., Takahashi, S., Nakajima, T. E., Hironaka, S., Fukutani, M., Hasegawa, H., Nomura, S., Sato, A., Einaga, Y., Kuwata, T., Saya, H. & Ohtsu, A., 3 1 2017, : : Gastric Cancer. 20, 2, p. 341-349 9 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Neoplastic Stem Cells
Stomach Neoplasms
Biopsy
Oxidative Stress
1 引用 (Scopus)

Lingual alveolar soft part sarcoma responsive to pazopanib: A case report

Yoshihiro, T., Tsuchihashi, K., Nio, K., Arita, S., Nakano, T., Yasumatsu, R., Jiroumaru, R., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., 11 2017, : : Medicine (United States). 96, 44, e8470.

研究成果: ジャーナルへの寄稿記事

Alveolar Soft Part Sarcoma
Tongue
Articulation Disorders
Lung
Ifosfamide

Metastatic esophageal cancer presenting as shock by injury of vagus nerve mimicking baroreceptor reflex: A case report

Tsuchihashi, K., Yoshihiro, T., Aikawa, T., Nio, K., Takayoshi, K., Yokoyama, T., Fukata, M., Arita, S., Ariyama, H., Shimizu, Y., Yoshida, Y., Torisu, T., Esaki, M., Odashiro, K., Kusaba, H., Akashi, K. & Baba, E., 12 1 2017, : : Medicine (United States). 96, 49, e8987.

研究成果: ジャーナルへの寄稿記事

Vagus Nerve Injuries
Baroreflex
Esophageal Neoplasms
Vagus Nerve
Shock
12 引用 (Scopus)

Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407)

Shitara, K., Doi, T., Nagano, O., Fukutani, M., Hasegawa, H., Nomura, S., Sato, A., Kuwata, T., Asai, K., Einaga, Y., Tsuchihashi, K., Suina, K., Maeda, Y., Saya, H. & Ohtsu, A., 11 1 2017, : : Gastric Cancer. 20, 6, p. 1004-1009 6 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Cisplatin
Stomach Neoplasms
Amino Acid Transport System X-AG
Cystine
8 引用 (Scopus)

Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non-small-cell lung cancer

Otsubo, K., Nosaki, K., Imamura, C. K., Ogata, H., Fujita, A., Sakata, S., Hirai, F., Toyokawa, G., Iwama, E., Harada, T., Seto, T., Takenoyama, M., Ozeki, T., Mushiroda, T., Inada, M., Kishimoto, J., Tsuchihashi, K., Suina, K., Nagano, O., Saya, H. および2人, Nakanishi, Y. & Okamoto, I., 9 2017, : : Cancer Science. 108, 9, p. 1843-1849 7 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
Sulfasalazine
Non-Small Cell Lung Carcinoma
Cisplatin
Neoplastic Stem Cells

Regorafenib-induced retinal and gastrointestinal hemorrhage in a metastatic colorectal cancer patient with liver dysfunction

Tsuchihashi, K., Shimokawa, H., Takayoshi, K., Nio, K., Aikawa, T., Matsushita, Y., Wada, I., Arita, S., Ariyama, H., Kusaba, H., Sonoda, K. H., Akashi, K. & Baba, E., 10 1 2017, : : Medicine (United States). 96, 42, e8285.

研究成果: ジャーナルへの寄稿記事

Retinal Hemorrhage
Gastrointestinal Hemorrhage
Liver Diseases
Colorectal Neoplasms
Hemorrhage
9 引用 (Scopus)

Suggestion of added value by bevacizumab to chemotherapy in patients with unresectable or recurrent small bowel cancer

Takayoshi, K., Kusaba, H., Uenomachi, M., Mitsugi, K., Makiyama, C., Makiyama, A., Uchino, K., Shirakawa, T., Shibata, Y., Shinohara, Y., Inadomi, K., Tsuchihashi, K., Arita, S., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., 8 1 2017, : : Cancer chemotherapy and pharmacology. 80, 2, p. 333-342 10 p.

研究成果: ジャーナルへの寄稿記事

Intestinal Neoplasms
Chemotherapy
Drug Therapy
Adenocarcinoma
oxaliplatin
2016
24 引用 (Scopus)

Current cigarette smoking is a reversible cause of elevated white blood cell count: Cross-sectional and longitudinal studies

Higuchi, T., Omata, F., Tsuchihashi, K., Higashioka, K., Koyamada, R. & Okada, S., 12 1 2016, : : Preventive Medicine Reports. 4, p. 417-422 6 p.

研究成果: ジャーナルへの寄稿記事

Leukocyte Count
Longitudinal Studies
Cross-Sectional Studies
Smoking
Smoking Cessation
11 引用 (Scopus)

Development of an ErbB4 monoclonal antibody that blocks neuregulin-1-induced ErbB4 activation in cancer cells

Okazaki, S., Nakatani, F., Masuko, K., Tsuchihashi, K., Ueda, S., Masuko, T., Saya, H. & Nagano, O., 1 29 2016, : : Biochemical and Biophysical Research Communications. 470, 1, p. 239-244 6 p.

研究成果: ジャーナルへの寄稿記事

Neuregulin-1
Chemical activation
Monoclonal Antibodies
Cells
Cell proliferation
6 引用 (Scopus)

Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines

Wang, M., Miura, Y., Tsuchihashi, K., Miyano, K., Nagano, O., Yoshikawa, M., Tanabe, A., Makino, J., Mochida, Y., Nishiyama, N., Saya, H., Cabral, H. & Kataoka, K., 5 28 2016, : : Journal of Controlled Release. 230, p. 26-33 8 p.

研究成果: ジャーナルへの寄稿記事

Nanomedicine
Cisplatin
Neck
Head
Neoplastic Stem Cells
24 引用 (Scopus)

The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)

Tsuchihashi, K., Okazaki, S., Ohmura, M., Ishikawa, M., Sampetrean, O., Onishi, N., Wakimoto, H., Yoshikawa, M., Seishima, R., Iwasaki, Y., Morikawa, T., Abe, S., Takao, A., Shimizu, M., Masuko, T., Nagane, M., Furnari, F. B., Akiyama, T., Suematsu, M., Baba, E. および3人, Akashi, K., Saya, H. & Nagano, O., 5 15 2016, : : Cancer Research. 76, 10, p. 2954-2963 10 p.

研究成果: ジャーナルへの寄稿記事

Amino Acid Transport Systems
Epidermal Growth Factor Receptor
Glioma
Cystine
Glutamic Acid
2015
13 引用 (Scopus)

Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry

Ohmura, M., Hishiki, T., Yamamoto, T., Nakanishi, T., Kubo, A., Tsuchihashi, K., Tamada, M., Toue, S., Kabe, Y., Saya, H. & Suematsu, M., 4 30 2015, : : Nitric Oxide - Biology and Chemistry. 46, p. 102-113 12 p.

研究成果: ジャーナルへの寄稿記事

Mass spectrometry
Tumors
Mass Spectrometry
Cells
Imaging techniques
10 引用 (Scopus)

Ink4a/arf-dependent loss of parietal cells induced by oxidative stress promotes CD44-dependent gastric tumorigenesis

Seishima, R., Wada, T., Tsuchihashi, K., Okazaki, S., Yoshikawa, M., Oshima, H., Oshima, M., Sato, T., Hasegawa, H., Kitagawa, Y., Goldenring, J. R., Saya, H. & Nagano, O., 6 1 2015, : : Cancer Prevention Research. 8, 6, p. 492-501 10 p.

研究成果: ジャーナルへの寄稿記事

Stomach
Carcinogenesis
Oxidative Stress
Reactive Oxygen Species
Metaplasia
2 引用 (Scopus)

Successful treatment of adult Langerhans cell histiocytosis with intensified chemotherapy

Minami, M., Shima, T., Kato, K., Yamamoto, H., Tsuchihashi, K., Oku, S., Shimokawa, T., Tochigi, T., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H., Oda, Y., Miyamoto, T. & Akashi, K., 8 11 2015, : : International journal of hematology. 102, 2, p. 244-248 5 p.

研究成果: ジャーナルへの寄稿記事

Langerhans Cell Histiocytosis
Drug Therapy
Pediatrics
Therapeutics
Clinical Protocols
2014
4 引用 (Scopus)

Interstitial pneumonia during bevacizumab-based chemotherapy for colorectal cancer

Tamura, S., Kusaba, H., Kubo, N., Ijichi, K., Tsuchihashi, K., Komoda, M., Uchino, K., Ariyama, H., Akashi, K. & Baba, E., 1 1 2014, : : Medical Oncology. 31, 3, 856.

研究成果: ジャーナルへの寄稿記事

Interstitial Lung Diseases
Colorectal Neoplasms
Drug Therapy
Lung
Pharmaceutical Preparations
2013
50 引用 (Scopus)

Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia

Wada, T., Ishimoto, T., Seishima, R., Tsuchihashi, K., Yoshikawa, M., Oshima, H., Oshima, M., Masuko, T., Wright, N. A., Furuhashi, S., Hirashima, K., Baba, H., Kitagawa, Y., Saya, H. & Nagano, O., 10 1 2013, : : Cancer Science. 104, 10, p. 1323-1329 7 p.

研究成果: ジャーナルへの寄稿記事

Metaplasia
Stomach
Cystine
Neoplasms
Carcinogenesis
97 引用 (Scopus)

XCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma

Yoshikawa, M., Tsuchihashi, K., Ishimoto, T., Yae, T., Motohara, T., Sugihara, E., Onishi, N., Masuko, T., Yoshizawa, K., Kawashiri, S., Mukai, M., Asoda, S., Kawana, H., Nakagawa, T., Saya, H. & Nagano, O., 3 15 2013, : : Cancer Research. 73, 6, p. 1855-1866 12 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Neoplasms
Cystine
Therapeutics
Neoplastic Stem Cells
2012
183 引用 (Scopus)

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

Yae, T., Tsuchihashi, K., Ishimoto, T., Motohara, T., Yoshikawa, M., Yoshida, G. J., Wada, T., Masuko, T., Mogushi, K., Tanaka, H., Osawa, T., Kanki, Y., Minami, T., Aburatani, H., Ohmura, M., Kubo, A., Suematsu, M., Takahashi, K., Saya, H. & Nagano, O., 7 6 2012, : : Nature communications. 3, 883.

研究成果: ジャーナルへの寄稿記事

splicing
Alternative Splicing
metastasis
lungs
cancer