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研究成果 1985 2019

  • 1287 引用
  • 13 h指数
  • 33 記事
  • 3 レター
  • 1 評論記事
2019

Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer

Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y., 2 1 2019, : : Anticancer research. 39, 2, p. 671-677 7 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Therapeutics
Exome

Immune checkpoint protein and cytokine expression by T lymphocytes in pleural effusion of cancer patients receiving anti–PD-1 therapy

Ikematsu, Y., Tanaka, K., Yanagihara, T., Liu, R., Inoue, H., Yoneshima, Y., Ota, K., Iwama, E., Takata, S., Hata, K., Takahata, Y., Wataya, H., Nakanishi, Y. & Okamoto, I., 12 2019, : : Lung Cancer. 138, p. 58-64 7 p.

研究成果: ジャーナルへの寄稿記事

Pleural Effusion
Cell Death
Cytokines
T-Lymphocytes
Neoplasms

Phase I safety and pharmacokinetics study of rovalpituzumab tesirine in Japanese patients with advanced, recurrent small cell lung cancer

Udagawa, H., Akamatsu, H., Tanaka, K., Takeda, M., Kanda, S., Kirita, K., Teraoka, S., Nakagawa, K., Fujiwara, Y., Yasuda, I., Okubo, S., Shintani, M., Kosloski, M. P., Scripture, C., Tamura, T. & Okamoto, I., 9 1 2019, : : Lung Cancer. 135, p. 145-150 6 p.

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
Pharmacokinetics
Safety
Hypoalbuminemia
Retreatment
2 引用 (Scopus)

Safety and efficacy of PD-1 inhibitors in non–small cell lung cancer patients positive for antinuclear antibodies

Yoneshima, Y., Tanaka, K., Shiraishi, Y., Hata, K., Watanabe, H., Harada, T., Otsubo, K., Iwama, E., Inoue, H., Masuda, S., Nakanishi, Y. & Okamoto, I., 4 1 2019, : : Lung Cancer. 130, p. 5-9 5 p.

研究成果: ジャーナルへの寄稿記事

Antinuclear Antibodies
Non-Small Cell Lung Carcinoma
Safety
Autoimmune Diseases
Disease-Free Survival

The Japanese Lung Cancer Society Guideline for non-small cell lung cancer, stage IV

Akamatsu, H., Ninomiya, K., Kenmotsu, H., Morise, M., Daga, H., Goto, Y., Kozuki, T., Miura, S., Sasaki, T., Tamiya, A., Teraoka, S., Tsubata, Y., Yoshioka, H., Hattori, Y., Imamura, C. K., Katsuya, Y., Matsui, R., Minegishi, Y., Mizugaki, H., Nosaki, K. および13人, Okuma, Y., Sakamoto, S., Sone, T., Tanaka, K., Umemura, S., Yamanaka, T., Amano, S., Hasegawa, K., Morita, S., Nakajima, K., Maemondo, M., Seto, T. & Yamamoto, N., 7 12 2019, : : International Journal of Clinical Oncology. 24, 7, p. 731-770 40 p.

研究成果: ジャーナルへの寄稿記事

公開
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Guidelines
Japan
Patient Advocacy
2018

Association of nephrotoxicity during platinum-etoposide doublet therapy with UGT1A1 polymorphisms in small cell lung cancer patients

Anai, S., Iwama, E., Yoneshima, Y., Otsubo, K., Tanaka, K., Nakanishi, Y. & Okamoto, I., 12 1 2018, : : Lung Cancer. 126, p. 156-161 6 p.

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
Etoposide
Platinum
Alleles
irinotecan
2 引用 (Scopus)

Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade

Tanaka, K., Yanagihara, T., Ikematsu, Y., Inoue, H., Ota, K., Kashiwagi, E., Suzuki, K., Hamada, N., Takeuchi, A., Tatsugami, K., Eto, M., Ijichi, K., Oda, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., 7 17 2018, : : Oncotarget. 9, 55, p. 30587-30593 7 p.

研究成果: ジャーナルへの寄稿記事

Bronchoalveolar Lavage Fluid
Pleural Effusion
Pneumonia
Clone Cells
T-Cell Antigen Receptor
2 引用 (Scopus)

Durable response to nivolumab in a lung adenocarcinoma patient with idiopathic pulmonary fibrosis

Ide, M., Tanaka, K., Sunami, S., Asoh, T., Maeyama, T., Tsuruta, N., Nakanishi, Y. & Okamoto, I., 11 1 2018, : : Thoracic Cancer. 9, 11, p. 1519-1521 3 p.

研究成果: ジャーナルへの寄稿記事

Idiopathic Pulmonary Fibrosis
Non-Small Cell Lung Carcinoma
Pleurisy
Respiratory Function Tests
Neoplasms
2 引用 (Scopus)

Expression of brain-derived neurotrophic factor and its receptor TrkB is associated with poor prognosis and a malignant phenotype in small cell lung cancer

Kimura, S., Harada, T., Ijichi, K., Tanaka, K., Liu, R., Shibahara, D., Kawano, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., 6 1 2018, : : Lung Cancer. 120, p. 98-107 10 p.

研究成果: ジャーナルへの寄稿記事

trkB Receptor
Brain-Derived Neurotrophic Factor
Small Cell Lung Carcinoma
Phenotype
Non-Small Cell Lung Carcinoma

Expression of PD-1 and PD-L1 on cytotoxic T lymphocytes and immune deficiency in a patient with adult T cell leukemia/lymphoma

Yanagihara, T., Ikematsu, Y., Kato, K., Yonekawa, A., Ideishi, S., Tochigi, T., Sugio, T., Miyawaki, K., Tanaka, K., Harada, E., Hamada, N. & Nakanishi, Y., 2 1 2018, : : Annals of Hematology. 97, 2, p. 359-360 2 p.

研究成果: ジャーナルへの寄稿レター

Adult T Cell Leukemia Lymphoma
Cytotoxic T-Lymphocytes
5 引用 (Scopus)

Intrinsic and Extrinsic Regulation of PD-L2 Expression in Oncogene-Driven Non–Small Cell Lung Cancer

Shibahara, D., Tanaka, K., Iwama, E., Kubo, N., ota, K., Azuma, K., Harada, T., Fujita, J., Nakanishi, Y. & Okamoto, I., 7 1 2018, : : Journal of Thoracic Oncology. 13, 7, p. 926-937 12 p.

研究成果: ジャーナルへの寄稿記事

Oncogenes
Non-Small Cell Lung Carcinoma
Cell Death
Ligands
STAT3 Transcription Factor
13 引用 (Scopus)

PD-L1 expression in lung adenocarcinoma harboring EGFR mutations or ALK rearrangements

Yoneshima, Y., Ijichi, K., Anai, S., ota, K., Otsubo, K., Iwama, E., Tanaka, K., Oda, Y., Nakanishi, Y. & Okamoto, I., 4 1 2018, : : Lung Cancer. 118, p. 36-40 5 p.

研究成果: ジャーナルへの寄稿記事

Mutation
Neoplasms
Adenocarcinoma of lung
Protein-Tyrosine Kinases
Oncogenes
14 引用 (Scopus)

Prevalence of Delta-like protein 3 expression in patients with small cell lung cancer

Tanaka, K., Isse, K., Fujihira, T., Takenoyama, M., Saunders, L., Bheddah, S., Nakanishi, Y. & Okamoto, I., 1 1 2018, : : Lung Cancer. 115, p. 116-120 5 p.

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
delta protein
Neoplasms
Sex Characteristics
Japan
4 引用 (Scopus)

Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3

Tanaka, K., Martinez, G. J., Yan, X., Long, W., Ichiyama, K., Chi, X., Kim, B. S., Reynolds, J. M., Chung, Y., Tanaka, S., Liao, L., Nakanishi, Y., Yoshimura, A., Zheng, P., Wang, X., Tian, Q., Xu, J., O'Malley, B. W. & Dong, C., 5 22 2018, : : Cell Reports. 23, 8, p. 2318-2329 12 p.

研究成果: ジャーナルへの寄稿記事

Nuclear Receptor Coactivator 3
Th17 Cells
Cell Differentiation
Interleukin-1
Interleukin-6

Sensitivity of epidermal growth factor receptor with single or double uncommon mutations to afatinib confirmed by a visual assay

Kimura, S., Tanaka, K., Harada, T., Liu, R., Shibahara, D., Kawano, Y., Nakanishi, Y. & Okamoto, I., 11 1 2018, : : Cancer Science. 109, 11, p. 3657-3661 5 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Mutation
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
BIBW 2992
10 引用 (Scopus)

Trim33 mediates the proinflammatory function of Th17 cells

Tanaka, S., Jiang, Y., Martinez, G. J., Tanaka, K., Yan, X., Kurosaki, T., Kaartinen, V., Feng, X. H., Tian, Q., Wang, X. & Dong, C., 7 1 2018, : : Journal of Experimental Medicine. 215, 7, p. 1853-1868 16 p.

研究成果: ジャーナルへの寄稿記事

Th17 Cells
Interleukin-10
Transforming Growth Factors
Chromatin Assembly and Disassembly
Interleukin-17
2017
4 引用 (Scopus)

CD44 variant–dependent regulation of redox balance in EGFR mutation–positive non–small cell lung cancer: A target for treatment

Kawano, Y., Iwama, E., Tsuchihashi, K., Shibahara, D., Harada, T., Tanaka, K., Nagano, O., Saya, H., Nakanishi, Y. & Okamoto, I., 11 1 2017, : : Lung Cancer. 113, p. 72-78 7 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Oxidation-Reduction
Reactive Oxygen Species
Cisplatin
25 引用 (Scopus)

Generation of RORγt + Antigen-Specific T Regulatory 17 Cells from Foxp3 + Precursors in Autoimmunity

Kim, B. S., Lu, H., Ichiyama, K., Chen, X., Zhang, Y. B., Mistry, N. A., Tanaka, K., Lee, Y. H., Nurieva, R., Zhang, L., Yang, X., Chung, Y., Jin, W., Chang, S. H. & Dong, C., 10 3 2017, : : Cell Reports. 21, 1, p. 195-207 13 p.

研究成果: ジャーナルへの寄稿記事

Regulatory T-Lymphocytes
Autoimmunity
Immunization
Antigens
T-cells
7 引用 (Scopus)

Marked response to pembrolizumab in a patient with pulmonary pleomorphic carcinoma highly positive for PD-L1

Ikematsu, Y., Yoneshima, Y., Ijichi, K., Tanaka, K., Harada, T., Oda, Y., Nakanishi, Y. & Okamoto, I., 10 1 2017, : : Lung Cancer. 112, p. 230-231 2 p.

研究成果: ジャーナルへの寄稿レター

Carcinoma
Lung
pembrolizumab
16 引用 (Scopus)

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., 6 1 2017, : : Lung Cancer. 108, p. 75-82 8 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Alleles
Mutation
Protein-Tyrosine Kinases
3 引用 (Scopus)
2015
33 引用 (Scopus)

Batf is important for IL-4 expression in T follicular helper cells

Sahoo, A., Alekseev, A., Tanaka, K., Obertas, L., Lerman, B., Haymaker, C., Clise-Dwyer, K., McMurray, J. S. & Nurieva, R., 8 17 2015, : : Nature communications. 6, 7997.

研究成果: ジャーナルへの寄稿記事

Helper-Inducer T-Lymphocytes
Interleukin-4
cells
Th2 Cells
Basic-Leucine Zipper Transcription Factors
2014
4 引用 (Scopus)

CCAAT/enhancer-binding protein α negatively regulates IFN-γ expression in T cells

Tanaka, S., Tanaka, K., Magnusson, F., Chung, Y., Martinez, G. J., Wang, Y. H., Nurieva, R. I., Kurosaki, T. & Dong, C., 12 15 2014, : : Journal of Immunology. 193, 12, p. 6152-6160 9 p.

研究成果: ジャーナルへの寄稿記事

CCAAT-Enhancer-Binding Proteins
Helper-Inducer T-Lymphocytes
T-Lymphocytes
Basic-Leucine Zipper Transcription Factors
Immunoglobulin Class Switching
2013
33 引用 (Scopus)

Nicotine induces resistance to epidermal growth factor receptor tyrosine kinase inhibitor by α1 nicotinic acetylcholine receptor-mediated activation in PC9 cells

Wang, S., Takayama, K., Tanaka, K., Takeshita, M., Nakagaki, N., Ijichi, K., Li, H. & Nakanishi, Y., 1 1 2013, : : Journal of Thoracic Oncology. 8, 6, p. 719-725 7 p.

研究成果: ジャーナルへの寄稿記事

Nicotinic Receptors
Nicotine
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
2012
8 引用 (Scopus)

IL-6 induced by double-stranded RNA augments allergic inflammation via suppression of Foxp3+T-cell/IL-10 axis

Matsumoto, K., Asai, Y., Fukuyama, S., Kan-o, K., Matsunaga, Y., Noda, N., Kitajima, H., Tanaka, K., Nakanishi, Y. & Inoue, H., 6 1 2012, : : American journal of respiratory cell and molecular biology. 46, 6, p. 740-747 8 p.

研究成果: ジャーナルへの寄稿記事

Galactosamine
T-cells
Double-Stranded RNA
Poly C
Interleukin-10
2010
1 引用 (Scopus)

[A case of non-small cell lung cancer with hemodialysis which responded to docetaxel monotherapy].

Abe, Y., Tanaka, K., Matsumoto, K., Takayama, K., Inoue, H., Izumi, M., Inoue, H. & Nakanishi, Y., 1 1 2010, : : Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 48, 10, p. 769-773 5 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Non-Small Cell Lung Carcinoma
Renal Dialysis
Pleural Effusion
Drug Therapy
2009
521 引用 (Scopus)

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

Lu, L. F., Thai, T. H., Calado, D. P., Chaudhry, A., Kubo, M., Tanaka, K., Loeb, G. B., Lee, H., Yoshimura, A., Rajewsky, K. & Rudensky, A. Y., 1 16 2009, : : Immunity. 30, 1, p. 80-91 12 p.

研究成果: ジャーナルへの寄稿記事

Regulatory T-Lymphocytes
MicroRNAs
STAT5 Transcription Factor
Cytokines
Autoantigens

Paraneoplastic brainstem encephalitis and subacute sensory neuropathy presenting various neurological symptoms associated with small cell lung cancer

Kudo, K., Izumi, M., Takayama, K., Fukuyama, S., Tanaka, K. & Nakanishi, Y., 10 1 2009, : : Japanese Journal of Lung Cancer. 49, 6, p. 852-856 5 p.

研究成果: ジャーナルへの寄稿記事

Paraneoplastic Syndromes
Small Cell Lung Carcinoma
Encephalitis
Brain Stem
Blepharoptosis
25 引用 (Scopus)

Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype

Fukuyama, S., Nakano, T., Matsumoto, T., Oliver, B. G. G., Burgess, J. K., Moriwaki, A., Tanaka, K., Kubo, M., Hoshino, T., Tanaka, H., McKenzie, A. N. J., Matsumoto, K., Aizawa, H., Nakanishi, Y., Yoshimura, A., Black, J. L. & Inoue, H., 6 1 2009, : : American Journal of Respiratory and Critical Care Medicine. 179, 11, p. 992-998 7 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-13
Asthma
Cytokines
Phenotype
Lung
2008
124 引用 (Scopus)

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-γ on STAT3 and Smads

Tanaka, K., Ichiyama, K., Hashimoto, M., Yoshida, H., Takimoto, T., Takaesu, G., torisu, T., Hanada, T., Yasukawa, H., Fukuyama, S., Inoue, H., Nakanishi, Y., Kobayashi, T. & Yoshimura, A., 3 15 2008, : : Journal of Immunology. 180, 6, p. 3746-3756 11 p.

研究成果: ジャーナルへの寄稿記事

Th1 Cells
Cytokines
T-Lymphocytes
Phenotype
Retinoic Acid Receptors
57 引用 (Scopus)

Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice

Horino, J., Fujimoto, M., Terabe, F., Serada, S., Takahashi, T., Soma, Y., Tanaka, K., Chinen, T., Yoshimura, A., Nomura, S., Kawase, I., Hayashi, N., Kishimoto, T. & Naka, T., 6 1 2008, : : International Immunology. 20, 6, p. 753-762 10 p.

研究成果: ジャーナルへの寄稿記事

Dextran Sulfate
Colitis
Cytokines
Inflammatory Bowel Diseases
Regulatory T-Lymphocytes
2007

Intracellular negative signals and allergy

Yoshimura, A., Tanaka, K., Okamoto, F. & Kobayashi, T., 1 1 2007, : : Arerugī = [Allergy]. 56, 6, p. 563-569 7 p.

研究成果: ジャーナルへの寄稿評論記事

Suppressor of Cytokine Signaling Proteins
Helper-Inducer T-Lymphocytes
Signal Transduction
Hypersensitivity
Cytokines
89 引用 (Scopus)

Selective expansion of Foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells

Matsumura, Y., Kobayashi, T., Ichiyama, K., Yoshida, R., Hashimoto, M., Takimoto, T., Tanaka, K., Chinen, T., Shichita, T., Wyss-Coray, T., Sato, K. & Yoshimura, A., 8 15 2007, : : Journal of Immunology. 179, 4, p. 2170-2179 10 p.

研究成果: ジャーナルへの寄稿記事

Regulatory T-Lymphocytes
Immunosuppression
Dendritic Cells
Cytokines
T-Lymphocytes
2006
29 引用 (Scopus)

The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia

Moriyama, M., Fukuyama, S., Inoue, H., Matsumoto, T., Sato, T., Tanaka, K., Kinjyo, I., Kano, T., Yoshimura, A. & Kojima, M., 5 1 2006, : : American Journal of Physiology - Lung Cellular and Molecular Physiology. 290, 5

研究成果: ジャーナルへの寄稿記事

Eosinophilia
Neuropeptides
Eosinophils
Allergens
neuromedin U
2005
77 引用 (Scopus)

Induction of hyper Th1 cell-type immune responses by dendritic cells lacking the suppressor of cytokine signaling-1 gene

Hanada, T., Tanaka, K., Matsumura, Y., Yamauchi, M., Nishinakamura, H., Aburatani, H., Mashima, R., Kubo, M., Kobayashi, T. & Yoshimura, A., 4 1 2005, : : Journal of Immunology. 174, 7, p. 4325-4332 8 p.

研究成果: ジャーナルへの寄稿記事

Th1 Cells
Dendritic Cells
Cytokines
Bone Marrow
Genes
2003
176 引用 (Scopus)

Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity

Hanada, T., Yoshida, H., Kato, S., Tanaka, K., Masutani, K., Tsukada, J., Nomura, Y., Mimata, H., Kubo, M. & Yoshimura, A., 9 1 2003, : : Immunity. 19, 3, p. 437-450 14 p.

研究成果: ジャーナルへの寄稿記事

Autoimmunity
Dendritic Cells
Cytokines
B-Lymphocytes
Macrophage Activation
1985
1 引用 (Scopus)

A case of lung carcinoma associated with production of human chorionic gonadotropin

Ninomiya, K., Shigematu, N. & Tanaka, K., 1 1 1985, : : Japanese Journal of Thoracic Diseases. 23, 5, p. 599-604 6 p.

研究成果: ジャーナルへの寄稿記事