• 25199 引用
  • 79 h指数
1988 …2020
Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1988 2020

2009
21 引用 (Scopus)

The impact of cytogenetic abnormalities on the prognosis of primary myelofibrosis: A prospective survey of 202 cases in Japan

Hidaka, T., Shide, K., Shimoda, H., Kameda, T., Toyama, K., Katayose, K., Kubuki, Y., Nagata, K., Takenaka, K., Akashi, K., Okamura, T., Niho, Y., Mizoguchi, H., Omine, M., Ozawa, K., Harada, M. & Shimoda, K., 10 1 2009, : : European Journal of Haematology. 83, 4, p. 328-333 6 p.

研究成果: ジャーナルへの寄稿記事

Primary Myelofibrosis
Chromosome Aberrations
Japan
Cytogenetics
Abnormal Karyotype
73 引用 (Scopus)

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

Mercher, T., Raffel, G. D., Moore, S. A., Cornejo, M. G., Baudry-Bluteau, D., Cagnard, N., Jesneck, J. L., Pikman, Y., Cullen, D., Williams, I. R., Akashi, K., Shigematsu, H., Bourquin, J. P., Giovannini, M., Vainchenker, W., Levine, R. L., Lee, B. H., Bernard, O. A. & Gilliland, D. G., 4 1 2009, : : Journal of Clinical Investigation. 119, 4, p. 852-864 13 p.

研究成果: ジャーナルへの寄稿記事

Oncogene Fusion
Leukemia, Megakaryoblastic, Acute
Thrombopoietin Receptors
Megakaryocyte Progenitor Cells
Cell Lineage
2008
60 引用 (Scopus)

Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage

Cantor, A. B., Iwasaki, H., Arinobu, Y., Moran, T. B., Shigematsu, H., Sullivan, M. R., Akashi, K. & Orkin, S. H., 3 17 2008, : : Journal of Experimental Medicine. 205, 3, p. 611-624 14 p.

研究成果: ジャーナルへの寄稿記事

GATA Transcription Factors
Cell Lineage
Mast Cells
Down-Regulation
Gene Regulatory Networks
10 引用 (Scopus)

Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice

Akashi, T., Shigematsu, H., Hamamoto, Y., Iwasaki, H., Yatoh, S., Bonner-Weir, S., Akashi, K. & Weir, G. C., 12 1 2008, : : Diabetes/Metabolism Research and Reviews. 24, 7, p. 585-590 6 p.

研究成果: ジャーナルへの寄稿記事

Regeneration
Bone Marrow
Liver
Green Fluorescent Proteins
Chimerism
54 引用 (Scopus)

CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis

Shimoda, S., Miyakawa, H., Nakamura, M., Ishibashi, H., Kikuchi, K., Kita, H., Niiro, H., Arinobu, Y., Ono, N., Mackay, I. R., Gershwin, M. E. & Akashi, K., 9 1 2008, : : Journal of Autoimmunity. 31, 2, p. 110-115 6 p.

研究成果: ジャーナルへの寄稿記事

Biliary Liver Cirrhosis
Anti-Idiotypic Antibodies
T-Lymphocytes
Interleukin-10
T-Lymphocyte Epitopes
11 引用 (Scopus)

Dendritic cell therapy in combination with interferon-α for the treatment of metastatic renal cell carcinoma

Tatsugami, K., Eto, M., Harano, M., Hamaguchi, M., Miyamoto, T., Morisaki, T., Furue, M., Akashi, K. & Naito, S., 8 1 2008, : : International Journal of Urology. 15, 8, p. 694-698 5 p.

研究成果: ジャーナルへの寄稿記事

Cell- and Tissue-Based Therapy
Renal Cell Carcinoma
Dendritic Cells
Interferons
Delayed Hypersensitivity
61 引用 (Scopus)

Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival

Shono, T., Yokoyama, N., Uesaka, T., Kuroda, J., Takeya, R., Yamasaki, T., Amano, T., Mizoguchi, M., Suzuki, S. O., Niiro, H., Miyamoto, K., Akashi, K., Iwaki, T., Sumimoto, H. & Sasaki, T., 8 15 2008, : : International Journal of Cancer. 123, 4, p. 787-792 6 p.

研究成果: ジャーナルへの寄稿記事

NADPH Oxidase
Glioma
Cell Survival
Astrocytoma
Cell Proliferation
92 引用 (Scopus)

Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival

Kikushige, Y., Yoshimoto, G., Miyamoto, T., Iino, T., Mori, Y., Iwasaki, H., Niiro, H., Takenaka, K., Nagafuji, K., Harada, M., Ishikawa, F. & Akashi, K., 1 1 2008, : : Journal of Immunology. 180, 11, p. 7358-7367 10 p.

研究成果: ジャーナルへの寄稿記事

Granulocyte-Macrophage Progenitor Cells
Hematopoietic Stem Cells
Cell Survival
Hematopoiesis
Acute Myeloid Leukemia

Online First publication

Suda, T., Akashi, K., Lu, D. P., Kim, C. C., Issaragrisil, S. & Hoelzer, D. F., 1 1 2008, : : International journal of hematology. 87, 1, 1 p.

研究成果: ジャーナルへの寄稿編集

Publications
22 引用 (Scopus)

Successful treatment of parainfluenza virus 3 pneumonia with oral ribavirin and methylprednisolone in a bone marrow transplant recipient

Shima, T., Yoshimoto, G., Nonami, A., Yoshida, S., Kamezaki, K., Iwasaki, H., Takenaka, K., Miyamoto, T., Harada, N., Teshima, T., Akashi, K. & Nagafuji, K., 10 1 2008, : : International journal of hematology. 88, 3, p. 336-340 5 p.

研究成果: ジャーナルへの寄稿記事

Paramyxoviridae Infections
Ribavirin
Methylprednisolone
Pneumonia
Bone Marrow
2007
4 引用 (Scopus)

Cartography of hematopoietic stem cell commitment dependent upon a reporter for transcription factor activation

Akashi, K., 1 1 2007, Hematopoietic Stem Cells VI. Blackwell Publishing Inc., p. 76-81 6 p. (Annals of the New York Academy of Sciences; 巻数 1106).

研究成果: 著書/レポートタイプへの貢献会議での発言

Hematopoietic Stem Cells
Stem cells
Transcriptional Activation
Transcription Factors
Chemical activation
580 引用 (Scopus)

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region

Ishikawa, F., Yoshida, S., Saito, Y., Hijikata, A., Kitamura, H., Tanaka, S., Nakamura, R., Tanaka, T., Tomiyama, H., Saito, N., Fukata, M., Miyamoto, T., Lyons, B., Ohshima, K., Uchida, N., Taniguchi, S., Ohara, O., Akashi, K., Harada, M. & Shultz, L. D., 11 1 2007, : : Nature Biotechnology. 25, 11, p. 1315-1321 7 p.

研究成果: ジャーナルへの寄稿記事

Chemotherapy
Stem cells
Acute Myeloid Leukemia
Bone
Stem Cells
2 引用 (Scopus)

Collection of mobilized peripheral blood stem cells from a donor with severe iron deficient anemia

Kamezaki, K., Miyamoto, T., Henzan, T., Numata, A., Iwasaki, H., Nagafuji, K., Harada, M., Teshima, T. & Akashi, K., 11 1 2007, : : Journal of Clinical Apheresis. 22, 5, p. 292-294 3 p.

研究成果: ジャーナルへの寄稿記事

Anemia
Iron
Tissue Donors
Erythrocytes
Hematocrit
32 引用 (Scopus)

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue

Alcaide, P., Jones, T. G., Lord, G. M., Glimcher, L. H., Hallgren, J., Arinobu, Y., Akashi, K., Paterson, A. M., Gurish, M. A. & Luscinskas, F. W., 2 1 2007, : : Journal of Experimental Medicine. 204, 2, p. 431-439 9 p.

研究成果: ジャーナルへの寄稿記事

Mast Cells
Dendritic Cells
Mucous Membrane
Vascular Cell Adhesion Molecule-1
Bone Marrow
17 引用 (Scopus)

Distinctive expression of myelomonocytic markers and down-regulation of CD34 in acute myelogenous leukaemia with FLT3 tandem duplication and nucleophosmin mutation

Mori, Y., Yoshimoto, G., Kumano, T., Miyamoto, T., Iino, T., Takenaka, K., Iwasaki, H., Harada, N., Kinukawa, N., Nagafuji, K., Teshima, T., Shimoda, K., Akashi, K. & Harada, M., 7 1 2007, : : European Journal of Haematology. 79, 1, p. 17-24 8 p.

研究成果: ジャーナルへの寄稿記事

Acute Myeloid Leukemia
Down-Regulation
Mutation
Blood Cell Count
nucleophosmin
63 引用 (Scopus)

Hematopoietic developmental pathways: On cellular basis

Iwasaki, H. & Akashi, K., 10 15 2007, : : Oncogene. 26, 47, p. 6687-6696 10 p.

研究成果: ジャーナルへの寄稿評論記事

Hematopoietic Stem Cells
Stem Cells
Phenotype
Hematopoiesis
Transplantation
152 引用 (Scopus)

Immunology: Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF

Maeda, T., Merghoyb, T., Hobbs, R. M., Dong, L., Maeda, M., Zakrzewski, J., Van Den Brink, M. R. M., Zelent, A., Shigematsu, H., Akashi, K., Teruya-Feldstein, J., Cattoretti, G. & Pandolfi, P. P., 5 11 2007, : : Science. 316, 5826, p. 860-866 7 p.

研究成果: ジャーナルへの寄稿記事

Proto-Oncogenes
Allergy and Immunology
Notch Receptors
T-Lymphocytes
Hematopoietic Stem Cells
4 引用 (Scopus)

In vivo repopulation of cytoplasmically gene transferred hematopoietic cells by temperature-sensitive mutant of recombinant Sendai viral vector

Yoshida, K., Yonemitsu, Y., Tanaka, S., Yoshida, S., Shibata, S., Kondo, H., Okano, S., Ishikawa, F., Akashi, K., Inoue, M., Hasegawa, M. & Sueishi, K., 9 28 2007, : : Biochemical and Biophysical Research Communications. 361, 3, p. 811-816 6 p.

研究成果: ジャーナルへの寄稿記事

Bone Marrow Cells
Genes
Hematopoietic Stem Cells
Temperature
Gene transfer
240 引用 (Scopus)

Myeloid Lineage Commitment from the Hematopoietic Stem Cell

Iwasaki, H. & Akashi, K., 6 22 2007, : : Immunity. 26, 6, p. 726-740 15 p.

研究成果: ジャーナルへの寄稿評論記事

Hematopoietic Stem Cells
Blood Cells
Transcription Factors
Population
47 引用 (Scopus)

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Raffel, G. D., Mercher, T., Shigematsu, H., Williams, I. R., Cullen, D. E., Akashi, K., Bernard, O. A. & Gilliland, D. G., 4 3 2007, : : Proceedings of the National Academy of Sciences of the United States of America. 104, 14, p. 6001-6006 6 p.

研究成果: ジャーナルへの寄稿記事

Megakaryocytes
Leukemia, Megakaryoblastic, Acute
Lymphopoiesis
Mentha
Aptitude
203 引用 (Scopus)

Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myeloerythroid and Myelolymphoid Lineages

Arinobu, Y., Mizuno, S. I., Chong, Y., Shigematsu, H., Iino, T., Iwasaki, H., Graf, T., Mayfield, R., Chan, S., Kastner, P. & Akashi, K., 10 11 2007, : : Cell stem cell. 1, 4, p. 416-427 12 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Cytidine Monophosphate
Lymphoid Progenitor Cells
Lymphocytes
Population
73 引用 (Scopus)

The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways

Ishikawa, F., Niiro, H., Iino, T., Yoshida, S., Saito, N., Onohara, S., Miyamoto, T., Minagawa, H., Fujii, S. I., Shultz, L. D., Harada, M. & Akashi, K., 11 15 2007, : : Blood. 110, 10, p. 3591-3600 10 p.

研究成果: ジャーナルへの寄稿記事

Dendritic Cells
Genes
Lymphoid Progenitor Cells
Myeloid Progenitor Cells
Assays
188 引用 (Scopus)

The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation

Feinberg, M. W., Wara, A. K., Cao, Z., Lebedeva, M. A., Rosenbauer, F., Iwasaki, H., Hirai, H., Katz, J. P., Haspel, R. L., Gray, S., Akashi, K., Segre, J., Kaestner, K. H., Tenen, D. G. & Jain, M. K., 9 19 2007, : : EMBO Journal. 26, 18, p. 4138-4148 11 p.

研究成果: ジャーナルへの寄稿記事

Kruppel-Like Transcription Factors
T-cells
Phorbol Esters
Stem cells
Liver

The mechanisms of eosinophil lineage commitment

Mori, Y., Iwasaki, H. & Akashi, K., 5 2007, : : Biotherapy. 21, 3, p. 181-186 6 p.

研究成果: ジャーナルへの寄稿記事

Eosinophils
Granulocyte Precursor Cells
Monocytes
GATA Transcription Factors
Hypereosinophilic Syndrome
2006
228 引用 (Scopus)

C/EBPβ is required for 'emergency' granulopoiesis

Hirai, H., Zhang, P., Dayaram, T., Hetherington, C. J., Mizuno, S. I., Imanishi, J., Akashi, K. & Tenen, D. G., 7 1 2006, : : Nature Immunology. 7, 7, p. 732-739 8 p.

研究成果: ジャーナルへの寄稿記事

Emergencies
Granulocyte Precursor Cells
Granulocytes
Cytokines
Mycoses
29 引用 (Scopus)

Essential role for cyclin D3 in granulocyte colony-stimulating factor-driven expansion of neutrophil granulocytes

Sicinska, E., Lee, Y. M., Gits, J., Shigematsu, H., Yu, Q., Rebel, V. I., Geng, Y., Marshall, C. J., Akashi, K., Dorfman, D. M., Touw, I. P. & Sicinski, P., 11 1 2006, : : Molecular and cellular biology. 26, 21, p. 8052-8060 9 p.

研究成果: ジャーナルへの寄稿記事

Cyclin D3
Granulocyte Colony-Stimulating Factor
Granulocytes
Neutrophils
Granulocyte Colony-Stimulating Factor Receptors
151 引用 (Scopus)

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

Rosenbauer, F., Owens, B. M., Yu, L., Tumang, J. R., Steidl, U., Kutok, J. L., Clayton, L. K., Wagner, K., Scheller, M., Iwasaki, H., Liu, C., Hackanson, B., Akashi, K., Leutz, A., Rothstein, T. L., Plass, C. & Tenen, D. G., 1 1 2006, : : Nature genetics. 38, 1, p. 27-37 11 p.

研究成果: ジャーナルへの寄稿記事

Regulator Genes
Lymphocytes
Transcription Factors
Growth
T-Lymphoid Precursor Cells
46 引用 (Scopus)

Oncogenic K-ras cooperates with PML-RARα to induce an acute promyelocytic leukemia-like disease

Chan, I. T., Kutok, J. L., Williams, I. R., Cohen, S., Moore, S., Shigematsu, H., Ley, T. J., Akashi, K., Le Beau, M. M. & Gary Gilliland, D., 9 1 2006, : : Blood. 108, 5, p. 1708-1715 8 p.

研究成果: ジャーナルへの寄稿記事

Acute Promyelocytic Leukemia
Ports and harbors
Tretinoin
Chromosome Aberrations
Liver
202 引用 (Scopus)

The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages

Iwasaki, H., Mizuno, S. I., Arinobu, Y., Ozawa, H., Mori, Y., Shigematsu, H., Takatsu, K., Tenen, D. G. & Akashi, K., 11 1 2006, : : Genes and Development. 20, 21, p. 3010-3021 12 p.

研究成果: ジャーナルへの寄稿記事

CCAAT-Enhancer-Binding Proteins
Granulocyte Precursor Cells
Transcription Factors
Monocytes
Basophils
1 引用 (Scopus)

Thymus Exclusivity: All the Right Conditions for T Cells

Iwasaki, H. & Akashi, K., 1 1 2006, : : Immunity. 25, 5, p. 697-700 4 p.

研究成果: ジャーナルへの寄稿小調査

Thymus Gland
Immunity
Transcription Factors
T-Lymphocytes

Thymus Exclusivity: All the Right Conditions for T Cells (DOI:10.1016/j.immuni.2006.10.005)

Iwasaki, H. & Akashi, K., 12 1 2006, : : Immunity. 25, 6, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Thymus Gland
T-Lymphocytes
2005
88 引用 (Scopus)

Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease

Wang, J., Iwasaki, H., Krivtsov, A., Febbo, P. G., Thorner, A. R., Ernst, P., Anastasiadou, E., Kutok, J. L., Kogan, S. C., Zinkel, S. S., Fisher, J. K., Hess, J. L., Golub, T. R., Armstrong, S. A., Akashi, K. & Korsmeyer, S. J., 1 26 2005, : : EMBO Journal. 24, 2, p. 368-381 14 p.

研究成果: ジャーナルへの寄稿記事

Granulocyte-Macrophage Progenitor Cells
Macrophages
Leukemia
Fusion reactions
Genes
214 引用 (Scopus)

Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis

Arinobu, Y., Iwasaki, H., Gurish, M. F., Mizuno, S. I., Shigematsu, H., Ozawa, H., Tenen, D. G., Austen, K. F. & Akashi, K., 12 13 2005, : : Proceedings of the National Academy of Sciences of the United States of America. 102, 50, p. 18105-18110 6 p.

研究成果: ジャーナルへの寄稿記事

Basophils
Hematopoiesis
Cell Lineage
Mast Cells
CCAAT-Enhancer-Binding Proteins
580 引用 (Scopus)

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice

Ishikawa, F., Yasukawa, M., Lyons, B., Yoshida, S., Miyamoto, T., Yoshimoto, G., Watanabe, T., Akashi, K., Shultz, L. D. & Harada, M., 9 1 2005, : : Blood. 106, 5, p. 1565-1573 9 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-2 Receptors
Immune system
Human Development
Immune System
Blood
255 引用 (Scopus)

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

Iwasaki, H., Somoza, C., Shigematsu, H., Duprez, E. A., Iwasaki-Arai, J., Mizuno, S. I., Arinobu, Y., Geary, K., Zhang, P., Dayaram, T., Fenyus, M. L., Elf, S., Chan, S., Kastner, P., Huettner, C. S., Murray, R., Tenen, D. G. & Akashi, K., 9 1 2005, : : Blood. 106, 5, p. 1590-1600 11 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Stem cells
Cell Differentiation
Maintenance
B-Lymphocytes
22 引用 (Scopus)

Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/β2-microglobulinnull mice

Kawano, N., Ishikawa, F., Shimoda, K., Yasukawa, M., Nagafuji, K., Miyamoto, T., Baba, E., Tanaka, T., Yamasaki, S., Gondo, H., Otsuka, T., Ohshima, K., Shultz, L. D., Akashi, K. & Harada, M., 1 1 2005, : : Leukemia. 19, 8, p. 1384-1390 7 p.

研究成果: ジャーナルへの寄稿記事

Wiskott-Aldrich Syndrome
Severe Combined Immunodeficiency
Adult T Cell Leukemia Lymphoma
Newborn Infant
Human T-lymphotropic virus 1
130 引用 (Scopus)

Identification of eosinophil lineage-committed progenitors in the murine bone marrow

Iwasaki, H., Mizuno, S. I., Mayfield, R., Shigematsu, H., Arinobu, Y., Seed, B., Gurish, M. F., Takatsu, K. & Akashi, K., 6 20 2005, : : Journal of Experimental Medicine. 201, 12, p. 1891-1897 7 p.

研究成果: ジャーナルへの寄稿記事

Eosinophils
Bone Marrow
Monocytes
Granulocyte Precursor Cells
Mast Cells
141 引用 (Scopus)

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis

Koschmieder, S., Göttgens, B., Zhang, P., Iwasaki-Arai, J., Akashi, K., Kutok, J. L., Dayaram, T., Geary, K., Green, A. R., Tenen, D. G. & Huettner, C. S., 1 1 2005, : : Blood. 105, 1, p. 324-334 11 p.

研究成果: ジャーナルへの寄稿記事

Leukemia, Myeloid, Chronic Phase
Hematopoietic Stem Cells
Stem cells
Bone
Stem Cells
29 引用 (Scopus)

Lineage promiscuity and plasticity in hematopoietic development

Akashi, K., 1 1 2005, : : Annals of the New York Academy of Sciences. 1044, p. 125-131 7 p.

研究成果: ジャーナルへの寄稿記事

Plasticity
Transcription Factors
Lymphoid Progenitor Cells
Multipotent Stem Cells
Myeloid Progenitor Cells
21 引用 (Scopus)

Lineage promiscuous expression of transcription factors in normal hematopoiesis

Miyamoto, T. & Akashi, K., 6 1 2005, : : International journal of hematology. 81, 5, p. 361-367 7 p.

研究成果: ジャーナルへの寄稿評論記事

Hematopoiesis
Hematopoietic Stem Cells
Transcription Factors
Lymphoid Progenitor Cells
Myeloid Progenitor Cells
305 引用 (Scopus)

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype

Growney, J. D., Shigematsu, H., Li, Z., Lee, B. H., Adelsperger, J., Rowan, R., Curley, D. P., Kutok, J. L., Akashi, K., Williams, I. R., Speck, N. A. & Gilliland, D. G., 7 15 2005, : : Blood. 106, 2, p. 494-504 11 p.

研究成果: ジャーナルへの寄稿記事

Hematopoiesis
Core Binding Factor Alpha 2 Subunit
Genes
Phenotype
T-cells

Mcl-1, which can prevent leukemia cell death, is necessary for bone marrow stem cell survival

Iwasaki, H., Ong, C. C., Suh, H., Mizuno, S., Akashi, K. & Korsmeyer, S. J., 3 1 2005, : : Cancer Biology and Therapy. 4, 3

研究成果: ジャーナルへの寄稿コメント/討論

390 引用 (Scopus)

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells

Opferman, J. T., Iwasaki, H., Ong, C. C., Suh, H., Mizuno, S. I., Akashi, K. & Korsmeyer, S. J., 2 18 2005, : : Science. 307, 5712, p. 1101-1104 4 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Bone Marrow
Intercellular Signaling Peptides and Proteins
Homeostasis
Stem Cell Factor
120 引用 (Scopus)

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element

Okuno, Y., Huang, G., Rosenbauer, F., Evans, E. K., Radomska, H. S., Iwasaki, H., Akashi, K., Moreau-Gachelin, F., Li, Y., Zhang, P., Göttgens, B. & Tenen, D. G., 4 1 2005, : : Molecular and cellular biology. 25, 7, p. 2832-2845 14 p.

研究成果: ジャーナルへの寄稿記事

Reporter Genes
Homeostasis
Spleen Focus-Forming Viruses
Friend murine leukemia virus
Gene Expression
194 引用 (Scopus)

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations

Mohi, M. G., Williams, I. R., Dearolf, C. R., Chan, G., Kutok, J. L., Cohen, S., Morgan, K., Boulton, C., Shigematsu, H., Keilhack, H., Akashi, K., Gilliland, D. G. & Neel, B. G., 2 2005, : : Cancer Cell. 7, 2, p. 179-191 13 p.

研究成果: ジャーナルへの寄稿記事

Juvenile Myelomonocytic Leukemia
Leukemia
Noonan Syndrome
Mutation
Germ-Line Mutation
19 引用 (Scopus)

TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common β chain of cytokine receptors

Inukai, T., Inaba, T., Dang, J., Kuribara, R., Ozawa, K., Miyajima, A., Wu, W., Look, A. T., Arinobu, Y., Iwasaki, H., Akashi, K., Kagami, K., Goi, K., Sugita, K. & Nakazawa, S., 6 1 2005, : : Blood. 105, 11, p. 4437-4444 8 p.

研究成果: ジャーナルへの寄稿記事

Basic-Leucine Zipper Transcription Factors
Thyrotrophs
Cytokine Receptors
Cell growth
Leukemia
27 引用 (Scopus)

The complex cartography of stem cell commitment

Akashi, K., Traver, D. & Zon, L. I., 4 22 2005, : : Cell. 121, 2, p. 160-162 3 p.

研究成果: ジャーナルへの寄稿小調査

Hematopoietic Stem Cells
Stem cells
Stem Cells
Multipotent Stem Cells
Megakaryocytes
2004
375 引用 (Scopus)

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1

Rosenbauer, F., Wagner, K., Kutok, J. L., Iwasaki, H., Le Beau, M. M., Okuno, Y., Akashi, K., Fiering, S. & Tenen, D. G., 6 1 2004, : : Nature genetics. 36, 6, p. 624-630 7 p.

研究成果: ジャーナルへの寄稿記事

Acute Myeloid Leukemia
Transcription Factors
Gene Knockout Techniques
Hematopoiesis
Granulocyte Colony-Stimulating Factor
1 引用 (Scopus)

Common Myeloid Progenitors

Traver, D. & Akashi, K., 9 14 2004, Adult and Fetal. Elsevier Inc., 巻 2. p. 355-376 22 p.

研究成果: 著書/レポートタイプへの貢献

Myeloid Progenitor Cells
Hematopoietic Stem Cells
Stem cells
Cytology
Stem Cells
219 引用 (Scopus)

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

Chan, I. T., Kutok, J. L., Williams, I. R., Cohen, S., Kelly, L., Shigematsu, H., Johnson, L., Akashi, K., Tuveson, D. A., Jacks, T. & Gilliland, D. G., 2 2004, : : Journal of Clinical Investigation. 113, 4, p. 528-538 11 p.

研究成果: ジャーナルへの寄稿記事

Acute Myeloid Leukemia
Alleles
Mutation
Extramedullary Hematopoiesis
Hematopoietic System