• 4095 引用
  • 36 h指数
1993 …2020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 4095 引用
  • 36 h指数
  • 76 記事
  • 7 評論記事
  • 1
フィルター
記事
2020

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity

Fujiyama, H., Tsuji, T., Hironaka, K., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2020, : : Journal of biochemistry. 167, 1, p. 15-24 10 p.

研究成果: ジャーナルへの寄稿記事

2019

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

Yokoyama, T., Yukuhiro, M., Iwasaki, Y., Tanaka, C., Sankoda, K., Fujiwara, R., Shibuta, A., Higashi, T., Motoyama, K., Arima, H., Yoshida, K., Sugimoto, N., Morimoto, H., Kosako, H., Ohshima, T. & Fujita, M., 12 1 2019, : : Scientific reports. 9, 1, 16825.

研究成果: ジャーナルへの寄稿記事

公開

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib

Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, M. T. & Fujita, M., 3 2019, : : Cancer Science. 110, 3, p. 1044-1053 10 p.

研究成果: ジャーナルへの寄稿記事

公開
3 引用 (Scopus)
2018
15 引用 (Scopus)

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 7 27 2018, : : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

研究成果: ジャーナルへの寄稿記事

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of cell science. 131, 15

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Sensitive detection of fluorescence in western blotting by merging images

Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 2018, : : PloS one. 13, 1, e0191532.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)
2017

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2017, : : EMBO Reports. 18, 1, p. 123-137 15 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes

Yoshimatsu, Y., Nakahara, T., Tanaka, K., Inagawa, Y., Narisawa-Saito, M., Yugawa, T., Ohno, S. I., Fujita, M., Nakagama, H. & Kiyono, T., 7 2017, : : Cancer Science. 108, 7, p. 1303-1309 7 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

TRF2 recruits ORC through TRFH domain dimerization

Higa, M., Kushiyama, T., Kurashige, S., Kohmon, D., Enokitani, K., Iwahori, S., Sugimoto, N., Yoshida, K. & Fujita, M., 1 1 2017, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 1, p. 191-201 11 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)
2016

Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas

Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., 10 2016, : : PloS one. 11, 10, e0165473.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Nucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formation

Aizawa, M., Sugimoto, N., Watanabe, S., Yoshida, K. & Fujita, M., 11 1 2016, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 11, p. 2739-2748 10 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)
2015

A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo

Ohira, M., Iwasaki, Y., Tanaka, C., Kuroki, M., Matsuo, N., Kitamura, T., Yukuhiro, M., Morimoto, H., Pang, N., Liu, B., Kiyono, T., Amemiya, M., Tanaka, K., Yoshida, K., Sugimoto, N., Ohshima, T. & Fujita, M., 5 19 2015, : : Biochimica et Biophysica Acta - General Subjects. 1850, 9, p. 1676-1684 9 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

Sugimoto, N., Maehara, K., Yoshida, K., Yasukouchi, S., Osano, S., Watanabe, S., Aizawa, M., Yugawa, T., Kiyono, T., Kurumizaka, H., Ohkawa, Y. & Fujita, M., 1 1 2015, : : Nucleic acids research. 43, 12, p. 5898-5911 14 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)
2014

ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication

Iwahori, S., Kohmon, D., Kobayashi, J., Tani, Y., Yugawa, T., Komatsu, K., Kiyono, T., Sugimoto, N. & Fujita, M., 2 1 2014, : : Cell Cycle. 13, 3, p. 471-481 11 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Generation of a monoclonal antibody for INI1/hSNF5/BAF47

Harada, A., Hayashi, M., Kuniyoshi, Y., Semba, Y., Sugahara, S., Tachibana, T., Ohkawa, Y. & Fujita, M., 2 1 2014, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 1, p. 49-51 3 p.

研究成果: ジャーナルへの寄稿記事

2013

Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation

Yugawa, T., Nishino, K., Ohno, S. I., Nakahara, T., Fujita, M., Goshima, N., Umezawa, A. & Kiyono, T., 11 15 2013, : : Molecular and cellular biology. 33, 22, p. 4434-4447 14 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)
2012

A critical role of MYC for transformation of human cells by HPV16 E6E7 and oncogenic HRAS

Narisawa-Saito, M., Inagawa, Y., Yoshimatsu, Y., Haga, K., Tanaka, K., Egawa, N., Ohno, S. I., Ichikawa, H., Yugawa, T., Fujita, M. & Kiyono, T., 4 16 2012, : : Carcinogenesis. 33, 4, p. 910-917 8 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex

Nishimoto, N., Watanabe, M., Watanabe, S., Sugimoto, N., Yugawa, T., Ikura, T., Koiwai, O., Kiyono, T. & Fujita, M., 8 15 2012, : : Journal of Cell Science. 125, 16, p. 3870-3882 13 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

The E1 Protein of Human Papillomavirus Type 16 Is Dispensable for Maintenance Replication of the Viral Genome

Egawa, N., Nakahara, T., Ohno, S. I., Narisawa-Saito, M., Yugawa, T., Fujita, M., Yamato, K., Natori, Y. & Kiyono, T., 3 1 2012, : : Journal of virology. 86, 6, p. 3276-3283 8 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)
2011
27 引用 (Scopus)
2010

CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells

Yoshida, K., Sugimoto, N., Iwahori, S., Yugawa, T., Narisawa-Saito, M., Kiyono, T. & Fujita, M., 1 15 2010, : : Journal of cell science. 123, 2, p. 225-235 11 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

ΔNp63α repression of the Notch1 gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells

Yugawa, T., Narisawa-Saito, M., Yoshimatsu, Y., Haga, K., Ohno, S. I., Egawa, N., Fujita, M. & Kiyono, T., 5 15 2010, : : Cancer Research. 70, 10, p. 4034-4044 11 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)
2009

Histone acetyltransferase Hbo1: Catalytic activity, cellular abundance, and links to primary cancers

Iizuka, M., Takahashi, Y., Mizzen, C. A., Cook, R. G., Fujita, M., Allis, C. D., Frierson, H. F., Fukusato, T. & Smith, M. M., 5 1 2009, : : Gene. 436, 1-2, p. 108-114 7 p.

研究成果: ジャーナルへの寄稿記事

58 引用 (Scopus)

Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes

Sasaki, R., Narisawa-Saito, M., Yugawa, T., Fujita, M., Tashiro, H., Katabuchi, H. & Kiyono, T., 1 1 2009, : : Carcinogenesis. 30, 3, p. 423-431 9 p.

研究成果: ジャーナルへの寄稿記事

69 引用 (Scopus)

Redundant and differential regulation of multiple licensing factors ensures prevention of re-replication in normal human cells

Sugimoto, N., Yoshida, K., Tatsumi, Y., Yugawa, T., Narisawa-Saito, M., Waga, S., Kiyono, T. & Fujita, M., 4 15 2009, : : Journal of cell science. 122, 8, p. 1184-1191 8 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)
2008

An in vitro multistep carcinogenesis model for human cervical cancer

Narisawa-Saito, M., Yoshimatsu, Y., Ohno, S. I., Yugawa, T., Egawa, N., Fujita, M., Hirohashi, S. & Kiyono, T., 7 15 2008, : : Cancer Research. 68, 14, p. 5699-5705 7 p.

研究成果: ジャーナルへの寄稿記事

46 引用 (Scopus)

Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction

Mizushina, Y., Takeuchi, T., Takakusagi, Y., Yonezawa, Y., Mizuno, T., Yanagi, K. I., Imamoto, N., Sugawara, F., Sakaguchi, K., Yoshida, H. & Fujita, M., 2 1 2008, : : Biochimica et Biophysica Acta - General Subjects. 1780, 2, p. 203-213 11 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Identification of novel human Cdt1-binding proteins by a proteomics approach: Proteolytic regulation by APC/CCdh1

Sugimoto, N., Kitabayashi, I., Osano, S., Tatsumi, Y., Yugawa, T., Narisawa-Saito, M., Matsukage, A., Kiyono, T. & Fujita, M., 3 1 2008, : : Molecular biology of the cell. 19, 3, p. 1007-1021 15 p.

研究成果: ジャーナルへの寄稿記事

46 引用 (Scopus)

Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction

Mizushina, Y., Takeuchi, T., Takakusagi, Y., Sugawara, F., Sakaguchi, K., Yoshida, H. & Fujita, M., 3 2008, : : International Journal of Molecular Medicine. 21, 3, p. 281-290 10 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres

Tatsumi, Y., Ezura, K., Yoshida, K., Yugawa, T., Narisawa-Saito, M., Kiyono, T., Ohta, S., Obuse, C. & Fujita, M., 12 1 2008, : : Genes to Cells. 13, 10, p. 1045-1059 15 p.

研究成果: ジャーナルへの寄稿記事

34 引用 (Scopus)

The inhibitory action of SQDG (sulfoquinovosyl diacylglycerol) from spinach on Cdt1-geminin interaction

Mizushina, Y., Takeuchi, T., Hada, T., Maeda, N., Sugawara, F., Yoshida, H. & Fujita, M., 6 1 2008, : : Biochimie. 90, 6, p. 947-956 10 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)
2007

E6AP-dependent degradation of DLG4/PSD95 by high-risk human papillomavirus type 18 E6 protein

Handa, K., Yugawa, T., Narisawa-Saito, M., Ohno, S. I., Fujita, M. & Kiyono, T., 2 1 2007, : : Journal of virology. 81, 3, p. 1379-1389 11 p.

研究成果: ジャーナルへの寄稿記事

51 引用 (Scopus)

Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT

Haga, K., Ohno, S. I., Yugawa, T., Narisawa-Saito, M., Fujita, M., Sakamoto, M., Galloway, D. A. & Kiyono, T., 2 1 2007, : : Cancer Science. 98, 2, p. 147-154 8 p.

研究成果: ジャーナルへの寄稿記事

75 引用 (Scopus)

HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes

Narisawa-Saito, M., Handa, K., Yugawa, T., Ohno, S., Fujita, M. & Kiyono, T., 3 10 2007, : : Oncogene. 26, 21, p. 2988-2996 9 p.

研究成果: ジャーナルへの寄稿記事

37 引用 (Scopus)

Regulation of Notch1 gene expression by p53 in epithelial cells

Yugawa, T., Handa, K., Narisawa-Saito, M., Ohno, S. I., Fujita, M. & Kiyono, T., 5 1 2007, : : Molecular and cellular biology. 27, 10, p. 3732-3742 11 p.

研究成果: ジャーナルへの寄稿記事

127 引用 (Scopus)
2006

Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability

Tatsumi, Y., Sugimoto, N., Yugawa, T., Narisawa-Saito, M., Kiyono, T. & Fujita, M., 8 1 2006, : : Journal of cell science. 119, 15, p. 3128-3140 13 p.

研究成果: ジャーナルへの寄稿記事

85 引用 (Scopus)

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis

Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K. I., Nakayama, K., Fujita, M., Lygerou, Z. & Nishimoto, T., 3 8 2006, : : EMBO Journal. 25, 5, p. 1126-1136 11 p.

研究成果: ジャーナルへの寄稿記事

280 引用 (Scopus)
2005

Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection

Shirata, N., Kudoh, A., Daikoku, T., Tatsumi, Y., Fujita, M., Kiyono, T., Sugaya, Y., Isomura, H., Ishizaki, K. & Tsurumi, T., 8 26 2005, : : Journal of Biological Chemistry. 280, 34, p. 30336-30341 6 p.

研究成果: ジャーナルへの寄稿記事

103 引用 (Scopus)

Architecture of replication compartments formed during Epstein-Barr virus lytic replication

Daikoku, T., Kudoh, A., Fujita, M., Sugaya, Y., Isomura, H., Shirata, N. & Tsurumi, T., 3 2005, : : Journal of virology. 79, 6, p. 3409-3418 10 p.

研究成果: ジャーナルへの寄稿記事

66 引用 (Scopus)

Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment

Kudoh, A., Fujita, M., Zhang, L., Shirata, N., Daikoku, T., Sugaya, Y., Isomura, H., Nishiyama, Y. & Tsurumi, T., 3 4 2005, : : Journal of Biological Chemistry. 280, 9, p. 8156-8163 8 p.

研究成果: ジャーナルへの寄稿記事

137 引用 (Scopus)
2004

Cdt1 Phosphorylation by Cyclin A-dependent Kinases Negatively Regulates Its Function without Affecting Geminin Binding

Sugimoto, N., Tatsumi, Y., Tsurumi, T., Matsukage, A., Kiyono, T., Nishitani, H. & Fujita, M., 5 7 2004, : : Journal of Biological Chemistry. 279, 19, p. 19691-19697 7 p.

研究成果: ジャーナルへの寄稿記事

148 引用 (Scopus)

Inhibition of S-Phase Cyclin-Dependent Kinase Activity Blocks Expression of Epstein-Barr Virus Immediate-Early and Early Genes, Preventing Viral Lytic Replication

Kudoh, A., Daikoku, T., Sugaya, Y., Isomura, H., Fujita, M., Kiyono, T., Nishiyama, Y. & Tsurumi, T., 1 2004, : : Journal of virology. 78, 1, p. 104-115 12 p.

研究成果: ジャーナルへの寄稿記事

59 引用 (Scopus)

In vivo dynamics of EBNA1-oriP interaction during latent and lytic replication of Epstein-Barr virus

Daikoku, T., Kudoh, A., Fujita, M., Sugaya, Y., Isomura, H. & Tsurumi, T., 12 24 2004, : : Journal of Biological Chemistry. 279, 52, p. 54817-54825 9 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)
2003

Establishment of latrunculin-A resistance in HeLa cells by expression of R183A D184A mutant β-actin

Fujita, M., Ichinose, S., Kiyono, T., Tsurumi, T. & Omori, A., 1 30 2003, : : Oncogene. 22, 4, p. 627-631 5 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Reactivation of lytic replication from B cells latently infected with Epstein-Barr virus occurs with high S-phase cyclin-dependent kinase activity while inhibiting cellular DNA replication

Kudoh, A., Fujita, M., Kiyono, T., Kuzushima, K., Sugaya, Y., Izuta, S., Nishiyama, Y. & Tsurumi, T., 1 2003, : : Journal of virology. 77, 2, p. 851-861 11 p.

研究成果: ジャーナルへの寄稿記事

78 引用 (Scopus)

The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle

Ohta, S., Tatsumi, Y., Fujita, M., Tsurimoto, T. & Obuse, C., 10 17 2003, : : Journal of Biological Chemistry. 278, 42, p. 41535-41540 6 p.

研究成果: ジャーナルへの寄稿記事

59 引用 (Scopus)
2002

Nuclear organization of DNA replication initiation proteins in mammalian cells

Fujita, M., Ishimi, Y., Nakamura, H., Kiyono, T. & Tsurumi, T., 3 22 2002, : : Journal of Biological Chemistry. 277, 12, p. 10354-10361 8 p.

研究成果: ジャーナルへの寄稿記事

65 引用 (Scopus)
2000

Cdk2-dependent and -independent pathways in E2F-mediated S phase induction

Arata, Y., Fujita, M., Ohtani, K., Kijima, S. & Kato, J. Y., 3 3 2000, : : Journal of Biological Chemistry. 275, 9, p. 6337-6345 9 p.

研究成果: ジャーナルへの寄稿記事

69 引用 (Scopus)

Co-expression of human chaperone Hsp70 and Hsdj or Hsp40 co-factor increases solubility of overexpressed target proteins in insect cells

Yokoyama, N., Hirata, M., Ohtsuka, K., Nishiyama, Y., Fujii, K., Fujita, M., Kuzushima, K., Kiyono, T. & Tsurumi, T., 9 7 2000, : : Biochimica et Biophysica Acta - Gene Structure and Expression. 1493, 1-2, p. 119-124 6 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)