Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1998 2019

  • 2106 引用
  • 26 h指数
  • 47 記事
  • 4 評論記事
  • 1 レター
2019

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Takaki-Kuwahara, A., Arinobu, Y., Miyawaki, K., Yamada, H., Tsuzuki, H., Irino, K., Ayano, M., kimoto, Y., Mitoma, H., Akahoshi, M., Tsukamoto, H., Horiuchi, T., Niiro, H. & Akashi, K., 8 30 2019, : : Arthritis Research and Therapy. 21, 1, 198.

研究成果: ジャーナルへの寄稿記事

公開
Rheumatoid Arthritis
Joints
Lymphocytes
Cytokines
Synovial Fluid
Phase II Clinical Trials
Clinical Trials, Phase I
Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Japan
2018
5 引用 (Scopus)
glycohemoglobin
rheumatoid arthritis
tumor necrosis factors
Glycosylated Hemoglobin A
observational studies
2017
3 引用 (Scopus)

A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study

Nakagawa, J., Koyama, Y., Kawakami, A., Ueki, Y., Tsukamoto, H., Horiuchi, T., Nagano, S., Uchino, A., Ota, T., Akahoshi, M. & Akashi, K., 8 11 2017, : : Arthritis research & therapy. 19, 1, 1 p.

研究成果: ジャーナルへの寄稿記事

Multicenter Studies
Observational Studies
Interleukin-6
Rheumatoid Arthritis
Tumor Necrosis Factor-alpha
9 引用 (Scopus)

Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes

Tsuzuki, H., Arinobu, Y., Miyawaki, K., Takaki, A., Ota, S. I., Ota, Y., Mitoma, H., Akahoshi, M., Mori, Y., Iwasaki, H., Niiro, H., Tsukamoto, H. & Akashi, K., 1 1 2017, : : Immunology. 150, 1, p. 64-73 10 p.

研究成果: ジャーナルへの寄稿記事

Granulocytes
Hypersensitivity
Eosinophils
Basophils
Mast Cells
4 引用 (Scopus)

Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

Sakamoto, Y., Yamamoto, T., Sugano, N., Takahashi, D., Watanabe, T., Atsumi, T., Nakamura, J., Hasegawa, Y., Akashi, K., Narita, I., Miyamoto, T., Takeuchi, T., Ikari, K., Amano, K., Fujie, A., Kubo, T., Tada, Y., Kaneuji, A., Nakamura, H., Miyamura, T. および70人, Kabata, T., Yamaji, K., Okawa, T., Sudo, A., Ohzono, K., Tanaka, Y., Yasunaga, Y., Matsuda, S., Imai, Y., Nakashima, Y., motomura, G., Ikemura, S., Yamaguchi, R., Karasuyama, K., Sonoda, K., Nishii, T., Sakai, T., Takao, M., Irie, T., Asano, T., Iwasaki, N., Atsumi, T., Tamaoki, S., Nakanishi, R., Tanabe, S., Kishida, S., Hagiwara, S., Seki, T., Tsukamoto, H., Niiro, H., Arinobu, Y., Akahoshi, M., Mitoma, H., Ayano, M., Kuroda, T., Toyama, Y., Funayama, A., Hanaoka, H., Yamaoka, K., Kawaguchi, Y., Yamanaka, H., Hosozawa, T., Momohara, S., Chino, K., Fujioka, M., Ueshima, K., Ishida, M., Saito, M., Hayashi, S., Ikegami, A., Ichiseki, T., Mizokawa, S., Ohta, Y., Kajino, Y., Sekiya, F., Higuchi, F., Hasegawa, M., Miyamoto, N., Miyazaki, S., Yamaguchi, T., Ando, W., Saito, K., Nakano, K., Kuroda, Y., Yamasaki, T., Akiyama, M., Kubo, M., Kamatani, Y., Iwamoto, Y. & Ikegawa, S., 12 1 2017, : : Scientific reports. 7, 1, 15035.

研究成果: ジャーナルへの寄稿記事

Osteonecrosis
Genome-Wide Association Study
Thigh
Hip Joint
Drinking
2016
9 引用 (Scopus)

Generation mechanism of RANKL + effector memory B cells: Relevance to the pathogenesis of rheumatoid arthritis

Ota, Y., Niiro, H., Ota, S. I., Ueki, N., Tsuzuki, H., Nakayama, T., Mishima, K., Higashioka, K., Jabbarzadeh-Tabrizi, S., Mitoma, H., Akahoshi, M., Arinobu, Y., Kukita, A., Yamada, H., Tsukamoto, H. & Akashi, K., 3 16 2016, : : Arthritis Research and Therapy. 18, 1, 67.

研究成果: ジャーナルへの寄稿記事

B-Lymphocyte Subsets
Rheumatoid Arthritis
B-Lymphocytes
Interferons
Osteoprotegerin
2015
12 引用 (Scopus)
Systemic Scleroderma
Endothelial Cells
Cytokines
T-Lymphocytes
Wounds and Injuries
6 引用 (Scopus)
Dermatomyositis
Interstitial Lung Diseases
Serum
Polymyositis
Protein S
2014
4 引用 (Scopus)

[A case report of malignant lymphoma receiving infliximab therapy with Behçet's disease].

Sonoda, K., Fukuhara, T., Yoshikawa, H., Takeda, A., Yoshimura, T., Akahoshi, M., Kusumoto, H., Kohno, K., Kato, K., Akashi, K., Kouhashi, K., Aijima, S., Namba, K. & Ishibashi, T., 1 1 2014, : : Nippon Ganka Gakkai zasshi. 118, 5, p. 440-445 6 p.

研究成果: ジャーナルへの寄稿記事

Lymphoma
Cyclosporine
Therapeutics
Drug Therapy
Lymphoma, Large B-Cell, Diffuse
2013
Collagen Diseases
Autoimmune Hepatitis
Connective Tissue Diseases
Biliary Liver Cirrhosis
Gastrointestinal Diseases
2011
78 引用 (Scopus)

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

Akahoshi, M., Song, C. H., Piliponsky, A. M., Metz, M., Guzzetta, A., Åbrink, M., Schlenner, S. M., Feyerabend, T. B., Rodewald, H. R., Pejler, G., Tsai, M. & Galli, S. J., 10 3 2011, : : Journal of Clinical Investigation. 121, 10, p. 4180-4191 12 p.

研究成果: ジャーナルへの寄稿記事

Scorpion Venoms
Chymases
Lizards
Vasoactive Intestinal Peptide
Venoms
55 引用 (Scopus)

Th subset balance in lupus nephritis

Miyake, K., Akahoshi, M. & Nakashima, H., 11 24 2011, : : Journal of Biomedicine and Biotechnology. 2011, 980286.

研究成果: ジャーナルへの寄稿評論記事

Lupus Nephritis
Cytokines
T-cells
Lymphocytes
Interleukin-17
2008
13 引用 (Scopus)

Acquired hemophilia in a patient with systemic lupus erythematosus: A case report and literature review

Akahoshi, M., Aizawa, K., Nagano, S., Inoue, H., Sadanaga, A., Arinobu, Y., Niiro, H. & Nakashima, H., 6 13 2008, : : Modern Rheumatology. 18, 5, p. 511-515 5 p.

研究成果: ジャーナルへの寄稿記事

Factor VIII
Hemophilia A
Systemic Lupus Erythematosus
Ecchymosis
Partial Thromboplastin Time
41 引用 (Scopus)

Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor α(WSX-1)

Sugiyama, N., Nakashima, H., Yoshimura, T., Sadanaga, A., Shimizu, S., Masutani, K., Igawa, T., Akahoshi, M., Miyake, K., Takeda, A., Yoshimura, A., Hamano, S. & Yoshida, H., 10 1 2008, : : Annals of the Rheumatic Diseases. 67, 10, p. 1461-1467 7 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-27
Inbred MRL lpr Mouse
Interleukin Receptors
Transgenic Mice
Phenotype
19 引用 (Scopus)

Mutation screening of the CARD15 gene in sarcoidosis

Akahoshi, M., Ishihara, M., Namba, K., Kitaichi, N., Ando, Y., Takenaka, S., Ishida, T., Ohno, S., Mizuki, N., Nakashima, H. & Shirakawa, T., 6 1 2008, : : Tissue antigens. 71, 6, p. 564-567 4 p.

研究成果: ジャーナルへの寄稿記事

Sarcoidosis
Screening
Genes
Mutation
Pediatrics
35 引用 (Scopus)

Promoter polymorphisms in the IRF3 gene confer protection against systemic lupus erythematosus

Akahoshi, M., Nakashima, H., Sadanaga, A., Miyake, K., Obara, K., Tamari, M., Hirota, T., Matsuda, A. & Shirakawa, T., 7 15 2008, : : Lupus. 17, 6, p. 568-574 7 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
Single Nucleotide Polymorphism
Haplotypes
Genes
Interferon Type I
2007
86 引用 (Scopus)

Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice

Sadanaga, A., Nakashima, H., Akahoshi, M., Masutani, K., Miyake, K., Igawa, T., Sugiyama, N., Niiro, H. & Harada, M., 5 1 2007, : : Arthritis and rheumatism. 56, 5, p. 1618-1628 11 p.

研究成果: ジャーナルへの寄稿記事

Inbred MRL lpr Mouse
Nephritis
Knockout Mice
Toll-Like Receptor 3
Splenomegaly
2006
49 引用 (Scopus)

Association between ADAM33 polymorphisms and adult asthma in the Japanese population

Hirota, T., Hasegawa, K., Obara, K., Matsuda, A., Akahoshi, M., Nakashima, K., Shirakawa, T., Doi, S., Fujita, K., Suzuki, Y., Nakamura, Y. & Tamari, M., 7 1 2006, : : Clinical and Experimental Allergy. 36, 7, p. 884-891 8 p.

研究成果: ジャーナルへの寄稿記事

Single Nucleotide Polymorphism
Asthma
Haplotypes
Population
Disintegrins
16 引用 (Scopus)

Association of the RIP2 gene with childhood atopic asthma

Nakashima, K., Hirota, T., Suzuki, Y., Akahoshi, M., Shimizu, M., Jodo, A., Doi, S., Fujita, K., Ebisawa, M., Yoshihara, S., Enomoto, T., Shirakawa, T., Kishi, F., Nakamura, Y. & Tamari, M., 1 1 2006, : : Allergology International. 55, 1, p. 77-83 7 p.

研究成果: ジャーナルへの寄稿記事

Asthma
Genes
Haplotypes
Receptor-Interacting Protein Serine-Threonine Kinases
Chromosome Mapping
11 引用 (Scopus)

Roles of genetic variations in signalling/immunoregulatory molecules in susceptibility to systemic lupus erythematosus

Akahoshi, M., Nakashima, H. & Shirakawa, T., 8 1 2006, : : Seminars in Immunology. 18, 4, p. 224-229 6 p.

研究成果: ジャーナルへの寄稿評論記事

Systemic Lupus Erythematosus
Autoimmune Diseases
Genes
Chromosomes
Technology
27 引用 (Scopus)

Th1/Th2 balance of SLE patients with lupus nephritis.

Nakashima, H., Akahoshi, M. & Masutani, K., 1 1 2006, : : Rinsho byori. The Japanese journal of clinical pathology. 54, 7, p. 706-713 8 p.

研究成果: ジャーナルへの寄稿評論記事

Th1-Th2 Balance
Lupus Nephritis
Systemic Lupus Erythematosus
Cytokines
Nephritis
2005
5 引用 (Scopus)

Association between IFNA genotype and the risk of systemic lupus erythematosus

Nakashima, H., Matsuno, S., Akahoshi, M., Miyake, K., Inoue, Y., Tanaka, Y., Ninomiya, I., Shimizu, S., Igawa, T., Sadanaga, A., Otsuka, T. & Harada, M., 2 1 2005, : : Clinical Rheumatology. 24, 1, p. 38-40 3 p.

研究成果: ジャーナルへの寄稿記事

Systemic Lupus Erythematosus
Interferons
Genotype
Autoantigens
Antigen-Presenting Cells
38 引用 (Scopus)

Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes

Takahashi, N., Akahoshi, M., Matsuda, A., Ebe, K., Inomata, N., Obara, K., Hirota, T., Nakashima, K., Shimizu, M., Tamari, M., Doi, S., Miyatake, A., Enomoto, T., Nakashima, H., Ikezawa, Z. & Shirakawa, T., 11 1 2005, : : Human Molecular Genetics. 14, 21, p. 3149-3159 11 p.

研究成果: ジャーナルへの寄稿記事

Atopic Dermatitis
Immunoglobulin E
Phenotype
Interleukin-12
Cytokines
34 引用 (Scopus)

Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma

Matsuda, A., Hirota, T., Akahoshi, M., Shimizu, M., Tamari, M., Miyatake, A., Takahashi, A., Nakashima, K., Takahashi, N., Obara, K., Yuyama, N., Doi, S., Kamogawa, Y., Enomoto, T., Ohshima, K., Tsunoda, T., Miyatake, S., Fujita, K., Kusakabe, M., Izuhara, K. および3人, Nakamura, Y., Hopkin, J. & Shirakawa, T., 10 1 2005, : : Human Molecular Genetics. 14, 19, p. 2779-2786 8 p.

研究成果: ジャーナルへの寄稿記事

Tenascin
Single Nucleotide Polymorphism
Asthma
Elasticity
Alternative Splicing
47 引用 (Scopus)

Functional haplotypes of IL-12B are associated with childhood atopic asthma

Hirota, T., Suzuki, Y., Hasegawa, K., Obara, K., Matsuda, A., Akahoshi, M., Nakashima, K., Cheng, L., Takahashi, N., Shimizu, M., Doi, S., Fujita, K., Enomoto, T., Ebisawa, M., Yoshihara, S., Nakamura, Y., Kishi, F., Shirakawa, T. & Tamari, M., 10 1 2005, : : Journal of Allergy and Clinical Immunology. 116, 4, p. 789-795 7 p.

研究成果: ジャーナルへの寄稿記事

Haplotypes
Asthma
Linkage Disequilibrium
3' Untranslated Regions
Chromosome Mapping
67 引用 (Scopus)

Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma

Akahoshi, M., Obara, K., Hirota, T., Matsuda, A., Hasegawa, K., Takahashi, N., Shimizu, M., Nakashima, K., Cheng, L., Doi, S., Fujiwara, H., Miyatake, A., Fujita, K., Higashi, N., Taniguchi, M., Enomoto, T., Mao, X. Q., Nakashima, H., Adra, C. N., Nakamura, Y. および2人, Tamari, M. & Shirakawa, T., 6 1 2005, : : Human Genetics. 117, 1, p. 16-26 11 p.

研究成果: ジャーナルへの寄稿記事

Aspirin Induced Asthma
Asthma
Single Nucleotide Polymorphism
Genes
Phenotype
134 引用 (Scopus)

Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis

Shimizu, M., Matsuda, A., Yanagisawa, K., Hirota, T., Akahoshi, M., Inomata, N., Ebe, K., Tanaka, K., Sugiura, H., Nakashima, K., Tamari, M., Takahashi, N., Obara, K., Enomoto, T., Okayama, Y., Gao, P. S., Huang, S. K., Tominaga, S. I., Ikezawa, Z. & Shirakawa, T., 10 1 2005, : : Human Molecular Genetics. 14, 19, p. 2919-2927 9 p.

研究成果: ジャーナルへの寄稿記事

Atopic Dermatitis
Single Nucleotide Polymorphism
Genes
Th2 Cells
Alleles
9 引用 (Scopus)

Lack of association between the IL13 variant Arg110Gln and susceptibility to cedar pollinosis in a Japanese population

Cheng, L., Hirota, T., Enomoto, T., Tamari, M., Akahoshi, M., Matsuda, A., Shimizu, M., Takahashi, N., Enomoto, K., Yamasaki, A., Mao, X. Q., Hopkin, J. M. & Shirakawa, T., 12 1 2005, : : International Archives of Allergy and Immunology. 139, 1, p. 25-30 6 p.

研究成果: ジャーナルへの寄稿記事

Seasonal Allergic Rhinitis
Interleukin-13
Population
Gene Frequency
Healthy Volunteers
88 引用 (Scopus)

Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)

Shimizu, S., Sugiyama, N., Masutani, K., Sadanaga, A., Miyazaki, Y., Inoue, Y., Akahoshi, M., Katafuchi, R., Hirakata, H., Harada, M., Hamano, S., Nakashima, H. & Yoshida, H., 12 1 2005, : : Journal of Immunology. 175, 11, p. 7185-7192 8 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-27
Inbred MRL lpr Mouse
Membranous Glomerulonephritis
Glomerulonephritis
Lupus Nephritis
2004
17 引用 (Scopus)

Absence of association between the MCP-1 gene polymorphism and histological phenotype of lupus nephritis

Nakashima, H., Akahoshi, M., Shimizu, S., Inoue, Y., Miyake, K., Ninomiya, I., Igawa, T., Sadanaga, A., Otsuka, T. & Harada, M., 1 1 2004, : : Lupus. 13, 3, p. 165-167 3 p.

研究成果: ジャーナルへの寄稿記事

Lupus Nephritis
Chemokine CCL2
Glomerulonephritis
Membranous Glomerulonephritis
Phenotype
76 引用 (Scopus)

Anti-monocyte chemoattractant protein-1 gene therapy attenuates nephritis in MRL/lpr mice

Shimizu, S., Nakashima, H., Masutani, K., Inoue, Y., Miyake, K., Akahoshi, M., Tanaka, Y., Egashira, K., Hirakata, H., Otsuka, T. & Harada, M., 9 1 2004, : : Rheumatology. 43, 9, p. 1121-1128 8 p.

研究成果: ジャーナルへの寄稿記事

Inbred MRL lpr Mouse
Nephritis
Chemokine CCL2
Genetic Therapy
Lupus Nephritis
10 引用 (Scopus)

Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma

Hirota, T., Obara, K., Matsuda, A., Akahoshi, M., Nakashima, K., Hasegawa, K., Takahashi, N., Shimizu, M., Sekiguchi, H., Kokubo, M., Doi, S., Fujiwara, H., Miyatake, A., Fujita, K., Enomoto, T., Kishi, F., Suzuki, Y., Saito, H., Nakamura, Y., Shirakawa, T. および1人, Tamari, M., 1 1 2004, : : Journal of Human Genetics. 49, 7, p. 370-375 6 p.

研究成果: ジャーナルへの寄稿記事

Asthma
Interferon-gamma
Genes
Epithelial Cells
Proteins
64 引用 (Scopus)

Association between IFNA genotype and the risk of sarcoidosis

Akahoshi, M., Ishihara, M., Remus, N., Uno, K., Miyake, K., Hirota, T., Nakashima, K., Matsuda, A., Kanda, M., Enomoto, T., Ohno, S., Nakashima, H., Casanova, J. L., Hopkin, J. M., Tamari, M., Mao, X. Q. & Shirakawa, T., 4 1 2004, : : Human Genetics. 114, 5, p. 503-509 7 p.

研究成果: ジャーナルへの寄稿記事

Sarcoidosis
Genotype
Alleles
Tuberculosis
Genes
24 引用 (Scopus)

MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: Case report and review of the literature

Akahoshi, M., Yoshimoto, G., Nakashima, H., Miyake, K., Inoue, Y., Tanaka, Y., Tsukamoto, H., Horiuchi, T., Otsuka, T. & Harada, M., 6 1 2004, : : Modern Rheumatology. 14, 2, p. 179-183 5 p.

研究成果: ジャーナルへの寄稿記事

Antineutrophil Cytoplasmic Antibodies
Granulomatosis with Polyangiitis
Meningitis
Cranial Nerve Diseases
Headache Disorders
28 引用 (Scopus)

Novel Regulatory Mechanisms of CD40-Induced Prostanoid Synthesis by IL-4 and IL-10 in Human Monocytes

Inoue, Y., Otsuka, T., Niiro, H., Nagano, S., Arinobu, Y., Ogami, E., Akahoshi, M., Miyake, K., Ninomiya, I., Shimizu, S., Nakashima, H. & Harada, M., 2 15 2004, : : Journal of Immunology. 172, 4, p. 2147-2154 8 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-4
Interleukin-10
Prostaglandins
Monocytes
Phosphotransferases
40 引用 (Scopus)

Polymorphisms in ADAM33 are associated with allergic rhinitis due to Japanese cedar pollen

Cheng, L., Enomoto, T., Hirota, T., Shimizu, M., Takahashi, N., Akahoshi, M., Matsuda, A., Dake, Y., Doi, S., Enomoto, K., Yamasaki, A., Fukuda, S., Mao, X. Q., Hopkin, J. M., Tamari, M. & Shirakawa, T., 8 1 2004, : : Clinical and Experimental Allergy. 34, 8, p. 1192-1201 10 p.

研究成果: ジャーナルへの寄稿記事

Cryptomeria
Disintegrins
Metalloproteases
Pollen
Seasonal Allergic Rhinitis
2003
92 引用 (Scopus)

Influence of interleukin-12 receptor β1 polymorphisms on tuberculosis

Akahoshi, M., Nakashima, H., Miyake, K., Inoue, Y., Shimizu, S., Tanaka, Y., Okada, K., Otsuka, T. & Harada, M., 3 1 2003, : : Human Genetics. 112, 3, p. 237-243 7 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-12 Receptors
Tuberculosis
Alleles
Interleukin-12
Genes
3 引用 (Scopus)

Mutation detection using RT-PCR-RFLP.

Nakashima, H., Akahoshi, M. & Tanaka, Y., 1 1 2003, : : Methods in molecular biology (Clifton, N.J.). 226, p. 319-322 4 p.

研究成果: ジャーナルへの寄稿記事

DNA Primers
Reverse Transcriptase Polymerase Chain Reaction
Restriction Fragment Length Polymorphisms
Complementary DNA
Polymerase Chain Reaction
19 引用 (Scopus)

Strong polarization toward th1 immune response in ANCA-associated glomerulonephritis

Masutani, K., Tokumoto, M., Nakashima, H., Tsuruya, K., Kashiwagi, M., Kudoh, Y., Fukuda, K., Kanai, H., Akahoshi, M., Otsuka, T., Hirakata, H. & Ida, M., 6 1 2003, : : Clinical Nephrology. 59, 6, p. 395-405 11 p.

研究成果: ジャーナルへの寄稿記事

Antineutrophil Cytoplasmic Antibodies
Glomerulonephritis
Osteopontin
Macrophages
T-Lymphocytes
6 引用 (Scopus)

Systemic vasculitis associated with α1-antitrypsin deficiency

Takii, Y., Inoue, H., Karashima, E., Akahoshi, M., Furugo, I., Hattori, S., Yamanaka, M., Kinoshita, S., Hamasaki, N., Shimoda, K., Nakashima, H., Tsukamoto, H., Horiuchi, T., Otsuka, T. & Harada, M., 7 1 2003, : : Internal Medicine. 42, 7, p. 619-623 5 p.

研究成果: ジャーナルへの寄稿記事

Systemic Vasculitis
Peptide Hydrolases
Protease Inhibitors
Leukocyte Elastase
Serine Proteases
2002
112 引用 (Scopus)

Association between IL-4 genotype and IL-4 production in the Japanese population

Nakashima, H., Miyake, K., Inoue, Y., Shimizu, S., Akahoshi, M., Tanaka, Y., Otsuka, T. & Harada, M., 4 1 2002, : : Genes and Immunity. 3, 2, p. 107-109 3 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-4
Genotype
Population
Haplotypes
Cytokines
61 引用 (Scopus)

Genetically determined interferon-γ production influences the histological phenotype of lupus nephritis

Miyake, K., Nakashima, H., Akahoshi, M., Inoue, Y., Nagano, S., Tanaka, Y., Masutani, K., Hirakata, H., Gondo, H., Otsuka, T. & Harada, M., 6 8 2002, : : Rheumatology. 41, 5, p. 518-524 7 p.

研究成果: ジャーナルへの寄稿記事

Lupus Nephritis
Interferons
Phenotype
Genotype
Genes
44 引用 (Scopus)

Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: Involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines

Nagano, S., Otsuka, T., Niiro, H., Yamaoka, K., Arinobu, Y., Ogami, E., Akahoshi, M., Inoue, Y., Miyake, K., Nakashima, H., Niho, Y. & Harada, M., 8 7 2002, : : International Immunology. 14, 7, p. 733-740 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclooxygenase 2
Mitogen-Activated Protein Kinases
Lipopolysaccharides
Neutrophils
Anti-Inflammatory Agents
2001
181 引用 (Scopus)

Predominance of Th1 Immune Response in Diffuse Proliferative Lupus Nephritis

Masutani, K., Akahoshi, M., Tsuruya, K., Tokumoto, M., Ninomiya, T., Kohsaka, T., Fukuda, K., Kanai, H., Nakashima, H., Otsuka, T. & Hirakata, H., 1 1 2001, : : Arthritis and rheumatism. 44, 9, p. 2097-2106 10 p.

研究成果: ジャーナルへの寄稿記事

Lupus Nephritis
Systemic Lupus Erythematosus
Kidney
Nephritis
Th1-Th2 Balance
2000

Cytokine-producing T cells in systemic lupus erythematosus: Comment on the article by Akahoshi et al [2] (multiple letters)

Akahoshi, M., Nakashima, H. & Otsuka, T., 2000, : : Arthritis and Rheumatism. 43, 3, p. 711-712 2 p.

研究成果: ジャーナルへの寄稿レター

Helper-Inducer T-Lymphocytes
Systemic Lupus Erythematosus
Cytokines
T-Lymphocytes
1999
16 引用 (Scopus)

Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

Nakashima, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., 1 1 1999, : : Rheumatology. 38, 11, p. 1142-1144 3 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-10 Receptors
Systemic Lupus Erythematosus
Complementary DNA
Genotype
Genes
225 引用 (Scopus)

Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

Akahoshi, M., Nakashima, H., Tanaka, Y., Kohsaka, T., Nagano, S., Ohgami, E., Arinobu, Y., Yamaoka, K., Niiro, H., Shinozaki, M., Hirakata, H., Horiuchi, T., Otsuka, T. & Niho, Y., 8 1 1999, : : Arthritis and rheumatism. 42, 8, p. 1644-1648 5 p.

研究成果: ジャーナルへの寄稿記事

Th1-Th2 Balance
Helper-Inducer T-Lymphocytes
Systemic Lupus Erythematosus
Th2 Cells
Lupus Nephritis
53 引用 (Scopus)

The combination of polymorphisms within interferon-γ receptor I and receptor 2 associated with the risk of systemic lupus erythematosus

Nakashima, H., Inoue, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., 6 18 1999, : : FEBS Letters. 453, 1-2, p. 187-190 4 p.

研究成果: ジャーナルへの寄稿記事

Interferon Receptors
Polymorphism
Systemic Lupus Erythematosus
Amino Acids
Genotype
2 引用 (Scopus)

Two polymorphisms within interleukin-3 (hlL3) gene detected by mismatch PCR/RFLP

Nakashima, H., Otsuka, T., Ohba, Y., Akahoshi, M., Nagano, S., Ogami, E., Arinobu, Y., Miyake, K., Inoue, Y., Niiro, H., Kaji, Y. & Niho, Y., 1 1 1999, : : Genes and Immunity. 1, 2, p. 156-158 3 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-3
Nucleic Acid Databases
Restriction Fragment Length Polymorphisms
Thymine
Cytosine