Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1999 2019

フィルター
記事
2019
1 引用 (Scopus)

2-Oxo-histidine-containing dipeptides are functional oxidation products

Ihara, H., Kakihana, Y., Yamakage, A., Kai, K., Shibata, T., Nishida, M., Kenichi, Y. & Uchida, K., 1 1 2019, : : Journal of Biological Chemistry. 294, 4, p. 1279-1289 11 p.

研究成果: ジャーナルへの寄稿記事

Carnosine
Dipeptides
Histidine
Oxidation
Antioxidants
1 引用 (Scopus)

Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload

Nishimura, A., Shimoda, K., Tanaka, T., Toyama, T., Nishiyama, K., Shinkai, Y., Numaga-Tomita, T., Yamazaki, D., Kanda, Y., Akaike, T., Kumagai, Y. & Nishida, M., 1 1 2019, : : Science Signaling. 12, 587, eaaw1920.

研究成果: ジャーナルへの寄稿記事

Filamins
Hemodynamics
Cardiac Myocytes
Oxidation-Reduction
Rats
1 引用 (Scopus)

Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes

Nishiyama, K., Numaga-Tomita, T., Fujimoto, Y., Tanaka, T., Toyama, C., Nishimura, A., Yamashita, T., Naoya, M., Satoru, K., Azuma, Y. T., Ibuki, Y., Uchida, K., Ohdo, S. & Nishida, M., 9 1 2019, : : British Journal of Pharmacology. 176, 18, p. 3723-3738 16 p.

研究成果: ジャーナルへの寄稿記事

NADPH Oxidase
Doxorubicin
Tobacco Smoke Pollution
Proteins
Pharmaceutical Preparations

TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy

Sudi, S. B., Tanaka, T., Oda, S., Nishiyama, K., Nishimura, A., Sunggip, C., Mangmool, S., Numaga-Tomita, T. & Nishida, M., 12 1 2019, : : Scientific reports. 9, 1, 9785.

研究成果: ジャーナルへの寄稿記事

公開
Cardiac Myocytes
Malnutrition
Atrophy
Adenosine Triphosphate
Reactive Oxygen Species
1 引用 (Scopus)

TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN

Numaga-Tomita, T., Shimauchi, T., Oda, S., Tanaka, T., Nishiyama, K., Nishimura, A., Birnbaumer, L., Mori, Y. & Nishida, M., 9 1 2019, : : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 9, p. 9785-9796 12 p.

研究成果: ジャーナルへの寄稿記事

Cell membranes
Vascular Smooth Muscle
Membrane Potentials
Smooth Muscle Myocytes
Muscle
2018
10 引用 (Scopus)

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence

Nishimura, A., Shimauchi, T., Tanaka, T., Shimoda, K., Toyama, T., Kitajima, N., Ishikawa, T., Shindo, N., Numaga-Tomita, T., Yasuda, S., Sato, Y., Kuwahara, K., Kumagai, Y., Akaike, T., Ide, T., Ojida, A., Mori, Y. & Nishida, M., 11 13 2018, : : Science Signaling. 11, 556, eaat5185.

研究成果: ジャーナルへの寄稿記事

Filamins
Dynamins
Actins
Mitochondrial Dynamics
Proteins
3 引用 (Scopus)

Involvement of nitric oxide/reactive oxygen species signaling via 8-nitro-cGMP formation in 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells and rat cerebellar granule neurons

Masuda, K., Tsutsuki, H., Kasamatsu, S., Ida, T., Takata, T., Sugiura, K., Nishida, M., Watanabe, Y., Sawa, T., Akaike, T. & Ihara, H., 1 15 2018, : : Biochemical and Biophysical Research Communications. 495, 3, p. 2165-2170 6 p.

研究成果: ジャーナルへの寄稿記事

1-Methyl-4-phenylpyridinium
PC12 Cells
Neurons
Rats
Reactive Oxygen Species

New strategies for exercise-mimetic medication

Oda, S., Numaga-Tomita, T. & Nishida, M., 1 1 2018, : : Yakugaku Zasshi. 138, 10, p. 1257-1262 6 p.

研究成果: ジャーナルへの寄稿記事

Exercise Therapy
Exercise
Reactive Oxygen Species
NADP
Vascular Smooth Muscle

Prolonged stimulation of β2-adrenergic receptor with β2-agonists impairs insulin actions in H9c2 cells

Parichatikanond, W., Nishimura, A., Nishida, M. & Mangmool, S., 11 1 2018, : : Journal of Pharmacological Sciences. 138, 3, p. 184-191 8 p.

研究成果: ジャーナルへの寄稿記事

Adrenergic Receptors
Insulin Resistance
Insulin
Glucose
Smooth Muscle Myocytes
11 引用 (Scopus)

TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes

Yamaguchi, Y., Iribe, G., Kaneko, T., Takahashi, K., Numaga-Tomita, T., Nishida, M., Birnbaumer, L. & Naruse, K., 3 1 2018, : : Journal of Physiological Sciences. 68, 2, p. 153-164 12 p.

研究成果: ジャーナルへの寄稿記事

Angiotensin Type 1 Receptor
Cardiac Myocytes
Angiotensin II Type 1 Receptor Blockers
Type C Phospholipases
Knockout Mice
6 引用 (Scopus)

TRPC5-eNOS axis negatively regulates ATP-induced cardiomyocyte hypertrophy

Sunggip, C., Shimoda, K., Oda, S., Tanaka, T., Nishiyama, K., Mangmool, S., Nishimura, A., Numaga-Tomita, T. & Nishida, M., 5 22 2018, : : Frontiers in Pharmacology. 9, MAY, 523.

研究成果: ジャーナルへの寄稿記事

Cardiac Myocytes
Hypertrophy
Adenosine Triphosphate
NFATC Transcription Factors
Cyclic GMP-Dependent Protein Kinases
2017
6 引用 (Scopus)

A protease-activated receptor-1 antagonist protects against podocyte injury in a mouse model of nephropathy

Guan, Y., Nakano, D., Zhang, Y., Li, L., Liu, W., Nishida, M., Kuwabara, T., Morishita, A., Hitomi, H., Mori, K., Mukoyama, M., Masaki, T., Hirano, K. & Nishiyama, A., 10 1 2017, : : Journal of Pharmacological Sciences. 135, 2, p. 81-88 8 p.

研究成果: ジャーナルへの寄稿記事

PAR-1 Receptor
Podocytes
Doxorubicin
Wounds and Injuries
Kidney
89 引用 (Scopus)

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Akaike, T., Ida, T., Wei, F. Y., Nishida, M., Kumagai, Y., Alam, M. M., Ihara, H., Sawa, T., Matsunaga, T., Kasamatsu, S., Nishimura, A., Morita, M., Tomizawa, K., Nishimura, A., Watanabe, S., Inaba, K., Shima, H., Tanuma, N., Jung, M., Fujii, S. および6人, Watanabe, Y., Ohmuraya, M., Nagy, P., Feelisch, M., Fukuto, J. M. & Motohashi, H., 12 1 2017, : : Nature communications. 8, 1, 1177.

研究成果: ジャーナルへの寄稿記事

cysteinyl-tRNA synthetase
cysteine
Energy Metabolism
Cysteine
Cysteine Synthase
11 引用 (Scopus)

Exposure to electrophiles impairs reactive persulfide-dependent redox signaling in neuronal cells

Ihara, H., Kasamatsu, S., Kitamura, A., Nishimura, A., Tsutsuki, H., Ida, T., Ishizaki, K., Toyama, T., Yoshida, E., Hamid, H. A., Jung, M., Matsunaga, T., Fujii, S., Sawa, T., Nishida, M., Kumagai, Y. & Akaike, T., 1 1 2017, : : Chemical Research in Toxicology. 30, 9, p. 1673-1684 12 p.

研究成果: ジャーナルへの寄稿記事

Oxidation-Reduction
Chemical activation
Wounds and Injuries
Metabolites
Sulfhydryl Compounds
17 引用 (Scopus)

MiR30-GALNT1/2 axis-mediated glycosylation contributes to the increased secretion of inactive human prohormone for brain natriuretic peptide (proBNP) from failing hearts

Nakagawa, Y., Nishikimi, T., Kuwahara, K., Fujishima, A., Oka, S., Tsutamoto, T., Kinoshita, H., Nakao, K., Cho, K., Inazumi, H., Okamoto, H., Nishida, M., Kato, T., Fukushima, H., Yamashita, J. K., Wijnen, W. J., Creemers, E. E., Kangawa, K., Minamino, N., Nakao, K. および1人, Kimura, T., 1 1 2017, : : Journal of the American Heart Association. 6, 2, e003601.

研究成果: ジャーナルへの寄稿記事

Brain Natriuretic Peptide
Glycosylation
Heart Failure
MicroRNAs
Cyclic GMP

Purinergic signaling in cardiovascular system

Nishimura, A. & Nishida, M., 1 1 2017, : : Folia Pharmacologica Japonica. 149, 2, p. 84-90 7 p.

研究成果: ジャーナルへの寄稿記事

Uracil
Cardiovascular System
Adenosine
Signal Transduction
Hypertension
20 引用 (Scopus)

Stimulation of adenosine A2B receptor inhibits endothelin-1-induced cardiac Fibroblast proliferation and α-smooth muscle actin synthesis through the cAMP/Epac/PI3K/Akt-signaling pathway

Phosri, S., Arieyawong, A., Bunrukchai, K., Parichatikanond, W., Nishimura, A., Nishida, M. & Mangmool, S., 6 30 2017, : : Frontiers in Pharmacology. 8, JUN, 428.

研究成果: ジャーナルへの寄稿記事

Endothelin A Receptors
Phosphatidylinositol 3-Kinases
Adenosine
Endothelin-1
Smooth Muscle
9 引用 (Scopus)

TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy

Shimauchi, T., Numaga-Tomita, T., Ito, T., Nishimura, A., Matsukane, R., Oda, S., Hoka, S., Ide, T., Koitabashi, N., Uchida, K., Sumimoto, H., Mori, Y. & Nishida, M., 8 3 2017, : : JCI Insight. 2, 15

研究成果: ジャーナルへの寄稿記事

公開
NADPH Oxidase
Doxorubicin
Atrophy
Cardiac Myocytes
Compliance
3 引用 (Scopus)

TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

Oda, S., Numaga-Tomita, T., Kitajima, N., Toyama, T., Harada, E., Shimauchi, T., Nishimura, A., Ishikawa, T., Kumagai, Y., Birnbaumer, L. & Nishida, M., 12 1 2017, : : Scientific reports. 7, 1, 7511.

研究成果: ジャーナルへの寄稿記事

NADPH Oxidase
Hyperglycemia
Heart Failure
Proteins
Reactive Oxygen Species
2016
20 引用 (Scopus)

Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells

Unoki, T., Abiko, Y., Toyama, T., Uehara, T., Tsuboi, K., Nishida, M., Kaji, T. & Kumagai, Y., 6 30 2016, : : Scientific reports. 6, 28944.

研究成果: ジャーナルへの寄稿記事

Signal Transduction
Cell Survival
Apoptosis Regulatory Proteins
Neuroblastoma
Phosphatidylinositol 3-Kinases
31 引用 (Scopus)

Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension

Nishimura, A., Sunggip, C., Tozaki-Saitoh, H., Shimauchi, T., Numaga-Tomita, T., Hirano, K., Ide, T., Boeynaems, J. M., Kurose, H., Tsuda, M., Robaye, B., Inoue, K. & Nishida, M., 1 19 2016, : : Science Signaling. 9, 411, aac9187.

研究成果: ジャーナルへの寄稿記事

Purinergic Receptors
Angiotensin Type 1 Receptor
Angiotensin II
Hypertension
Arrestin
7 引用 (Scopus)

Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compoundss

Sawamura, S., Hatano, M., Takada, Y., Hino, K., Kawamura, T., Tanikawa, J., Nakagawa, H., Hase, H., Nakao, A., Hirano, M., Rotrattanadumrong, R., Kiyonaka, S., Mori, M. X., Nishida, M., Hu, Y., Inoue, R., Nagata, R. & Mori, Y., 3 1 2016, : : Molecular Pharmacology. 89, 3, p. 348-363 16 p.

研究成果: ジャーナルへの寄稿記事

Transient Receptor Potential Channels
Diglycerides
Brain-Derived Neurotrophic Factor
Cations
Neurons
13 引用 (Scopus)

Sustained βAR stimulation mediates cardiac insulin resistance in a PKA-dependent manner

Mangmool, S., Denkaew, T., Phosri, S., Pinthong, D., Parichatikanond, W., Shimauchi, T. & Nishida, M., 1 1 2016, : : Molecular Endocrinology. 30, 1, p. 118-132 15 p.

研究成果: ジャーナルへの寄稿記事

Adrenergic Receptors
Insulin Resistance
Cyclic AMP-Dependent Protein Kinases
Insulin
Cardiac Myocytes
3 引用 (Scopus)

Synthesis of radioiodinated probes to evaluate the biodistribution of a potent TRPC3 inhibitor

Hagimori, M., Murakami, T., Shimizu, K., Nishida, M., Ohshima, T. & Mukai, T., 1 1 2016, : : MedChemComm. 7, 5, p. 1003-1006 4 p.

研究成果: ジャーナルへの寄稿記事

Therapeutic Human Experimentation
HEK293 Cells
Treatment Failure
Heart Failure
Cell Membrane
2 引用 (Scopus)

TRPC3 amplifies B-cell receptor-induced ERK signalling via protein kinase D-dependent Rap1 activation

Numaga-Tomita, T., Nishida, M., Putney, J. W. & Mori, Y., 1 15 2016, : : Biochemical Journal. 473, 2, p. 201-210 10 p.

研究成果: ジャーナルへの寄稿記事

Extracellular Signal-Regulated MAP Kinases
B-Lymphocytes
Chemical activation
Cells
Lymphocytes
20 引用 (Scopus)

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis

Numaga-Tomita, T., Kitajima, N., Kuroda, T., Nishimura, A., Miyano, K., Yasuda, S., Kuwahara, K., Sato, Y., Ide, T., Birnbaumer, L., Sumimoto, H., Mori, Y. & Nishida, M., 12 19 2016, : : Scientific reports. 6, 39383.

研究成果: ジャーナルへの寄稿記事

Cardiac Myocytes
Fibrosis
Microtubules
Pressure
Fibroblasts
33 引用 (Scopus)

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

Kitajima, N., Numaga-Tomita, T., Watanabe, M., Kuroda, T., Nishimura, A., Miyano, K., Yasuda, S., Kuwahara, K., Sato, Y., Ide, T., Birnbaumer, L., Sumimoto, H., Mori, Y. & Nishida, M., 11 11 2016, : : Scientific reports. 6, 37001.

研究成果: ジャーナルへの寄稿記事

NADPH Oxidase
Reactive Oxygen Species
Physiological Adaptation
Proteasome Endopeptidase Complex
Cardiac Myocytes
2015
19 引用 (Scopus)

Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases

Gentry, L. R., Nishimura, A., Cox, A. D., Martin, T. D., Tsygankov, D., Nishida, M., Elston, T. C. & Der, C. J., 9 11 2015, : : Journal of Biological Chemistry. 290, 37, p. 22851-22861 11 p.

研究成果: ジャーナルへの寄稿記事

Endopeptidases
GTP Phosphohydrolases
Post Translational Protein Processing
Protein Isoforms
Cell Membrane
12 引用 (Scopus)

Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress

Shinkai, Y., Abiko, Y., Ida, T., Miura, T., Kakehashi, H., Ishii, I., Nishida, M., Sawa, T., Akaike, T. & Kumagai, Y., 5 18 2015, : : Chemical Research in Toxicology. 28, 5, p. 838-847 10 p.

研究成果: ジャーナルへの寄稿記事

Sulfenic Acids
Oxidative stress
Sulfur
Oxidative Stress
Chemical activation
2014

Establishment of a novel therapeutic strategy for heart failure based on the mechanism underlying maintenance of redox homeostasis by reactive sulfur species

Nishida, M., Toyama, T., Kumagai, Y. & Numaga-Tomita, T., 1 1 2014, : : Yakugaku Zasshi. 134, 12, p. 1239-1243 5 p.

研究成果: ジャーナルへの寄稿記事

Sulfur
Oxidation-Reduction
Nitric Oxide
Homeostasis
Heart Failure
17 引用 (Scopus)

Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure

Yamada, Y., Kinoshita, H., Kuwahara, K., Nakagawa, Y., Kuwabara, Y., Minami, T., Yamada, C., Shibata, J., Nakao, K., Cho, K., Arai, Y., Yasuno, S., Nishikimi, T., Ueshima, K., Kamakura, S., Nishida, M., Kiyonaka, S., Mori, Y., Kimura, T., Kangawa, K. および1人, Nakao, K., 10 1 2014, : : Cardiovascular research. 104, 1, p. 183-193 11 p.

研究成果: ジャーナルへの寄稿記事

Autonomic Pathways
Cardiac Arrhythmias
Heart Failure
Sudden Death
Nitrendipine
2013
18 引用 (Scopus)

Atrial natriuretic peptide-mediated inhibition of microcirculatory endothelial Ca2+ and permeability response to histamine involves cGMP-dependent protein kinase i and TRPC6 channels

Chen, W., Oberwinkler, H., Werner, F., Ganer, B., Nakagawa, H., Feil, R., Hofmann, F., Schlossmann, J., Dietrich, A., Gudermann, T., Nishida, M., Del Galdo, S., Wieland, T. & Kuhn, M., 9 1 2013, : : Arteriosclerosis, thrombosis, and vascular biology. 33, 9, p. 2121-2129 9 p.

研究成果: ジャーナルへの寄稿記事

Cyclic GMP-Dependent Protein Kinase Type I
Cyclic GMP-Dependent Protein Kinases
Atrial Natriuretic Factor
Histamine
Permeability
32 引用 (Scopus)

GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance

Nakaya, M., Tajima, M., Kosako, H., Nakaya, T., Hashimoto, A., Watari, K., Nishihara, H., Ohba, M., Komiya, S., Tani, N., Nishida, M., Taniguchi, H., Sato, Y., Matsumoto, M., Tsuda, M., Kuroda, M., Inoue, K. & Kurose, H., 3 11 2013, : : Nature communications. 4, 1532.

研究成果: ジャーナルへの寄稿記事

clearances
Autoimmune Diseases
mice
Cells
proteins
8 引用 (Scopus)

Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice

Nishida, M., Ishikawa, T., Saiki, S., Sunggip, C., Aritomi, S., Harada, E., Kuwahara, K., Hirano, K., Mori, Y. & Kim-Mitsuyama, S., 5 3 2013, : : Biochemical and Biophysical Research Communications. 434, 2, p. 210-216 7 p.

研究成果: ジャーナルへの寄稿記事

Oxidative stress
Endothelial cells
Angiotensin II
Oxidative Stress
Endothelial Cells
29 引用 (Scopus)

β-arrestin2 in Infiltrated Macrophages Inhibits Excessive Inflammation after Myocardial Infarction

Watari, K., Michio, N., Nishida, M., Kim, K. M. & Kurose, H., 7 8 2013, : : PloS one. 8, 7, e68351.

研究成果: ジャーナルへの寄稿記事

Macrophages
myocardial infarction
Knockout Mice
macrophages
inflammation
2012
177 引用 (Scopus)

Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

Nishida, M., Sawa, T., Kitajima, N., Ono, K., Inoue, H., Ihara, H., Motohashi, H., Yamamoto, M., Suematsu, M., Kurose, H., Van Der Vliet, A., Freeman, B. A., Shibata, T., Uchida, K., Kumagai, Y. & Akaike, T., 1 1 2012, : : Nature Chemical Biology. 8, 8, p. 714-724 11 p.

研究成果: ジャーナルへの寄稿記事

Hydrogen Sulfide
Oxidation-Reduction
Anions
Myocardial Infarction
Cell Aging
35 引用 (Scopus)

Induction of cardiac fibrosis by β-blocker in G protein-independent and G protein-coupled receptor kinase 5/β-arrestin2-dependent signaling pathways

Nakaya, M., Chikura, S., Watari, K., Mizuno, N., Mochinaga, K., Mangmool, S., Koyanagi, S., Ohdo, S., Sato, Y., Ide, T., Nishida, M. & Kurose, H., 10 12 2012, : : Journal of Biological Chemistry. 287, 42, p. 35669-35677 9 p.

研究成果: ジャーナルへの寄稿記事

G-Protein-Coupled Receptor Kinase 5
Metoprolol
GTP-Binding Proteins
Fibrosis
Arrestin
37 引用 (Scopus)

Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis

Kan-O, M., Takeya, R., Abe, T., Kitajima, N., Nishida, M., Tominaga, R., Kurose, H. & Sumimoto, H., 9 15 2012, : : Biology Open. 1, 9, p. 889-896 8 p.

研究成果: ジャーナルへの寄稿記事

Muscle Development
muscle development
Actins
heart
Myofibrils
17 引用 (Scopus)

Recombinant mitochondrial transcription factor A protein inhibits nuclear factor of activated T cells signaling and attenuates pathological hypertrophy of cardiac myocytes

Fujino, T., Ide, T., Yoshida, M., Onitsuka, K., Tanaka, A., Hata, Y., Nishida, M., Takehara, T., Kanemaru, T., Kitajima, N., Takazaki, S., Kurose, H., Kang, D. & Sunagawa, K., 7 1 2012, : : Mitochondrion. 12, 4, p. 449-458 10 p.

研究成果: ジャーナルへの寄稿記事

NFATC Transcription Factors
Cardiac Myocytes
Hypertrophy
Mitochondrial DNA
Proteins
2011
26 引用 (Scopus)

Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel

Nishioka, K., Nishida, M., Ariyoshi, M., Jian, Z., Saiki, S., Hirano, M., Nakaya, M., Sato, Y., Kita, S., Iwamoto, T., Hirano, K., Inoue, R. & Kurose, H., 10 1 2011, : : Arteriosclerosis, thrombosis, and vascular biology. 31, 10, p. 2278-2286 9 p.

研究成果: ジャーナルへの寄稿記事

Cyclic AMP-Dependent Protein Kinases
Vasoconstriction
Angiotensin II
Phosphorylation
Transient Receptor Potential Channels

Determining the activation of rho as an index of receptor coupling to G12/13 proteins

Michio, N., Ohba, M., Nishida, M. & Kurose, H., 1 1 2011, : : Methods in Molecular Biology. 746, p. 317-327 11 p.

研究成果: ジャーナルへの寄稿記事

G12-G13 GTP-Binding Protein alpha Subunits
GTP-Binding Proteins
Heterotrimeric GTP-Binding Proteins
Rho Guanine Nucleotide Exchange Factors
Guanine Nucleotide Exchange Factors
4 引用 (Scopus)

Dual signaling pathways of arterial constriction by extracellular uridine 5′-triphosphate in the rat

Sugihara, M., Morita, H., Matsuda, M., Umebayashi, H., Kajioka, S., Ito, S., Nishida, M., Inoue, R., Futatsuki, T., Yamazaki, J., Mori, Y., Inoue, R., Ito, Y., Abe, K. & Hirata, M., 3 24 2011, : : Journal of Pharmacological Sciences. 115, 3, p. 293-308 16 p.

研究成果: ジャーナルへの寄稿記事

Uridine Triphosphate
Constriction
Purinergic P2X1 Receptors
Adenosine Triphosphate
Muscle Cells
38 引用 (Scopus)

Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-κB

Nishida, M., Ogushi, M., Suda, R., Toyotaka, M., Saiki, S., Kitajima, N., Nakaya, M., Kim, K. M., Ide, T., Sato, Y., Inoue, K. & Kurose, H., 4 19 2011, : : Proceedings of the National Academy of Sciences of the United States of America. 108, 16, p. 6662-6667 6 p.

研究成果: ジャーナルへの寄稿記事

Purinergic P2Y2 Receptors
Angiotensin Type 1 Receptor
Down-Regulation
Adenosine Triphosphate
Arrestins
8 引用 (Scopus)

Mechanism of the cardioprotective effects of docetaxel pre-administration against adriamycin-induced cardiotoxicity

Tomonari, M., To, H., Nishida, M., Mishima, T., Sasaki, H. & Kurose, H., 3 24 2011, : : Journal of Pharmacological Sciences. 115, 3, p. 336-345 10 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Doxorubicin
Poisons
Cardiotoxicity
Pharmacokinetics
15 引用 (Scopus)

Regulation of Angiotensin II receptor signaling by cysteine modification of NF-κB

Nishida, M., Kitajima, N., Saiki, S., Nakaya, M. & Kurose, H., 8 1 2011, : : Nitric Oxide - Biology and Chemistry. 25, 2, p. 112-117 6 p.

研究成果: ジャーナルへの寄稿記事

Angiotensin Receptors
Cysteine
Reactive Oxygen Species
Angiotensin II
Reactive Nitrogen Species
43 引用 (Scopus)

TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts

Kitajima, N., Watanabe, K., Morimoto, S., Sato, Y., Kiyonaka, S., Hoshijima, M., Ikeda, Y., Nakaya, M., Ide, T., Mori, Y., Kurose, H. & Nishida, M., 5 27 2011, : : Biochemical and Biophysical Research Communications. 409, 1, p. 108-113 6 p.

研究成果: ジャーナルへの寄稿記事

Dilated Cardiomyopathy
Calcium-Calmodulin-Dependent Protein Kinases
Reactive Oxygen Species
NADPH Oxidase
Calmodulin
2010
49 引用 (Scopus)

Ca2+ influx and protein scaffolding via TRPC3 sustain PKCβ and ERK activation in B cells

Numaga, T., Nishida, M., Kiyonaka, S., Kato, K., Katano, M., Mori, E., Kurosaki, T., Inoue, R., Hikida, M., Putney, J. W. & Mori, Y., 3 15 2010, : : Journal of Cell Science. 123, 6, p. 927-938 12 p.

研究成果: ジャーナルへの寄稿記事

Diglycerides
Extracellular Signal-Regulated MAP Kinases
Protein Kinase C
B-Lymphocytes
Cell Membrane
92 引用 (Scopus)

Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-a signaling in the heart

Kinoshita, H., Kuwahara, K., Nishida, M., Jian, Z., Rong, X., Kiyonaka, S., Kuwabara, Y., Kurose, H., Inoue, R., Mori, Y., Li, Y., Nakagawa, Y., Usami, S., Fujiwara, M., Yamada, Y., Minami, T., Ueshima, K. & Nakao, K., 6 25 2010, : : Circulation research. 106, 12, p. 1849-1860 12 p.

研究成果: ジャーナルへの寄稿記事

Natriuretic Peptides
Guanylate Cyclase
Atrial Natriuretic Factor
Cardiomegaly
NFATC Transcription Factors
30 引用 (Scopus)

Pertussis toxin up-regulates angiotensin type 1 receptors through toll-like receptor 4-mediated Rac activation

Nishida, M., Suda, R., Nagamatsu, Y., Tanabe, S., Onohara, N., Nakaya, M., Kanaho, Y., Shibata, T., Uchida, K., Sumimoto, H., Sato, Y. & Kurose, H., 5 14 2010, : : Journal of Biological Chemistry. 285, 20, p. 15268-15277 10 p.

研究成果: ジャーナルへの寄稿記事

Angiotensin Type 1 Receptor
Toll-Like Receptor 4
Pertussis Toxin
Up-Regulation
Chemical activation
62 引用 (Scopus)

Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition

Nishida, M., Watanabe, K., Sato, Y., Nakaya, M., Kitajima, N., Ide, T., Inoue, R. & Kurose, H., 4 23 2010, : : Journal of Biological Chemistry. 285, 17, p. 13244-13253 10 p.

研究成果: ジャーナルへの寄稿記事

Type 5 Cyclic Nucleotide Phosphodiesterases
Phosphorylation
Cyclic GMP-Dependent Protein Kinases
Cardiomegaly
Chemical activation