• 4504 引用
  • 39 h指数
20002020

Research output per year

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
記事
2007

Prenatal exposure to 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) promotes anxiogenic behavior in rats

Orito, K., Gotanda, N., Murakami, M., Ikeda, T., Egashira, N., Mishima, K. & Fujiwara, M., 6 5 2007, : : Tohoku Journal of Experimental Medicine. 212, 2, p. 151-157 7 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Repeated treatment with cannabidiol but not Δ9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance

Hayakawa, K., Mishima, K., Nozako, M., Ogata, A., Hazekawa, M., Liu, A. X., Fujioka, M., Abe, K., Hasebe, N., Egashira, N., Iwasaki, K. & Fujiwara, M., 3 1 2007, : : Neuropharmacology. 52, 4, p. 1079-1087 9 p.

研究成果: ジャーナルへの寄稿記事

59 引用 (Scopus)

Tokishakuyakusan: Pharmacological evidence for neuroactive and neuroprotective actions

Fujiwara, M., Egashira, N., Mishima, K., Iwasaki, K. & Egashira, N., 1 1 2007, : : Journal of Traditional Medicines. 24, 5, p. 149-155 7 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Δ9-tetrahydrocannabinol (Δ9-THC) prevents cerebral infarction via hypothalamic-independent hypothermia

Hayakawa, K., Mishima, K., Nozako, M., Hazekawa, M., Ogata, A., Fujioka, M., Harada, K., Mishima, S., Orito, K., Egashira, N., Iwasaki, K. & Fujiwara, M., 3 27 2007, : : Life Sciences. 80, 16, p. 1466-1471 6 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)
2006

Antagonistic effects of methanolic extract of Polygala telephioides on morphine responses in mice

Egashira, N., Li, J. C., Mizuki, A., Yamauchi, K., Matsuda, T., Osajima, M., Matsushita, M., Mishima, K., Iwasaki, K., Hara, S., Ono, N., Nishimura, R., Nohara, T. & Fujiwara, M., 3 8 2006, : : Journal of Ethnopharmacology. 104, 1-2, p. 193-198 6 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Antipsychotics improve Δ9-tetrahydrocannabinol-induced impairment of the prepulse inhibition of the startle reflex in mice

Nagai, H., Egashira, N., Sano, K., Ogata, A., Mizuki, A., Mishima, K., Iwasaki, K., Shoyama, Y., Nishimura, R. & Fujiwara, M., 6 1 2006, : : Pharmacology Biochemistry and Behavior. 84, 2, p. 330-336 7 p.

研究成果: ジャーナルへの寄稿記事

54 引用 (Scopus)

Cerebral ischemia combined with β-amyloid impairs spatial memory in the eight-arm radial maze task in rats

Iwasaki, K., Egashira, N., Hatip-Al-Khatib, I., Akiyoshi, Y., Arai, T., Takagaki, Y., Watanabe, T., Mishima, K. & Fujiwara, M., 6 30 2006, : : Brain Research. 1097, 1, p. 216-223 8 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Cortical neuronal and glial pathology in TgTauP301L transgenic mice: Neuronal degeneration, memory disturbance, and phenotypic variation

Murakami, T., Paitel, E., Kawarabayashi, T., Ikeda, M., Chishti, M. A., Janus, C., Matsubara, E., Sasaki, A., Kawarai, T., Phinney, A. L., Harigaya, Y., Horne, P., Egashira, N., Mishima, K., Hanna, A., Yang, J., Iwasaki, K., Takahashi, M., Fujiwara, M., Ishiguro, K. および6人, Bergeron, C., Carlson, G. A., Abe, K., Westaway, D., St. George-Hyslop, P. & Shoji, M., 10 2006, : : American Journal of Pathology. 169, 4, p. 1365-1375 11 p.

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)

Effects of mood stabilizers on the disruption of prepulse inhibition induced by apomorphine or dizocilpine in mice

Umeda, K., Suemaru, K., Todo, N., Egashira, N., Mishima, K., Iwasaki, K., Fujiwara, M. & Araki, H., 12 28 2006, : : European Journal of Pharmacology. 553, 1-3, p. 157-162 6 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male mice

Umehara, F., Mishima, K., Egashira, N., Ogata, A., Iwasaki, K. & Fujiwara, M., 11 1 2006, : : Behavioural Brain Research. 174, 1, p. 167-173 7 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Investigation of mechanisms mediating 8-OH-DPAT-induced impairment of spatial memory: Involvement of 5-HT1A receptors in the dorsal hippocampus in rats

Egashira, N., Yano, A., Ishigami, N., Mishima, K., Iwasaki, K., Fujioka, M., Matsushita, M., Nishimura, R. & Fujiwara, M., 1 19 2006, : : Brain Research. 1069, 1, p. 54-62 9 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

Involvement of 5-hydroxytryptamine1A receptors in Δ9-tetrahydrocannabinol-induced catalepsy-like immobilization in mice

Egashira, N., Matsuda, T., Koushi, E., Mishima, K., Iwasaki, K., Shoyama, Y. & Fujiwara, M., 11 21 2006, : : European Journal of Pharmacology. 550, 1-3, p. 117-122 6 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)

Low dose citalopram reverses memory impairment and electroconvulsive shock-induced immobilization

Egashira, N., Matsumoto, Y., Mishima, K., Iwasaki, K., Fujioka, M., Matsushita, M., Shoyama, Y., Nishimura, R. & Fujiwara, M., 1 1 2006, : : Pharmacology Biochemistry and Behavior. 83, 1, p. 161-167 7 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

Rehabilitative training tasks improve spatial learning impairment in the water maze following hypoxic-ischemic insult in neonatal rats

Ikeda, T., Mishima, K., Aoo, N., Harada, K., An, X. L., Egashira, N., Iwasaki, K., Fujiwara, M. & Ikenoue, T., 1 1 2006, : : Pediatric Research. 59, 1, p. 61-65 5 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)
2005

Altered depression-related behavior and neurochemical changes in serotonergic neurons in mutant R406W human tau transgenic mice

Egashira, N., Iwasaki, K., Takashima, A., Watanabe, T., Kawabe, H., Matsuda, T., Mishima, K., Chidori, S., Nishimura, R. & Fujiwara, M., 10 12 2005, : : Brain Research. 1059, 1, p. 7-12 6 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism

Mishima, K., Hayakawa, K., Abe, K., Ikeda, T., Egashira, N., Iwasaki, K. & Fujiwara, M., 5 1 2005, : : Stroke. 36, 5, p. 1071-1076 6 p.

研究成果: ジャーナルへの寄稿記事

121 引用 (Scopus)

Dexamethasone prevents long-lasting learning impairment following a combination of lipopolysaccharide and hypoxia-ischemia in neonatal rats

Ikeda, T., Mishima, K., Aoo, N., Liu, A. X., Egashira, N., Iwasaki, K., Fujiwara, M. & Ikenoue, T., 3 2005, : : American Journal of Obstetrics and Gynecology. 192, 3, p. 719-726 8 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Differential effects of buckwheat and kudingcha extract on neuronal damage in cultured hippocampal neurons and spatial memory impairment induced by scopolamine in an eight-arm radial maze

Pu, F., Mishima, K., Irie, K., Egashira, N., Ishibashi, D., Matsumoto, Y., Ikeda, T., Iwasaki, K., Fujii, H., Kosuna, K. & Fujiwara, M., 12 2005, : : Journal of Health Science. 51, 6, p. 636-644 9 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Disruption of the prepulse inhibition of the startle reflex in vasopressin V1b receptor knockout mice: Reversal by antipsychotic drugs

Egashira, N., Tanoue, A., Higashihara, F., Fuchigami, H., Sano, K., Mishima, K., Fukue, Y., Nagai, H., Takano, Y., Tsujimoto, G., Stemmelin, J., Griebel, G., Iwasaki, K., Ikeda, T., Nishimura, R. & Fujiwara, M., 11 1 2005, : : Neuropsychopharmacology. 30, 11, p. 1996-2005 10 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats

Hatip-Al-Khatib, I., Iwasaki, K., Yoshimitsu, Y., Arai, T., Egashira, N., Mishima, K., Ikeda, T. & Fujiwara, M., 12 1 2005, : : British Journal of Pharmacology. 145, 8, p. 1035-1044 10 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

Hypoxia-ischemic insult in neonatal rats induced slowly progressive brain damage related to memory impairment

Mishima, K., Ikeda, T., Aoo, N., Takai, N., Takahashi, S., Egashira, N., Ikenoue, T., Iwasaki, K. & Fujiwara, M., 3 16 2005, : : Neuroscience Letters. 376, 3, p. 194-199 6 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)

Implantation of encapsulated glial cell line-derived neurotrophic factor-secreting cells prevents long-lasting learning impairment following neonatal hypoxic-ischemic brain insult in rats

Katsuragi, S., Ikeda, T., Date, I., Shingo, T., Yasuhara, T., Mishima, K., Aoo, N., Harada, K., Egashira, N., Iwasaki, K., Fujiwara, M. & Ikenoue, T., 4 2005, : : American Journal of Obstetrics and Gynecology. 192, 4, p. 1028-1037 10 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: Implications for obsessive-compulsive disorder

Matsushita, M., Egashira, N., Harada, S., Okuno, R., Mishima, K., Iwasaki, K., Nishimura, R. & Fujiwara, M., 11 7 2005, : : Journal of Pharmacological Sciences. 99, 2, p. 154-159 6 p.

研究成果: ジャーナルへの寄稿記事

44 引用 (Scopus)

Post-ischemic treatment with Toki-shakuyaku-san (Tang-Gui-Shao-Yao-San) prevents the impairment of spatial memory induced by repeated cerebral ischemia in rats

Pu, F., Mishima, K., Egashira, N., Akiyoshi, Y., Liu, A. X., Sano, K., Irie, K., Ishibashi, D., Hatip-Al-Khatib, I., Iwasaki, K., Kurauchi, K., Iwasaki, K. & Fujiwara, M., 7 13 2005, : : American Journal of Chinese Medicine. 33, 3, p. 475-489 15 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)

Protective effect of Toki-shakuyaku-san on amyloid β25-35- induced neuronal damage in cultured rat cortical neurons

Egashira, N., Iwasaki, K., Akiyoshi, Y., Takagaki, Y., Hatip-Al-Khatib, I., Mishima, K., Kurauchi, K., Ikeda, T. & Fujiwara, M., 5 1 2005, : : Phytotherapy Research. 19, 5, p. 450-453 4 p.

研究成果: ジャーナルへの寄稿記事

28 引用 (Scopus)

Short-term administration of a new free radical scavenger, edaravone, is more effective than its long-term administration for the treatment of neonatal hypoxic-ischemic encephalopathy

Noor, J. I., Ikeda, T., Mishima, K., Aoo, N., Ohta, S., Egashira, N., Iwasaki, K., Fujiwara, M. & Ikenoue, T., 11 1 2005, : : Stroke. 36, 11, p. 2468-2474 7 p.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)
2004

Anandamide inhibits the DOI-induced head-twitch response in mice

Egashira, N., Mishima, K., Uchida, T., Hasebe, N., Nagai, H., Mizuki, A., Iwasaki, K., Ishii, H., Nishimura, R., Shoyama, Y. & Fujiwara, M., 2 1 2004, : : Psychopharmacology. 171, 4, p. 382-389 8 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Cannabidiol prevents infarction via the non-CBI cannabinoid receptor mechanism

Hayakawa, K., Mishima, K., Abe, K., Hasebe, N., Takamatsu, F., Yasuda, H., Ikeda, T., Inui, K., Egashira, N., Iwasaki, K. & Fujiwara, M., 10 25 2004, : : NeuroReport. 15, 15, p. 2381-2385 5 p.

研究成果: ジャーナルへの寄稿記事

45 引用 (Scopus)

Characteristics of behavioral abnormalities in α1d- adrenoceptors deficient mice

Mishima, K., Tanoue, A., Tsuda, M., Hasebe, N., Fukue, Y., Egashira, N., Takano, Y., Kamiya, H. O., Tsujimoto, G., Iwasaki, K. & Fujiwara, M., 7 9 2004, : : Behavioural Brain Research. 152, 2, p. 365-373 9 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Combination treatment of neonatal rats with hypoxia-ischemia and endotoxin induces long-lasting memory and learning impairment that is associated with extended cerebral damage

Ikeda, T., Mishima, K., Aoo, N., Egashira, N., Iwasaki, K., Fujiwara, M. & Ikenoue, T., 12 1 2004, : : American Journal of Obstetrics and Gynecology. 191, 6, p. 2132-2141 10 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Comparison of the effect of TAK-147 (zanapezil) and E-2020 (donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats

Hatip-Al-Khatib, I., Takashi, A., Egashira, N., Iwasaki, K. & Fujiwara, M., 6 25 2004, : : Brain Research. 1012, 1-2, p. 169-176 8 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

Determination of the effectiveness of components of the herbal medicine Toki-Shakuyaku-San and fractions of Angelica acutiloba in improving the scopolamine-induced impairment of rat's spatial cognition in eight-armed radial maze test

Hatip-Al-Khatib, I., Egashira, N., Mishima, K., Iwasaki, K., Iwasaki, K., Kurauchi, K., Inui, K., Ikeda, T. & Fujiwara, M., 9 1 2004, : : Journal of Pharmacological Sciences. 96, 1, p. 33-41 9 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Effects of hypothermia and hyperthermia on attentional and spatial learning deficits following neonatal hypoxia-ischemic insult in rats

Mishima, K., Ikeda, T., Yoshikawa, T., Aoo, N., Egashira, N., Xia, Y. X., Ikenoue, T., Iwasaki, K. & Fujiwara, M., 5 5 2004, : : Behavioural Brain Research. 151, 1-2, p. 209-217 9 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Inhibition of poly (ADP-ribose) polymerase and caspase-3, but not caspase-1, prevents apoptosis and improves spatial memory of rats with twice-repeated cerebral ischemia

Hatip-Al-Khatib, I., Iwasaki, K., Chung, E. H., Egashira, N., Mishima, K. & Fujiwara, M., 9 3 2004, : : Life Sciences. 75, 16, p. 1967-1978 12 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

Neuroprotective effect of γ-glutamylethylamide (theanine) on cerebral infarction in mice

Egashira, N., Hayakawa, K., Mishima, K., Kimura, H., Iwasaki, K. & Fujiwara, M., 6 3 2004, : : Neuroscience Letters. 363, 1, p. 58-61 4 p.

研究成果: ジャーナルへの寄稿記事

73 引用 (Scopus)

Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats

Iwasaki, K., Chung, E. H., Egashira, N., Hatip-Al-Khatib, I., Mishima, K., Egawa, T., Irie, K. & Fujiwara, M., 1 2 2004, : : Brain Research. 995, 1, p. 131-139 9 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)

Ovariectomy combined with amyloid β1-42 impairs memory by decreasing acetylcholine release and α7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats

Iwasaki, K., Hatip-Al-Khatib, I., Egashira, N., Akiyoshi, Y., Arai, T., Mishima, K., Takagaki, Y., Inui, K. & Fujiwara, M., 12 1 2004, : : Neurotoxicity Research. 6, 4, p. 299-309 11 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Protection by buckwheat polyphenols of cell death induced by glutamate and kainate in cultured hippocampal neurons

Fengling, P., Mishima, K., Irie, K., Egashira, N., Iwasaki, K., Fujiwara, M., Ikeda, T., Fujii, H. & Kosuna, K., 1 1 2004, : : Journal of Traditional Medicines. 21, 3, p. 143-146 4 p.

研究成果: ジャーナルへの寄稿記事

Protective Effect of Buckwheat Polyphenols Against Long-Lasting Impairment of Spatial Memory Associated with Hippocampal Neuronal Damage in Rats Subjected to Repeated Cerebral Ischemia

Pu, F., Mishima, K., Egashira, N., Iwasaki, K., Kaneko, T., Uchida, T., Irie, K., Ishibashi, D., Fujii, H., Kosuna, K. & Fujiwara, M., 4 1 2004, : : Journal of Pharmacological Sciences. 94, 4, p. 393-402 10 p.

研究成果: ジャーナルへの寄稿記事

46 引用 (Scopus)

The serotonin1A receptor agonist 8-OHDPAT reverses Δ9-tetrahydrocannabinol-induced impairment of spatial memory and reduction of acetylcholine release in the dorsal hippocampus in rats

Inui, K., Egashira, N., Mishima, K., Yano, A., Matsumoto, Y., Hasebe, N., Abe, K., Hayakawa, K., Ikeda, T., Iwasaki, K. & Fujiwara, M., 12 1 2004, : : Neurotoxicity Research. 6, 2, p. 153-157 5 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial maze

Egashira, N., Tanoue, A., Higashihara, F., Mishima, K., Fukue, Y., Takano, Y., Tsujimoto, G., Iwasaki, K. & Fujiwara, M., 2 19 2004, : : Neuroscience Letters. 356, 3, p. 195-198 4 p.

研究成果: ジャーナルへの寄稿記事

58 引用 (Scopus)
2003

Ameliorative effect of NC-1900, a new AVP4-9 analog, through vasopressin V1A receptor on scopolamine-induced impairments of spatial memory in the eight-arm radial maze

Mishima, K., Tsukikawa, H., Miura, I., Inada, K., Abe, K., Matsumoto, Y., Egashira, N., Iwasaki, K. & Fujiwara, M., 3 2003, : : Neuropharmacology. 44, 4, p. 541-552 12 p.

研究成果: ジャーナルへの寄稿記事

37 引用 (Scopus)

Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats

Iwasaki, K., Mishima, K., Egashira, N., Al-Khatib, I. H., Ishibashi, D., Irie, K., Kobayashi, H., Egawa, T. & Fujiwara, M., 10 1 2003, : : Journal of Pharmacological Sciences. 93, 2, p. 188-196 9 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)
8 引用 (Scopus)

Vitamin E isoforms α-tocotrienol and γ-tocopherol prevent cerebral infarction in mice

Mishima, K., Tanaka, T., Pu, F., Egashira, N., Iwasaki, K., Hidaka, R., Matsunaga, K., Takata, J., Karube, Y. & Fujiwara, M., 1 30 2003, : : Neuroscience Letters. 337, 1, p. 56-60 5 p.

研究成果: ジャーナルへの寄稿記事

81 引用 (Scopus)
2002

Hypoxia enhances β-amyloid-induced apoptosis in rat cultured hippocampal neurons

Egashira, N., Iwasaki, K., Ishibashi, M., Hatip-Al-Khatib, I., Wolozin, B., Mishima, K., Irie, K. & Fujiwara, M., 12 1 2002, : : Japanese Journal of Pharmacology. 90, 4, p. 321-327 7 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Impairment of spatial memory in kaolin-induced hydrocephalic rats is associated with changes in the hippocampal cholinergic and noradrenergic contents

Egawa, T., Mishima, K., Egashira, N., Fukuzawa, M., Abe, K., Yae, T., Iwasaki, K. & Fujiwara, M., 2 1 2002, : : Behavioural Brain Research. 129, 1-2, p. 31-39 9 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)

Intracerebral microinjections of Δ9-tetrahydrocannabinol: Search for the impairment of spatial memory in the eight-arm radial maze in rats

Egashira, N., Mishima, K., Iwasaki, K. & Fujiwara, M., 10 18 2002, : : Brain Research. 952, 2, p. 239-245 7 p.

研究成果: ジャーナルへの寄稿記事

72 引用 (Scopus)

Involvement of 5-hydroxytryptamine neuronal system in Δ9-tetrahydrocannabinol-induced impairment of spatial memory

Egashira, N., Mishima, K., Katsurabayashi, S., Yoshitake, T., Matsumoto, Y., Ishida, J., Yamaguchi, M., Iwasaki, K. & Fujiwara, M., 6 12 2002, : : European Journal of Pharmacology. 445, 3, p. 221-229 9 p.

研究成果: ジャーナルへの寄稿記事

57 引用 (Scopus)

Involvement of bcl-family expression in the spatial memory impairment induced by repeated ischemia

Irie, K., Mishima, K., Ishibashi, D., Egashira, N., Iwasaki, K. & Fujiwara, M., 12 20 2002, : : Life Sciences. 72, 4-5, p. 621-629 9 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)