• 2358 引用
  • 25 h指数
19992019

Research output per year

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
記事
2019

Effects of insulin signaling on mouse taste cell proliferation

Takai, S., Watanabe, Y., Sanematsu, K., Yoshida, R., Margolskee, R. F., Jiang, P., Atsuta, I., Koyano, K., Ninomiya, Y. & Shigemura, N., 1 1 2019, : : PloS one. 14, 11, e0225190.

研究成果: ジャーナルへの寄稿記事

公開

Expression of Renin-Angiotensin System Components in the Taste Organ of Mice

Shigemura, N., Takai, S., Hirose, F., Yoshida, R., Sanematsu, K. & Ninomiya, Y., 9 19 2019, : : Nutrients. 11, 9

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits

Park, J., Selvam, B., Sanematsu, K., Shigemura, N., Shukla, D. & Procko, E., 1 1 2019, : : Journal of Biological Chemistry. 294, 13, p. 4759-4774 16 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)
2018

Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae

Yoshida, R., Takai, S., Sanematsu, K., Margolskee, R. F., Shigemura, N. & Ninomiya, Y., 1 15 2018, : : Neuroscience. 369, p. 29-39 11 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Diurnal variation of sweet taste recognition thresholds is absent in overweight and obese humans

Sanematsu, K., Nakamura, Y., Nomura, M., Shigemura, N. & Ninomiya, Y., 3 2 2018, : : Nutrients. 10, 3, 297.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)
2017

The role of cholecystokinin in peripheral taste signaling in mice

Yoshida, R., Shin, M., Yasumatsu, K., Takai, S., Inoue, M., Shigemura, N., Takiguchi, S., Nakamura, S. & Ninomiya, Y., 10 31 2017, : : Frontiers in Physiology. 8, OCT, 866.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)
2016

Intracellular acidification is required for full activation of the sweet taste receptor by miraculin

Sanematsu, K., Kitagawa, M., Yoshida, R., Nirasawa, S., Shigemura, N. & Ninomiya, Y., 3 10 2016, : : Scientific reports. 6, 22807.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Leptin suppresses sweet taste responses of enteroendocrine STC-1 cells

Jyotaki, M., Sanematsu, K., Shigemura, N., Yoshida, R. & Ninomiya, Y., 9 22 2016, : : Neuroscience. 332, p. 76-87 12 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides

Sukumarana, S. K., Yeea, K. K., Iwatab, S., Kothaa, R., Quezada-Calvillo, R., Nichols, B. L., Mohan, S., Pinto, B. M., Shigemura, N., Ninomiya, Y. & Margolskee, R. F., 5 24 2016, : : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 6035-6040 6 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)
2015

Glucagon-like peptide-1 is specifically involved in sweet taste transmission

Takai, S., Yasumatsu, K., Inoue, M., Iwata, S., Yoshida, R., Shigemura, N., Yanagawa, Y., Drucker, D. J., Margolskee, R. F. & Ninomiya, Y., 6 1 2015, : : FASEB Journal. 29, 6, p. 2268-2280 13 p.

研究成果: ジャーナルへの寄稿記事

29 引用 (Scopus)

Leptin suppresses mouse taste cell responses to sweet compounds

Yoshida, R., Noguchi, K., Shigemura, N., Jyotaki, M., Takahashi, I., Margolskee, R. F. & Ninomiya, Y., 11 2015, : : Diabetes. 64, 11, p. 3751-3762 12 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice

Niki, M., Jyotaki, M., Yoshida, R., Yasumatsu, K., Shigemura, N., DiPatrizio, N. V., Piomelli, D. & Ninomiya, Y., 6 1 2015, : : Journal of Physiology. 593, 11, p. 2527-2545 19 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)
2014

Molecular mechanisms for sweet-suppressing effect of gymnemic acids

Sanematsu, K., Kusakabe, Y., Shigemura, N., Hirokawa, T., Nakamura, S., Imoto, T. & Ninomiya, Y., 9 12 2014, : : Journal of Biological Chemistry. 289, 37, p. 25711-25720 10 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

Structure, function, and signaling of taste g-protein-coupled receptors

Sanematsu, K., Yoshida, R., Shigemura, N. & Ninomiya, Y., 1 1 2014, : : Current Pharmaceutical Biotechnology. 15, 10, p. 951-961 11 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)
2013

Angiotensin II modulates salty and sweet taste sensitivities

Shigemura, N., Iwata, S., Yasumatsu, K., Ohkuri, T., Horio, N., Sanematsu, K., Yoshida, R., Margolskee, R. F. & Ninomiya, Y., 4 10 2013, : : Journal of Neuroscience. 33, 15, p. 6267-6277 11 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)
2010

Endocannabinoids selectively enhance sweet taste

Yoshida, R., Ohkuri, T., Jyotaki, M., Yasuo, T., Horio, N., Yasumatsu, K., Sanematsu, K., Shigemura, N., Yamamoto, T., Margolskee, R. F. & Ninomiya, Y., 2 15 2010, : : Proceedings of the National Academy of Sciences of the United States of America. 107, 2, p. 935-939 5 p.

研究成果: ジャーナルへの寄稿記事

128 引用 (Scopus)

Taste preference for fatty acids is mediated by GPR40 and GPR120

Cartoni, C., Yasumatsu, K., Ohkuri, T., Shigemura, N., Yoshida, R., Godinot, N., Le Coutre, J., Ninomiya, Y. & Damak, S., 6 23 2010, : : Journal of Neuroscience. 30, 25, p. 8376-8382 7 p.

研究成果: ジャーナルへの寄稿記事

252 引用 (Scopus)
2009

Discrimination of taste qualities among mouse fungiform taste bud cells

Yoshida, R., Miyauchi, A., Yasuo, T., Jyotaki, M., Murata, Y., Yasumatsu, K., Shigemura, N., Yanagawa, Y., Obata, K., Ueno, H., Margolskee, R. F. & Ninomiya, Y., 9 1 2009, : : Journal of Physiology. 587, 18, p. 4425-4439 15 p.

研究成果: ジャーナルへの寄稿記事

63 引用 (Scopus)

Genetically-increased taste cell population with Gα-gustducin-coupled sweet receptors is associated with increase of gurmarin-sensitive taste nerve fibers in mice

Nakano, K., Ohkuri, T., Sanematsu, K., Shigemura, N., Katsukawa, H., Sako, N. & Ninomiya, Y., 12 22 2009, : : BMC Neuroscience. 10, 152.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Genetic and molecular basis of individual differences in human umami taste perception

Shigemura, N., Shirosaki, S., Sanematsu, K., Yoshida, R. & Ninomiya, Y., 8 21 2009, : : PloS one. 4, 8, e6717.

研究成果: ジャーナルへの寄稿記事

60 引用 (Scopus)

NaCl responsive taste cells in the mouse fungiform taste buds

Yoshida, R., Horio, N., Murata, Y., Nakano, K., Shigemura, N. & Ninomiya, Y., 3 17 2009, : : Neuroscience. 159, 2, p. 795-803 9 p.

研究成果: ジャーナルへの寄稿記事

55 引用 (Scopus)

Sweet taste receptor expressed in pancreatic β-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

Nakagawa, Y., Nagasawa, M., Yamada, S., Hara, A., Mogami, H., Nikolaev, V. O., Lohse, M. J., Shigemura, N., Ninomiya, Y. & Kojima, I., 4 8 2009, : : PloS one. 4, 4, e5106.

研究成果: ジャーナルへの寄稿記事

184 引用 (Scopus)

Variation in umami perception and in candidate genes for the umami receptor in mice and humans

Shigemura, N., Shirosaki, S., Ohkuri, T., Sanematsu, K., Islam, A. A. S., Ogiwara, Y., Kawai, M., Yoshida, R. & Ninomiya, Y., 9 1 2009, : : American Journal of Clinical Nutrition. 90, 3, p. 764S-769S

研究成果: ジャーナルへの寄稿記事

51 引用 (Scopus)
2008

Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC α-subunit in mice

Shigemura, N., Ohkuri, T., Sadamitsu, C., Yasumatsu, K., Yoshida, R., Beauchamp, G. K., Bachmanov, A. A. & Ninomiya, Y., 1 1 2008, : : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 1, p. R66-R75

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)

Diurnal variation of human sweet taste recognition thresholds is correlated with plasma leptin levels

Nakamura, Y., Sanematsu, K., Ohta, R., Shirosaki, S., Koyano, K., Nonaka, K., Shigemura, N. & Ninomiya, Y., 10 1 2008, : : Diabetes. 57, 10, p. 2661-2665 5 p.

研究成果: ジャーナルへの寄稿記事

88 引用 (Scopus)

Gurmarin sensitivity of sweet taste responses is associated with co-expression patterns of T1r2, T1r3, and gustducin

Shigemura, N., Nakao, K., Yasuo, T., Murata, Y., Yasumatsu, K., Nakashima, A., Katsukawa, H., Sako, N. & Ninomiya, Y., 3 7 2008, : : Biochemical and Biophysical Research Communications. 367, 2, p. 356-363 8 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)
2007

Recovery of two independent sweet taste systems during regeneration of the mouse chorda tympani nerve after nerve crush

Nakano, K., Kusuhara, Y., Shigemura, N. & Ninomiya, Y., 9 1 2007, : : European Journal of Neuroscience. 26, 6, p. 1521-1529 9 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)
2006

Amiloride inhibition on NaCl responses of the chorda tympani nerve in two 129 substrains of mice, 129P3/J and 129X1/SvJ

Ohkuri, T., Yasumatsu, K., Shigemura, N., Yoshida, R. & Ninomiya, Y., 7 1 2006, : : Chemical Senses. 31, 6, p. 565-572 8 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Taste responsiveness of fungiform taste cells with action potentials

Yoshida, R., Shigemura, N., Sanematsu, K., Yasumatsu, K., Ishizuka, S. & Ninomiya, Y., 12 1 2006, : : Journal of Neurophysiology. 96, 6, p. 3088-3095 8 p.

研究成果: ジャーナルへの寄稿記事

62 引用 (Scopus)

Trpm5 null mice respond to bitter, sweet, and umami compounds

Damak, S., Rong, M., Yasumatsu, K., Kokrashvili, Z., Pérez, C. A., Shigemura, N., Yoshida, R., Mosinger, B., Glendinning, J. I., Ninomiya, Y. & Margolskee, R. F., 3 1 2006, : : Chemical Senses. 31, 3, p. 253-264 12 p.

研究成果: ジャーナルへの寄稿記事

222 引用 (Scopus)
2005

Expression of amiloride-sensitive epithelial sodium channels in mouse taste cells after chorda tympani nerve crush

Shigemura, N., Islam, A. A. S., Sadamitsu, C., Yoshida, R., Yasumatsu, K. & Ninomiya, Y., 7 1 2005, : : Chemical Senses. 30, 6, p. 531-538 8 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Heat activation of TRPM5 underlies thermal sensitivity of sweet taste

Talavera, K., Yasumatsu, K., Voets, T., Droogmans, G., Shigemura, N., Ninomiya, Y., Margolskee, R. F. & Nilius, B., 12 15 2005, : : Nature. 438, 7070, p. 1022-1025 4 p.

研究成果: ジャーナルへの寄稿記事

306 引用 (Scopus)

Mouse strain differences in Gurmarin-sensitivity of sweet taste responses are not associated with polymorphisms of the sweet receptor gene, Tas1r3

Sanematsu, K., Yasumatsu, K., Yoshida, R., Shigemura, N. & Ninomiya, Y., 7 1 2005, : : Chemical Senses. 30, 6, p. 491-496 6 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Recovery of salt taste responses and PGP 9.5 immunoreactive taste bud cells during regeneration of the mouse chorda tympani nerve

Yasumatsu, K., Shigemura, N., Yoshida, R. & Ninomiya, Y., 1 1 2005, : : Chemical Senses. 30 SUPPL. 1, p. i62-i63

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Taste receptor cells responding with action potentials to taste stimuli and their molecular expression of taste related genes

Yoshida, R., Sanematsu, K., Shigemura, N., Yasumatsu, K. & Ninomiya, Y., 1 1 2005, : : Chemical Senses. 30 SUPPL. 1, p. i19-i20

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

The role of the dpa Locus in Mice

Shigemura, N., Yasumatsu, K., Yoshida, R., Sako, N., Katsukawa, H., Nakashima, K., Imoto, T. & Ninomiya, Y., 1 1 2005, : : Chemical Senses. 30 SUPPL. 1, p. i84-i85

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)
2004

Leptin Modulates Behavioral Responses to Sweet Substances by Influencing Peripheral Taste Structures

Shigemura, N., Ohta, R., Kusakabe, Y., Miura, H., Hino, A., Koyano, K., Nakashima, K. & Ninomiya, Y., 2 1 2004, : : Endocrinology. 145, 2, p. 839-847 9 p.

研究成果: ジャーナルへの寄稿記事

140 引用 (Scopus)
2003

Conditioned taste aversion learning in leptin-receptor-deficient db/db mice

Ohta, R., Shigemura, N., Sasamoto, K., Koyano, K. & Ninomiya, Y., 9 2003, : : Neurobiology of Learning and Memory. 80, 2, p. 105-112 8 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Expression of leptin receptor (Ob-R) isoforms and signal transducers and activators of transcription (STATs) mRNAs in the mouse taste buds

Shigemura, N., Miura, H., Kusakabe, Y., Hino, A. & Ninomiya, Y., 8 1 2003, : : Archives of Histology and Cytology. 66, 3, p. 253-260 8 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)

Gurmarin suppression of licking responses to sweetener-quinine mixtures in C57BL mice

Murata, Y., Nakashima, K., Yamada, A., Shigemura, N., Sasamoto, K. & Ninomiya, Y., 3 1 2003, : : Chemical Senses. 28, 3, p. 237-243 7 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)
2002

Ion channels and second messengers involved in transduction and modulation of sweet taste in mouse taste cells

Sugimoto, K., Shigemura, N., Yasumatsu, K., Ohta, R., Nakashima, K., Kawai, K. & Ninomiya, Y., 7 1 2002, : : Pure and Applied Chemistry. 74, 7, p. 1141-1151 11 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)
2001

Detection of differentially expressed genes in the early developmental stage of the mouse mandible

Yamaza, H., Matsuo, K., Kiyoshima, T., Shigemura, N., Kobayashi, I., Wada, H., Akamime, A. & Sakai, H., 8 2 2001, : : International Journal of Developmental Biology. 45, 4, p. 675-680 6 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Localization of activated caspase-3-positive and apoptotic cells in the developing tooth germ of the mouse lower first molar

Shigemura, N., Kiyoshima, T., Sakai, T., Matsuo, K., Momoi, T., Yamaza, H., Kobayashi, I., Wada, H., Akamine, A. & Sakai, H., 1 1 2001, : : Histochemical Journal. 33, 5, p. 253-258 6 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)
1999

Immunohistochemical and ultrastructural study of a papillary cystadenocarcinoma arising from the sublingual gland

Kobayashi, I., Kiyoshima, T., Ozeki, S., Shima, K., Shigemura, N., Matsuo, K. & Sakai, H., 7 1 1999, : : Journal of Oral Pathology and Medicine. 28, 6, p. 282-286 5 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

The distribution of BrdU- and TUNEL-positive cells during odontogenesis in mouse lower first molars

Shigemura, N., Kiyoshima, T., Kobayashi, I., Matsuo, K., Yamaza, H., Akamine, A. & Sakai, H., 8 11 1999, : : Histochemical Journal. 31, 6, p. 367-377 11 p.

研究成果: ジャーナルへの寄稿記事

48 引用 (Scopus)