Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2018

2018
5 引用 (Scopus)

Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity

Lee, S. A., Jang, S. H., Kim, B. H., Shibata, T., Yoo, J., Jung, Y., Kawabata, S-I. & Lee, B. L., 4 1 2018, : : Developmental and Comparative Immunology. 81, p. 116-126 11 p.

研究成果: ジャーナルへの寄稿記事

Metalloproteases
Humoral Immunity
Cellular Immunity
Insects
Innate Immunity
1 引用 (Scopus)
Enzyme Precursors
Serine Proteases
Lipopolysaccharides
Chemical activation
Molecules
2 引用 (Scopus)

Pluripotency and a secretion mechanism of Drosophila transglutaminase

Shibata, T. & Kawabata, S-I., 3 1 2018, : : Journal of biochemistry. 163, 3, p. 165-176 12 p.

研究成果: ジャーナルへの寄稿評論記事

Transglutaminases
Drosophila
Glutamine
Exosomes
Acylation
2017
7 引用 (Scopus)

Drosophila TG-A transglutaminase is secreted via an unconventional Golgi-independent mechanism involving exosomes and two types of fatty acylations

Shibata, T., Hadano, J., Kawasaki, D., Dong, X., Kawabata, S-I. & Sllner, T., 1 1 2017, : : Journal of Biological Chemistry. 292, 25, p. 10723-10734 12 p.

研究成果: ジャーナルへの寄稿記事

Exosomes
Acylation
Transglutaminases
Drosophila
Lipoylation
2 引用 (Scopus)

Genetic engineering approach to develop next-generation reagents for endotoxin quantification

Mizumura, H., Ogura, N., Aketagawa, J., Aizawa, M., Kobayashi, Y., Kawabata, S-I. & Oda, T., 1 1 2017, : : Innate Immunity. 23, 2, p. 136-146 11 p.

研究成果: ジャーナルへの寄稿記事

Genetic Engineering
Endotoxins
Horseshoe Crabs
Insects
Peptide Hydrolases
2 引用 (Scopus)
Takifugu
Saxitoxin
Tetraodontiformes
Tetrodotoxin
Denaturation
3 引用 (Scopus)
Transglutaminases
Polyamines
Masks
Transcription Factors
DNA
2016
4 引用 (Scopus)

RNA interference directed against the Transglutaminase gene triggers dysbiosis of gut microbiota in Drosophila

Sekihara, S., Shibata, T., Hyakkendani, M. & Kawabata, S-I., 11 25 2016, : : Journal of Biological Chemistry. 291, 48, p. 25077-25087 11 p.

研究成果: ジャーナルへの寄稿記事

Dysbiosis
Transglutaminases
Acetobacter
RNA Interference
Diptera
5 引用 (Scopus)

Transglutaminase in Invertebrates

Shibata, T. & Kawabata, S-I., 1 1 2016, Transglutaminases: Multiple Functional Modifiers and Targets for New Drug Discovery. Springer Japan, p. 117-127 11 p.

研究成果: 著書/レポートタイプへの貢献

Transglutaminases
Invertebrates
Horseshoe Crabs
Antigen-antibody reactions
Genetic Techniques
2015
14 引用 (Scopus)

Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins

Shibata, T., Maki, K., Hadano, J., Fujikawa, T., Kitazaki, K., Koshiba, T. & Kawabata, S-I., 1 1 2015, : : PLoS Pathogens. 11, 10, e1005244.

研究成果: ジャーナルへの寄稿記事

Exotoxins
Transglutaminases
Epithelium
Diptera
Proteins
3 引用 (Scopus)

Factor B is the second lipopolysaccharide-binding protease zymogen in the horseshoe crab coagulation cascade

Kobayashi, Y., Takahashi, T., Shibata, T., Ikeda, S., Koshiba, T., Mizumura, H., Oda, T. & Kawabata, S-I., 7 31 2015, : : Journal of Biological Chemistry. 290, 31, p. 19379-19386 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Enzyme Precursors
Complement Factor B
Coagulation
Lipopolysaccharides

First Asian Invertebrate Immunity Symposium (Busan, Korea). Preface to the Special Issue

Lee, B. L. U., Kawabata, S-I., Wang, C. & Kim, Y., 1 1 2015, : : Archives of insect biochemistry and physiology. 88, 1, p. 1-3 3 p.

研究成果: ジャーナルへの寄稿編集

Animals
Cytokines
Invertebrates
2014
65 引用 (Scopus)

Influenza a virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

Yoshizumi, T., Ichinohe, T., Sasaki, O., Otera, H., Kawabata, S-I., Mihara, K. & Koshiba, T., 8 20 2014, : : Nature communications. 5, 4713.

研究成果: ジャーナルへの寄稿記事

influenza
Mitochondria
mitochondria
immunity
viruses
37 引用 (Scopus)

Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide

Kushibiki, T., Kamiya, M., Aizawa, T., Kumaki, Y., Kikukawa, T., Mizuguchi, M., Demura, M., Kawabata, S-I. & Kawano, K., 3 1 2014, : : Biochimica et Biophysica Acta - Proteins and Proteomics. 1844, 3, p. 527-534 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lipopolysaccharides
Peptides
Tryptophan
Fluorescence
8 引用 (Scopus)

The N-terminal Arg residue is essential for autocatalytic activation of a lipopolysaccharide-responsive protease zymogen

Kobayashi, Y., Shiga, T., Shibata, T., Sako, M., Maenaka, K., Koshiba, T., Mizumura, H., Oda, T. & Kawabata, S-I., 9 12 2014, : : Journal of Biological Chemistry. 289, 37, p. 25987-25995 9 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Lipopolysaccharides
Peptide Hydrolases
Chemical activation
Molecules
2013
13 引用 (Scopus)

A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer

Sasaki, O., Yoshizumi, T., Kuboyama, M., Ishihara, T., Suzuki, E., Kawabata, S-I. & Koshiba, T., 5 1 2013, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 5, p. 1017-1027 11 p.

研究成果: ジャーナルへの寄稿記事

Energy Transfer
Mitochondrial Membranes
Antiviral Agents
RNA Virus Infections
Mitochondria
4 引用 (Scopus)

Expression and functional characterization of recombinant tributyltin-binding protein type 2

Satone, H., Akahoshi, E., Nakamura, A., Lee, M., Honda, M., Shimasaki, Y., Kawabata, S-I., Kusakabe, T. & Oshima, Y., 11 18 2013, : : Journal of Toxicological Sciences. 38, 6, p. 885-890 6 p.

研究成果: ジャーナルへの寄稿レター

Lipocalins
Carrier Proteins
Bombyx
Baculoviridae
Fish

Limulus Clotting Enzyme

Kawabata, S-I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3064-3066 3 p.

研究成果: 著書/レポートタイプへの貢献

Horseshoe Crabs
clotting enzyme

Limulus Coagulation Factor B

Kawabata, S-I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3063-3064 2 p.

研究成果: 著書/レポートタイプへの貢献

Horseshoe Crabs
Blood Coagulation Factors

Limulus Coagulation Factor C

Kawabata, S-I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3060-3063 4 p.

研究成果: 著書/レポートタイプへの貢献

Blood Coagulation Factors
Limulus clotting factor C

Limulus Coagulation Factor G

Kawabata, S-I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3066-3067 2 p.

研究成果: 著書/レポートタイプへの貢献

Horseshoe Crabs
Blood Coagulation Factors

Limulus Kexin

Kawabata, S-I. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3277-3278 2 p.

研究成果: 著書/レポートタイプへの貢献

Horseshoe Crabs
25 引用 (Scopus)

Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish

Shibata, T., Sekihara, S., Fujikawa, T., Miyaji, R., Maki, K., Ishihara, T., Koshiba, T. & Kawabata, S-I., 7 23 2013, : : Science Signaling. 6, 285, ra61.

研究成果: ジャーナルへの寄稿記事

Transglutaminases
Transcription Factors
Diptera
RNA Interference
Proteins

Trimerelysin I

Kawabata, S-I. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 1. p. 1044-1046 3 p.

研究成果: 著書/レポートタイプへの貢献

Trimerelysin II

Kawabata, S-I. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 1. p. 1046-1047 2 p.

研究成果: 著書/レポートタイプへの貢献

2012
13 引用 (Scopus)

Microbe-specific C3b deposition in the horseshoe crab complement system in a C2/factor B-dependent or -independent manner

Tagawa, K., Yoshihara, T., Shibata, T., Kitazaki, K., Endo, Y., Fujita, T., Koshiba, T. & Kawabata, S-I., 5 7 2012, : : PloS one. 7, 5, e36783.

研究成果: ジャーナルへの寄稿記事

Merostomata
Horseshoe Crabs
Complement Factor B
Lectins
lectins
2011
18 引用 (Scopus)

Mitochondria and antiviral innate immunity

Koshiba, T., Bashiruddin, N. & Kawabata, S-I., 2011, : : International Journal of Biochemistry and Molecular Biology. 2, 3, p. 257-262 6 p.

研究成果: ジャーナルへの寄稿評論記事

Mitochondria
Innate Immunity
Antiviral Agents
Immunity
Signal transduction
110 引用 (Scopus)

Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling

Koshiba, T., Yasukawa, K., Yanagi, Y. & Kawabata, S-I., 2 1 2011, : : Science Signaling. 4, 158, ra7.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Membrane Potential
Antiviral Agents
Membranes
Mitochondria
Innate Immunity
30 引用 (Scopus)

Peptidoglycan activation of the proPO-system without a peptidoglycan receptor protein (PGRP)?

Liu, H., Wu, C., Matsuda, Y., Kawabata, S-I., Lee, B. L., Söderhäll, K. & Söderhäll, I., 1 1 2011, : : Developmental and Comparative Immunology. 35, 1, p. 51-61 11 p.

研究成果: ジャーナルへの寄稿記事

Peptidoglycan
Lysine
Lipopolysaccharides
Astacoidea
Proteins
8 引用 (Scopus)

Purification and characterization of tributyltin-binding protein of tiger puffer, Takifugu rubripes

Oba, Y., Yamauchi, A., Hashiguchi, Y., Satone, H., Miki, S., Nassef, M., Shimasaki, Y., Kitano, T., Nakao, M., Kawabata, S-I., Honjo, T. & Oshima, Y., 1 1 2011, : : Comparative Biochemistry and Physiology - C Toxicology and Pharmacology. 153, 1, p. 17-23 7 p.

研究成果: ジャーナルへの寄稿記事

Takifugu
Tetraodontiformes
Purification
Carrier Proteins
Electrophoresis
22 引用 (Scopus)

Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: Implications for mitochondrial inheritance

Koshiba, T., Holman, H. A., Kubara, K., Yasukawa, K., Kawabata, S-I., Okamoto, K., Macfarlane, J. & Shaw, J. M., 1 7 2011, : : Journal of Biological Chemistry. 286, 1, p. 354-362 9 p.

研究成果: ジャーナルへの寄稿記事

rho GTP-Binding Proteins
Mitochondrial Genes
GTP Phosphohydrolases
EF Hand Motifs
Yeast
8 引用 (Scopus)

Tributyltin-binding protein type 1, a lipocalin, prevents inhibition of osteoblastic activity by tributyltin in fish scales

Satone, H., Lee, M., Oba, Y., Kusakabe, T., Akahoshi, E., Miki, S., Suzuki, N., Sasayama, Y., Nassef, M., Shimasaki, Y., Kawabata, S-I., Honjo, T. & Oshima, Y., 5 1 2011, : : Aquatic Toxicology. 103, 1-2, p. 79-84 6 p.

研究成果: ジャーナルへの寄稿記事

Lipocalin 1
tributyltin
binding proteins
Carrier Proteins
Fishes
2010
26 引用 (Scopus)

Immunocompetent molecules and their response network in horseshoe crabs

Kawabata, S-I., 12 1 2010, Invertebrate Immunity. p. 122-136 15 p. (Advances in Experimental Medicine and Biology; 巻数 708).

研究成果: 著書/レポートタイプへの貢献

Horseshoe Crabs
Lipopolysaccharides
Hemocytes
Molecules
Transglutaminases
30 引用 (Scopus)

Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila

Shibata, T., Ariki, S., Shinzawa, N., Miyaji, R., Suyama, H., Sako, M., Inomata, N., Koshiba, T., Kanuka, H. & Kawabata, S-I., 11 17 2010, : : PloS one. 5, 10, e13477.

研究成果: ジャーナルへの寄稿記事

Transglutaminases
protein-glutamine gamma-glutamyltransferase
crosslinking
Morphogenesis
Crosslinking
191 引用 (Scopus)

Proteolytic cascades and their involvement in invertebrate immunity

Cerenius, L., Kawabata, S-I., Lee, B. L., Nonaka, M. & Söderhäll, K., 10 1 2010, : : Trends in Biochemical Sciences. 35, 10, p. 575-583 9 p.

研究成果: ジャーナルへの寄稿評論記事

Invertebrates
Immunity
Complement Receptors
Immune system
Toll-Like Receptors
19 引用 (Scopus)
Hemocytes
Glucans
Hemolymph
Invertebrates
Coagulation
2009
10 引用 (Scopus)

A novel β-defensin structure: Big defensin changes its N-terminal structure to associate with the target membrane

Kouno, T., Mizuguchi, M., Aizawa, T., Shinoda, H., Demura, M., Kawabata, S-I. & Kawano, K., 8 18 2009, : : Biochemistry. 48, 32, p. 7629-7635 7 p.

研究成果: ジャーナルへの寄稿記事

Defensins
Membranes
Micelles
Nuclear magnetic resonance
Horseshoe Crabs
1 引用 (Scopus)

Biological and immunological aspects of innate defence mechanisms activated by (1,3)----lucans and related polysaccharides in invertebrates

Cerenius, L., Kawabata, S-I. & Soöerhäll, K., 12 1 2009, Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides. Elsevier Inc., p. 563-577 15 p.

研究成果: 著書/レポートタイプへの貢献

Invertebrates
Polysaccharides
Antigen-antibody reactions
Oomycetes
Pathogens
45 引用 (Scopus)

Factor C acts as a lipopolysaccharide-responsive C3 convertase in horseshoe crab complement activation

Ariki, S., Takahara, S., Shibata, T., Fukuoka, T., Ozaki, A., Endo, Y., Fujita, T., Koshiba, T. & Kawabata, S-I., 12 1 2009, : : Journal of Immunology. 181, 11, p. 7994-8001 8 p.

研究成果: ジャーナルへの寄稿記事

Complement C3-C5 Convertases
Horseshoe Crabs
Complement Activation
Lipopolysaccharides
Gram-Negative Bacteria
6 引用 (Scopus)

Factor G utilizes a carbohydrate-binding cleft that is conserved between horseshoe crab and bacteria for the recognition of β-1,3-D-glucans

Ueda, Y., Ohwada, S., Abe, Y., Shibata, T., Iijima, M., Yoshimitsu, Y., Koshiba, T., Nakata, M., Ueda, T. & Kawabata, S-I., 9 15 2009, : : Journal of Immunology. 183, 6, p. 3810-3818 9 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Carbohydrates
Bacteria
Endo-1,4-beta Xylanases
Cellvibrio
140 引用 (Scopus)

Mitofusin 2 inhibits mitochondrial antiviral signaling

Yasukawa, K., Oshiumi, H., Takeda, M., Ishihara, N., Yanagi, Y., Seya, T., Kawabata, S-I. & Koshiba, T., 8 18 2009, : : Science Signaling. 2, 84

研究成果: ジャーナルへの寄稿記事

Antiviral Agents
Mitochondrial Dynamics
Genes
Chemical activation
Interferon Regulatory Factor-3
2008
24 引用 (Scopus)

A novel β-defensin structure: A potential strategy of big defensin for overcoming resistance by gram-positive bacteria

Kouno, T., Fujitani, N., Mizuguchi, M., Osaki, T., Nishimura, S. I., Kawabata, S-I., Aizawa, T., Demura, M., Nitta, K. & Kawano, K., 10 7 2008, : : Biochemistry. 47, 40, p. 10611-10619 9 p.

研究成果: ジャーナルへの寄稿記事

Defensins
Gram-Positive Bacteria
Bacteria
Micelles
Gram-Negative Bacteria
17 引用 (Scopus)

Tributyltin-binding protein type 1 has a distinctive lipocalin-like structure and is involved in the excretion of tributyltin in Japanese flounder, Paralichthys olivaceus

Satone, H., Oshima, Y., Shimasaki, Y., Tawaratsumida, T., Oba, Y., Takahashi, E., Kitano, T., Kawabata, S-I., Kakuta, Y. & Honjo, T., 12 11 2008, : : Aquatic Toxicology. 90, 4, p. 292-299 8 p.

研究成果: ジャーナルへの寄稿記事

Lipocalins
Flounder
Paralichthys olivaceus
tributyltin
excretion
2007
20 引用 (Scopus)

A cysteine-rich protein from an arthropod stabilizes clotting mesh and immobilizes bacteria at injury sites

Matsuda, Y., Osaki, T., Hashii, T., Koshiba, T. & Kawabata, S-I., 11 16 2007, : : Journal of Biological Chemistry. 282, 46, p. 33545-33552 8 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Hemocytes
Transglutaminases
Cysteine
Bacteria
17 引用 (Scopus)

An arthropod cuticular chitin-binding protein endows injured sites with transglutaminase-dependent mesh

Matsuda, Y., Koshiba, T., Osaki, T., Suyama, H., Arisaka, F., Toh, Y. & Kawabata, S-I., 12 28 2007, : : Journal of Biological Chemistry. 282, 52, p. 37316-37324 9 p.

研究成果: ジャーナルへの寄稿記事

Transglutaminases
Chitin
Arthropods
Carrier Proteins
Horseshoe Crabs
39 引用 (Scopus)
Gram-Negative Bacteria
Lipopolysaccharides
Bacteria
Innate Immunity
Horseshoe Crabs
30 引用 (Scopus)

Purification and characterization of tributyltin-binding protein type 2 from plasma of Japanese flounder, Paralichthys olivaceus

Oba, Y., Shimasaki, Y., Oshima, Y., Satone, H., Kitano, T., Nakao, M., Kawabata, S-I. & Honjo, T., 8 1 2007, : : Journal of biochemistry. 142, 2, p. 229-238 10 p.

研究成果: ジャーナルへの寄稿記事

Flounder
Purification
Carrier Proteins
Plasmas
Electrophoresis
142 引用 (Scopus)

Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERRγ

Matsushima, A., Kakuta, Y., Teramoto, T., Koshiba, T., Liu, X., Okada, H., Tokunaga, T., Kawabata, S-I., Kimura, M. & Shimohigashi, Y., 10 1 2007, : : Journal of biochemistry. 142, 4, p. 517-524 8 p.

研究成果: ジャーナルへの寄稿記事

Endocrine Disruptors
Cytoplasmic and Nuclear Receptors
Estrogen Receptors
Estrogens
Ligands
13 引用 (Scopus)

The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif

Fujitani, N., Kouno, T., Nakahara, T., Takaya, K., Osaki, T., Kawabata, S-I., Mizuguchi, M., Aizawa, T., Demura, M., Nishimura, S. I. & Kawano, K., 4 1 2007, : : Journal of Peptide Science. 13, 4, p. 269-279 11 p.

研究成果: ジャーナルへの寄稿記事

Cystine Knot Motifs
Horseshoe Crabs
Cystine
Chitin
Peptides