Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2018

32 引用 (Scopus)
Trimeresurus
Snake Venoms
Phospholipases
Phospholipases A2
Isoenzymes
31 引用 (Scopus)

Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking

Iijima, M., Hashimoto, T., Matsuda, Y., Nagai, T., Yamano, Y., Ichi, T., Osaki, T. & Kawabata, S. I., 9 1 2005, : : FEBS Journal. 272, 18, p. 4774-4786 13 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Transglutaminases
Chitin
Sequence Analysis
Molecular mass
15 引用 (Scopus)

Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins

Shibata, T., Maki, K., Hadano, J., Fujikawa, T., Kitazaki, K., Koshiba, T. & Kawabata, S. I., 1 1 2015, : : PLoS pathogens. 11, 10, e1005244.

研究成果: ジャーナルへの寄稿記事

Exotoxins
Transglutaminases
Epithelium
Diptera
Proteins
6 引用 (Scopus)

Difference in Enzymatic Properties between “Staphylothrombin” and Free α‐Thrombin

Kawabata, S-I., MORITA, TAKASHI., MIYATA, TOSHIYUKI., KAIDA, SHIGENORI., IGARASHI, HIDEO. & IWANAGA, SADAAKI., 1 1 1986, : : Annals of the New York Academy of Sciences. 485, 1, p. 27-40 14 p.

研究成果: ジャーナルへの寄稿記事

Prothrombin
Coagulase
Thrombin
amidase
Sequence Homology
25 引用 (Scopus)

Difference in enzymatic properties between α-thrombin-staphylocoagulase complex and free α-thrombin

Kawabata, S-I., Morita, T., Iwanaga, S. & Igarashi, H., 1 1 1985, : : Journal of Biochemistry. 97, 4, p. 1073-1078 6 p.

研究成果: ジャーナルへの寄稿記事

Coagulase
Thrombin
S 2238
amidase
Kinetic parameters
7 引用 (Scopus)

Drosophila TG-A transglutaminase is secreted via an unconventional Golgi-independent mechanism involving exosomes and two types of fatty acylations

Shibata, T., Hadano, J., Kawasaki, D., Dong, X., Kawabata, S. I. & Sllner, T., 1 1 2017, : : Journal of Biological Chemistry. 292, 25, p. 10723-10734 12 p.

研究成果: ジャーナルへの寄稿記事

Exosomes
Acylation
Transglutaminases
Drosophila
Lipoylation
43 引用 (Scopus)
Glucans
Innate Immunity
Pattern recognition
Binding Sites
Enzyme Precursors
52 引用 (Scopus)

Enzymatic properties of staphylothrombin, an active molecular complex formed between staphylocoagulase and human prothrombin

Kawabata, S. I., Morita, T., Iwanaga, S. & Igarashi, H., 12 1985, : : Journal of biochemistry. 98, 6, p. 1603-1614 12 p.

研究成果: ジャーナルへの寄稿記事

Coagulase
Prothrombin
Thrombin
Isoflurophate
Catalytic Domain
79 引用 (Scopus)
Horseshoe Crabs
Hemolymph
Agglutination
Phylogeny
Innate Immunity
4 引用 (Scopus)

Expression and functional characterization of recombinant tributyltin-binding protein type 2

Satone, H., Akahoshi, E., Nakamura, A., Lee, J. M., Honda, M., Shimasaki, Y., Kawabata, S. I., Kusakabe, T. & Oshima, Y., 11 18 2013, : : Journal of Toxicological Sciences. 38, 6, p. 885-890 6 p.

研究成果: ジャーナルへの寄稿レター

Lipocalins
Carrier Proteins
Bombyx
Baculoviridae
Fish
4 引用 (Scopus)

Factor B is the second lipopolysaccharide-binding protease zymogen in the horseshoe crab coagulation cascade

Kobayashi, Y., Takahashi, T., Shibata, T., Ikeda, S., Koshiba, T., Mizumura, H., Oda, T. & Kawabata, S. I., 7 31 2015, : : Journal of Biological Chemistry. 290, 31, p. 19379-19386 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Enzyme Precursors
Complement Factor B
Coagulation
Lipopolysaccharides
46 引用 (Scopus)

Factor C acts as a lipopolysaccharide-responsive C3 convertase in horseshoe crab complement activation

Ariki, S., Takahara, S., Shibata, T., Fukuoka, T., Ozaki, A., Endo, Y., Fujita, T., Koshiba, T. & Kawabata, S. I., 12 1 2009, : : Journal of Immunology. 181, 11, p. 7994-8001 8 p.

研究成果: ジャーナルへの寄稿記事

Complement C3-C5 Convertases
Horseshoe Crabs
Complement Activation
Lipopolysaccharides
Gram-Negative Bacteria
8 引用 (Scopus)

Factor G utilizes a carbohydrate-binding cleft that is conserved between horseshoe crab and bacteria for the recognition of β-1,3-D-glucans

Ueda, Y., Ohwada, S., Abe, Y., Shibata, T., Iijima, M., Yoshimitsu, Y., Koshiba, T., Nakata, M., Ueda, T. & Kawabata, S. I., 9 15 2009, : : Journal of Immunology. 183, 6, p. 3810-3818 9 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Carbohydrates
Bacteria
Endo-1,4-beta Xylanases
Cellvibrio
14 引用 (Scopus)

Factor IX Kawachinagano: impaired function of the Gla‐domain caused by attached propeptide region due to substitution of arginine by glutamine at position −4

Sugimoto, M., Miyata, T., Kawabata, S-I., Yoshioka, A., Fukui, H. & Iwanaga, S., 1 1 1989, : : British Journal of Haematology. 72, 2, p. 216-221 6 p.

研究成果: ジャーナルへの寄稿記事

Glutamine
Arginine
Factor XIa
Factor IX
Hemophilia B

First Asian Invertebrate Immunity Symposium (Busan, Korea). Preface to the Special Issue

Lee, B. L. U., Kawabata, S. I., Wang, C. & Kim, Y., 1 1 2015, : : Archives of insect biochemistry and physiology. 88, 1, p. 1-3 3 p.

研究成果: ジャーナルへの寄稿編集

Animals
Cytokines
Invertebrates
44 引用 (Scopus)

Functional and structural diversities of C-reactive proteins present in horseshoe crab hemolymph plasma

Iwaki, D., Osaki, T., Mizunoe, Y., Wai, S. N., Iwanaga, S. & Kawabata, S. I., 9 1 1999, : : European Journal of Biochemistry. 264, 2, p. 314-326 13 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemolymph
C-Reactive Protein
Sepharose
Plasmas
149 引用 (Scopus)

Functional Conversion of Hemocyanin to Phenoloxidase by Horseshoe Crab Antimicrobial Peptides

Nagai, T., Osaki, T. & Kawabata, S. I., 7 20 2001, : : Journal of Biological Chemistry. 276, 29, p. 27166-27170 5 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocyanin
Monophenol Monooxygenase
Peptides
Chitin
3 引用 (Scopus)

Genetic engineering approach to develop next-generation reagents for endotoxin quantification

Mizumura, H., Ogura, N., Aketagawa, J., Aizawa, M., Kobayashi, Y., Kawabata, S. I. & Oda, T., 1 1 2017, : : Innate Immunity. 23, 2, p. 136-146 11 p.

研究成果: ジャーナルへの寄稿記事

Genetic Engineering
Endotoxins
Horseshoe Crabs
Insects
Peptide Hydrolases
29 引用 (Scopus)

Head-to-tail polymerization of coagulin, a clottable protein of the horseshoe crab

Kawasaki, H., Nose, T., Muta, T., Iwanaga, S., Shimohigashi, Y. & Kawabata, S. I., 11 10 2000, : : Journal of Biological Chemistry. 275, 45, p. 35297-35301 5 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Thromboplastin
Polymerization
Head
Tail
218 引用 (Scopus)

Highly sensitive peptide‐4‐methylcoumaryl‐7‐amide substrates for blood‐clotting proteases and trypsin

Kawabata, S-I., MIURA, T., MORITA, T., KATO, H., FUJIKAWA, K., IWANAGA, S., TAKADA, K., KIMURA, T. & SAKAKIBARA, S., 1 1 1988, : : European Journal of Biochemistry. 172, 1, p. 17-25 9 p.

研究成果: ジャーナルへの寄稿記事

Trypsin
Peptide Hydrolases
Substrates
Factor XIa
Factor XIIa
155 引用 (Scopus)

Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen

Gokudan, S., Muta, T., Tsuda, R., Koori, K., Kawahara, T., Seki, N., Mizunoe, Y., Wai, S. N., Iwanaga, S. & Kawabata, S. I., 8 31 1999, : : Proceedings of the National Academy of Sciences of the United States of America. 96, 18, p. 10086-10091 6 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lectins
Innate Immunity
Fibrinogen
Hemolymph
78 引用 (Scopus)

Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins

Osaki, T., Omotezako, M., Nagayama, R., Hirata, M., Iwanaga, S., Kasahara, J., Hattori, J., Ito, I., Sugiyama, H. & Kawabata, S. I., 9 10 1999, : : Journal of Biological Chemistry. 274, 37, p. 26172-26178 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocytes
Spiders
Neurotoxins
Chitin
5 引用 (Scopus)

Horseshoe crab hemocyte-derived lectin recognizing specific O-antigens of lipopolysaccharides

Inamori, K., Saito, T., Iwaki, D., Nagira, T., Iwanaga, S., Arisaka, F. & Kawabata, S-I., 1 1 2001, : : Advances in Experimental Medicine and Biology. 484, p. 185-190 6 p.

研究成果: ジャーナルへの寄稿記事

Molecular Sequence Data
Carbohydrate Sequence
Horseshoe Crabs
Hemocytes
O Antigens
124 引用 (Scopus)

Identification of a disaccharide (Xyl-Glc) and a trisaccharide (Xyl2-Glc) O-glycosidically linked to a serine residue in the first epidermal growth factor-like domain of human factors VII and IX and protein Z and bovine protein Z

Nishimura, H., Kawabata, S., Kisiel, W., Hase, S., Ikenaka, T., Takao, T., Shimonishi, Y. & Iwanaga, S., 12 20 1989, : : Journal of Biological Chemistry. 264, 34, p. 20320-20325 6 p.

研究成果: ジャーナルへの寄稿記事

Trisaccharides
Factor VII
Factor IX
Disaccharides
Human engineering
28 引用 (Scopus)

Immunocompetent molecules and their response network in horseshoe crabs

Kawabata, S-I., 12 1 2010, Invertebrate Immunity. Soderhall, K. (版). p. 122-136 15 p. (Advances in Experimental Medicine and Biology; 巻数 708).

研究成果: 著書/レポートタイプへの貢献

Horseshoe Crabs
Lipopolysaccharides
Hemocytes
Molecules
Transglutaminases
70 引用 (Scopus)

Influenza a virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

Yoshizumi, T., Ichinohe, T., Sasaki, O., Otera, H., Kawabata, S-I., Mihara, K. & Koshiba, T., 8 20 2014, : : Nature communications. 5, 4713.

研究成果: ジャーナルへの寄稿記事

influenza
Mitochondria
mitochondria
immunity
viruses
5 引用 (Scopus)

Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity

Lee, S. A., Jang, S. H., Kim, B. H., Shibata, T., Yoo, J., Jung, Y., Kawabata, S-I. & Lee, B. L., 4 1 2018, : : Developmental and Comparative Immunology. 81, p. 116-126 11 p.

研究成果: ジャーナルへの寄稿記事

Metalloproteases
Humoral Immunity
Cellular Immunity
Insects
Innate Immunity
40 引用 (Scopus)

Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide

Kushibiki, T., Kamiya, M., Aizawa, T., Kumaki, Y., Kikukawa, T., Mizuguchi, M., Demura, M., Kawabata, S. I. & Kawano, K., 3 1 2014, : : Biochimica et Biophysica Acta - Proteins and Proteomics. 1844, 3, p. 527-534 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lipopolysaccharides
Peptides
Tryptophan
Fluorescence
2 引用 (Scopus)
Enzyme Precursors
Serine Proteases
Lipopolysaccharides
Chemical activation
Molecules
104 引用 (Scopus)

In vitro activation of pro-phenol-oxidase by two kinds of pro-phenol- oxidase-activating factors isolated from hemolymph of coleopteran, Holotrichia diomphalia larvae

Lee, S. Y., Kwon, T. H., Hyun, J. H., Choi, J. S., Kawabata, S-I., Iwanaga, S. & Lee, B. L., 5 15 1998, : : European Journal of Biochemistry. 254, 1, p. 50-57 8 p.

研究成果: ジャーナルへの寄稿記事

Monophenol Monooxygenase
Hemolymph
Larva
Chemical activation
amidase
28 引用 (Scopus)

Isolation and characterization of Staphylocoagulase chymotryptic fragment. Localization of the procoagulant- and prothrombin-binding domain of this protein

Kawabata, S-I., Morita, T., Miyata, T., Iwanaga, S. & Igarashi, H., 7 9 1986, : : Journal of Biological Chemistry. 261, 3, p. 1427-1433 7 p.

研究成果: ジャーナルへの寄稿記事

Coagulase
Prothrombin
Carrier Proteins
amidase
Proteins

Limulus Clotting Enzyme

Kawabata, S. I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3064-3066 3 p.

研究成果: 著書/レポートタイプへの貢献

clotting enzyme

Limulus Coagulation Factor B

Kawabata, S-I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3063-3064 2 p.

研究成果: 著書/レポートタイプへの貢献

Blood Coagulation Factors

Limulus Coagulation Factor C

Kawabata, S. I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3060-3063 4 p.

研究成果: 著書/レポートタイプへの貢献

Blood Coagulation Factors

Limulus Coagulation Factor G

Kawabata, S-I., Muta, T. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3066-3067 2 p.

研究成果: 著書/レポートタイプへの貢献

Blood Coagulation Factors
59 引用 (Scopus)

Limulus factor D, a 43-kDa protein isolated from horseshoe crab hemocytes, is a serine protease homologue with antimicrobial activity

Kawabata, S-I., Tokunaga, F., Kugi, Y., Motoyama, S., Miura, Y., Hirata, M. & Iwanaga, S., 12 2 1996, : : FEBS Letters. 398, 2-3, p. 146-150 5 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Complement Factor D
Horseshoe Crabs
Hemocytes
Serine Proteases
36 引用 (Scopus)

Limulus intracellular coagulation inhibitor type 3. Purification, characterization, cDNA cloning, and tissue localization

Agarwala, K. L., Kawabata, S. I., Miura, Y., Kuroki, Y. & Iwanaga, S., 10 10 1996, : : Journal of Biological Chemistry. 271, 39, p. 23768-23774 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Cloning
Coagulation
Serpins
Purification
8 引用 (Scopus)

Limulus kexin: A new type of Kex2-like endoprotease specifically expressed in hemocytes of the horseshoe crab

Kawabata, S. I., Saeki, K. & Iwanaga, S., 5 20 1996, : : FEBS Letters. 386, 2-3, p. 201-204 4 p.

研究成果: ジャーナルへの寄稿記事

Furin
Horseshoe Crabs
Hemocytes
Protein Sorting Signals
Gene Library

Limulus Kexin

Kawabata, S. I. & Iwanaga, S., 8 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, 巻 3. p. 3277-3278 2 p.

研究成果: 著書/レポートタイプへの貢献

13 引用 (Scopus)

Microbe-specific C3b deposition in the horseshoe crab complement system in a C2/factor B-dependent or -independent manner

Tagawa, K., Yoshihara, T., Shibata, T., Kitazaki, K., Endo, Y., Fujita, T., Koshiba, T. & Kawabata, S. I., 5 7 2012, : : PloS one. 7, 5, e36783.

研究成果: ジャーナルへの寄稿記事

Merostomata
Horseshoe Crabs
Complement Factor B
Lectins
lectins
18 引用 (Scopus)

Mitochondria and antiviral innate immunity

Koshiba, T., Bashiruddin, N. & Kawabata, S., 12 1 2011, : : International Journal of Biochemistry and Molecular Biology. 2, 3, p. 257-262 6 p.

研究成果: ジャーナルへの寄稿評論記事

Mitochondria
Innate Immunity
Antiviral Agents
Immunity
Signal transduction
116 引用 (Scopus)

Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling

Koshiba, T., Yasukawa, K., Yanagi, Y. & Kawabata, S. I., 2 1 2011, : : Science Signaling. 4, 158, ra7.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Membrane Potential
Antiviral Agents
Membranes
Mitochondria
Innate Immunity
142 引用 (Scopus)

Mitofusin 2 inhibits mitochondrial antiviral signaling

Yasukawa, K., Oshiumi, H., Takeda, M., Ishihara, N., Yanagi, Y., Seya, T., Kawabata, S. I. & Koshiba, T., 8 18 2009, : : Science Signaling. 2, 84, p. ra47

研究成果: ジャーナルへの寄稿記事

Antiviral Agents
Mitochondrial Dynamics
Genes
Chemical activation
Interferon Regulatory Factor-3
7 引用 (Scopus)

Molecular basis of non-self recognition by the horseshoe crab lectins

Kawabata, S. I. & Tsuda, R., 12 1 2002, : : Journal of Endotoxin Research. 8, 6, p. 437-439 3 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Propellers
Lectins
Pathogens
Ligands
62 引用 (Scopus)

Molecular basis of non-self recognition by the horseshoe crab tachylectins

Kawabata, S-I. & Tsuda, R., 9 19 2002, : : Biochimica et Biophysica Acta - General Subjects. 1572, 2-3, p. 414-421 8 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Lectins
Propellers
Pathogens
Ligands

Molecular basis of sugar-pattern recognition in innate immune system

Kawabata, S-I., 1 1 2004, : : Seikagaku. The Journal of Japanese Biochemical Society. 76, 3, p. 201-206 6 p.

研究成果: ジャーナルへの寄稿評論記事

Immune system
Carbohydrate Metabolism
Crystallization
Lectins
Innate Immunity
51 引用 (Scopus)

Molecular cloning and nucleotide sequence of cDNA of microsomal carboxyesterase E1 of rat liver

Takagi, Y., Morohashi, K-I., Kawabata, S-I., Go, M. & Omura, T., 1 1 1988, : : Journal of biochemistry. 104, 5, p. 801-806 6 p.

研究成果: ジャーナルへの寄稿記事

Carboxylesterase
Cloning
Molecular Cloning
Liver
Rats
19 引用 (Scopus)

Molecular cloning and sequence analysis of cDNA coding for rat liver hemoprotein H-450

Ishihara, S., Morohashi, K-I., Sadano, H., Kawabata, S-I., Gotoh, O. & Omura, T., 1 1 1990, : : Journal of biochemistry. 108, 6, p. 899-902 4 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Molecular Cloning
Liver
Sequence Analysis
Rats
103 引用 (Scopus)

Molecular cloning of cDNA for pro-phenol-oxidase-activating factor i, a serine protease is induced by lipopolysaccharide or 1,3-β-glucan in coleopteran insect, Holotrichia diomphalia larvae

Lee, S. Y., Cho, M. Y., Hyun, J. H., Lee, K. M., Homma, K. I., Natori, S., Kawabata, S-I., Iwanaga, S. & Lee, B. L., 11 1 1998, : : European Journal of Biochemistry. 257, 3, p. 615-621 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Glucans
Monophenol Monooxygenase
Cloning
Molecular Cloning
73 引用 (Scopus)

Molecular cloning of Limulus α2-macroglobulin

Iwaki, D., Kawabata, S-I., Miura, Y., Kato, A., Armstrong, P. B., Quigley, J. P., Nielsen, K. L., Dolmer, K., Sottrup-Jensen, L. & Iwanaga, S., 1 1 1996, : : European Journal of Biochemistry. 242, 3, p. 822-831 10 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Macroglobulins
Cloning
Molecular Cloning
Hemocytes