Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2018

2006
81 引用 (Scopus)

Recognition of pathogens and activation of immune responses in Drosophila and horseshoe crab innate immunity

Kurata, S., Ariki, S. & Kawabata, S-I., 6 2 2006, : : Immunobiology. 211, 4, p. 237-249 13 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Hemocytes
Innate Immunity
Drosophila
Lipopolysaccharides
15 引用 (Scopus)

Structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation

Friedrich, R., Panizzi, P., Kawabata, S-I., Bode, W., Bock, P. E. & Fuentes-Prior, P., 1 13 2006, : : Journal of Biological Chemistry. 281, 2, p. 1188-1195 8 p.

研究成果: ジャーナルへの寄稿記事

Coagulase
Prothrombin
Chemical activation
Thrombin
Enzyme Precursors
2005
17 引用 (Scopus)

An antimicrobial peptide tachyplesin acts as a secondary secretagogue and amplifies lipopolysaccharide-induced hemocyte exocytosis

Ozaki, A., Ariki, S. & Kawabata, S. I., 8 1 2005, : : FEBS Journal. 272, 15, p. 3863-3871 9 p.

研究成果: ジャーナルへの寄稿記事

Hemocytes
Exocytosis
Lipopolysaccharides
GTP-Binding Proteins
Peptides
31 引用 (Scopus)

Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking

Iijima, M., Hashimoto, T., Matsuda, Y., Nagai, T., Yamano, Y., Ichi, T., Osaki, T. & Kawabata, S-I., 9 1 2005, : : FEBS Journal. 272, 18, p. 4774-4786 13 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Transglutaminases
Chitin
Sequence Analysis
Molecular mass
2004
59 引用 (Scopus)

A serine protease zymogen functions as a pattern-recognition receptor for lipopolysaccharides

Ariki, S., Koori, K., Osaki, T., Motoyama, K., Inamori, K. I. & Kawabata, S-I., 1 27 2004, : : Proceedings of the National Academy of Sciences of the United States of America. 101, 4, p. 953-958 6 p.

研究成果: ジャーナルへの寄稿記事

Pattern Recognition Receptors
Hemocytes
Enzyme Precursors
Serine Proteases
Lipopolysaccharides
35 引用 (Scopus)

A Toll-like receptor in horseshoe crabs

Inamori, K. I., Ariki, S. & Kawabata, S-I., 4 1 2004, : : Immunological Reviews. 198, p. 106-115 10 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Toll-Like Receptors
Hemocytes
Leucine
Lipopolysaccharides

Molecular basis of sugar-pattern recognition in innate immune system

Kawabata, S-I., 1 1 2004, : : Seikagaku. The Journal of Japanese Biochemical Society. 76, 3, p. 201-206 6 p.

研究成果: ジャーナルへの寄稿評論記事

Immune system
Carbohydrate Metabolism
Crystallization
Lectins
Innate Immunity
77 引用 (Scopus)

Peptidoglycan Recognition Proteins Involved in 1,3-β -D-Glucan-dependent Prophenoloxidase Activation System of Insect

Lee, M. H., Osaki, T., Lee, J. Y., Baek, M. J., Zhang, R., Park, J. W., Kawabata, S. I., Söderhäll, K. & Lee, B. L., 1 30 2004, : : Journal of Biological Chemistry. 279, 5, p. 3218-3227 10 p.

研究成果: ジャーナルへの寄稿記事

Insects
Chemical activation
Peptidoglycan
Monophenol Monooxygenase
Pattern recognition
1 引用 (Scopus)

Russellysin

Kawabata, S-I. & Iwanaga, S., 6 30 2004, Aspartic and Metallo Peptidases. Elsevier Inc., 巻 1. p. 683-684 2 p.

研究成果: 著書/レポートタイプへの貢献

russellysin
43 引用 (Scopus)

Structure and function of coagulogen, a clottable protein in horseshoe crabs

Osaki, T. & Kawabata, S-I., 6 2004, : : Cellular and Molecular Life Sciences. 61, 11, p. 1257-1265 9 p.

研究成果: ジャーナルへの寄稿評論記事

Arthropod Proteins
Thromboplastin
Coagulation
Horseshoe Crabs
Transglutaminases

Trimerelysin I

Kawabata, S-I. & Iwanaga, S., 6 30 2004, Aspartic and Metallo Peptidases. Elsevier Inc., 巻 1. p. 702-703 2 p.

研究成果: 著書/レポートタイプへの貢献

Trimerelysin II

Kawabata, S-I. & Iwanaga, S., 6 30 2004, Aspartic and Metallo Peptidases. Elsevier Inc., 巻 1. p. 704-705 2 p.

研究成果: 著書/レポートタイプへの貢献

2003
68 引用 (Scopus)

Characterization and Properties of a 1,3-β-D-Glucan Pattern Recognition Protein of Tenebrio molitor Larvae That Is Specifically Degraded by Serine Protease during Prophenoloxidase Activation

Zhang, R., Cho, H. Y., Kim, H. S., Ma, Y. G., Osaki, T., Kawabata, S. I., Söderhäll, K. & Lee, B. L., 10 24 2003, : : Journal of Biological Chemistry. 278, 43, p. 42072-42079 8 p.

研究成果: ジャーナルへの寄稿記事

Tenebrio
Serine Proteases
Pattern recognition
Larva
Chemical activation
156 引用 (Scopus)

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Friedrich, R., Panizzi, P., Fuentes-Prior, P., Richter, K., Verhamme, I., Anderson, P. J., Kawabata, S-I., Huber, R., Bode, W. & Bock, P. E., 10 2 2003, : : Nature. 425, 6957, p. 535-539 5 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Coagulase
Blood Coagulation
Trypsinogen
Streptokinase
86 引用 (Scopus)

The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni

Ishikawa, T., Mizunoe, Y., Kawabata, S. I., Takade, A., Harada, M., Wai, S. N. & Yoshida, S. I., 2 1 2003, : : Journal of bacteriology. 185, 3, p. 1010-1017 8 p.

研究成果: ジャーナルへの寄稿記事

Iron-Binding Proteins
Campylobacter jejuni
Hydrogen Peroxide
Iron
Proteins
2002
239 引用 (Scopus)

An immune-responsive Serpin regulates the melanization cascade in Drosophila

De Gregorio, E., Han, S. J., Lee, W. J., Baek, M. J., Osaki, T., Kawabata, S. I., Lee, B. L., Iwanaga, S., Lemaitre, B. & Brey, P. T., 10 1 2002, : : Developmental Cell. 3, 4, p. 581-592 12 p.

研究成果: ジャーナルへの寄稿記事

Serpins
Arthropods
Drosophila
Serine Proteinase Inhibitors
Monophenol Monooxygenase
77 引用 (Scopus)

A zymogen form of masquerade-like serine proteinase homologue is cleaved during pro-phenoloxidase activation by Ca2+ in coleopteran and Tenebrio molitor larvae

Lee, K. Y., Zhang, R., Kim, M. S., Park, J. W., Park, H. Y., Kawabata, S. I. & Lee, B. L., 9 25 2002, : : European Journal of Biochemistry. 269, 17, p. 4375-4383 9 p.

研究成果: ジャーナルへの寄稿記事

Tenebrio
Enzyme Precursors
Serine Proteases
Monophenol Monooxygenase
Larva
43 引用 (Scopus)

Duplicated binding sites for (1→3)-β-D-glucan in the horseshoe crab coagulation factor G. Implications for a molecular basis of the pattern recognition in innate immunity

Takaki, Y., Seki, N., Kawabata, S-I., Iwanaga, S. & Muta, T., 4 19 2002, : : Journal of Biological Chemistry. 277, 16, p. 14281-14287 7 p.

研究成果: ジャーナルへの寄稿記事

Glucans
Innate Immunity
Pattern recognition
Binding Sites
Enzyme Precursors
7 引用 (Scopus)

Molecular basis of non-self recognition by the horseshoe crab lectins

Kawabata, S. I. & Tsuda, R., 12 1 2002, : : Journal of Endotoxin Research. 8, 6, p. 437-439 3 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Propellers
Lectins
Pathogens
Ligands
62 引用 (Scopus)

Molecular basis of non-self recognition by the horseshoe crab tachylectins

Kawabata, S-I. & Tsuda, R., 9 19 2002, : : Biochimica et Biophysica Acta - General Subjects. 1572, 2-3, p. 414-421 8 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Lectins
Propellers
Pathogens
Ligands
9 引用 (Scopus)

Production and characterization of recombinant tachycitin, the Cys-rich chitin-binding protein

Suetake, T., Aizawa, T., Koganesawa, N., Osaki, T., Kobashigawa, Y., Demura, M., Kawabata, S-I., Kawano, K., Tsuda, S. & Nitta, K., 9 1 2002, : : Protein Engineering. 15, 9, p. 763-769 7 p.

研究成果: ジャーナルへの寄稿記事

Chitin
Fungi
Bacteria
Carrier Proteins
Nuclear magnetic resonance
44 引用 (Scopus)

Proline-rich cell surface antigens of horseshoe crab hemocytes are substrates for protein cross-linking with a clotting protein coagulin

Osaki, T., Okino, N., Tokunaga, F., Iwanaga, S. & Kawabata, S-I., 10 18 2002, : : Journal of Biological Chemistry. 277, 42, p. 40084-40090 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocytes
Thromboplastin
Surface Antigens
Proline
23 引用 (Scopus)

Purification, characterization, and cDNA cloning of α-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera

Kakiuchi, M., Okino, N., Sueyoshi, N., Ichinose, S., Omori, A., Kawabata, S-I., Yamaguchi, K. & Ito, M., 1 1 2002, : : Glycobiology. 12, 2, p. 85-94 10 p.

研究成果: ジャーナルへの寄稿記事

Asterina
Starfish
Acetylgalactosamine
Cloning
Lectins
30 引用 (Scopus)

Purification and identification of a tributyltin-binding protein from serum of Japanese flounder, Paralichthys olivaceus

Shimasaki, Y., Oshima, Y., Yokota, Y., Kitano, T., Nakao, M., Kawabata, S-I., Imada, N. & Honjo, T., 1 1 2002, : : Environmental Toxicology and Chemistry. 21, 6, p. 1229-1235 7 p.

研究成果: ジャーナルへの寄稿記事

Flounder
tributyltin
Purification
purification
serum
33 引用 (Scopus)

Structure of the antimicrobial peptide tachystatin A

Fujitani, N., Kawabata, S-I., Osaki, T., Kumaki, Y., Demura, M., Nitta, K. & Kawano, K., 6 28 2002, : : Journal of Biological Chemistry. 277, 26, p. 23651-23657 7 p.

研究成果: ジャーナルへの寄稿記事

Agatoxins
Chitin
Peptides
Defensins
Horseshoe Crabs
2001
149 引用 (Scopus)

Functional Conversion of Hemocyanin to Phenoloxidase by Horseshoe Crab Antimicrobial Peptides

Nagai, T., Osaki, T. & Kawabata, S-I., 7 20 2001, : : Journal of Biological Chemistry. 276, 29, p. 27166-27170 5 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocyanin
Monophenol Monooxygenase
Peptides
Chitin
5 引用 (Scopus)

Horseshoe crab hemocyte-derived lectin recognizing specific O-antigens of lipopolysaccharides

Inamori, K., Saito, T., Iwaki, D., Nagira, T., Iwanaga, S., Arisaka, F. & Kawabata, S-I., 1 1 2001, : : Advances in Experimental Medicine and Biology. 484, p. 185-190 6 p.

研究成果: ジャーナルへの寄稿記事

O Antigens
Lectins
Lipopolysaccharides
Animals
9 引用 (Scopus)

Role of tachylectins in host defense of the Japanese horseshoe crab Tachypleus tridentatus

Kawabata, S-I., Beisel, H. G., Huber, R., Bode, W., Gokudan, S., Muta, T., Tsuda, R., Koori, K., Kawahara, T., Seki, N., Mizunoe, Y., Wai, S. N. & Iwanaga, S., 1 1 2001, : : Advances in experimental medicine and biology. 484, p. 195-202 8 p.

研究成果: ジャーナルへの寄稿記事

Lectins
Blood Proteins
Animals
Binding Sites
108 引用 (Scopus)

The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems

Kairies, N., Beisel, H. G., Fuentes-Prior, P., Tsuda, R., Muta, T., Iwanaga, S., Bode, W., Huber, R. & Kawabata, S-I., 11 20 2001, : : Proceedings of the National Academy of Sciences of the United States of America. 98, 24, p. 13519-13524 6 p.

研究成果: ジャーナルへの寄稿記事

Hemolymph
Blood Coagulation
Innate Immunity
Fibrinogen
Horseshoe Crabs
2000
30 引用 (Scopus)

Activated phenoloxidase from Tenebrio molitor larvae enhances the synthesis of melanin by using a vitellogenin-like protein in the presence of dopamine

Lee, K. M., Lee, K. Y., Choi, H. W., Cho, M. Y., Kwon, T. H., Kawabata, S-I. & Lee, B. L., 7 12 2000, : : European Journal of Biochemistry. 267, 12, p. 3695-3703 9 p.

研究成果: ジャーナルへの寄稿記事

Tenebrio
Vitellogenins
Monophenol Monooxygenase
Melanins
Larva
12 引用 (Scopus)

A horseshoe crab receptor structurally related to Drosophila Toll

Inamori, K. I., Koori, K., Mishima, C., Muta, T. & Kawabata, S-I., 12 1 2000, : : Journal of Endotoxin Research. 6, 5, p. 397-399 3 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Toll-Like Receptors
Drosophila
Lipopolysaccharides
Interleukin-1 Receptors
128 引用 (Scopus)

A link between blood coagulation and prophenol oxidase activation in arthropod host defense

Nagai, T. & Kawabata, S-I., 9 22 2000, : : Journal of Biological Chemistry. 275, 38, p. 29264-29267 4 p.

研究成果: ジャーナルへの寄稿記事

Arthropods
Blood Coagulation
Coagulation
Blood
Horseshoe Crabs
115 引用 (Scopus)

Chitin-binding proteins in invertebrates and plants comprise a common chitin-binding structural motif

Suetake, T., Tsuda, S., Kawabata, S-I., Miura, K., Iwanaga, S., Hikichi, K., Nitta, K. & Kawano, K., 6 16 2000, : : Journal of Biological Chemistry. 275, 24, p. 17929-17932 4 p.

研究成果: ジャーナルへの寄稿記事

Chitin
Invertebrates
Carrier Proteins
Horseshoe Crabs
Hemocytes
29 引用 (Scopus)

Head-to-tail polymerization of coagulin, a clottable protein of the horseshoe crab

Kawasaki, H., Nose, T., Muta, T., Iwanaga, S., Shimohigashi, Y. & Kawabata, S-I., 11 10 2000, : : Journal of Biological Chemistry. 275, 45, p. 35297-35301 5 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Thromboplastin
Polymerization
Head
Tail
4 引用 (Scopus)

Nonself-recognizing lectins in invertebrate innate immunity

Kawabata, S-I., 1 1 2000, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 45, 5, p. 679-689 11 p.

研究成果: ジャーナルへの寄稿評論記事

Protein Conformation
Invertebrates
Lectins
Innate Immunity
C-Reactive Protein
1999
56 引用 (Scopus)

A newly identified horseshoe crab lectin with specificity for blood group A antigen recognizes specific O-antigens of bacterial lipopolysaccharides

Inamori, K. I., Saito, T., Iwaki, D., Nagira, T., Iwanaga, S., Arisaka, F. & Kawabata, S-I., 2 5 1999, : : Journal of Biological Chemistry. 274, 6, p. 3272-3278 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
O Antigens
Blood Group Antigens
Lectins
Lipopolysaccharides
4 引用 (Scopus)

Cloning, sequencing, and functional expression in Escherichia coli of chaperonin (groESL) genes from Vibrio cholerae

Mizunoe, Y., Wai, S. N., Umene, K., Kokubo, T., Kawabata, S-I. & Yoshida, S. I., 1 1 1999, : : Microbiology and Immunology. 43, 6, p. 513-520 8 p.

研究成果: ジャーナルへの寄稿記事

Chaperonins
Vibrio cholerae
Organism Cloning
Chaperonin 10
Escherichia coli
44 引用 (Scopus)

Functional and structural diversities of C-reactive proteins present in horseshoe crab hemolymph plasma

Iwaki, D., Osaki, T., Mizunoe, Y., Wai, S. N., Iwanaga, S. & Kawabata, S. I., 9 1 1999, : : European Journal of Biochemistry. 264, 2, p. 314-326 13 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemolymph
C-Reactive Protein
Sepharose
Plasmas
155 引用 (Scopus)

Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen

Gokudan, S., Muta, T., Tsuda, R., Koori, K., Kawahara, T., Seki, N., Mizunoe, Y., Wai, S. N., Iwanaga, S. & Kawabata, S-I., 8 31 1999, : : Proceedings of the National Academy of Sciences of the United States of America. 96, 18, p. 10086-10091 6 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lectins
Innate Immunity
Fibrinogen
Hemolymph
76 引用 (Scopus)

Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins

Osaki, T., Omotezako, M., Nagayama, R., Hirata, M., Iwanaga, S., Kasahara, J., Hattori, J., Ito, I., Sugiyama, H. & Kawabata, S. I., 9 10 1999, : : Journal of Biological Chemistry. 274, 37, p. 26172-26178 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocytes
Spiders
Neurotoxins
Chitin
17 引用 (Scopus)

Purification, characterization, and amino acid sequence of an embryonic lectin in perivitelline fluid of the horseshoe crab

Nagai, T., Kawabata, S-I., Shishikura, F. & Sugita, H., 12 31 1999, : : Journal of Biological Chemistry. 274, 53, p. 37673-37678 6 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lectins
Purification
Amino Acid Sequence
Amino Acids
78 引用 (Scopus)

Role of lectins in the innate immunity of horseshoe crab

Kawabata, S-I. & Iwanaga, S., 6 1 1999, : : Developmental and Comparative Immunology. 23, 4-5, p. 391-400 10 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lectins
Innate Immunity
Lipopolysaccharides
Hemolymph
133 引用 (Scopus)

Tachylectin-2: Crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus

Beisel, H. G., Kawabata, S-I., Iwanaga, S., Huber, R. & Bode, W., 5 4 1999, : : EMBO Journal. 18, 9, p. 2313-2322 10 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lectins
Innate Immunity
Acetylglucosamine
Crystal structure
1998
79 引用 (Scopus)
Horseshoe Crabs
Hemolymph
Agglutination
Phylogeny
Innate Immunity
104 引用 (Scopus)

In vitro activation of pro-phenol-oxidase by two kinds of pro-phenol- oxidase-activating factors isolated from hemolymph of coleopteran, Holotrichia diomphalia larvae

Lee, S. Y., Kwon, T. H., Hyun, J. H., Choi, J. S., Kawabata, S-I., Iwanaga, S. & Lee, B. L., 5 15 1998, : : European Journal of Biochemistry. 254, 1, p. 50-57 8 p.

研究成果: ジャーナルへの寄稿記事

Monophenol Monooxygenase
Hemolymph
Larva
Chemical activation
amidase
102 引用 (Scopus)

Molecular cloning of cDNA for pro-phenol-oxidase-activating factor i, a serine protease is induced by lipopolysaccharide or 1,3-β-glucan in coleopteran insect, Holotrichia diomphalia larvae

Lee, S. Y., Cho, M. Y., Hyun, J. H., Lee, K. M., Homma, K. I., Natori, S., Kawabata, S-I., Iwanaga, S. & Lee, B. L., 11 1 1998, : : European Journal of Biochemistry. 257, 3, p. 615-621 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Glucans
Monophenol Monooxygenase
Cloning
Molecular Cloning
230 引用 (Scopus)

New types of clotting factors and defense molecules found in horseshoe crab hemolymph: Their structures and functions

Iwanaga, S., Kawabata, S-I. & Muta, T., 1 1998, : : Journal of Biochemistry. 123, 1, p. 1-15 15 p.

研究成果: ジャーナルへの寄稿評論記事

Horseshoe Crabs
Blood Coagulation Factors
Hemolymph
Hemocytes
Molecules
6 引用 (Scopus)

Purification of a novel muscle cell growth factor S-myotrophin from porcine skeletal muscle

Hayashi, T., Takeshita, K., Tsuchida, N., Kitano, K., Kawabata, S-I., Iwanaga, S. & Ito, T., 8 1 1998, : : International Journal of Biochemistry and Cell Biology. 30, 8, p. 897-908 12 p.

研究成果: ジャーナルへの寄稿記事

Cell growth
Muscle Cells
Purification
Muscle
Intercellular Signaling Peptides and Proteins
104 引用 (Scopus)

Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity

Koo, J. C., Lee, S. Y., Chun, H. J., Cheong, Y. H., Choi, J. S., Kawabata, S-I., Miyagi, M., Tsunasawa, S., Ha, K. S., Bae, D. W., Han, C. D., Lee, B. L. & Cho, M. J., 1 15 1998, : : Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. 1382, 1, p. 80-90 11 p.

研究成果: ジャーナルへの寄稿記事

Ipomoea nil
Adenosine Monophosphate
Seed
Seeds
Chitin
185 引用 (Scopus)

Vibrio cholerae O1 strain TSI-4 produces the exopolysaccharide materials that determine colony morphology, stress resistance, and biofilm formation

Wai, S. N., Mizunoe, Y., Takade, A., Kawabata, S-I. & Yoshida, S. I., 10 1 1998, : : Applied and environmental microbiology. 64, 10, p. 3648-3655 8 p.

研究成果: ジャーナルへの寄稿記事

Vibrio cholerae O1
stress resistance
cholera
exopolysaccharides
Biofilms