Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2018

1997
84 引用 (Scopus)

A newly identified horseshoe crab lectin with binding specificity to O- antigen of bacterial lipopolysaccharides

Saito, T., Hatada, M., Iwanaga, S. & Kawabata, S-I., 12 5 1997, : : Journal of Biological Chemistry. 272, 49, p. 30703-30708 6 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
O Antigens
Lectins
Lipopolysaccharides
Hemocytes
4 引用 (Scopus)

Big defensin and tachylectins-1 and -2.

Kawabata, S-I. & Iwanaga, S., 1 1 1997, : : Methods in molecular biology (Clifton, N.J.). 78, p. 51-61 11 p.

研究成果: ジャーナルへの寄稿記事

Cytoplasmic Granules
Defensins
Hemagglutination Tests
Horseshoe Crabs
Hemocytes
43 引用 (Scopus)

Biochemical and physicochemical characterization of normal and variant forms of human MTH1 protein with antimutagenic activity

Yakushiji, H., Maraboeuf, F., Takahashi, M., Deng, Z. S., Kawabata, S-I., Nakabeppu, Y. & Sekiguchi, M., 9 1 1997, : : Mutation Research - DNA Repair. 384, 3, p. 181-194 14 p.

研究成果: ジャーナルへの寄稿記事

Proteins
Substitution reactions
Valine
Circular Dichroism
Methionine
19 引用 (Scopus)

CDNA cloning, tissue distribution, and subcellular localization of horseshoe crab big defensin

Kawabata, S-I., Saito, T., Saeki, K., Okino, N., Mizutani, A., Toh, Y. & Iwanaga, S., 1 1 1997, : : Biological Chemistry. 378, 3-4, p. 289-292 4 p.

研究成果: ジャーナルへの寄稿記事

Defensins
Horseshoe Crabs
Cloning
Tissue Distribution
Organism Cloning
50 引用 (Scopus)

Purification and Characterization of Prophenoloxidase from the Hemolymph of Coleopteran Insect, Holotrichia diomphalia Larvae

Kwon, T. H., Lee, S. Y., Lee, J. H., Choi, J. S., Kawabata, S-I., Iwanaga, S. & Lee, B. L., 2 28 1997, : : Molecules and Cells. 7, 1, p. 90-97 8 p.

研究成果: ジャーナルへの寄稿記事

Monophenol Monooxygenase
Hemolymph
Larva
Insects
Dextran Sulfate
7 引用 (Scopus)

Tissue distribution and subcellular localization of rabbit liver metalloendopeptidase

Nakagawa, K., Kawabata, S-I., Nakashima, Y., Iwanaga, S. & Sueishi, K., 1 1 1997, : : Journal of Histochemistry and Cytochemistry. 45, 1, p. 41-47 7 p.

研究成果: ジャーナルへの寄稿記事

Metalloendopeptidases
Tissue Distribution
Rabbits
Liver
thimet oligopeptidase
1996
35 引用 (Scopus)

A cysteine protease inhibitor stored in the large granules of horseshoe crab hemocytes: Purification, characterization, cDNA cloning and tissue localization

Agarwala, K. L., Kawabata, S-I., Hirata, M., Miyagi, M., Tsunasawa, S. & Iwanaga, S., 1 1996, : : Journal of Biochemistry. 119, 1, p. 85-94 10 p.

研究成果: ジャーナルへの寄稿記事

Cystatins
Cysteine Proteinase Inhibitors
Horseshoe Crabs
Hemocytes
Cloning
59 引用 (Scopus)

Limulus factor D, a 43-kDa protein isolated from horseshoe crab hemocytes, is a serine protease homologue with antimicrobial activity

Kawabata, S-I., Tokunaga, F., Kugi, Y., Motoyama, S., Miura, Y., Hirata, M. & Iwanaga, S., 12 2 1996, : : FEBS Letters. 398, 2-3, p. 146-150 5 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Complement Factor D
Horseshoe Crabs
Hemocytes
Serine Proteases
36 引用 (Scopus)

Limulus intracellular coagulation inhibitor type 3. Purification, characterization, cDNA cloning, and tissue localization

Agarwala, K. L., Kawabata, S-I., Miura, Y., Kuroki, Y. & Iwanaga, S., 10 10 1996, : : Journal of Biological Chemistry. 271, 39, p. 23768-23774 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Cloning
Coagulation
Serpins
Purification
8 引用 (Scopus)

Limulus kexin: A new type of Kex2-like endoprotease specifically expressed in hemocytes of the horseshoe crab

Kawabata, S. I., Saeki, K. & Iwanaga, S., 5 20 1996, : : FEBS Letters. 386, 2-3, p. 201-204 4 p.

研究成果: ジャーナルへの寄稿記事

Furin
Horseshoe Crabs
Hemocytes
Protein Sorting Signals
Gene Library
72 引用 (Scopus)

Molecular cloning of Limulus α2-macroglobulin

Iwaki, D., Kawabata, S-I., Miura, Y., Kato, A., Armstrong, P. B., Quigley, J. P., Nielsen, K. L., Dolmer, K., Sottrup-Jensen, L. & Iwanaga, S., 1 1 1996, : : European Journal of Biochemistry. 242, 3, p. 822-831 10 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Macroglobulins
Cloning
Molecular Cloning
Hemocytes
Molecular Sequence Data
alpha-Macroglobulins
Horseshoe Crabs
Hemocytes
Protease Inhibitors
108 引用 (Scopus)

Tachycitin, a small granular component in horseshoe crab hemocytes, is an antimicrobial protein with chitin-binding activity

Kawabata, S-I., Nagayama, R., Hirata, M., Shigenaga, T., Lal Agarwala, K., Saito, T., Cho, J., Nakajima, H., Takagi, T. & Iwanaga, S., 1 1 1996, : : Journal of biochemistry. 120, 6, p. 1253-1260 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocytes
Chitin
Defensins
Proteins
1995
58 引用 (Scopus)

A limulus intracellular coagulation inhibitor type 2: Purification, characterization, cDNA cloning, and tissue localization

Miura, Y., Kawabata, S-I., Wakamiya, Y., Nakamura, T. & Iwanaga, S., 1 13 1995, : : Journal of Biological Chemistry. 270, 2, p. 558-565 8 p.

研究成果: ジャーナルへの寄稿記事

Serpins
Horseshoe Crabs
Cloning
Coagulation
Purification
17 引用 (Scopus)

An abnormal fibrinogen Fukuoka II (Gly-Bβ15 → Cys) characterized by defective fibrin lateral association and mixed disulfide formation

Kamura, T., Tsuda, H., Yae, Y., Hattori, S., Ohga, S., Shibata, Y., Kawabata, S-I. & Hamasaki, N., 1 1 1995, : : Journal of Biological Chemistry. 270, 49, p. 29392-29399 8 p.

研究成果: ジャーナルへの寄稿記事

Abnormal Fibrinogens
Fibrin
Disulfides
Fibrinogen
Association reactions
12 引用 (Scopus)

Annexin V is localized in association with Z-line of rat cardiac myocytes

Wang, L., Rahman, M. M., Iida, H., Inai, T., Kawabata, S-I., Iwanaga, S. & Shibata, Y., 1 1 1995, : : Cardiovascular research. 30, 3, p. 363-371 9 p.

研究成果: ジャーナルへの寄稿記事

Annexin A5
Cardiac Myocytes
Actins
Annexins
Fluorescence Microscopy
140 引用 (Scopus)

A novel big defensin identified in horseshoe crab hemocytes: Isolation, amino acid sequence, and antibacterial activity

Saito, T., Kawabata, S-I., Shigenaga, T., Takayenoki, Y., Cho, J., Nakajima, H., Hirata, M. & Iwanaga, S., 1 1 1995, : : Journal of Biochemistry. 117, 5, p. 1131-1137 7 p.

研究成果: ジャーナルへの寄稿記事

Defensins
Horseshoe Crabs
Hemocytes
Amino Acid Sequence
Amino Acids
71 引用 (Scopus)

A novel type of limulus lectin-L6: Purification, primary structure, and antibacterial activity

Saito, T., Kawabata, S-I., Hirata, M. & Iwanaga, S., 6 16 1995, : : Journal of Biological Chemistry. 270, 24, p. 14493-14499 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Purification
Lipopolysaccharides
Bacteria
lysyl endopeptidase
20 引用 (Scopus)

A Sapecin Homologue of Holotrichia Diomphalia: Purification, Sequencing and Determination of Disulfide Pairs

Lee, S., Moon, H., Lee, B., Kawabata, S-I., Natori, S. & Kurata, S., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 3, p. 457-459 3 p.

研究成果: ジャーナルへの寄稿記事

Hemolymph
Gram-Positive Bacteria
Gram-Negative Bacteria
Disulfides
Larva
79 引用 (Scopus)

cDNA Cloning and Deduced Amino Acid Sequence of Prothrombin Activator (Ecarin) from Kenyan Echis carinatus Venom

Nishida, S., Fujita, T., Kohno, N., Atoda, H., Morita, T., Takeya, H., Kido, I., Paine, M. J. I., Kawabata, S-I. & Iwanaga, S., 1 1 1995, : : Biochemistry. 34, 5, p. 1771-1778 8 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Venoms
Prothrombin
Organism Cloning
Amino Acid Sequence
128 引用 (Scopus)

Nucleotide sequence of the cDNA encoding the proenzyme of phenol oxidase of A1 Drosophila melanogaster

Fujimoto, K., Okino, N., Kawabata, S. I., Iwanaga, S. & Ohnishi, E., 8 31 1995, : : Proceedings of the National Academy of Sciences of the United States of America. 92, 17, p. 7769-7773 5 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Monophenol Monooxygenase
Drosophila melanogaster
Hemocyanin
Complementary DNA
61 引用 (Scopus)

Purification, characterization, and cDNA cloning of a 27-kDa lectin (L10) from horseshoe crab hemocytes

Okino, N., Kawabata, S. I., Saito, T., Hirata, M., Takagi, T. & Iwanaga, S., 12 29 1995, : : Journal of Biological Chemistry. 270, 52, p. 31008-31015 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocytes
Cloning
Lectins
Purification
3 引用 (Scopus)

Substrate specificity of rabbit liver metalloendopeptidase and its new fluorogenic peptide substrates

Kojima, N., Kawabata, S-I., Makinose, Y., Nishino, N. & Iwanaga, S., 1 1 1995, : : Journal of biochemistry. 118, 4, p. 855-861 7 p.

研究成果: ジャーナルへの寄稿記事

Metalloendopeptidases
Substrate Specificity
Fluorescent Dyes
Liver
thimet oligopeptidase
1994
40 引用 (Scopus)

Activation Peptide of Human Factor IX Has Oligosaccharides O-Glycosidically Linked to Threonine Residues at 159 and 169

Agarwala, K. L., Kawabata, S-I., Nishimura, H., Iwanaga, S., Takao, T., Murata, H. & Shimonishi, Y., 5 1 1994, : : Biochemistry. 33, 17, p. 5167-5171 5 p.

研究成果: ジャーナルへの寄稿記事

Factor IX
Threonine
Human engineering
Oligosaccharides
Chemical activation
67 引用 (Scopus)
Serpins
Horseshoe Crabs
Cloning
Serine Proteases
Coagulation
81 引用 (Scopus)

CDN a cloning and characterization of mitochondrial import stimulation factor (MSF) purified from rat liver cytosol

Alam, R., Hachiya, N., Sakaguchi, M., Kawabata, S-I., Iwanaga, S., Kitajima, M., Mihara, K. & Omura, T., 1 1 1994, : : Journal of biochemistry. 116, 2, p. 416-425 10 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Liver
Cytosol
14-3-3 Proteins
Protein Precursors
7 引用 (Scopus)

Chlorophyll deficiency caused by a specific blockage of the C5-pathway in seedlings of virescent mutant rice

Kusumi, K., Inada, H., Kawabata, S-I., Iba, K. & Nishimura, M., 12 1 1994, : : Plant and Cell Physiology. 35, 3, p. 445-449 5 p.

研究成果: ジャーナルへの寄稿記事

Chlorophyll
Seedlings
chlorophyll
rice
mutants
22 引用 (Scopus)

Cloning and sequencing of the cDNA encoding human glutaredoxin

Fernando, M. R., Sumimoto, H., Nanri, H., Kawabata, S. I., Iwanaga, S., Minakami, S., Fukumaki, Y. & Takeshige, K., 6 21 1994, : : BBA - Gene Structure and Expression. 1218, 2, p. 229-231 3 p.

研究成果: ジャーナルへの寄稿記事

Glutaredoxins
Cloning
Organism Cloning
Complementary DNA
Amino Acids
43 引用 (Scopus)

Role of Hemocyte‐Derived Granular Components in Invertebrate Defense

IWANAGA, SADAAKI., MUTA, TATSUSHI., SHIGENAGA, TAKESHI., MIURA, YOSHIKI., SEKI, NORIAKI., SAITO, TETSU. & Kawabata, S-I., 1 1 1994, : : Annals of the New York Academy of Sciences. 712, 1, p. 102-116 15 p.

研究成果: ジャーナルへの寄稿記事

Invertebrates
10 引用 (Scopus)

Structure and function of staphylothrombin

Kawabata, S-I. & Iwanaga, S., 1994, : : Seminars in Thrombosis and Hemostasis. 20, 4, p. 345-350 6 p.

研究成果: ジャーナルへの寄稿小調査

Molecular Sequence Data
Coagulase
Structure-Activity Relationship
Tertiary Protein Structure
Thrombin
37 引用 (Scopus)

Structure-function relationships of tachyplesins and their analogues.

Iwanaga, S., Muta, T., Shigenaga, T., Seki, N., Kawano, K., Katsu, T. & Kawabata, S-I., 1 1 1994, : : Ciba Foundation symposium. 186

研究成果: ジャーナルへの寄稿評論記事

Hemocytes
Horseshoe Crabs
Gramicidin
Peptides
Amino Acids
1993
354 引用 (Scopus)

Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo- dGTP, a mutagenic substrate for DNA synthesis

Kunihiko, S., Furuichi, M., Tsuzuki, T., Kakuma, T., Kawabata, S-I., Maki, H. & Sekiguchi, M., 1993, : : Journal of Biological Chemistry. 268, 31, p. 23524-23530 7 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Organism Cloning
Complementary DNA
Nucleotides
DNA
32 引用 (Scopus)
thimet oligopeptidase
Endopeptidases
Protein Sequence Analysis
Substrate Specificity
Liver
20 引用 (Scopus)

Secondary structural features of modules M2 and M3 of barnase in solution by NMR experiment and distance geometry calculation

Ikura, T., Gō, N., Kohda, D., Inagaki, F., Yanagawa, H., Kawabata, M., Kawabata, S. ., Iwanaga, S., Noguti, T. & Gō, M., 8 1993, : : Proteins: Structure, Function, and Bioinformatics. 16, 4, p. 341-356 16 p.

研究成果: ジャーナルへの寄稿記事

Conformations
Nuclear magnetic resonance
Geometry
Biological Evolution
Peptides
1992
25 引用 (Scopus)
Endopeptidases
Vitamin K
Substrate Specificity
Liver
Blood Proteins
1991
10 引用 (Scopus)

A new trisaccharide sugar chain linked to a serine residue in the first EGF-like domain of clotting factors VII and IX and protein Z

Iwanaga, S., Nishimura, H., Kawabata, S-I., Kisiel, W., Hase, S. & Ikenaka, T., 1991, : : Advances in Experimental Medicine and Biology. 281, p. 121-131 11 p.

研究成果: ジャーナルへの寄稿記事

1990
19 引用 (Scopus)

Molecular cloning and sequence analysis of cDNA coding for rat liver hemoprotein H-450

Ishihara, S., Morohashi, K-I., Sadano, H., Kawabata, S-I., Gotoh, O. & Omura, T., 1 1 1990, : : Journal of biochemistry. 108, 6, p. 899-902 4 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Molecular Cloning
Liver
Sequence Analysis
Rats
8 引用 (Scopus)

Monoclonal antibody (VII-M31) to bovine factor VII: A specific epitope in the γ-carboxyglutamic acid domain

Higashi, S., Kawabata, S-I., Nishimura, H., Funasaki, H., Ohyama, S., Miyamoto, S., Funatsu, A. & Iwanaga, S., 1 1 1990, : : Journal of Biochemistry. 108, 4, p. 654-662 9 p.

研究成果: ジャーナルへの寄稿記事

Factor VII
Epitopes
Monoclonal Antibodies
Acids
Antibodies
83 引用 (Scopus)

The structure of (xylose)2glucose-O-serine 53 found in the first epidermal growth factor-like domain of bovine blood clotting factor IX

Hase, S., Nishimura, H., Kawabata, S-I., Iwanaga, S. & Ikenaka, T., 8 29 1990, : : Journal of Biological Chemistry. 265, 4, p. 1858-1861 4 p.

研究成果: ジャーナルへの寄稿記事

Trisaccharides
Factor IX
Blood Coagulation Factors
Xylose
Blood Coagulation
1989
1 引用 (Scopus)

A cryptic fimbrial gene in Serratia marcescens

Moriya, T., Kawabata, S-I., Mizunoe, Y. & Amako, K., 1 1 1989, : : Journal of bacteriology. 171, 12, p. 6629-6636 8 p.

研究成果: ジャーナルへの寄稿記事

Serratia marcescens
Mannose
Genes
Escherichia coli
Cosmids
17 引用 (Scopus)

Blood clotting factor IX B(M) Nagoya. Substitution of arginine 180 by tryptophan and its activation by α-chymotrypsin and rat mast cell chymase

Suehiro, K., Kawabata, S-I., Miyata, T., Takeya, H., Takamatsu, J., Ogata, K., Kamiya, T., Saito, H., Niho, Y. & Iwanaga, S., 12 1 1989, : : Journal of Biological Chemistry. 264, 35, p. 21257-21265 9 p.

研究成果: ジャーナルへの寄稿記事

Chymases
Factor IX
Blood Coagulation Factors
Chymotrypsin
Blood Coagulation
35 引用 (Scopus)

Coagulation factor XII (Hageman factor) Washington D.C. Inactive factor XIIa results from Cys-571 → Ser substitution

Miyata, T., Kawabata, S-I., Iwanaga, S., Takahashi, I., Alving, B. & Saito, H., 1 1 1989, : : Proceedings of the National Academy of Sciences of the United States of America. 86, 21, p. 8319-8322 4 p.

研究成果: ジャーナルへの寄稿記事

Factor XIIa
Factor XII
Serine
Catalytic Domain
Protein Sequence Analysis
14 引用 (Scopus)

Factor IX Kawachinagano: impaired function of the Gla‐domain caused by attached propeptide region due to substitution of arginine by glutamine at position −4

Sugimoto, M., Miyata, T., Kawabata, S-I., Yoshioka, A., Fukui, H. & Iwanaga, S., 1 1 1989, : : British Journal of Haematology. 72, 2, p. 216-221 6 p.

研究成果: ジャーナルへの寄稿記事

Glutamine
Arginine
Factor XIa
Factor IX
Hemophilia B
124 引用 (Scopus)

Identification of a disaccharide (Xyl-Glc) and a trisaccharide (Xyl2-Glc) O-glycosidically linked to a serine residue in the first epidermal growth factor-like domain of human factors VII and IX and protein Z and bovine protein Z

Nishimura, H., Kawabata, S-I., Kisiel, W., Hase, S., Ikenaka, T., Takao, T., Shimonishi, Y. & Iwanaga, S., 12 20 1989, : : Journal of Biological Chemistry. 264, 34, p. 20320-20325 6 p.

研究成果: ジャーナルへの寄稿記事

Trisaccharides
Factor VII
Factor IX
Disaccharides
Human engineering
1988
11 引用 (Scopus)

A characteristic property of vitamin K-dependent plasma protein Z

Morita, T., Kaetsu, H., Mizuguchi, J., Kawabata, S-I. & Iwanaga, S., 1 1 1988, : : Journal of biochemistry. 104, 3, p. 368-374 7 p.

研究成果: ジャーナルへの寄稿記事

Vitamin K
Calcium
Binding Sites
Proteolysis
Thrombin
85 引用 (Scopus)

Amino acid sequence of a coagulant enzyme, flavoxobin, from Trimeresurus flavoviridis venom

Shieh, T. C., Kawabata, S-I., Kihara, H., Ohno, M. & Iwanaga, S., 1 1 1988, : : Journal of Biochemistry. 103, 4, p. 596-605 10 p.

研究成果: ジャーナルへの寄稿記事

Coagulants
Venoms
Batroxobin
Amino Acid Sequence
lysyl endopeptidase
18 引用 (Scopus)

A mutant rat strain defficient in induction of a phenobarbital-inducible form of cytochrome P-450 in liver microsomes

Hashimoto, T., Matsumoto, T., Nishizawa, M., Kawabata, S-I., Morohashi, K-I., Handa, S. & Omura, T., 1 1 1988, : : Journal of Biochemistry. 103, 3, p. 487-492 6 p.

研究成果: ジャーナルへの寄稿記事

Mutant Strains Rats
Liver Microsomes
Phenobarbital
Liver
Cytochrome P-450 Enzyme System
82 引用 (Scopus)

A new trisaccharide sugar chain linked to a serine residue in bovine blood coagulation factors VII and IX

Hase, S., Kawabata, S-I., Nishimura, H., Takeya, H., Sueyoshi, T., Miyata, T., Iwanaga, S., Takao, T., Shimonishi, Y. & Ikenaka, T., 1 1 1988, : : Journal of Biochemistry. 104, 6, p. 867-868 2 p.

研究成果: ジャーナルへの寄稿記事

Trisaccharides
Factor VII
Factor IX
Sugars
Serine
13 引用 (Scopus)

Blood clotting factor IX niigata: Substitution of alanine-390 by valine in the catalytic domain

Sugimoto, M., Miyata, T., Kawabata, S-I., Yoshioka, A., Fukui, H., Takahashi, H. & Iwanaga, S., 1 1 1988, : : Journal of biochemistry. 104, 6, p. 878-880 3 p.

研究成果: ジャーナルへの寄稿記事

Factor IX
Blood Coagulation Factors
Valine
Blood Coagulation
Factor IXa
37 引用 (Scopus)

Bovine factor VII. Its purification and complete amino acid sequence

Takeya, H., Kawabata, S-I., Nakagawa, K., Yamamichi, Y., Miyata, T., Iwanaga, S., Takao, T. & Shimonishi, Y., 1 1 1988, : : Journal of Biological Chemistry. 263, 29, p. 14868-14877 10 p.

研究成果: ジャーナルへの寄稿記事

Factor VII
Purification
Amino Acid Sequence
Light
Amino Acids