Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2018

フィルター
記事
2018
5 引用 (Scopus)

Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity

Lee, S. A., Jang, S. H., Kim, B. H., Shibata, T., Yoo, J., Jung, Y., Kawabata, S-I. & Lee, B. L., 4 1 2018, : : Developmental and Comparative Immunology. 81, p. 116-126 11 p.

研究成果: ジャーナルへの寄稿記事

Metalloproteases
Humoral Immunity
Cellular Immunity
Insects
Innate Immunity
1 引用 (Scopus)
Enzyme Precursors
Serine Proteases
Lipopolysaccharides
Chemical activation
Molecules
2017
7 引用 (Scopus)

Drosophila TG-A transglutaminase is secreted via an unconventional Golgi-independent mechanism involving exosomes and two types of fatty acylations

Shibata, T., Hadano, J., Kawasaki, D., Dong, X., Kawabata, S-I. & Sllner, T., 1 1 2017, : : Journal of Biological Chemistry. 292, 25, p. 10723-10734 12 p.

研究成果: ジャーナルへの寄稿記事

Exosomes
Acylation
Transglutaminases
Drosophila
Lipoylation
2 引用 (Scopus)

Genetic engineering approach to develop next-generation reagents for endotoxin quantification

Mizumura, H., Ogura, N., Aketagawa, J., Aizawa, M., Kobayashi, Y., Kawabata, S-I. & Oda, T., 1 1 2017, : : Innate Immunity. 23, 2, p. 136-146 11 p.

研究成果: ジャーナルへの寄稿記事

Genetic Engineering
Endotoxins
Horseshoe Crabs
Insects
Peptide Hydrolases
2 引用 (Scopus)
Takifugu
Saxitoxin
Tetraodontiformes
Tetrodotoxin
Denaturation
3 引用 (Scopus)
Transglutaminases
Polyamines
Masks
Transcription Factors
DNA
2016
4 引用 (Scopus)

RNA interference directed against the Transglutaminase gene triggers dysbiosis of gut microbiota in Drosophila

Sekihara, S., Shibata, T., Hyakkendani, M. & Kawabata, S-I., 11 25 2016, : : Journal of Biological Chemistry. 291, 48, p. 25077-25087 11 p.

研究成果: ジャーナルへの寄稿記事

Dysbiosis
Transglutaminases
Acetobacter
RNA Interference
Diptera
2015
14 引用 (Scopus)

Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins

Shibata, T., Maki, K., Hadano, J., Fujikawa, T., Kitazaki, K., Koshiba, T. & Kawabata, S-I., 1 1 2015, : : PLoS Pathogens. 11, 10, e1005244.

研究成果: ジャーナルへの寄稿記事

Exotoxins
Transglutaminases
Epithelium
Diptera
Proteins
3 引用 (Scopus)

Factor B is the second lipopolysaccharide-binding protease zymogen in the horseshoe crab coagulation cascade

Kobayashi, Y., Takahashi, T., Shibata, T., Ikeda, S., Koshiba, T., Mizumura, H., Oda, T. & Kawabata, S-I., 7 31 2015, : : Journal of Biological Chemistry. 290, 31, p. 19379-19386 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Enzyme Precursors
Complement Factor B
Coagulation
Lipopolysaccharides
2014
65 引用 (Scopus)

Influenza a virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

Yoshizumi, T., Ichinohe, T., Sasaki, O., Otera, H., Kawabata, S-I., Mihara, K. & Koshiba, T., 8 20 2014, : : Nature communications. 5, 4713.

研究成果: ジャーナルへの寄稿記事

influenza
Mitochondria
mitochondria
immunity
viruses
37 引用 (Scopus)

Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide

Kushibiki, T., Kamiya, M., Aizawa, T., Kumaki, Y., Kikukawa, T., Mizuguchi, M., Demura, M., Kawabata, S-I. & Kawano, K., 3 1 2014, : : Biochimica et Biophysica Acta - Proteins and Proteomics. 1844, 3, p. 527-534 8 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Lipopolysaccharides
Peptides
Tryptophan
Fluorescence
8 引用 (Scopus)

The N-terminal Arg residue is essential for autocatalytic activation of a lipopolysaccharide-responsive protease zymogen

Kobayashi, Y., Shiga, T., Shibata, T., Sako, M., Maenaka, K., Koshiba, T., Mizumura, H., Oda, T. & Kawabata, S-I., 9 12 2014, : : Journal of Biological Chemistry. 289, 37, p. 25987-25995 9 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Lipopolysaccharides
Peptide Hydrolases
Chemical activation
Molecules
2013
12 引用 (Scopus)

A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer

Sasaki, O., Yoshizumi, T., Kuboyama, M., Ishihara, T., Suzuki, E., Kawabata, S-I. & Koshiba, T., 5 1 2013, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 5, p. 1017-1027 11 p.

研究成果: ジャーナルへの寄稿記事

Energy Transfer
Mitochondrial Membranes
Antiviral Agents
RNA Virus Infections
Mitochondria
25 引用 (Scopus)

Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish

Shibata, T., Sekihara, S., Fujikawa, T., Miyaji, R., Maki, K., Ishihara, T., Koshiba, T. & Kawabata, S-I., 7 23 2013, : : Science Signaling. 6, 285, ra61.

研究成果: ジャーナルへの寄稿記事

Transglutaminases
Transcription Factors
Diptera
RNA Interference
Proteins
2012
13 引用 (Scopus)

Microbe-specific C3b deposition in the horseshoe crab complement system in a C2/factor B-dependent or -independent manner

Tagawa, K., Yoshihara, T., Shibata, T., Kitazaki, K., Endo, Y., Fujita, T., Koshiba, T. & Kawabata, S-I., 5 7 2012, : : PloS one. 7, 5, e36783.

研究成果: ジャーナルへの寄稿記事

Merostomata
Horseshoe Crabs
Complement Factor B
Lectins
lectins
2011
107 引用 (Scopus)

Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling

Koshiba, T., Yasukawa, K., Yanagi, Y. & Kawabata, S-I., 2 1 2011, : : Science Signaling. 4, 158, ra7.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Membrane Potential
Antiviral Agents
Membranes
Mitochondria
Innate Immunity
30 引用 (Scopus)

Peptidoglycan activation of the proPO-system without a peptidoglycan receptor protein (PGRP)?

Liu, H., Wu, C., Matsuda, Y., Kawabata, S-I., Lee, B. L., Söderhäll, K. & Söderhäll, I., 1 1 2011, : : Developmental and Comparative Immunology. 35, 1, p. 51-61 11 p.

研究成果: ジャーナルへの寄稿記事

Peptidoglycan
Lysine
Lipopolysaccharides
Astacoidea
Proteins
8 引用 (Scopus)

Purification and characterization of tributyltin-binding protein of tiger puffer, Takifugu rubripes

Oba, Y., Yamauchi, A., Hashiguchi, Y., Satone, H., Miki, S., Nassef, M., Shimasaki, Y., Kitano, T., Nakao, M., Kawabata, S-I., Honjo, T. & Oshima, Y., 1 1 2011, : : Comparative Biochemistry and Physiology - C Toxicology and Pharmacology. 153, 1, p. 17-23 7 p.

研究成果: ジャーナルへの寄稿記事

Takifugu
Tetraodontiformes
Purification
Carrier Proteins
Electrophoresis
22 引用 (Scopus)

Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: Implications for mitochondrial inheritance

Koshiba, T., Holman, H. A., Kubara, K., Yasukawa, K., Kawabata, S-I., Okamoto, K., Macfarlane, J. & Shaw, J. M., 1 7 2011, : : Journal of Biological Chemistry. 286, 1, p. 354-362 9 p.

研究成果: ジャーナルへの寄稿記事

rho GTP-Binding Proteins
Mitochondrial Genes
GTP Phosphohydrolases
EF Hand Motifs
Yeast
8 引用 (Scopus)

Tributyltin-binding protein type 1, a lipocalin, prevents inhibition of osteoblastic activity by tributyltin in fish scales

Satone, H., Lee, M., Oba, Y., Kusakabe, T., Akahoshi, E., Miki, S., Suzuki, N., Sasayama, Y., Nassef, M., Shimasaki, Y., Kawabata, S-I., Honjo, T. & Oshima, Y., 5 1 2011, : : Aquatic Toxicology. 103, 1-2, p. 79-84 6 p.

研究成果: ジャーナルへの寄稿記事

Lipocalin 1
tributyltin
binding proteins
Carrier Proteins
Fishes
2010
30 引用 (Scopus)

Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila

Shibata, T., Ariki, S., Shinzawa, N., Miyaji, R., Suyama, H., Sako, M., Inomata, N., Koshiba, T., Kanuka, H. & Kawabata, S-I., 11 17 2010, : : PloS one. 5, 10, e13477.

研究成果: ジャーナルへの寄稿記事

Transglutaminases
protein-glutamine gamma-glutamyltransferase
crosslinking
Morphogenesis
Crosslinking
2009
10 引用 (Scopus)

A novel β-defensin structure: Big defensin changes its N-terminal structure to associate with the target membrane

Kouno, T., Mizuguchi, M., Aizawa, T., Shinoda, H., Demura, M., Kawabata, S-I. & Kawano, K., 8 18 2009, : : Biochemistry. 48, 32, p. 7629-7635 7 p.

研究成果: ジャーナルへの寄稿記事

Defensins
Membranes
Micelles
Nuclear magnetic resonance
Horseshoe Crabs
45 引用 (Scopus)

Factor C acts as a lipopolysaccharide-responsive C3 convertase in horseshoe crab complement activation

Ariki, S., Takahara, S., Shibata, T., Fukuoka, T., Ozaki, A., Endo, Y., Fujita, T., Koshiba, T. & Kawabata, S-I., 12 1 2009, : : Journal of Immunology. 181, 11, p. 7994-8001 8 p.

研究成果: ジャーナルへの寄稿記事

Complement C3-C5 Convertases
Horseshoe Crabs
Complement Activation
Lipopolysaccharides
Gram-Negative Bacteria
6 引用 (Scopus)

Factor G utilizes a carbohydrate-binding cleft that is conserved between horseshoe crab and bacteria for the recognition of β-1,3-D-glucans

Ueda, Y., Ohwada, S., Abe, Y., Shibata, T., Iijima, M., Yoshimitsu, Y., Koshiba, T., Nakata, M., Ueda, T. & Kawabata, S-I., 9 15 2009, : : Journal of Immunology. 183, 6, p. 3810-3818 9 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Carbohydrates
Bacteria
Endo-1,4-beta Xylanases
Cellvibrio
139 引用 (Scopus)

Mitofusin 2 inhibits mitochondrial antiviral signaling

Yasukawa, K., Oshiumi, H., Takeda, M., Ishihara, N., Yanagi, Y., Seya, T., Kawabata, S-I. & Koshiba, T., 8 18 2009, : : Science Signaling. 2, 84

研究成果: ジャーナルへの寄稿記事

Antiviral Agents
Mitochondrial Dynamics
Genes
Chemical activation
Interferon Regulatory Factor-3
2008
24 引用 (Scopus)

A novel β-defensin structure: A potential strategy of big defensin for overcoming resistance by gram-positive bacteria

Kouno, T., Fujitani, N., Mizuguchi, M., Osaki, T., Nishimura, S. I., Kawabata, S-I., Aizawa, T., Demura, M., Nitta, K. & Kawano, K., 10 7 2008, : : Biochemistry. 47, 40, p. 10611-10619 9 p.

研究成果: ジャーナルへの寄稿記事

Defensins
Gram-Positive Bacteria
Bacteria
Micelles
Gram-Negative Bacteria
17 引用 (Scopus)

Tributyltin-binding protein type 1 has a distinctive lipocalin-like structure and is involved in the excretion of tributyltin in Japanese flounder, Paralichthys olivaceus

Satone, H., Oshima, Y., Shimasaki, Y., Tawaratsumida, T., Oba, Y., Takahashi, E., Kitano, T., Kawabata, S-I., Kakuta, Y. & Honjo, T., 12 11 2008, : : Aquatic Toxicology. 90, 4, p. 292-299 8 p.

研究成果: ジャーナルへの寄稿記事

Lipocalins
Flounder
Paralichthys olivaceus
tributyltin
excretion
2007
20 引用 (Scopus)

A cysteine-rich protein from an arthropod stabilizes clotting mesh and immobilizes bacteria at injury sites

Matsuda, Y., Osaki, T., Hashii, T., Koshiba, T. & Kawabata, S-I., 11 16 2007, : : Journal of Biological Chemistry. 282, 46, p. 33545-33552 8 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Hemocytes
Transglutaminases
Cysteine
Bacteria
17 引用 (Scopus)

An arthropod cuticular chitin-binding protein endows injured sites with transglutaminase-dependent mesh

Matsuda, Y., Koshiba, T., Osaki, T., Suyama, H., Arisaka, F., Toh, Y. & Kawabata, S-I., 12 28 2007, : : Journal of Biological Chemistry. 282, 52, p. 37316-37324 9 p.

研究成果: ジャーナルへの寄稿記事

Transglutaminases
Chitin
Arthropods
Carrier Proteins
Horseshoe Crabs
38 引用 (Scopus)
Gram-Negative Bacteria
Lipopolysaccharides
Bacteria
Innate Immunity
Horseshoe Crabs
30 引用 (Scopus)

Purification and characterization of tributyltin-binding protein type 2 from plasma of Japanese flounder, Paralichthys olivaceus

Oba, Y., Shimasaki, Y., Oshima, Y., Satone, H., Kitano, T., Nakao, M., Kawabata, S-I. & Honjo, T., 8 1 2007, : : Journal of biochemistry. 142, 2, p. 229-238 10 p.

研究成果: ジャーナルへの寄稿記事

Flounder
Purification
Carrier Proteins
Plasmas
Electrophoresis
140 引用 (Scopus)

Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERRγ

Matsushima, A., Kakuta, Y., Teramoto, T., Koshiba, T., Liu, X., Okada, H., Tokunaga, T., Kawabata, S-I., Kimura, M. & Shimohigashi, Y., 10 1 2007, : : Journal of biochemistry. 142, 4, p. 517-524 8 p.

研究成果: ジャーナルへの寄稿記事

Endocrine Disruptors
Cytoplasmic and Nuclear Receptors
Estrogen Receptors
Estrogens
Ligands
13 引用 (Scopus)

The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif

Fujitani, N., Kouno, T., Nakahara, T., Takaya, K., Osaki, T., Kawabata, S-I., Mizuguchi, M., Aizawa, T., Demura, M., Nishimura, S. I. & Kawano, K., 4 1 2007, : : Journal of Peptide Science. 13, 4, p. 269-279 11 p.

研究成果: ジャーナルへの寄稿記事

Cystine Knot Motifs
Horseshoe Crabs
Cystine
Chitin
Peptides
2006
15 引用 (Scopus)

Structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation

Friedrich, R., Panizzi, P., Kawabata, S-I., Bode, W., Bock, P. E. & Fuentes-Prior, P., 1 13 2006, : : Journal of Biological Chemistry. 281, 2, p. 1188-1195 8 p.

研究成果: ジャーナルへの寄稿記事

Coagulase
Prothrombin
Chemical activation
Thrombin
Enzyme Precursors
2005
17 引用 (Scopus)

An antimicrobial peptide tachyplesin acts as a secondary secretagogue and amplifies lipopolysaccharide-induced hemocyte exocytosis

Ozaki, A., Ariki, S. & Kawabata, S-I., 8 1 2005, : : FEBS Journal. 272, 15, p. 3863-3871 9 p.

研究成果: ジャーナルへの寄稿記事

Hemocytes
Exocytosis
Lipopolysaccharides
GTP-Binding Proteins
Peptides
31 引用 (Scopus)

Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking

Iijima, M., Hashimoto, T., Matsuda, Y., Nagai, T., Yamano, Y., Ichi, T., Osaki, T. & Kawabata, S-I., 9 1 2005, : : FEBS Journal. 272, 18, p. 4774-4786 13 p.

研究成果: ジャーナルへの寄稿記事

Arthropod Proteins
Transglutaminases
Chitin
Sequence Analysis
Molecular mass
2004
59 引用 (Scopus)

A serine protease zymogen functions as a pattern-recognition receptor for lipopolysaccharides

Ariki, S., Koori, K., Osaki, T., Motoyama, K., Inamori, K. I. & Kawabata, S-I., 1 27 2004, : : Proceedings of the National Academy of Sciences of the United States of America. 101, 4, p. 953-958 6 p.

研究成果: ジャーナルへの寄稿記事

Pattern Recognition Receptors
Hemocytes
Enzyme Precursors
Serine Proteases
Lipopolysaccharides
77 引用 (Scopus)

Peptidoglycan Recognition Proteins Involved in 1,3-β -D-Glucan-dependent Prophenoloxidase Activation System of Insect

Lee, M. H., Osaki, T., Lee, J. Y., Baek, M. J., Zhang, R., Park, J. W., Kawabata, S-I., Söderhäll, K. & Lee, B. L., 1 30 2004, : : Journal of Biological Chemistry. 279, 5, p. 3218-3227 10 p.

研究成果: ジャーナルへの寄稿記事

Insects
Chemical activation
Peptidoglycan
Monophenol Monooxygenase
Pattern recognition
2003
66 引用 (Scopus)

Characterization and Properties of a 1,3-β-D-Glucan Pattern Recognition Protein of Tenebrio molitor Larvae That Is Specifically Degraded by Serine Protease during Prophenoloxidase Activation

Zhang, R., Cho, H. Y., Kim, H. S., Ma, Y. G., Osaki, T., Kawabata, S-I., Söderhäll, K. & Lee, B. L., 10 24 2003, : : Journal of Biological Chemistry. 278, 43, p. 42072-42079 8 p.

研究成果: ジャーナルへの寄稿記事

Tenebrio
Serine Proteases
Pattern recognition
Larva
Chemical activation
153 引用 (Scopus)

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Friedrich, R., Panizzi, P., Fuentes-Prior, P., Richter, K., Verhamme, I., Anderson, P. J., Kawabata, S-I., Huber, R., Bode, W. & Bock, P. E., 10 2 2003, : : Nature. 425, 6957, p. 535-539 5 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Coagulase
Blood Coagulation
Trypsinogen
Streptokinase
86 引用 (Scopus)

The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni

Ishikawa, T., Mizunoe, Y., Kawabata, S-I., Takade, A., Harada, M., Wai, S. N. & Yoshida, S. I., 2 1 2003, : : Journal of bacteriology. 185, 3, p. 1010-1017 8 p.

研究成果: ジャーナルへの寄稿記事

Iron-Binding Proteins
Campylobacter jejuni
Hydrogen Peroxide
Iron
Proteins
2002
237 引用 (Scopus)

An immune-responsive Serpin regulates the melanization cascade in Drosophila

De Gregorio, E., Han, S. J., Lee, W. J., Baek, M. J., Osaki, T., Kawabata, S-I., Lee, B. L., Iwanaga, S., Lemaitre, B. & Brey, P. T., 10 1 2002, : : Developmental Cell. 3, 4, p. 581-592 12 p.

研究成果: ジャーナルへの寄稿記事

Serpins
Arthropods
Drosophila
Serine Proteinase Inhibitors
Monophenol Monooxygenase
75 引用 (Scopus)

A zymogen form of masquerade-like serine proteinase homologue is cleaved during pro-phenoloxidase activation by Ca2+ in coleopteran and Tenebrio molitor larvae

Lee, K. Y., Zhang, R., Kim, M. S., Park, J. W., Park, H. Y., Kawabata, S-I. & Lee, B. L., 9 25 2002, : : European Journal of Biochemistry. 269, 17, p. 4375-4383 9 p.

研究成果: ジャーナルへの寄稿記事

Tenebrio
Enzyme Precursors
Serine Proteases
Monophenol Monooxygenase
Larva
43 引用 (Scopus)

Duplicated binding sites for (1→3)-β-D-glucan in the horseshoe crab coagulation factor G. Implications for a molecular basis of the pattern recognition in innate immunity

Takaki, Y., Seki, N., Kawabata, S-I., Iwanaga, S. & Muta, T., 4 19 2002, : : Journal of Biological Chemistry. 277, 16, p. 14281-14287 7 p.

研究成果: ジャーナルへの寄稿記事

Glucans
Innate Immunity
Pattern recognition
Binding Sites
Enzyme Precursors
15 引用 (Scopus)

Nitric oxide-reductase homologue that contains a copper atom and has cytochrome c-oxidase activity from an aerobic phototrophic bacterium Roseobacter denitrificans

Matsuda, Y., Inamori, K. I., Osaki, T., Eguchi, A., Watanabe, A., Kawabata, S-I., Iba, K. & Arata, H., 2002, : : Journal of Biochemistry. 131, 6, p. 791-800 10 p.

研究成果: ジャーナルへの寄稿記事

Roseobacter
Aerobic bacteria
Aerobic Bacteria
Electron Transport Complex IV
Heme
9 引用 (Scopus)

Production and characterization of recombinant tachycitin, the Cys-rich chitin-binding protein

Suetake, T., Aizawa, T., Koganesawa, N., Osaki, T., Kobashigawa, Y., Demura, M., Kawabata, S-I., Kawano, K., Tsuda, S. & Nitta, K., 9 1 2002, : : Protein Engineering. 15, 9, p. 763-769 7 p.

研究成果: ジャーナルへの寄稿記事

Chitin
Fungi
Bacteria
Carrier Proteins
Nuclear magnetic resonance
44 引用 (Scopus)

Proline-rich cell surface antigens of horseshoe crab hemocytes are substrates for protein cross-linking with a clotting protein coagulin

Osaki, T., Okino, N., Tokunaga, F., Iwanaga, S. & Kawabata, S-I., 10 18 2002, : : Journal of Biological Chemistry. 277, 42, p. 40084-40090 7 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Hemocytes
Thromboplastin
Surface Antigens
Proline
22 引用 (Scopus)

Purification, characterization, and cDNA cloning of α-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera

Kakiuchi, M., Okino, N., Sueyoshi, N., Ichinose, S., Omori, A., Kawabata, S-I., Yamaguchi, K. & Ito, M., 1 1 2002, : : Glycobiology. 12, 2, p. 85-94 10 p.

研究成果: ジャーナルへの寄稿記事

Asterina
Starfish
Acetylgalactosamine
Cloning
Lectins
30 引用 (Scopus)

Purification and identification of a tributyltin-binding protein from serum of Japanese flounder, Paralichthys olivaceus

Shimasaki, Y., Oshima, Y., Yokota, Y., Kitano, T., Nakao, M., Kawabata, S-I., Imada, N. & Honjo, T., 2002, : : Environmental Toxicology and Chemistry. 21, 6, p. 1229-1235 7 p.

研究成果: ジャーナルへの寄稿記事

Flounder
tributyltin
Purification
purification
serum