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研究成果 2001 2019

  • 1005 引用
  • 16 h指数
  • 27 記事
  • 3 評論記事
  • 1
  • 1 コメント/討論
2019

Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones

Katoh-Fukui, Y., Baba, T., Sato, T., Otake, H., Nagakui-Noguchi, Y., Shindo, M., Suyama, M., Ohkawa, Y., Tsumura, H., Morohashi, K. I. & Fukami, M., 3 2019, : : Bone. 120, p. 219-231 13 p.

研究成果: ジャーナルへの寄稿記事

Mesenchymal Stromal Cells
Bone and Bones
Cell Lineage
Genes
Polycomb-Group Proteins
1 引用 (Scopus)

Three populations of adult Leydig cells in mouse testes revealed by a novel mouse HSD3B1-specific rat monoclonal antibody

Yokoyama, C., Chigi, Y., Baba, T., Ohshitanai, A., Harada, Y., Takahashi, F. & Morohashi, K. I., 4 16 2019, : : Biochemical and Biophysical Research Communications. 511, 4, p. 916-920 5 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Testis
Rats
3-Hydroxysteroid Dehydrogenases
Steroids
2018
1 引用 (Scopus)

Ad4BP/SF-1 regulates cholesterol synthesis to boost the production of steroids

Baba, T., Otake, H., Inoue, M., Sato, T., Ishihara, Y., Moon, J. Y., Tsuchiya, M., Miyabayashi, K., Ogawa, H., Shima, Y., Wang, L., Sato, R., Yamazaki, T., Suyama, M., Nomura, M., Choi, M. H., Ohkawa, Y. & Morohashi, K. I., 12 1 2018, : : Communications Biology. 1, 1, 18.

研究成果: ジャーナルへの寄稿記事

公開
steroids
Steroids
Cholesterol
cholesterol
Metabolic Networks and Pathways
3 引用 (Scopus)

Recent progress in understanding the mechanisms of Leydig cell differentiation

Inoue, M., Baba, T. & Morohashi, K. I., 6 15 2018, : : Molecular and Cellular Endocrinology. 468, p. 39-46 8 p.

研究成果: ジャーナルへの寄稿評論記事

Leydig Cells
Androgens
Cell Differentiation
Genes
Testis

Regulation of metabolic pathways in steroidogenic cells by Ad4BP/SF-1

Morohashi, K. I., Inoue, M., Li, B. & Baba, T., 6 12 2018, Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects. Springer Singapore, p. 35-43 9 p.

研究成果: 著書/レポートタイプへの貢献

Metabolic Networks and Pathways
Genes
Gonads
NADP
High-Throughput Nucleotide Sequencing
Adrenal Glands
Steroids
2017
11 引用 (Scopus)

Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development

Miyabayashi, K., Shima, Y., Inoue, M., Sato, T., Baba, T., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 5 1 2017, : : Sexual Development. 11, 2, p. 53-63 11 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Fetal Development
Gene Expression
Testis
Mitochondrial Genes
1 引用 (Scopus)

Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

Shishido, Y., Baba, T., Sato, T., Shima, Y., Miyabayashi, K., Inoue, M., Akiyama, H., Kimura, H., Kanai, Y., Ishihara, Y., Haraguchi, S., Miyazaki, A., Rozman, D., Yamazaki, T., Choi, M. H., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 1 1 2017, : : Scientific reports. 7, 41912.

研究成果: ジャーナルへの寄稿記事

Sertoli Cells
Lactic Acid
Cholesterol
Germ Cells
Nursing
23 引用 (Scopus)

Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues

Igarashi, M., Takasawa, K., Hakoda, A., Kanno, J., Takada, S., Miyado, M., Baba, T., Morohashi, K. I., Tajima, T., Hata, K., Nakabayashi, K., Matsubara, Y., Sekido, R., Ogata, T., Kashimada, K. & Fukami, M., 1 1 2017, : : Human mutation. 38, 1, p. 39-42 4 p.

研究成果: ジャーナルへの寄稿記事

Missense Mutation
Mutation
46, XX Testicular Disorders of Sex Development
46,XY Gonadal Dysgenesis
Ovotesticular Disorders of Sex Development
4 引用 (Scopus)

Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth

Syu, J. S., Baba, T., Huang, J. Y., Ogawa, H., Hsieh, C. H., Hu, J. X., Chen, T. Y., Lin, T. C., Tsuchiya, M., Morohashi, K. I., Huang, B. M., Lu, F. I. & Wang, C. Y., 1 1 2017, : : Scientific reports. 7, 1, 240.

研究成果: ジャーナルへの寄稿記事

Steroidogenic Factor 1
Cyclins
Glycolysis
Growth
Protein Stability
3 引用 (Scopus)

Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells

Li, B., Baba, T., Miyabayashi, K., Sato, T., Shima, Y., Ichinose, T., Miura, D., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 1 1 2017, : : Endocrine Journal. 64, 3, p. 315-324 10 p.

研究成果: ジャーナルへの寄稿記事

Steroidogenic Factor 1
NADP
Genes
Pentose Phosphate Pathway
Chromatin Immunoprecipitation
2016
22 引用 (Scopus)

Isolation and characterization of Fetal Leydig progenitor cells of male mice

Inoue, M., Shima, Y., Miyabayashi, K., Tokunaga, K., Sato, T., Baba, T., Ohkawa, Y., Akiyama, H., Suyama, M. & Morohashi, K. I., 3 2016, : : Endocrinology. 157, 3, p. 1222-1233 12 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Stem Cells
Testis
Growth Factor Receptors
Transcriptome
2015
28 引用 (Scopus)

Fetal leydig cells persist as an androgen-independent subpopulation in the postnatal testis

Shima, Y., Matsuzaki, S., Miyabayashi, K., Otake, H., Baba, T., Kato, S., Huhtaniemi, I. & Morohashi, K. I., 11 2015, : : Molecular Endocrinology. 29, 11, p. 1581-1593 13 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Androgens
Testis
Androgen Receptors
Knockout Mice
5 引用 (Scopus)

Heterogeneity of ovarian theca and interstitial gland cells in Mice

Miyabayashi, K., Tokunaga, K., Otake, H., Baba, T., Shima, Y. & Morohashi, K., 6 3 2015, : : PloS one. 10, 6, e0128352.

研究成果: ジャーナルへの寄稿記事

Genes
Gene expression
Reporter Genes
reporter genes
mice
9 引用 (Scopus)

Testicular dysgenesis/regression without campomelic dysplasia in patients carrying missense mutations and upstream deletion of sox9

Katoh-Fukui, Y., Igarashi, M., Nagasaki, K., Horikawa, R., Nagai, T., Tsuchiya, T., Suzuki, E., Miyado, M., Hata, K., Nakabayashi, K., Hayashi, K., Matsubara, Y., Baba, T., Morohashi, K. I., Igarashi, A., Ogata, T., Takada, S. & Fukami, M., 1 1 2015, : : Molecular Genetics and Genomic Medicine. 3, 6, p. 550-557 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Campomelic Dysplasia
Missense Mutation
XY Disorders of Sex Development 46
Mutation
Exome
2014
35 引用 (Scopus)

Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1

Baba, T., Otake, H., Sato, T., Miyabayashi, K., Shishido, Y., Wang, C. Y., Shima, Y., Kimura, H., Yagi, M., Ishihara, Y., Hino, S., Ogawa, H., Nakao, M., Yamazaki, T., Kang, D., Ohkawa, Y., Suyama, M., Chung, B. C. & Morohashi, K. I., 4 14 2014, : : Nature communications. 5, 3634.

研究成果: ジャーナルへの寄稿記事

Cytoplasmic and Nuclear Receptors
genes
Genes
Tissue
adrenal gland
18 引用 (Scopus)

Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex

Yokoyama, A., Igarashi, K., Sato, T., Takagi, K., Otsuka, M. I., Shishido, Y., Baba, T., Ito, R., Kanno, J., Ohkawa, Y., Morohashi, K. I. & Sugawara, A., 6 27 2014, : : Journal of Biological Chemistry. 289, 26, p. 18152-18162 11 p.

研究成果: ジャーナルへの寄稿記事

Myelin Sheath
Lysine
Transcription Factors
Genes
Histone Demethylases

Regulation of metabolism by orphan receptor regulone

Morohashi, K. I. & Baba, T., 1 1 2014, : : Seikagaku. 86, 6, p. 719-725 7 p.

研究成果: ジャーナルへの寄稿評論記事

Regulon
Gene Expression Regulation
Gonadal Steroid Hormones
Cytoplasmic and Nuclear Receptors
Energy Metabolism
2013
35 引用 (Scopus)

Aristaless Related Homeobox Gene, Arx, Is Implicated in Mouse Fetal Leydig Cell Differentiation Possibly through Expressing in the Progenitor Cells

Miyabayashi, K., Katoh-Fukui, Y., Ogawa, H., Baba, T., Shima, Y., Sugiyama, N., Kitamura, K. & Morohashi, K. I., 6 28 2013, : : PloS one. 8, 6, e68050.

研究成果: ジャーナルへの寄稿記事

homeotic genes
Leydig cells
Leydig Cells
Homeobox Genes
cell differentiation
90 引用 (Scopus)

Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes

Shima, Y., Miyabayashi, K., Haraguchi, S., Arakawa, T., Otake, H., Baba, T., Matsuzaki, S., Shishido, Y., Akiyama, H., Tachibana, T., Tsutsui, K. & Morohashi, K. I., 1 7 2013, : : Molecular Endocrinology. 27, 1, p. 63-73 11 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Sertoli Cells
Testosterone
Testis
Androstenedione
2012
84 引用 (Scopus)

Cbx2, a polycomb group gene, is required for Sry gene expression in mice

Katoh-Fukui, Y., Miyabayashi, K., Komatsu, T., Owaki, A., Baba, T., Shima, Y., Kidokoro, T., Kanai, Y., Schedl, A., Wilhelm, D., Koopman, P., Okuno, Y. & Morohashi, K. I., 2 1 2012, : : Endocrinology. 153, 2, p. 913-924 12 p.

研究成果: ジャーナルへの寄稿記事

sry Genes
Gonads
Testis
Gene Expression
Knockout Mice
1 引用 (Scopus)

Erratum: Identification of an enhancer in the Ad4BP/SF-1 gene specific for fetal leydig cells (Endocrinology (2012) 153, (417-425) DOI: 10.1210/en.2011-1407)

Shima, Y., Miyabayashi, K., Baba, T., Otake, H., Katsura, Y., Oka, S., Zubair, M. & Morohashi, K. I., 11 1 2012, : : Endocrinology. 153, 11, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Leydig Cells
Endocrinology
Genes
33 引用 (Scopus)

Identification of an enhancer in the Ad4BP/SF-1 gene specific for fetal leydig cells

Shima, Y., Miyabayashi, K., Baba, T., Otake, H., Oka, S., Zubair, M. & Morohashi, K. I., 1 2012, : : Endocrinology. 153, 1, p. 417-425 9 p.

研究成果: ジャーナルへの寄稿記事

Steroidogenic Factor 1
Leydig Cells
Genes
Gonads
Adrenal Glands
24 引用 (Scopus)

Steroid hormones and the development of reproductive organs

Morohashi, K., Baba, T. & Tanaka, M., 12 2012, : : Sexual Development. 7, 1-3, p. 61-79 19 p.

研究成果: ジャーナルへの寄稿評論記事

Steroids
Hormones
Steroid Receptors
Androgens
Cell Differentiation
2010
38 引用 (Scopus)

Abnormal epithelial cell polarity and ectopic Epidermal Growth Factor Receptor (EGFR) expression induced in Emx2 KO Embryonic Gonads

Kusaka, M., Katoh-Fukui, Y., Ogawa, H., Miyabayashi, K., Baba, T., Shima, Y., Sugiyama, N., Sugimoto, Y., Okuno, Y., Kodama, R., Iizuka-Kogo, A., Senda, T., Sasaoka, T., Kitamura, K., Aizawa, S. & Morohashi, K. I., 12 1 2010, : : Endocrinology. 151, 12, p. 5893-5904 12 p.

研究成果: ジャーナルへの寄稿記事

Cell Polarity
Tight Junctions
Gonads
Epidermal Growth Factor Receptor
Tyrosine
2008
32 引用 (Scopus)

Disruption of aryl hydrocarbon receptor (AhR) induces regression of the seminal vesicle in aged male mice

Baba, T., Shima, Y., Owaki, A., Mimura, J., Oshima, M., Fujii-Kuriyama, Y. & Morohashi, K. I., 4 1 2008, : : Sexual Development. 2, 1, p. 1-11 11 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Receptors
Seminal Vesicles
Reproduction
Fertility
Testosterone
12 引用 (Scopus)

Importance of forkhead transcription factor Fkhl18 for development of testicular vasculature

Sato, Y., Baba, T., Zubair, M., Miyabayashi, K., Toyama, Y., Maekawa, M., Owaki, A., Mizusaki, H., Sawamura, T., Toshimori, K., Morohashi, K. I. & Katoh-Fukui, Y., 9 1 2008, : : Molecular Reproduction and Development. 75, 9, p. 1361-1371 11 p.

研究成果: ジャーナルへの寄稿記事

Forkhead Transcription Factors
Apoptosis
Testis
Endothelial Cells
Fas Ligand Protein
49 引用 (Scopus)

Mastermind-like domain-containing 1 (MAMLD1 or CXorf6) transactivates the Hes3 promoter, augments testosterone production, and contains the SF1 target sequence

Fukami, M., Wada, Y., Okada, M., Kato, F., Katsumata, N., Baba, T., Morohashi, K. I., Laporte, J., Kitagawa, M. & Ogata, T., 2 29 2008, : : Journal of Biological Chemistry. 283, 9, p. 5525-5532 8 p.

研究成果: ジャーナルへの寄稿記事

Steroidogenic Factor 1
Chromosomes, Human, Pair 1
X Chromosome
Chromosomes
Open Reading Frames
2007
149 引用 (Scopus)

Germ cells are essential for sexual dimorphism in the medaka gonad

Kurokawa, H., Saito, D., Nakamura, S., Katoh-Fukui, Y., Ohta, K., Baba, T., Morohashi, K. I. & Tanaka, M., 10 23 2007, : : Proceedings of the National Academy of Sciences of the United States of America. 104, 43, p. 16958-16963 6 p.

研究成果: ジャーナルへの寄稿記事

Oryzias
Gonads
Germ Cells
Sex Characteristics
Sex Differentiation
2005
171 引用 (Scopus)

Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction

Baba, T., Mimura, J., Nakamura, N., Harada, N., Yamamoto, M., Morohashi, K. I. & Fujii-Kuriyama, Y., 11 1 2005, : : Molecular and cellular biology. 25, 22, p. 10040-10051 12 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Receptors
Reproduction
Poisons
Orphan Nuclear Receptors
Teratogenesis
2002

Action mechanism of dioxin receptor

Fujii-Kuriyama, Y., Mimura, J., Baba, T., Numayama-Tsuruta, K. & Sogawa, K., 1 1 2002, : : Nippon Nogeikagaku Kaishi. 76, 11, p. 1073-1075 3 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Receptors
Cytochrome P-450 CYP1A1
Dioxins
dioxins
mechanism of action
2001
123 引用 (Scopus)

Structure and Expression of the Ah Receptor Repressor Gene

Baba, T., Mimura, J., Gradin, K., Kuroiwa, A., Watanabe, T., Matsuda, Y., Inazawa, J., Sogawa, K. & Fujii-Kuriyama, Y., 8 31 2001, : : Journal of Biological Chemistry. 276, 35, p. 33101-33110 10 p.

研究成果: ジャーナルへの寄稿記事

Genes
Chromosomes
Aryl Hydrocarbon Receptors
Methylcholanthrene
Electrophoretic Mobility Shift Assay