Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1987 2019

フィルター
記事
2019

Base-Resolution Methylome of Retinal Pigment Epithelial Cells Used in the First Trial of Human Induced Pluripotent Stem Cell-Based Autologous Transplantation

Araki, H., Miura, F., Watanabe, A., Morinaga, C., Kitaoka, F., Kitano, Y., Sakai, N., Shibata, Y., Terada, M., Goto, S., Yamanaka, S., Takahashi, M. & Ito, T., 10 8 2019, : : Stem Cell Reports. 13, 4, p. 761-774 14 p.

研究成果: ジャーナルへの寄稿記事

公開
Induced Pluripotent Stem Cells
Retinal Pigments
Autologous Transplantation
Macular Degeneration
DNA Methylation
公開
Single-Stranded DNA
Ligation
Genome
Libraries
DNA Nucleotidylexotransferase
8 引用 (Scopus)

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

Matsuda, T., Irie, T., Katsurabayashi, S., Hayashi, Y., Nagai, T., Hamazaki, N., Adefuin, A. M. D., Miura, F., Ito, T., Kimura, H., Shirahige, K., Takeda, T., Iwasaki, K., Imamura, T. & Nakashima, K., 2 6 2019, : : Neuron. 101, 3, p. 472-485.e7

研究成果: ジャーナルへの寄稿記事

Microglia
Epigenomics
Neurons
Transcription Factors
Genes
2018

DMS-seq for In Vivo Genome-Wide Mapping of Protein-DNA Interactions and Nucleosome Centers

Umeyama, T. & Ito, T., 7 1 2018, : : Current Protocols in Molecular Biology. 123, 1, e60.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Chromosome Mapping
DNA
Genome
Proteins
7 引用 (Scopus)

Epigenetic landscape influences the liver cancer genome architecture

Hama, N., Totoki, Y., Miura, F., Tatsuno, K., Saito-Adachi, M., Nakamura, H., Arai, Y., Hosoda, F., Urushidate, T., Ohashi, S., Mukai, W., Hiraoka, N., Aburatani, H., Ito, T. & Shibata, T., 12 1 2018, : : Nature communications. 9, 1, 1643.

研究成果: ジャーナルへの寄稿記事

genome
Liver Neoplasms
liver
Epigenomics
Liver

Epigenome mapping of human normal purified hepatocytes: Personal epigenome variation and genome-epigenome correlation

Arai, E., Miura, F., Totoki, Y., Yamashita, S., Tian, Y., Gotoh, M., Ojima, H., Nakagawa, H., Takahashi, Y., Nakamura, H., Hama, N., Kato, M., Kimura, H., Suzuki, Y., Ito, T., Shibata, T. & Kanai, Y., 7 2018, : : Epigenomics. 10, 7, p. 955-979 25 p.

研究成果: ジャーナルへの寄稿記事

Methylation
Hepatocytes
Histone Code
Genome
RNA Sequence Analysis
8 引用 (Scopus)

Mapping of histone-binding sites in histone replacement-completed spermatozoa

Yoshida, K., Muratani, M., Araki, H., Miura, F., Suzuki, T., Dohmae, N., Katou, Y., Shirahige, K., Ito, T. & Ishii, S., 12 1 2018, : : Nature communications. 9, 1, 3885.

研究成果: ジャーナルへの寄稿記事

spermatozoa
nuclease
genes
Histones
Spermatozoa

Maternal protein restriction alters the renal ptger1 DNA methylation state in SHRSP offspring

Miyoshi, M., Sato, M., Saito, K., Otani, L., Shirahige, K., Miura, F., Ito, T., Jia, H. & Kato, H., 10 5 2018, : : Nutrients. 10, 10, 1436.

研究成果: ジャーナルへの寄稿記事

Receptors, Prostaglandin E, EP1 Subtype
DNA methylation
DNA Methylation
prostaglandins
kidneys
1 引用 (Scopus)

Triazole linking for preparation of a next-generation sequencing library from single-stranded DNA

Miura, F., Fujino, T., Kogashi, K., Shibata, Y., Miura, M., Isobe, H. & Ito, T., 9 19 2018, : : Nucleic acids research. 46, 16, p. e95

研究成果: ジャーナルへの寄稿記事

公開
Triazoles
Azides
Single-Stranded DNA
Ligation
Alkynes
2017
4 引用 (Scopus)

DMS-Seq for In Vivo Genome-wide Mapping of Protein-DNA Interactions and Nucleosome Centers

Umeyama, T. & Ito, T., 10 3 2017, : : Cell Reports. 21, 1, p. 289-300 12 p.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Chromosome Mapping
Genes
DNA
Proteins
10 引用 (Scopus)

DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells

Sanosaka, T., Imamura, T., Hamazaki, N., Chai, M. C., Igarashi, K., Ideta-Otsuka, M., Miura, F., Ito, T., Fujii, N., Ikeo, K. & Nakashima, K., 9 19 2017, : : Cell Reports. 20, 12, p. 2992-3003 12 p.

研究成果: ジャーナルへの寄稿記事

Neural Stem Cells
Stem cells
Epigenomics
Mental Competency
Neurons
6 引用 (Scopus)

Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9

Yamamoto, S., Hagihara, T., Horiuchi, Y., Okui, A., Wani, S., Yoshida, T., Inoue, T., Tanaka, A., Ito, T., Hirose, Y. & Ohkuma, Y., 3 1 2017, : : Genes to Cells. 22, 3, p. 265-276 12 p.

研究成果: ジャーナルへの寄稿記事

Toll-Like Receptor 9
Cyclin-Dependent Kinases
Up-Regulation
Cyclins
Genes
7 引用 (Scopus)

Software updates in the illumina hiseq platform affect whole-genome bisulfite sequencing

Toh, H., Shirane, K., Miura, F., Kubo, N., Ichiyanagi, K., Hayashi, K., Saitou, M., Suyama, M., Ito, T. & Sasaki, H., 1 5 2017, : : BMC Genomics. 18, 1, 31.

研究成果: ジャーナルへの寄稿記事

Software
Genome
Methylation
Libraries
DNA
10 引用 (Scopus)

The AP-1 transcription factor JunB is required for Th17 cell differentiation

Yamazaki, S., Tanaka, Y., Araki, H., Kohda, A., Sanematsu, F., Arasaki, T., Duan, X., Miura, F., Katagiri, T., Shindo, R., Nakano, H., Ito, T., Fukui, Y., Endo, S. & Sumimoto, H., 12 1 2017, : : Scientific reports. 7, 1, 17402.

研究成果: ジャーナルへの寄稿記事

Th17 Cells
Transcription Factor AP-1
Cell Differentiation
Helper-Inducer T-Lymphocytes
Autoimmune Experimental Encephalomyelitis
2016
6 引用 (Scopus)

A strategy for absolute proteome quantification with mass spectrometry by hierarchical use of peptide-concatenated standards

Kito, K., Okada, M., Ishibashi, Y., Okada, S. & Ito, T., 5 1 2016, : : Proteomics. 16, 10, p. 1457-1473 17 p.

研究成果: ジャーナルへの寄稿記事

Proteome
Mass spectrometry
Mass Spectrometry
Peptides
Proteins
5 引用 (Scopus)

DNA methylation errors in cloned mouse sperm by germ line barrier evasion

Koike, T., Wakai, T., Jincho, Y., Sakashita, A., Kobayashi, H., Mizutani, E., Wakayama, S., Miura, F., Ito, T. & Kono, T., 6 1 2016, : : Biology of Reproduction. 94, 6, 128.

研究成果: ジャーナルへの寄稿記事

DNA Methylation
Germ Cells
Spermatozoa
Genome
Epigenomics
2015
3 引用 (Scopus)

Changepoint detection in base-resolution methylome data reveals a robust signature of methylated domain landscape

Yokoyama, T., Miura, F., Araki, H., Okamura, K. & Ito, T., 8 12 2015, : : BMC Genomics. 16, 1, 594.

研究成果: ジャーナルへの寄稿記事

Methylation
Genome
Cell Lineage
Neoplasms
hydrogen sulfite
12 引用 (Scopus)

DNA methylation and gene expression in Mimulus guttatus

Colicchio, J. M., Miura, F., Kelly, J. K., Ito, T. & Hileman, L. C., 7 7 2015, : : BMC Genomics. 16, 1, 507.

研究成果: ジャーナルへの寄稿記事

Mimulus
DNA Methylation
Methylation
Gene Expression
Cytosine Nucleotides
22 引用 (Scopus)

Highly sensitive targeted methylome sequencing by post-bisulfite adaptor tagging

Miura, F. & Ito, T., 1 1 2015, : : DNA Research. 22, 1, p. 13-18 6 p.

研究成果: ジャーナルへの寄稿記事

DNA
Genome
Costs and Cost Analysis
Firearms
hydrogen sulfite
2014
3 引用 (Scopus)

Detecting protein – DNA interactions using a modified yeast one-hybrid system

Ota, K., Feng, S. Y. & Ito, T., 1 1 2014, : : Methods in Molecular Biology. 1164, p. 39-50 12 p.

研究成果: ジャーナルへの寄稿記事

Reporter Genes
Yeasts
DNA
DNA-Binding Proteins
DNA Methylation
2013
150 引用 (Scopus)

High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

Kobayashi, H., Sakurai, T., Miura, F., Imai, M., Mochiduki, K., Yanagisawa, E., Sakashita, A., Wakai, T., Suzuki, Y., Ito, T., Matsui, Y. & Kono, T., 4 1 2013, : : Genome Research. 23, 4, p. 616-627 12 p.

研究成果: ジャーナルへの寄稿記事

Germ Cells
Methylation
DNA
Epigenomics
Genome
144 引用 (Scopus)

Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases

Shirane, K., Toh, H., Kobayashi, H., Miura, F., Chiba, H., Ito, T., Kono, T. & Sasaki, H., 4 1 2013, : : PLoS genetics. 9, 4, e1003439.

研究成果: ジャーナルへの寄稿記事

methyltransferases
Methyltransferases
methylation
DNA Methylation
Methylation
14 引用 (Scopus)

Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes

Fukuda, K., Ichiyanagi, K., Yamada, Y., Go, Y., Udono, T., Wada, S., Maeda, T., Soejima, H., Saitou, N., Ito, T. & Sasaki, H., 7 1 2013, : : Journal of Human Genetics. 58, 7, p. 446-454 9 p.

研究成果: ジャーナルへの寄稿記事

Pan troglodytes
Hominidae
DNA Methylation
Methylation
Gene Expression
18 引用 (Scopus)
Synthetic Genes
S-Adenosylmethionine
Gene Regulatory Networks
Metabolites
Yeast
20 引用 (Scopus)

The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells

Hayase, J., Kamakura, S., Iwakiri, Y., Yamaguchi, Y., Izaki, T., Ito, T. & Sumimoto, H., 3 1 2013, : : Journal of Cell Biology. 200, 5, p. 635-650 16 p.

研究成果: ジャーナルへの寄稿記事

Epithelial Cells
Proteins
Tight Junctions
Cysts
Madin Darby Canine Kidney Cells
2012
154 引用 (Scopus)

Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

Miura, F., Enomoto, Y., Dairiki, R. & Ito, T., 9 1 2012, : : Nucleic Acids Research. 40, 17

研究成果: ジャーナルへの寄稿記事

Genome
Epigenomics
DNA
hydrogen sulfite
5-Methylcytosine
2011
2 引用 (Scopus)

Highly efficient PCR assay to discriminate allelic DNA methylation status using whole genome amplification

Yamada, Y. & Ito, T., 6 14 2011, : : BMC Research Notes. 4, 179.

研究成果: ジャーナルへの寄稿記事

DNA Methylation
Amplification
Assays
Genes
Genome
19 引用 (Scopus)

Translation initiation: A regulatory role for poly(A) tracts in front of the AUG codon in saccharomyces cerevisiae

Xia, X., Mackay, V., Yao, X., Wu, J., Miura, F., Ito, T. & Morris, D. R., 10 1 2011, : : Genetics. 189, 2, p. 469-478 10 p.

研究成果: ジャーナルへの寄稿記事

Poly A
Codon
Saccharomyces cerevisiae
Untranslated Regions
Yeasts
2010
8 引用 (Scopus)

A yeast one-hybrid system to screen for methylated DNA-binding proteins

Feng, S. Y., Ota, K. & Ito, T., 11 1 2010, : : Nucleic acids research. 38, 20

研究成果: ジャーナルへの寄稿記事

DNA-Binding Proteins
Clone Cells
Yeasts
DNA Methylation
Gene Library
8 引用 (Scopus)

MafB protein stability is regulated by the JNK and ubiquitin-proteasome pathways

Tanahashi, H., Kito, K., Ito, T. & Yoshioka, K., 2 1 2010, : : Archives of Biochemistry and Biophysics. 494, 1, p. 94-100 7 p.

研究成果: ジャーナルへの寄稿記事

MafB Transcription Factor
Protein Stability
Proteasome Endopeptidase Complex
Ubiquitin
Phosphorylation
6 引用 (Scopus)

Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins

Kato, M., Kito, K., Ota, K. & Ito, T., 1 1 2010, : : Proteomics. 10, 1, p. 115-123 9 p.

研究成果: ジャーナルへの寄稿記事

SKP Cullin F-Box Protein Ligases
F-Box Proteins
Ubiquitination
Substrates
Isotope Labeling
2009
25 引用 (Scopus)

Circular permutation of ligand-binding module improves dynamic range of genetically encoded FRET-based nanosensor

Okada, S., Ota, K. & Ito, T., 12 1 2009, : : Protein Science. 18, 12, p. 2518-2527 10 p.

研究成果: ジャーナルへの寄稿記事

Periplasmic Binding Proteins
Nanosensors
Fluorescence Resonance Energy Transfer
Ligands
Proteins
11 引用 (Scopus)

NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.

Ogura, K., Tandai, T., Yoshinaga, S., Kobashigawa, Y., Kumeta, H., Ito, T., Sumimoto, H. & Inagaki, F., 1 1 2009, : : Journal of biochemistry. 146, 3, p. 317-325 9 p.

研究成果: ジャーナルへの寄稿記事

Cell Polarity
Saccharomycetales
Static Electricity
Hydrophobic and Hydrophilic Interactions
Isotopes
2008
48 引用 (Scopus)

Absolute quantification of the budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs

Miura, F., Kawaguchi, N., Yoshida, M., Uematsu, C., Kito, K., Sakaki, Y. & Ito, T., 11 29 2008, : : BMC Genomics. 9, 574.

研究成果: ジャーナルへの寄稿記事

Saccharomycetales
Transcriptome
Complementary DNA
Polymerase Chain Reaction
Messenger RNA
10 引用 (Scopus)

A parallel affinity purification method for selective isolation of polyubiquitinated proteins

Ota, K., Kito, K., Iemura, S. I., Natsume, T. & Ito, T., 8 1 2008, : : Proteomics. 8, 15, p. 3004-3007 4 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitinated Proteins
Purification
Ubiquitin
Bearings (structural)
Ubiquitins
20 引用 (Scopus)

A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p

Ota, K., Kito, K., Okada, S. & Ito, T., 12 1 2008, : : Genes to Cells. 13, 10, p. 1075-1085 11 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Ubiquitinated Proteins
Proteomics
Membrane Proteins
Ubiquitination
13 引用 (Scopus)

Discrimination between stable and dynamic components of protein complexes by means of quantitative proteomics

Kito, K., Kawaguchi, N., Okada, S. & Ito, T., 6 1 2008, : : Proteomics. 8, 12, p. 2366-2370 5 p.

研究成果: ジャーナルへの寄稿記事

Proteomics
Cyclins
Fungal Proteins
Isotopes
Purification
2007
27 引用 (Scopus)
Pheromones
Proline
Yeast
Substitution reactions
Yeasts
65 引用 (Scopus)

A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes

Kito, K., Ota, K., Fujita, T. & Ito, T., 2 1 2007, : : Journal of Proteome Research. 6, 2, p. 792-800 9 p.

研究成果: ジャーナルへの寄稿記事

Multiprotein Complexes
Stoichiometry
Peptides
Proteins
Eukaryotic Initiation Factor-2B
3 引用 (Scopus)

High-throughput fluorescence labelling of full-length cDNA products based on a reconstituted translation system

Kawahashi, Y., Doi, N., Oishi, Y., Tsuda, C., Takashima, H., Baba, T., Mori, H., Ito, T. & Yanagawa, H., 1 1 2007, : : Journal of biochemistry. 141, 1, p. 19-24 6 p.

研究成果: ジャーナルへの寄稿記事

Labeling
Complementary DNA
Fluorescence
Throughput
Proteins
56 引用 (Scopus)

Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae

Kakiuchi, K., Yamauchi, Y., Taoka, M., Iwago, M., Fujita, T., Ito, T., Song, S. Y., Sakai, A., Isobe, T. & Ichimura, T., 7 3 2007, : : Biochemistry. 46, 26, p. 7781-7792 12 p.

研究成果: ジャーナルへの寄稿記事

Cell signaling
Proteomics
Yeast
Saccharomyces cerevisiae
Chitin
9 引用 (Scopus)

Regulation of N-cadherin-based cell-cell interaction by JSAP1 scaffold in PC12h cells

Bayarsaikhan, M., Takino, T., Gantulga, D., Sato, H., Ito, T. & Yoshioka, K., 2 9 2007, : : Biochemical and Biophysical Research Communications. 353, 2, p. 357-362 6 p.

研究成果: ジャーナルへの寄稿記事

Cadherins
Scaffolds
Cell Communication
Nerve Growth Factor
Cells
2006
9 引用 (Scopus)

A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 11q: Comparison with chromosome 21q

Yamada, Y., Shirakawa, T., Taylor, T. D., Okamura, K., Soejima, H., Uchiyama, M., Iwasaka, T., Mukai, T., Muramoto, K. I., Sakaki, Y. & Ito, T., 8 1 2006, : : DNA Sequence - Journal of DNA Sequencing and Mapping. 17, 4, p. 300-306 7 p.

研究成果: ジャーナルへの寄稿記事

CpG Islands
Methylation
Human Chromosomes
Chromosomes
Tandem Repeat Sequences
169 引用 (Scopus)

A large-scale full-length cDNA analysis to explore the budding yeast transcriptome

Miura, F., Kawaguchi, N., Sese, J., Toyoda, A., Hattori, M., Morishita, S. & Ito, T., 11 21 2006, : : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17846-17851 6 p.

研究成果: ジャーナルへの寄稿記事

Saccharomycetales
Transcription Initiation Site
Transcriptome
Open Reading Frames
Complementary DNA
20 引用 (Scopus)

Diverse DNA methylation statuses at alternative promoters of human genes in various tissues

Cheong, J., Yamada, Y., Yamashita, R., Irie, T., Kanai, A., Wakaguri, H., Nakai, K., Ito, T., Saito, I., Sugano, S. & Suzuki, Y., 11 16 2006, : : DNA Research. 13, 4, p. 155-167 13 p.

研究成果: ジャーナルへの寄稿記事

DNA Methylation
CpG Islands
Genes
Methylation
Alleles
17 引用 (Scopus)

Lessons from comparative analysis of species-specific imprinted genes

Okamura, K. & Ito, T., 3 1 2006, : : Cytogenetic and Genome Research. 113, 1-4, p. 159-164 6 p.

研究成果: ジャーナルへの寄稿記事

Genomic Imprinting
Mammals
Genes
Species Specificity
Marsupialia
69 引用 (Scopus)

Transcriptional activators in yeast

Titz, B., Thomas, S., Rajagopala, S. V., Chiba, T., Ito, T. & Uetz, P., 3 20 2006, : : Nucleic acids research. 34, 3, p. 955-967 13 p.

研究成果: ジャーナルへの寄稿記事

Transcriptional Activation
Helix-Loop-Helix Motifs
Yeasts
Fungal Proteins
Asparagine
2005
19 引用 (Scopus)

A novel strategy to design highly specific PCR primers based on the stability and uniqueness of 3′-end subsequences

Miura, F., Uematsu, C., Sakaki, Y. & Ito, T., 12 1 2005, : : Bioinformatics. 21, 24, p. 4363-4370 8 p.

研究成果: ジャーナルへの寄稿記事

Subsequence
Specificity
Uniqueness
Polymerase Chain Reaction
CDNA
14 引用 (Scopus)

Comparative genomics approach toward critical determinants for the imprinting of an evolutionarily conserved gene Impact

Okamura, K., Sakaki, Y. & Ito, T., 4 15 2005, : : Biochemical and Biophysical Research Communications. 329, 3, p. 824-830 7 p.

研究成果: ジャーナルへの寄稿記事

Tandem Repeat Sequences
Genomics
Mammals
Rodentia
Genes
16 引用 (Scopus)

The yeast eIF4E-associated protein Eap1p attenuates GCN4 translation upon TOR-inactivation

matsuo, R., Kubota, H., Obata, T., Kito, K., Ota, K., Kitazono, T., Ibayashi, S., Sasaki, T., Iida, M. & Ito, T., 4 25 2005, : : FEBS Letters. 579, 11, p. 2433-2438 6 p.

研究成果: ジャーナルへの寄稿記事

Sirolimus
Yeast
Yeasts
Proteins
Amino Acids