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研究成果 1982 2019

  • 1452 引用
  • 20 h指数
  • 49 記事
  • 2 コメント/討論
  • 2 評論記事
フィルター
記事
2019

RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121

Sekiguchi, T., Furuno, N., Ishii, T., Hirose, E., Sekiguchi, F., Wang, Y. & Kobayashi, H., 2 1 2019, : : Genes to Cells. 24, 2, p. 151-161 11 p.

研究成果: ジャーナルへの寄稿記事

Hedgehog Proteins
ras Proteins
Monomeric GTP-Binding Proteins
S 6
Inborn Genetic Diseases
2018
5 引用 (Scopus)

Specific binding of PCBP1 to heavily oxidized RNA to induce cell death

Ishii, T., Hayakawa, H., Igawa, T., Sekiguchi, T. & Sekiguchi, M., 6 26 2018, : : Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. 6715-6720 6 p.

研究成果: ジャーナルへの寄稿記事

Oligoribonucleotides
Cell Death
RNA
Clustered Regularly Interspaced Short Palindromic Repeats
Poly C
2015
1 引用 (Scopus)

Phylogenetic relationships of the malay peninsula otters (Lutra sumatrana, lutrogale perspicillata, and aonyx cinereus) based on dna sequences of mitochondrial d-loop region

Rosli, M. K., Abdul-Patah, P., Syed-Shabthar, S. M. F., Burhanuddin, M. N., Sekiguchi, T., Sasaki, H., Shukor, M. N., Yaakop, S. & Md-Zain, B. M., 6 1 2015, : : Journal of Animal and Plant Sciences. 25, 3, p. 836-843 8 p.

研究成果: ジャーナルへの寄稿記事

Lutra
topology
Malaysia
genetic distance
nucleotide sequences
6 引用 (Scopus)

Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells

Ishii, T., Hayakawa, H., Sekiguchi, T., Adachi, N. & Sekiguchi, M., 1 1 2015, : : Free Radical Biology and Medicine. 79, p. 109-116 8 p.

研究成果: ジャーナルへの寄稿記事

Cells
RNA
Messenger RNA
Gene expression
Oxidative stress
2014
7 引用 (Scopus)

Amino acid residues required for Gtr1p-Gtr2p complex formation and its interactions with the Ego1p-Ego3p complex and TORC1 components in yeast

Sekiguchi, T., Kamada, Y., Furuno, N., Funakoshi, M. & Kobayashi, H., 1 1 2014, : : Genes to Cells. 19, 6, p. 449-463 15 p.

研究成果: ジャーナルへの寄稿記事

Yeasts
Amino Acids
Guanosine Triphosphate
ras Proteins
Two-Hybrid System Techniques
15 引用 (Scopus)

A new subspecies identification and population study of the Asian small-clawed otter (Aonyx cinereus) in Malay Peninsula and southern Thailand based on fecal DNA method

Rosli, M. K. A., Syed-Shabthar, S. M. F., Abdul-Patah, P., Abdul-Samad, Z., Abdul, S. N., Burhanuddin, M. N., Zulkifli, N. A., Shukor, M. N., Budsabong, K., Changtragoon, S., Sekiguchi, T., Sasaki, H. & Md-Zain, B. M., 1 1 2014, : : The Scientific World Journal. 2014, 457350.

研究成果: ジャーナルへの寄稿記事

Otters
Malaysia
Thailand
subspecies
Coastal zones
1 引用 (Scopus)

Food habits of the urban Japanese weasels mustela itatsi revealed by faecal DNA analysis

Okawara, Y., Sekiguchi, T., Ikeda, A., Miura, S., Sasaki, H., Fujii, T. & Kaneko, Y., 9 1 2014, : : Mammal Study. 39, 3, p. 155-161 7 p.

研究成果: ジャーナルへの寄稿記事

2013
10 引用 (Scopus)

Elimination and utilization of oxidized guanine nucleotides in the synthesis of RNA and its precursors

Sekiguchi, T., Ito, R., Hayakawa, H. & Sekiguchi, M., 3 22 2013, : : Journal of Biological Chemistry. 288, 12, p. 8128-8135 8 p.

研究成果: ジャーナルへの寄稿記事

Guanine Nucleotides
RNA Precursors
Guanosine Triphosphate
Nucleoside-Diphosphate Kinase
Oxidation
7 引用 (Scopus)

Search for proteins required for accurate gene expression under oxidative stress: Roles of Guanylate Kinase and RNA Polymerase

Inokuchi, H., Ito, R., Sekiguchi, T. & Sekiguchi, M., 11 15 2013, : : Journal of Biological Chemistry. 288, 46, p. 32952-32962 11 p.

研究成果: ジャーナルへの寄稿記事

Guanylate Kinases
Oxidative stress
DNA-Directed RNA Polymerases
Gene expression
Oxidative Stress
2011
3 引用 (Scopus)

Ubiquitin chains in the Dsk2 UBL domain mediate Dsk2 stability and protein degradation in yeast

Sekiguchi, T., Sasaki, T., Funakoshi, M., Ishii, T., Saitoh, Y. H., Kaneko, S. I. & Kobayashi, H., 8 5 2011, : : Biochemical and Biophysical Research Communications. 411, 3, p. 555-561 7 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin
Yeast
Proteolysis
Yeasts
Degradation
2010
2 引用 (Scopus)

New methods for species and sex determination in three sympatric Mustelids, Mustela itatsi, Mustela sibirica and Martes melampus

Sekiguchi, T., Sasaki, H., Kurihara, Y., Watanabe, S., Moriyama, D., Kurose, N., Matsuki, R., Yamazaki, K. & Saeki, M., 11 1 2010, : : Molecular Ecology Resources. 10, 6, p. 1089-1091 3 p.

研究成果: ジャーナルへの寄稿記事

mustelid
Mustelidae
Mustela
sex determination
Martes
2009
7 引用 (Scopus)

Gtr1p differentially associates with Gtr2p and Ego1p

Wang, Y., Kurihara, Y., Sato, T., Toh, H., Kobayashi, H. & Sekiguchi, T., 5 15 2009, : : Gene. 437, 1-2, p. 32-38 7 p.

研究成果: ジャーナルへの寄稿記事

Caffeine
Guanine Nucleotide Exchange Factors
Monomeric GTP-Binding Proteins
Cell Nucleus Active Transport
GTP Phosphohydrolases
2 引用 (Scopus)

Ran GTPase guanine nucleotide exchange factor RCC1 is phosphorylated on serine 11 by cdc2 kinase in vitro

Horiike, Y., Kobayashi, H. & Sekiguchi, T., 4 1 2009, : : Molecular Biology Reports. 36, 4, p. 717-723 7 p.

研究成果: ジャーナルへの寄稿記事

Guanine Nucleotide Exchange Factors
GTP Phosphohydrolases
Serine
Phosphotransferases
Phosphorylation
2008
10 引用 (Scopus)
ras Proteins
GTP Phosphohydrolases
Epigenomics
Gene expression
Yeast
2007
21 引用 (Scopus)

Phosphorylation of threonine 204 of DEAD-box RNA helicase DDX3 by cyclin B/cdc2 in vitro

Sekiguchi, T., Kurihara, Y. & Fukumura, J., 5 11 2007, : : Biochemical and Biophysical Research Communications. 356, 3, p. 668-673 6 p.

研究成果: ジャーナルへの寄稿記事

DEAD-box RNA Helicases
Cyclin B
Phosphorylation
Threonine
Cyclin A
2006
23 引用 (Scopus)

NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47

Sekiguchi, T., Hayano, T., Yanagida, M., Takahashi, N. & Nishimoto, T., 9 1 2006, : : Nucleic acids research. 34, 16, p. 4593-4608 16 p.

研究成果: ジャーナルへの寄稿記事

DEAD-box RNA Helicases
RNA Precursors
Proteins
Ribosomes
Nuclear Proteins
2005
9 引用 (Scopus)

Association of the GTP-binding protein Gtr1p with Rpc19p, a shared subunit of RNA polymerase I and III in yeast Saccharomyces cerevisiae

Todaka, Y., Wang, Y., Tashiro, K., Nakashima, N., Nishimoto, T. & Sekiguchi, T., 8 1 2005, : : Genetics. 170, 4, p. 1515-1524 10 p.

研究成果: ジャーナルへの寄稿記事

RNA Polymerase I
RNA Polymerase III
Guanosine Triphosphate
GTP-Binding Proteins
Saccharomyces cerevisiae
11 引用 (Scopus)
ran GTP-Binding Protein
Saccharomyces cerevisiae Proteins
GTP Phosphohydrolases
Cell proliferation
Yeast
2004
6 引用 (Scopus)

A Hamster Temperature-Sensitive Alanyl-tRNA Synthetase Mutant Causes Degradation of Cell-Cycle Related Proteins and Apoptosis

Wang, Y., Sekiguchi, T., Noguchi, E. & Nishimoto, T., 1 1 2004, : : Journal of Biochemistry. 135, 1, p. 7-16 10 p.

研究成果: ジャーナルへの寄稿記事

Alanine-tRNA Ligase
Cell Cycle Proteins
Cricetinae
Cells
Apoptosis
23 引用 (Scopus)

A Novel Human Nucleolar Protein, Nop132, Binds to the G Proteins, RRAG A/C/D

Sekiguchi, T., Todaka, Y., Wang, Y., Hirose, E., Nakashima, N. & Nishimoto, T., 2 27 2004, : : Journal of Biological Chemistry. 279, 9, p. 8343-8350 8 p.

研究成果: ジャーナルへの寄稿記事

Nuclear Proteins
GTP-Binding Proteins
Guanine Nucleotide Exchange Factors
Monomeric GTP-Binding Proteins
Cell growth
49 引用 (Scopus)

Human DDX3Y, the Y-encoded isoform of RNA helicase DDX3, rescues a hamster temperature-sensitive ET24 mutant cell line with a DDX3X mutation

Sekiguchi, T., Iida, H., Fukumura, J. & Nishimoto, T., 10 15 2004, : : Experimental Cell Research. 300, 1, p. 213-222 10 p.

研究成果: ジャーナルへの寄稿記事

RNA Helicases
DEAD-box RNA Helicases
Cricetinae
Protein Isoforms
Spermatogenesis
2003
35 引用 (Scopus)

A temperature-sensitive mutant of the mammalian RNA helicase, DEAD-BOX X isoform, DBX, defective in the transition from G1 to S phase

Fukumura, J., Noguchi, E., Sekiguchi, T. & Nishimoto, T., 7 1 2003, : : Journal of Biochemistry. 134, 1, p. 71-82 12 p.

研究成果: ジャーナルへの寄稿記事

RNA Helicases
S Phase
Protein Isoforms
Temperature
Cricetinae
2001
138 引用 (Scopus)

Novel G Proteins, Rag C and Rag D, Interact with GTP-binding Proteins, Rag A and Rag B

Sekiguchi, T., Hirose, E., Nakashima, N., Ii, M. & Nishimoto, T., 3 9 2001, : : Journal of Biological Chemistry. 276, 10, p. 7246-7257 12 p.

研究成果: ジャーナルへの寄稿記事

Guanosine Triphosphate
Protein C
GTP-Binding Proteins
Yeast
Saccharomyces cerevisiae
2000
21 引用 (Scopus)

Inhibition of N-linked glycosylation causes apoptosis in hamster BHK21 cells

Yoshimi, M., Sekiguchi, T., Hara, N. & Nishimoto, T., 10 5 2000, : : Biochemical and Biophysical Research Communications. 276, 3, p. 965-969 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Cricetinae
Tunicamycin
Apoptosis
Cells
1999
19 引用 (Scopus)

Overexpression of D-type cyclins, E2F-1, SV40 large T antigen and HPV16 E7 rescue cell cycle arrest of tsBN462 cells caused by the CCG1/TAF(II)250 mutation

Sekiguchi, T., Nishimoto, T. & Hunter, T., 3 11 1999, : : Oncogene. 18, 10, p. 1797-1806 10 p.

研究成果: ジャーナルへの寄稿記事

Cyclin D
Polyomavirus Transforming Antigens
Viral Tumor Antigens
Cyclin D1
Cell Cycle Checkpoints
1998
48 引用 (Scopus)

Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells

Sekiguchi, T. & Hunter, T., 1 22 1998, : : Oncogene. 16, 3, p. 369-380 12 p.

研究成果: ジャーナルへの寄稿記事

Cyclins
Tetracycline
Cricetinae
Cell Death
Growth
69 引用 (Scopus)

RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway

Hirose, E., Nakashima, N., Sekiguchi, T. & Nishimoto, T., 1998, : : Journal of Cell Science. 111, 1, p. 11-21 11 p.

研究成果: ジャーナルへの寄稿記事

GTP Phosphohydrolases
Saccharomyces cerevisiae
Complementary DNA
Cytoplasm
Mutation
1996
25 引用 (Scopus)

D-type cyclin expression is decreased and p21 and p27 CDK inhibitor expression is increased when tsBN462 CCG1/TAF11250 mutant cells arrest in G1 at the restrictive temperature

Sekiguchi, T., Noguchi, E., Hayashida, T., Nakashima, T., Toyoshima, H., Nishimoto, T. & Hunter, T., 1 1 1996, : : Genes to Cells. 1, 7, p. 687-705 19 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclin D
Temperature
Cyclin A
1995
35 引用 (Scopus)

Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor

Sekiguchi, T., Nakashima, T., Hayashida, T., Kuraoka, A., Hashimoto, S., Tsuchida, N., Shibata, Y., Hunter, T. & Nishimoto, T., 1 1 1995, : : Experimental Cell Research. 218, 2, p. 490-498 9 p.

研究成果: ジャーナルへの寄稿記事

Transcription Factor TFIID
Apoptosis
Mutation
Viral Tumor Antigens
Polyomavirus Transforming Antigens
1994
4 引用 (Scopus)

Mammalian cells have two functional RCC1 proteins produced by alternative splicing

Miyabashira, J., Sekiguchi, T. & Nishimoto, T., 8 1994, : : Journal of Cell Science. 107, 8, p. 2203-2208 6 p.

研究成果: ジャーナルへの寄稿記事

Alternative Splicing
Complementary DNA
Cricetinae
Exons
Proteins
10 引用 (Scopus)

Minimum essential region of CCG1/TAFII250 required for complementing the temperature-sensitive cell cycle mutants, tsBN462 and ts13 cells, of hamster BHK21 cells

Noguchi, E., Sekiguchi, T., Nohiro, Y., Hayashida, T., Hirose, E., Hayashi, N. & Nishimoto, T., 11 1 1994, : : Somatic Cell and Molecular Genetics. 20, 6, p. 505-513 9 p.

研究成果: ジャーナルへの寄稿記事

Cricetinae
Cell Cycle
Yeasts
Transcription Factor TFIID
HMGB1 Protein
1 引用 (Scopus)

Preliminary findings of chromosomal alterations and expression of cell cycle genes in head an neck tumors

Nakashima, T., Masuda, A., Sekiguchi, T., Nishimoto, T. & Uemura, T., 8 1 1994, : : European Archives of Oto-Rhino-Laryngology. 251, 1 Supplement

研究成果: ジャーナルへの寄稿記事

cdc Genes
Thyroid Gland
Neck
Head
CDC2 Protein Kinase
12 引用 (Scopus)

Structure of the human CCG1 gene: relationship between the exons/introns and functional domain/modules of the protein

Nakashima, T., Sekiguchi, T., Hidetoshi, S., Kei, Y., Shirou, T., Mitiko, G., Juha, K., David, S. & Takeharu, N., 4 20 1994, : : Gene. 141, 2, p. 193-200 8 p.

研究成果: ジャーナルへの寄稿記事

Introns
Exons
Genes
Cell Cycle Checkpoints
Proteins
55 引用 (Scopus)

The CCG1/TAFII250 gene is mutated in thermosensitive G1 mutants of the BHK21 cell line derived from golden hamster

Toshiro, H., Sekiguchi, T., Eishi, N., Hidetoshi, S., Tomoyuki, O. & Takeharu, N., 4 20 1994, : : Gene. 141, 2, p. 267-270 4 p.

研究成果: ジャーナルへの寄稿記事

Mesocricetus
Complementary DNA
Cell Line
General Transcription Factors
Genes
1993
17 引用 (Scopus)

Molecular cloning and identification of two types of hamster cyclin-dependent kinases: CDK2 and CDK2L

Noguchi, E., Sekiguchi, T., Yamashita, K. & Nishimoto, T., 12 30 1993, : : Biochemical and Biophysical Research Communications. 197, 3, p. 1524-1529 6 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinases
Cloning
Molecular Cloning
Cricetinae
197 引用 (Scopus)

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells

Nakashima, T., Sekiguchi, T., Kuraoka, A., Fukushima, K., Shibata, Y., Komiyama, S. & Nishimoto, T., 1 1 1993, : : Molecular and Cellular Biology. 13, 10, p. 6367-6374 8 p.

研究成果: ジャーナルへの寄稿記事

Molecular Cloning
Cricetinae
Cell Death
Complementary DNA
Apoptosis
1992
48 引用 (Scopus)

DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication

Seino, H., Hisamoto, N., Uzawa, S., Sekiguchi, T. & Nishimoto, T., 7 1992, : : Journal of Cell Science. 102, 3, p. 393-400 8 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Mitosis
DNA
Proteins
S Phase
1991
18 引用 (Scopus)

Molecular cloning of the human gene, CCG2, that complements the BHK-derived temperature-sensitive cell cycle mutant tsBN63: Identity of CCG2 with the human X chromosomal SCAR/RPS4X gene

Watanabe, M., Furuno, N., Goebl, M., Go, M., Miyauchi, K., Sekiguchi, T. & Basilico Nishimito, C. T., 1991, : : Journal of Cell Science. 100, 1, p. 35-43 9 p.

研究成果: ジャーナルへの寄稿記事

Molecular Cloning
Cell Cycle
Temperature
G1 Phase
Genes
10 引用 (Scopus)

RCC1 is a nuclear protein required for coupling activation of cdc2 kinase with DNA synthesis and for start of the cell cycle

Seino, H., Nishitani, H., Seki, T., Hisamoto, N., Tazunoki, T., Shiraki, N., Ohtsubo, M., Yamashita, K., Sekiguchi, T. & Nishimoto, T., 1 1 1991, : : Cold Spring Harbor Symposia on Quantitative Biology. 56, p. 367-375 9 p.

研究成果: ジャーナルへの寄稿記事

Molecular Sequence Data
Polynucleotide 5'-Hydroxyl-Kinase
CDC2 Protein Kinase
enzyme activation
Enzyme Activation
109 引用 (Scopus)

The Human CCG1 Gene, Essential for Progression of the G1 Phase, Encodes a 210-Kilodalton Nuclear DNA-Binding Protein

Sekiguchi, T., Nohiro, Y., Nakamura, Y., Hisamoto, N. & Nishimoto, T., 1 1 1991, : : Molecular and Cellular Biology. 11, 6, p. 3317-3325 9 p.

研究成果: ジャーナルへの寄稿記事

Essential Genes
DNA-Binding Proteins
G1 Phase
Nuclear Proteins
Complementary DNA
1990

Molecular cloning of the unknown genes from mutant cells

Sekiguchi, T., 1 1 1990, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 35, 14, p. 2423-2431 9 p.

研究成果: ジャーナルへの寄稿記事

Molecular Cloning
Mutation
Temperature
DNA
Genes
68 引用 (Scopus)

Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene

Uchida, S., Sekiguchi, T., Nishitani, H., Miyauchi, K., Ohtsubo, M. & Nishimoto, T., 1 1 1990, : : Molecular and Cellular Biology. 10, 2, p. 577-584 8 p.

研究成果: ジャーナルへの寄稿記事

Point Mutation
Cricetinae
Complementary DNA
Chromosomes
Genes
1989
18 引用 (Scopus)

Regional localization of CCG1 gene which complements hamster cell cycle mutation BN462 to Xq11-Xq13

Brown, C. J., Sekiguchi, T., Nishimoto, T. & Willard, H. F., 1 1 1989, : : Somatic Cell and Molecular Genetics. 15, 1, p. 93-96 4 p.

研究成果: ジャーナルへの寄稿記事

Cricetinae
Cell Cycle
Chromosomes, Human, X
Mutation
Hybrid Cells
1988
66 引用 (Scopus)
Cloning
Molecular Cloning
Tandem Repeat Sequences
Complementary DNA
Genes
1987
146 引用 (Scopus)

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

Ohtsubo, M., Kai, R., Furuno, N., Sekiguchi, T., Sekiguchi, M., Hayashida, H., Kuma, K., Miyata, T., Fukushige, S. & Murotsu, T., 1 1 1987, : : Genes & development. 1, 6, p. 585-593 9 p.

研究成果: ジャーナルへの寄稿記事

cdc Genes
Complementary DNA
Chromosomes
Clone Cells
Genes
26 引用 (Scopus)

Isolation of a human X chromosome-linked gene essential for progression from G1 to S phase of the cell cycle

Sekiguchi, T., Yoshida, M. C., Sekiguchi, M. & Nishimoto, T., 1 1 1987, : : Experimental Cell Research. 169, 2, p. 395-407 13 p.

研究成果: ジャーナルへの寄稿記事

Chromosomes, Human, X
X-Linked Genes
S Phase
Cell Cycle
DNA
1983
2 引用 (Scopus)

Recovery of a hybrid vector derived from bovine papilloma virus DNA pBR322 and the HSV tk gene by bacterial transformation with extrachromosomal DNA from transfected rodent cells

Sekiguchi, T., Takeharu, N., Ryosuke, K. & Mutsuo, S., 1 1 1983, : : Gene. 21, 3, p. 267-272 6 p.

研究成果: ジャーナルへの寄稿記事

Bacterial Transformation
DNA Viruses
Thymidine Kinase
Papilloma
Rodentia
6 引用 (Scopus)

Transformation of temperature-sensitive growth mutant of BHK21 cell line to wild-type phenotype with hamster and mouse DNA

Kai, R., Sekiguchi, T., Yamashita, K., Sekiguchi, M. & Nishimoto, T., 11 1 1983, : : Somatic Cell Genetics. 9, 6, p. 673-680 8 p.

研究成果: ジャーナルへの寄稿記事

Cricetinae
Phenotype
Cell Line
Temperature
DNA
1982
31 引用 (Scopus)

Large-scale selection and analysis of temperature-sensitive mutants for cell reproduction from BHK cells

Nishimoto, T., Sekiguchi, T., Kai, R., Yamashita, K., Takahashi, T. & Sekiguchi, M., 11 1 1982, : : Somatic Cell Genetics. 8, 6, p. 811-824 14 p.

研究成果: ジャーナルへの寄稿記事

Reproduction
Temperature
Methylnitronitrosoguanidine
Mutation
Cell Fusion