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研究成果 1990 2019

1998
113 引用 (Scopus)

Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human osteosarcoma

Oda, Y., Sakamoto, A., Shinohara, N., Ohga, T., Uchiumi, T., Kohno, K., Tsuneyoshi, M., Kuwano, M. & Iwamoto, Y., 9 1998, : : Clinical Cancer Research. 4, 9, p. 2273-2277 5 p.

研究成果: ジャーナルへの寄稿記事

P-Glycoprotein
Osteosarcoma
Proteins
Y-Box-Binding Protein 1
MDR Genes
46 引用 (Scopus)

The role of an inverted CCAAT element in transcriptional activation of the human DNA topoisomerase IIα gene by heat shock

Furukawa, M., Uchiumi, T., Nomoto, M., Takano, H., Morimoto, R. I., Naito, S., Kuwano, M. & Kohno, K., 4 24 1998, : : Journal of Biological Chemistry. 273, 17, p. 10550-10555 6 p.

研究成果: ジャーナルへの寄稿記事

Type II DNA Topoisomerase
Transcriptional Activation
Shock
Hot Temperature
Genes
1997
242 引用 (Scopus)

A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells

Koike, K., Kawabe, T., Tanaka, T., Toh, S., Uchiumi, T., Wada, M., Akiyama, S. I., Ono, M. & Kuwano, M., 12 15 1997, : : Cancer Research. 57, 24, p. 5475-5479 5 p.

研究成果: ジャーナルへの寄稿記事

Liver Neoplasms
Hepatocytes
Complementary DNA
Pharmaceutical Preparations
irinotecan
108 引用 (Scopus)

Cell cycle regulation of the human polo-like kinase (PLK) promoter

Uchiumi, T., Longo, D. L. & Ferris, D. K., 4 4 1997, : : Journal of Biological Chemistry. 272, 14, p. 9166-9174 9 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle
Phosphotransferases
Cells
Transcription Initiation Site
Luciferases
156 引用 (Scopus)

Nuclear translocation of the Y-box binding protein by ultraviolet irradiation

Koike, K., Uchiumi, T., Ohga, T., Toh, S., Wada, M., Kohno, K. & Kuwano, M., 11 17 1997, : : FEBS Letters. 417, 3, p. 390-394 5 p.

研究成果: ジャーナルへの寄稿記事

Green Fluorescent Proteins
Carrier Proteins
Irradiation
Cytosol
Y-Box-Binding Protein 1

Role of human MRP subfamily in drug resistance and other diseases

Wada, M., Uchiumi, T. & Kuwano, M., 1 1 1997, : : Nippon Nogeikagaku Kaishi. 71, 8, p. 793-798 6 p.

研究成果: ジャーナルへの寄稿記事

Chronic Idiopathic Jaundice
ABC transporters
ATP-Binding Cassette Transporters
drug resistance
Drug Resistance
3 引用 (Scopus)

The close association of π-class glutathione S-transferase with drug sensitivity to alkylating agents and cisplatin in human cancer cells

Tanaka, T., Yokomizo, A., Uchiumi, T., Furukawa, M., Wada, M. & Kuwano, M., 1 1 1997, : : International journal of oncology. 10, 5, p. 1009-1014 6 p.

研究成果: ジャーナルへの寄稿記事

Buthionine Sulfoximine
Alkylating Agents
Glutathione Transferase
Cisplatin
KB Cells
1994
68 引用 (Scopus)

Involvement of a dna binding protein, MDR-NF1/YB-1, in human MDR1 gene expression by actinomycin D

Asakuno, K., Kohno, K., Uchiumi, T., Kubo, T., Sato, S., Isono, M. & Kuwano, M., 3 30 1994, : : Biochemical and Biophysical Research Communications. 199, 3, p. 1428-1435 8 p.

研究成果: ジャーナルへの寄稿記事

MDR Genes
Chloramphenicol O-Acetyltransferase
Dactinomycin
Gene expression
Carrier Proteins
1993
31 引用 (Scopus)

Enhanced Expression of the DNA Topoisomerase II Gene in Response to Heat Shock Stress in Human Epidermoid Cancer KB Cells

Matsuo, K., Kohno, K., Sato, S., Uchiumi, T., Tanimura, H., Kuwano, M., amada, Y. & Kuwano, M., 3 1993, : : Cancer Research. 53, 5, p. 1085-1090 6 p.

研究成果: ジャーナルへの寄稿記事

KB Cells
Heat-Shock Response
Type II DNA Topoisomerase
Etoposide
Genes
136 引用 (Scopus)

Enhanced expression of the human multidrug resistance 1 gene in response to UV light irradiation.

Uchiumi, T., Kohno, K., Tanimura, H., Matsuo, K., Sato, S., Uchida, Y. & Kuwano, M., 3 1993, : : Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 4, 3, p. 147-157 11 p.

研究成果: ジャーナルへの寄稿記事

MDR Genes
Multiple Drug Resistance
Ultraviolet Rays
Chloramphenicol O-Acetyltransferase
Guanine
53 引用 (Scopus)

Involvement of protein kinase in environmental stress-induced activation of human multidrug resistance 1 (MDR1) gene promoter

Uchiumi, T., Kohno, K., Tanimura, H., Hidaka, K., Asakuno, K., Abe, H., Uchida, Y. & Kuwano, M., 7 1993, : : FEBS Letters. 326, 1-3, p. 11-16 6 p.

研究成果: ジャーナルへの寄稿記事

MDR Genes
Protein Kinases
Multiple Drug Resistance
Genes
Chemical activation
1992
83 引用 (Scopus)

Activation of human multidrug resistance-1 gene promoter in response to heat shock stress

Miyazaki, M., Kohno, K., Uchiumi, T., Tanimura, H., Matsuo, K. I., Nasu, M. & Kuwano, M., 9 16 1992, : : Biochemical and Biophysical Research Communications. 187, 2, p. 677-684 8 p.

研究成果: ジャーナルへの寄稿記事

MDR Genes
Heat-Shock Response
Hot Temperature
Genes
Shock
40 引用 (Scopus)

The human multidrug resistance 1 promoter has an element that responds to serum starvation

Tanimura, H., Kohno, K., Sato, S. I., Uchiumi, T., Miyazaki, M., Kobayashi, M. & Kuwano, M., 3 16 1992, : : Biochemical and Biophysical Research Communications. 183, 2, p. 917-924 8 p.

研究成果: ジャーナルへの寄稿記事

Chloramphenicol O-Acetyltransferase
Multiple Drug Resistance
Starvation
Genes
Cells
1991
6 引用 (Scopus)

Counteraction of estradiol‐induced activation of tissue‐type plasminogen activator in a human breast cancer cell line by an anti‐estrogen, LY117018

Uchiumi, T., Mizoguchi, H., Hagino, Y., Kohno, K. & Kuwano, M., 1 2 1991, : : International Journal of Cancer. 47, 1, p. 80-85 6 p.

研究成果: ジャーナルへの寄稿記事

LY 117018
Estrogen Receptor Modulators
Plasminogen Activators
MCF-7 Cells
Estradiol
1990
16 引用 (Scopus)

Enhanced production of tissue-type plasminogen activator by estradiol in a novel type variant of human breast cancer MCF-7 cell line

Mizoguchi, H., Uchiumi, T., Ono, M., Kohno, K. & Kuwano, M., 5 22 1990, : : BBA - Molecular Cell Research. 1052, 3, p. 475-482 8 p.

研究成果: ジャーナルへの寄稿記事

MCF-7 Cells
Tissue Plasminogen Activator
Estradiol
Breast Neoplasms
Cell Line
57 引用 (Scopus)

Tissue-specific enhancer of the human multidrug-resistance (MDR1) gene

Kohno, K., Sato, S., Uchiumi, T., Takano, H., Kato, S. & Kuwano, M., 12 17 1990, : : Journal of Biological Chemistry. 265, 32, p. 19690-19696 7 p.

研究成果: ジャーナルへの寄稿記事

Multiple Drug Resistance
Chloramphenicol O-Acetyltransferase
Genes
Tissue
5' Flanking Region