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研究成果 1994 2019

フィルター
評論記事
2019

Microglia-neuron interactions in the models of neuropathic pain

Saitoh, H. & Makoto, T., 11 1 2019, : : Biochemical Pharmacology. 169, 113614.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neurons
Chronic Pain
Chemical activation
2018
6 引用 (Scopus)

Astrocytes in the spinal dorsal horn and chronic itch

Makoto, T., 1 1 2018, : : Neuroscience Research. 126, p. 9-14 6 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Peripheral Nervous System
Central Nervous System
Skin

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Drug Discovery
Neuroglia
Hyperalgesia
Neuralgia
41 引用 (Scopus)

Microglia in neuropathic pain: Cellular and molecular mechanisms and therapeutic potential

Inoue, K. & Makoto, T., 2 16 2018, : : Nature Reviews Neuroscience. 19, 3, p. 138-152 15 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Chronic Pain
Nociceptive Pain
Peripheral Nerve Injuries
13 引用 (Scopus)

Modulation of Pain and Itch by Spinal Glia

Makoto, T., 2 1 2018, : : Neuroscience Bulletin. 34, 1, p. 178-185 8 p.

研究成果: ジャーナルへの寄稿評論記事

Neuroglia
Chronic Pain
Pain
Spinal Cord
Posterior Horn Cells
2017
37 引用 (Scopus)

Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex

Makoto, T., Koga, K., Chen, T. & Zhuo, M., 5 1 2017, : : Journal of Neurochemistry. 141, 4, p. 486-498 13 p.

研究成果: ジャーナルへの寄稿評論記事

Gyrus Cinguli
Neurology
Neuralgia
Chronic Pain
Pain
26 引用 (Scopus)

P2 receptors, microglial cytokines and chemokines, and neuropathic pain

Makoto, T., 6 1 2017, : : Journal of Neuroscience Research. 95, 6, p. 1319-1329 11 p.

研究成果: ジャーナルへの寄稿評論記事

Cytokine Receptors
Chemokine Receptors
Neuralgia
Microglia
Peripheral Nerve Injuries
5 引用 (Scopus)

Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension

Sunggip, C., Nishimura, A., Shimoda, K., Numaga-Tomita, T., Makoto, T. & Nishida, M., 6 1 2017, : : Pharmacological Research. 120, p. 51-59 9 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic Receptors
Hypertension
Angiotensin Type 1 Receptor
clopidogrel
Purinergic P2Y12 Receptors
17 引用 (Scopus)

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Nishimura, A., Sunggip, C., Oda, S., Numaga-Tomita, T., Makoto, T. & Nishida, M., 12 1 2017, : : Pharmacology and Therapeutics. 180, p. 113-128 16 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2Y Receptors
G-Protein-Coupled Receptors
Cardiovascular System
Cardiovascular Diseases
Uracil Nucleotides
3 引用 (Scopus)

Spinal dorsal horn astrocytes: New players in chronic itch

Tsuda, M., 1 1 2017, : : Allergology International. 66, 1, p. 31-35 5 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Skin
Spinal Cord Dorsal Horn
Therapeutics
2016
39 引用 (Scopus)

Neuron-microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration

Makoto, T. & Inoue, K., 5 1 2016, : : Neuropharmacology. 104, p. 76-81 6 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neurons
Purinergic P2Y Receptors
Purinergic P2X Receptors

New mechanism for chronic itch in the nervous system

Makoto, T. & Shiratori, M., 1 1 2016, : : Seikagaku. 88, 5, p. 654-656 3 p.

研究成果: ジャーナルへの寄稿評論記事

Neurology
Animals
Astrocytes
Atopic Dermatitis
2015
2 引用 (Scopus)
Neuralgia
Purinergic P2X4 Receptors
Neuroglia
Microglia
Peripheral Nerve Injuries
2013
77 引用 (Scopus)

Microglial regulation of neuropathic pain

Makoto, T., Masuda, T., Saitoh, H. & Inoue, K., 2 26 2013, : : Journal of Pharmacological Sciences. 121, 2, p. 89-94 6 p.

研究成果: ジャーナルへの寄稿評論記事

Neuralgia
Microglia
Wounds and Injuries
Posterior Horn Cells
Gene Expression
59 引用 (Scopus)

P2X4 receptors and neuropathic pain

Tsuda, M., Masuda, T., Tozaki-Saitoh, H. & Inoue, K., 10 28 2013, : : Frontiers in Cellular Neuroscience. OCT, 191.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2X4 Receptors
Microglia
Neuralgia
Chemokine CCL21
CCR Receptors
2012
8 引用 (Scopus)

P2Y receptors in microglia and neuroinflammation

Saitoh, H., Makoto, T. & Inoue, K., 7 1 2012, : : Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1, 4, p. 493-501 9 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Central Nervous System
Purinergic Receptors
Cytophagocytosis
Uridine Diphosphate
40 引用 (Scopus)

Purinergic system, microglia and neuropathic pain

Makoto, T., Saitoh, H. & Inoue, K., 2 1 2012, : : Current Opinion in Pharmacology. 12, 1, p. 74-79 6 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Purinergic Receptors
Peripheral Nerve Injuries
Neuroglia
47 引用 (Scopus)

Purinergic systems, neuropathic pain and the role of microglia

Inoue, K. & Makoto, T., 4 1 2012, : : Experimental Neurology. 234, 2, p. 293-301 9 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic Receptors
Microglia
Neuralgia
Purinergic P2Y12 Receptors
Purinergic P2X4 Receptors
9 引用 (Scopus)

Role of the glia in neuropathic pain caused by peripheral nerve injury

Inoue, K., Makoto, T. & Saitoh, H., 11 2012, : : Brain and Nerve. 64, 11, p. 1233-1239 7 p.

研究成果: ジャーナルへの寄稿評論記事

Peripheral Nerve Injuries
Neuralgia
Neuroglia
Microglia
Astrocytes
2011
14 引用 (Scopus)

Platelet-activating factor and pain

Makoto, T., Saitoh, H. & Inoue, K., 8 1 2011, : : Biological and Pharmaceutical Bulletin. 34, 8, p. 1159-1162 4 p.

研究成果: ジャーナルへの寄稿評論記事

Platelet Activating Factor
Pain
Neuralgia
Spinal Ganglia
Wounds and Injuries
2010
91 引用 (Scopus)

Pain and purinergic signaling

Makoto, T., Saitoh, H. & Inoue, K., 5 1 2010, : : Brain Research Reviews. 63, 1-2, p. 222-232 11 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Microglia
Peripheral Nerve Injuries
Nucleotides
Second Messenger Systems
1 引用 (Scopus)

Purinergic regulation of microglia

Saitoh, H., Makoto, T. & Inoue, K., 10 12 2010, : : Folia Pharmacologica Japonica. 136, 2, p. 93-97 5 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2Y12 Receptors
Purinergic P2X4 Receptors
Purinergic P2X7 Receptors
Purinergic P2 Receptors
Microglia
2009
184 引用 (Scopus)

Microglia and neuropathic pain

Inoue, K. & Makoto, T., 11 27 2009, : : GLIA. 57, 14, p. 1469-1479 11 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Pain
Wounds and Injuries
Posterior Horn Cells

Role of extracellular nucleotides and their receptors in chronic pain

Makoto, T. & Inoue, K., 10 1 2009, : : Seikagaku. 81, 10, p. 884-890 7 p.

研究成果: ジャーナルへの寄稿評論記事

Symporters
Purinergic P2 Receptors
Signal transduction
Drug Design
Brain-Derived Neurotrophic Factor
2007
23 引用 (Scopus)

Modification of neuropathic pain sensation through microglial ATP receptors

Inoue, K., Makoto, T. & Saitoh, H., 9 1 2007, : : Purinergic Signalling. 3, 4, p. 311-316 6 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Neuralgia
Microglia
Peripheral Nerves
Neuroglia
5 引用 (Scopus)

Neuropathic pain and ATP receptors in spinal microglia

Makoto, T. & Inoue, K., 9 2007, : : Brain and Nerve. 59, 9, p. 953-959 7 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Nociceptors
Microglia
Neuralgia
Purinergic P2X4 Receptors
83 引用 (Scopus)

The role of nucleotides in the neuron-glia communication responsible for the brain functions

Inoue, K., Koizumi, S. & Makoto, T., 9 1 2007, : : Journal of Neurochemistry. 102, 5, p. 1447-1458 12 p.

研究成果: ジャーナルへの寄稿評論記事

Neuroglia
Neurons
Brain
Nucleotides
Microglia
2006

Role of molecules expressed in spiral microglia in neuropathic pain

Tsuda, M. & Inoue, K., 2 2006, : : Japanese Journal of Psychopharmacology. 26, 1, p. 57-61 5 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Pain
Purinergic P2X4 Receptors
Peripheral Nerves
15 引用 (Scopus)

The role of microglia and ATP receptors in a mechanism of neuropathic pain

Inoue, K. & Makoto, T., 12 1 2006, : : Folia Pharmacologica Japonica. 127, 1, p. 14-17 4 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Microglia
Neuralgia
Pain
2005
25 引用 (Scopus)

ATP receptors in pain sensation: Involvement of spinal microglia and P2X4 receptors

Inoue, K., Makoto, T. & Koizumi, S., 6 1 2005, : : Purinergic Signalling. 1, 2, p. 95-100 6 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2X4 Receptors
Purinergic P2 Receptors
Microglia
Neuralgia
Pain
584 引用 (Scopus)

Neuropathic pain and spinal microglia: A big problem from molecules in 'small' glia

Makoto, T., Inoue, K. & Salter, M. W., 2 1 2005, : : Trends in Neurosciences. 28, 2, p. 101-107 7 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neuroglia
Pain
Wounds and Injuries
2004
1 引用 (Scopus)

ATP and neuropathic pain

Inoue, K., Makoto, T. & Koizumi, S., 1 1 2004, : : Seikagaku. The Journal of Japanese Biochemical Society. 76, 11, p. 1431-1439 9 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Signal transduction
Uridine Triphosphate
Gene expression
Animals
1 引用 (Scopus)

ATP receptors in pain sensation

Inoue, K., Makoto, T. & Koizumi, S., 11 8 2004, : : Folia Pharmacologica Japonica. 124, 4, p. 228-233 6 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Hyperalgesia
Pain
Unmyelinated Nerve Fibers
Diagnosis-Related Groups
2000
1 引用 (Scopus)

ATP receptors in pain

Makoto, T., Koizumi, S. & Inoue, K., 1 1 2000, : : Folia Pharmacologica Japonica. 116, 6, p. 343-350 8 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2X3 Receptors
Purinergic P2 Receptors
Capsaicin
Hyperalgesia
Purinergic P2X2 Receptors
1999
10 引用 (Scopus)

Contribution of glutamate receptors to benzodiazepine withdrawal signs

Makoto, T., Shimizu, N. & Suzuki, T., 10 23 1999, : : Japanese Journal of Pharmacology. 81, 1, p. 1-6 6 p.

研究成果: ジャーナルへの寄稿評論記事

Glutamate Receptors
Diazepam
Benzodiazepines
D-Aspartic Acid
Lorazepam
26 引用 (Scopus)

The functions of ATP receptors in the synaptic transmission in the hippocampus

Inoue, K., Koizumi, S., Ueno, S., Kita, A. & Makoto, T., 1 1 1999, : : Progress in Brain Research. 120, p. 193-206 14 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Synaptic Transmission
Hippocampus
1998

Signal transduction through ATP receptors in brain and the development of new drugs

Inoue, K., Koizumi, S., Ueno, S. & Makoto, T., 1 1 1998, : : Nippon yakurigaku zasshi. Folia pharmacologica Japonica. 112 Suppl 1

研究成果: ジャーナルへの寄稿評論記事

Signal Transduction
Adenosine Triphosphate
Brain
Pharmaceutical Preparations
Hippocampus