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研究成果 2010 2019

2019
1 引用 (Scopus)

Association between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study

Inaishi, J., Hirakawa, Y., Horikoshi, M., Akiyama, M., Higashioka, M., Yoshinari, M., Hata, J., Mukai, N., Kamatani, Y., Momozawa, Y., Kubo, M. & Ninomiya, T., 6 19 2019, : : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3213-3222 10 p.

研究成果: ジャーナルへの寄稿記事

Medical problems
Type 2 Diabetes Mellitus
Population
Hazards
Precision Medicine
1 引用 (Scopus)

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE), 5 21 2019, : : Circulation. 139, 21, p. 2422-2436 15 p.

研究成果: ジャーナルへの寄稿記事

Omega-6 Fatty Acids
Linoleic Acid
Cardiovascular Diseases
Biomarkers
Arachidonic Acid

Coffee drinking and risk of all-cause mortality and cardiovascular diseases

Hirakawa, Y., 4 1 2019, : : Circulation Journal. 83, 4, p. 711-712 2 p.

研究成果: ジャーナルへの寄稿編集

公開
Coffee
Drinking
Cardiovascular Diseases
Mortality
Activities of Daily Living
Population
Independent Living
Geriatrics
Mental Competency
3 引用 (Scopus)

Effects of blood pressure lowering on cardiovascular events, in the context of regression to the mean: a systematic review of randomized trials

Blood Pressure Lowering Treatment Trialists’ Collaboration, 1 1 2019, : : Journal of hypertension. 37, 1, p. 16-23 8 p.

研究成果: ジャーナルへの寄稿記事

Blood Pressure
Coronary Disease
Stroke
Therapeutics
MEDLINE

Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General Japanese Population: The Hisayama Study

Fujiwara, K., Yasuda, M., Hata, J., Hirakawa, Y., Hashimoto, S., Ueda, E., Iwase, A., Araie, M., Yoshitomi, T., Ninomiya, T. & Sonoda, K., 9 1 2019, : : American journal of ophthalmology. 205, p. 140-146 7 p.

研究成果: ジャーナルへの寄稿記事

Nerve Fibers
Glucose
Population
Prediabetic State
Glucose Intolerance
3 引用 (Scopus)

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

ENCHANTED Investigators and Coordinators, 3 2 2019, : : The Lancet. 393, 10174, p. 877-888 12 p.

研究成果: ジャーナルへの寄稿記事

Stroke
Blood Pressure
Tissue Plasminogen Activator
Guidelines
Therapeutics
Exercise
Population
Independent Living
Japan
Light

Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations

Matsuno, Y., Umeno, J., Esaki, M., Hirakawa, Y., Fuyuno, Y., Okamoto, Y., Hirano, A., Yasukawa, S., Hirai, F., Matsui, T., Hosomi, S., Watanabe, K., Hosoe, N., Ogata, H., Hisamatsu, T., Yanai, S., Kochi, S., Kurahara, K., Yao, T., torisu, T. および2人, Kitazono, T. & Matsumoto, T., 1 1 2019, : : World Journal of Gastroenterology. 25, 14, p. 1753-1763 11 p.

研究成果: ジャーナルへの寄稿記事

公開
Prostaglandins
Crohn Disease
Prostaglandins E
Genes
ROC Curve
公開
Diabetes Mellitus
Insulin Resistance
Population
Homeostasis
Energy Intake
1 引用 (Scopus)

Physical component quality of life reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 quality of life: An AusDiab analysis

Wong, M. G., Ninomiya, T., Liyanage, T., Sukkar, L., Hirakawa, Y., Wang, Y., Wyld, M. L. R., Morton, R. L., Chadban, S., Howard, K. & Jardine, M. J., 6 1 2019, : : Nephrology. 24, 6, p. 605-614 10 p.

研究成果: ジャーナルへの寄稿記事

Glomerular Filtration Rate
Chronic Renal Insufficiency
Albuminuria
Quality of Life
Social Adjustment
1 引用 (Scopus)

Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study

Ohara, T., Hata, J., Tanaka, M., Honda, T., Yamakage, H., Yoshida, D., Inoue, T., Hirakawa, Y., Kusakabe, T., Shibata, M., Teraoka, T., Kitazono, T., Kanba, S., Satoh-Asahara, N. & Ninomiya, T., 1 1 2019, : : Annals of Neurology. 85, 1, p. 47-58 12 p.

研究成果: ジャーナルへの寄稿記事

Myeloid Cells
Dementia
Biomarkers
Alzheimer Disease
Vascular Dementia
公開
Cross-Sectional Studies
Smoking
Population
Japan
Environmental Pollution
1 引用 (Scopus)
Prediabetic State
Type 2 Diabetes Mellitus
Body Mass Index
Glucose Tolerance Test
Obesity
2018
3 引用 (Scopus)
Independent Living
Vascular Dementia
Albuminuria
Alzheimer Disease
Glomerular Filtration Rate
Myeloid Cells
Insulin Resistance
Serum
Population
Fats
2 引用 (Scopus)
Dementia
Sleep
Mortality
Hypnotics and Sedatives
Confidence Intervals
2 引用 (Scopus)

Development and validation of a risk assessment tool for gastric cancer in a general Japanese population

Iida, M., Ikeda, F., Hata, J., Hirakawa, Y., Ohara, T., Mukai, N., Yoshida, D., Yonemoto, K., Esaki, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 5 1 2018, : : Gastric Cancer. 21, 3, p. 383-390 8 p.

研究成果: ジャーナルへの寄稿記事

Stomach Neoplasms
Population
Pepsinogen A
Proportional Hazards Models
Helicobacter pylori
Cardiovascular Diseases
Decision Support Techniques
Coronary Disease
Stroke
Blood Pressure
1 引用 (Scopus)

Insulin and glucose-lowering agents for treating people with diabetes and chronic kidney disease

Lo, C., Toyama, T., Wang, Y., Lin, J., Hirakawa, Y., Jun, M., Cass, A., Hawley, C. M., Pilmore, H., Badve, S. V., Perkovic, V. & Zoungas, S., 9 24 2018, : : Cochrane Database of Systematic Reviews. 2018, 9, CD011798.

研究成果: ジャーナルへの寄稿評論記事

Sodium-Glucose Transporter 2
Chronic Renal Insufficiency
Symporters
Dipeptidyl-Peptidase IV Inhibitors
Placebos
4 引用 (Scopus)

Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community

Yubi, T., Hata, J., Ohara, T., Mukai, N., Hirakawa, Y., Yoshida, D., Gotoh, S., Hirabayashi, N., Furuta, Y., Ago, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 6 1 2018, : : Neurology: Clinical Practice. 8, 3, p. 223-231 9 p.

研究成果: ジャーナルへの寄稿評論記事

Cross-Sectional Studies
Logistic Models
Cholesterol
Regression Analysis
Hypertension
1 引用 (Scopus)

Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: The Hisayama Study

Furuta, Y., Hata, J., Mukai, N., Hirakawa, Y., Ago, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 6 1 2018, : : Atherosclerosis. 273, p. 84-90 7 p.

研究成果: ジャーナルへの寄稿記事

Transient Ischemic Attack
Japan
Incidence
Stroke
Blood Pressure
2017
9 引用 (Scopus)

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN)

the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), 1 1 2017, : : Journal of Epidemiology. 27, 3, p. 123-129 7 p.

研究成果: ジャーナルへの寄稿記事

Diabetes Mellitus
Japan
Cardiovascular Diseases
Mortality
Research
4 引用 (Scopus)
Hyperglycemia
Alzheimer Disease
Hemoglobins
Glycosylated Hemoglobin A
Hazards
5 引用 (Scopus)
Vitamin D
Cause of Death
Respiratory Tract Infections
Cardiovascular Infections
Serum
2 引用 (Scopus)

Cumulative in-trial and post-trial effects of blood pressure and lipid lowering: Systematic review and meta-analysis

Hirakawa, Y., Arima, H., Rodgers, A., Woodward, M. & Chalmers, J., 1 1 2017, : : Journal of Hypertension. 35, 5, p. 905-913 9 p.

研究成果: ジャーナルへの寄稿評論記事

Meta-Analysis
Blood Pressure
Lipids
Mortality
Hydroxymethylglutaryl-CoA Reductase Inhibitors
7 引用 (Scopus)

Development of an Australian cardiovascular disease mortality risk score using multiple imputation and recalibration from national statistics

Backholer, K., Hirakawa, Y., Tonkin, A., Giles, G., Magliano, D. J., Colagiuri, S., Harris, M., Mitchell, P., Nelson, M., Shaw, J. E., Simmons, D., Simons, L., Taylor, A., Harding, J., Gopinath, B. & Woodward, M., 1 6 2017, : : BMC Cardiovascular Disorders. 17, 1, 17.

研究成果: ジャーナルへの寄稿記事

Cardiovascular Diseases
Mortality
Blood Pressure
HDL Cholesterol
Smoking
5 引用 (Scopus)
Chronic Renal Insufficiency
Cardiovascular Diseases
Coronary Disease
Serum
Confidence Intervals
2 引用 (Scopus)

Side effects and tolerability of combination blood pressure lowering according to blood pressure levels: An analysis of the PROGRESS and ADVANCEtrials

Atkins, E. R., Hirakawa, Y., Salam, A., Woodward, M., Cooper, M., Hamet, P., Harrap, S., Lees, K., Liu, L., Mancia, G., Marre, M., Perkovic, V., Poulter, N., Williams, B., Chalmers, J. & Rodgers, A., 1 1 2017, : : Journal of hypertension. 35, 6, p. 1318-1325 8 p.

研究成果: ジャーナルへの寄稿記事

Blood Pressure
Hypotension
Therapeutics
Kidney
perindopril drug combination indapamide
1 引用 (Scopus)

The gene-treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry

Sumi, A., Nakamura, U., Iwase, M., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Komorita, Y., Yoshinari, M., Hirakawa, Y., Hirano, A., Kubo, M. & Kitazono, T., 12 12 2017, : : BMC Medical Genetics. 18, 1, 146.

研究成果: ジャーナルへの寄稿記事

Aryldialkylphosphatase
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Type 2 Diabetes Mellitus
Registries
Insulin
1 引用 (Scopus)

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: The Hisayama Study

Nagata, M., Hata, J., Hirakawa, Y., Mukai, N., Yoshida, D., Ohara, T., Kishimoto, H., Kawano, H., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 1 1 2017, : : Journal of epidemiology. 27, 12, p. 578-583 6 p.

研究成果: ジャーナルへの寄稿記事

Eicosapentaenoic Acid
Arachidonic Acid
Serum
Neoplasms
Independent Living
2 引用 (Scopus)

White-coat and masked hypertension are associated with albuminuria in a general population: The Hisayama Study

Hata, J., Fukuhara, M., Sakata, S., Arima, H., Hirakawa, Y., Yonemoto, K., Mukai, N., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 11 1 2017, : : Hypertension Research. 40, 11, p. 937-943 7 p.

研究成果: ジャーナルへの寄稿記事

Masked Hypertension
White Coat Hypertension
Albuminuria
Hypertension
Population
2016
7 引用 (Scopus)

Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies

Qiu, M., Sato, S., Zheng, D., Wang, X., Carcel, C., Hirakawa, Y., Sandset, E. C., Delcourt, C., Arima, H., Wang, J., Chalmers, J. & Anderson, C. S., 6 1 2016, : : Stroke. 47, 6, p. 1479-1485 7 p.

研究成果: ジャーナルへの寄稿記事

Cerebral Hemorrhage
Heart Rate
Blood Pressure
Hematoma
Mortality
15 引用 (Scopus)

Combination of helicobacter pylori antibody and serum pepsinogen as a good predictive tool of gastric cancer incidence: 20-year prospective data from the hisayama study

Ikeda, F., Shikata, K., Hata, J., Fukuhara, M., Hirakawa, Y., Ohara, T., Mukai, N., Nagata, M., Yoshida, D., Yonemoto, K., Esaki, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 1 1 2016, : : Journal of epidemiology. 26, 12, p. 629-636 8 p.

研究成果: ジャーナルへの寄稿記事

Pepsinogen A
Helicobacter pylori
Stomach Neoplasms
Antibodies
Incidence
6 引用 (Scopus)

Depression but not anxiety predicts recurrent cerebrovascular events

Yu, S., Arima, H., Bertmar, C., Hirakawa, Y., Priglinger, M., Evans, K. & Krause, M., 7 1 2016, : : Acta Neurologica Scandinavica. 134, 1, p. 29-34 6 p.

研究成果: ジャーナルへの寄稿記事

Anxiety
Stroke
Depression
Transient Ischemic Attack
Logistic Models
11 引用 (Scopus)

Effects of smoking and its cessation on creatinine- and cystatin C-based estimated glomerular filtration rates and albuminuria in male patients with type 2 diabetes mellitus: The Fukuoka Diabetes Registry

Ohkuma, T., Nakamura, U., Iwase, M., Ide, H., Fujii, H., Jodai, T., Kaizu, S., Kikuchi, Y., Idewaki, Y., Sumi, A., Hirakawa, Y. & Kitazono, T., 10 1 2016, : : Hypertension Research. 39, 10, p. 744-751 8 p.

研究成果: ジャーナルへの寄稿記事

Cystatin C
Albuminuria
Smoking Cessation
Glomerular Filtration Rate
Type 2 Diabetes Mellitus
2 引用 (Scopus)

Foveal and Macular Thickness in a Japanese Population: The Hisayama Study

Hashimoto, S., Yasuda, M., Ninomiya, T., Hata, J., Yoshida, D., Tahara-Asakuma, T., Hirakawa, Y., Arakawa, S., Fujiwara, K., Kiyohara, Y. & Ishibashi, T., 5 3 2016, : : Ophthalmic Epidemiology. 23, 3, p. 202-208 7 p.

研究成果: ジャーナルへの寄稿記事

Refractive Errors
Body Height
Smoking
Population
Regression Analysis
21 引用 (Scopus)

Microvascular and macrovascular disease and risk for major peripheral arterial disease in patients with type 2 diabetes

Mohammedi, K., Woodward, M., Hirakawa, Y., Zoungas, S., Williams, B., Lisheng, L., Rodgers, A., Mancia, G., Neal, B., Harrap, S., Marre, M. & Chalmers, J., 10 1 2016, : : Diabetes care. 39, 10, p. 1796-1803 8 p.

研究成果: ジャーナルへの寄稿記事

Peripheral Arterial Disease
Type 2 Diabetes Mellitus
perindopril drug combination indapamide
Light Coagulation
Vascular Diseases
10 引用 (Scopus)

Prediction of 10-year vascular risk in patients with diabetes: The AD-ON risk score

on behalf of the ADVANCE Collaborative Group, 3 1 2016, : : Diabetes, Obesity and Metabolism. 18, 3, p. 289-294 6 p.

研究成果: ジャーナルへの寄稿記事

Blood Vessels
perindopril drug combination indapamide
Kidney
Gliclazide
Random Allocation
24 引用 (Scopus)

Presentations of major peripheral arterial disease and risk of major outcomes in patients with type 2 diabetes: Results from the ADVANCE-ON study

Mohammedi, K., Woodward, M., Hirakawa, Y., Zoungas, S., Colagiuri, S., Hamet, P., Harrap, S., Poulter, N., Matthews, D. R., Marre, M. & Chalmers, J., 9 2 2016, : : Cardiovascular Diabetology. 15, 1, 129.

研究成果: ジャーナルへの寄稿記事

Peripheral Arterial Disease
Type 2 Diabetes Mellitus
Amputation
Lower Extremity
perindopril drug combination indapamide
19 引用 (Scopus)

Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes

Hirakawa, Y., Arima, H., Webster, R., Zoungas, S., Li, Q., Harrap, S., Lisheng, L., Hamet, P., Mancia, G., Poulter, N., Neal, B., Williams, B., Rogers, A., Woodward, M. & Chalmers, J., 4 1 2016, : : Journal of hypertension. 34, 4, p. 781-787 7 p.

研究成果: ジャーナルへの寄稿記事

Type 2 Diabetes Mellitus
Blood Pressure
perindopril drug combination indapamide
Placebos
Indapamide
10 引用 (Scopus)

Serum Angiopoietin-Like Protein 2 Is a Novel Risk Factor for Cardiovascular Disease in the Community

Hata, J., Mukai, N., Nagata, M., Ohara, T., Yoshida, D., Kishimoto, H., Shibata, M., Hirakawa, Y., Endo, M., Ago, T., Kitazono, T., Oike, Y., Kiyohara, Y. & Ninomiya, T., 8 1 2016, : : Arteriosclerosis, thrombosis, and vascular biology. 36, 8, p. 1686-1691 6 p.

研究成果: ジャーナルへの寄稿記事

Angiopoietins
Cardiovascular Diseases
Serum
Proteins
Confidence Intervals
19 引用 (Scopus)

Serum uric acid as a risk factor for chronic kidney disease in a Japanese community-the hisayama study

Takae, K., Nagata, M., Hata, J., Mukai, N., Hirakawa, Y., Yoshida, D., Kishimoto, H., Tsuruya, K., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 1 1 2016, : : Circulation Journal. 80, 8, p. 1857-1862 6 p.

研究成果: ジャーナルへの寄稿記事

Uric Acid
Chronic Renal Insufficiency
Albuminuria
Serum
Kidney
5 引用 (Scopus)

The impact of body mass index on the associations of lipids with the risk of coronary heart disease in the Asia Pacific region

on behalf of the Asia Pacific Cohort Studies Collaboration, 6 1 2016, : : Preventive Medicine Reports. 3, p. 79-82 4 p.

研究成果: ジャーナルへの寄稿記事

Coronary Disease
Body Mass Index
HDL Cholesterol
Lipids
Cholesterol
2015
19 引用 (Scopus)

Age-and sex-specific burden of cardiovascular disease attributable to 5 major and modifiable risk factors in 10 asian countries of the western pacific region

Huxley, R. R., Hirakawa, Y., Hussain, M. A., Aekplakorn, W., Wang, X., Peters, S. A., Mamun, A. & Woodward, M., 7 24 2015, : : Circulation Journal. 79, 8, p. 1662-1674 13 p.

研究成果: ジャーナルへの寄稿記事

Cardiovascular Diseases
Vascular Diseases
Resource Allocation
Health Policy
Sex Characteristics
48 引用 (Scopus)

Association between eating rate and obesity: A systematic review and meta-analysis

Ohkuma, T., Hirakawa, Y., Nakamura, U., Kiyohara, Y., Kitazono, T. & Ninomiya, T., 1 1 2015, : : International Journal of Obesity. 39, 11, p. 1589-1596 8 p.

研究成果: ジャーナルへの寄稿評論記事

Meta-Analysis
Obesity
Eating
Body Mass Index
Confidence Intervals
16 引用 (Scopus)

Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: The Hisayama Study

Mukai, N., Ninomiya, T., Hata, J., Hirakawa, Y., Ikeda, F., Fukuhara, M., Hotta, T., Koga, M., Nakamura, U., Kang, D., Kitazono, T. & Kiyohara, Y., 6 24 2015, : : Cardiovascular Diabetology. 14, 1, 84.

研究成果: ジャーナルへの寄稿記事

Independent Living
Carotid Artery Diseases
Hemoglobins
Glucose
Glucose Intolerance
21 引用 (Scopus)

Dose- and time-dependent association of smoking and its cessation with glycemic control and insulin resistance in male patients with type 2 diabetes mellitus: The Fukuoka diabetes registry

Ohkuma, T., Iwase, M., Fujii, H., Kaizu, S., Ide, H., Jodai, T., Kikuchi, Y., Idewaki, Y., Hirakawa, Y., Nakamura, U. & Kitazono, T., 3 30 2015, : : PLoS One. 10, 3, e0122023.

研究成果: ジャーナルへの寄稿記事

glycemic control
Smoking Cessation
Medical problems
noninsulin-dependent diabetes mellitus
insulin resistance
perindopril drug combination indapamide
Indapamide
Gliclazide
Perindopril
Calcium Channel Blockers
10 引用 (Scopus)

Health-related quality of life in survivors of acute kidney injury: The Prolonged Outcomes Study of the Randomized Evaluation of Normal versus Augmented Level Replacement Therapy study outcomes

Wang, A. Y., Bellomo, R., Cass, A., Finfer, S., Gattas, D., Myburgh, J., Chadban, S., Hirakawa, Y., Ninomiya, T., Li, Q., Lo, S., Barzi, F., Sukkar, L., Jardine, M. & Gallagher, M. P., 1 1 2015, : : Nephrology. 20, 7, p. 492-498 7 p.

研究成果: ジャーナルへの寄稿記事

Acute Kidney Injury
Survivors
Quality of Life
Outcome Assessment (Health Care)
Kidney