Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2019

2010

Protease-triggered targeted delivery of gold nanorods into tumor

Niidome, T., Ohga, A., Ando, T., Niidome, Y., Mori, T. & Katayama, Y., 2010, Biological Imaging and Sensing Using Nanoparticle Assemblies. 巻 1241. p. 84-88 5 p.

研究成果: 著書/レポートタイプへの貢献会議での発言

protease
Nanorods
Gold
nanorods
Tumors
15 引用 (Scopus)

Protein kinase substrate profiling with a high-density peptide microarray

Han, X., Sonoda, T., Mori, T., Yamanouchi, G., Yamaji, T., Shigaki, S., Niidome, T. & Katayama, Y., 11 1 2010, : : Combinatorial Chemistry and High Throughput Screening. 13, 9, p. 777-789 13 p.

研究成果: ジャーナルへの寄稿記事

Microarrays
Protein Kinases
Peptides
Proteins
Substrates
14 引用 (Scopus)

Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator

Asai, D., Kuramoto, M., Shoji, Y., Kang, J. H., Kodama, K. B., Kawamura, K., Mori, T., Miyoshi, H., Niidome, T., Nakashima, H. & Katayama, Y., 1 4 2010, : : Journal of Controlled Release. 141, 1, p. 52-61 10 p.

研究成果: ジャーナルへの寄稿記事

Transgenes
Peptide Hydrolases
HIV
Peptides
Picornaviridae
5 引用 (Scopus)

Targeted delivery of gold nanorods modified with thermo-sensitive polymer.

Niidome, T., Shiotani, A., Mori, T. & Katayama, Y., 11 20 2010, : : Journal of Controlled Release. 148, 1

研究成果: ジャーナルへの寄稿記事

Acrylic Resins
Nanotubes
Drug Delivery Systems
Gold
Polymers

The combination of drug or gene delivery system responding to cellular signals (D-RECS) and sonoporation system for effective and safe gene delivery

Tsuchiya, A., Mori, T., Naritomi, Y., Kang, J. H., Asai, D., Niidome, T., Endo, Y., Suzuki, R., Negishi, Y., Maruyama, K. & Katayama, Y., 12 1 2010, Nanobiotechnology and Nanobiophotonics - Opportunities and Challenges. p. 7-11 5 p. (Materials Research Society Symposium Proceedings; 巻数 1237).

研究成果: 著書/レポートタイプへの貢献会議での発言

gene expression
Drug Combinations
Gene expression
genes
delivery

The effect of PEG grafted on gold nanorods and their injection dose on biodistribution in tumor-bearing mice

Akiyama, Y., Mori, T., Katayama, Y. & Niidome, T., 10 15 2010, Biological Imaging and Sensing Using Nanoparticle Assemblies. p. 33-38 6 p. (Materials Research Society Symposium Proceedings; 巻数 1241).

研究成果: 著書/レポートタイプへの貢献会議での発言

Bearings (structural)
Nanorods
Gold
Polyethylene glycols
nanorods
10 引用 (Scopus)

Tumor therapy by gene regulation system responding to cellular signal

Tomiyama, T., Toita, R., Kang, J. H., Asai, D., Shiosaki, S., Mori, T., Niidome, T. & Katayama, Y., 11 20 2010, : : Journal of Controlled Release. 148, 1, p. 101-105 5 p.

研究成果: ジャーナルへの寄稿記事

Genetic Therapy
Protein Kinase C
Neoplasms
Gene Transfer Techniques
Polymers
16 引用 (Scopus)

Unusually Large Hysteresis of Temperature-Responsive Poly(N-ethyl-2- propionamidoacrylamide) Studied by Microcalorimetry and FT-IR

Berber, M. R., Mori, H., Hafez, I. H., Minagawa, K., Tanaka, M., Niidome, T., Katayama, Y., Maruyama, A., Hirano, T., Maeda, Y. & Mori, T., 6 17 2010, : : Journal of Physical Chemistry B. 114, 23, p. 7784-7790 7 p.

研究成果: ジャーナルへの寄稿記事

Phase Transition
Hysteresis
Transition Temperature
hysteresis
Temperature
2009
8 引用 (Scopus)

A novel protease activity assay using a protease-responsive chaperone protein

Sao, K., Murata, M., Fujisaki, Y., Umezaki, K., Mori, T., Niidome, T., Katayama, Y. & Hashizume, M., 6 5 2009, : : Biochemical and Biophysical Research Communications. 383, 3, p. 293-297 5 p.

研究成果: ジャーナルへの寄稿記事

Assays
Peptide Hydrolases
Proteins
Factor Xa
Small Heat-Shock Proteins
7 引用 (Scopus)

A syngeneic hepatocellular carcinoma model rapidly and simply prepared using a hydrodynamics-based procedure

Kang, J. H., Mori, T., Niidome, T. & Katayama, Y., 9 1 2009, : : Veterinary Journal. 181, 3, p. 336-339 4 p.

研究成果: ジャーナルへの寄稿記事

hepatoma
Hydrodynamics
hydrodynamics
Hepatocellular Carcinoma
liver neoplasms
4 引用 (Scopus)

Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals

Kang, J. H., Toita, R., Tomiyama, T., Oishi, J., Asai, D., Mori, T., Niidome, T. & Katayama, Y., 11 1 2009, : : Bioorganic and Medicinal Chemistry Letters. 19, 21, p. 6082-6086 5 p.

研究成果: ジャーナルへの寄稿記事

Gene Transfer Techniques
Essential Genes
Protein Sorting Signals
Genes
Protein Kinase C
3 引用 (Scopus)

Establishment of screening system toward discovery of kinase inhibitors using label-free on-chip phosphorylation assays

Inamori, K., Kyo, M., Matsukawa, K., Inoue, Y., Sonoda, T., Mori, T., Niidome, T. & Katayama, Y., 9 1 2009, : : BioSystems. 97, 3, p. 179-185 7 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Amides
Inhibitor
Screening
Labels
1 引用 (Scopus)

Gene transfer into cells from solid surfaces and its application to in vivo systems

Niidome, T., Yakumaru, K., Shiotani, A., Yamashita, S. & Katayama, Y., 7 20 2009, : : Chemistry Letters. 38, 1, p. 36-37 2 p.

研究成果: ジャーナルへの寄稿記事

Gene transfer
Genes
Glass
Stents
DNA
3 引用 (Scopus)

Improvement of peptide vectors for gene delivery with active targeting profiles for phosphatidylserine

Kuriyama, S., Taguchi, Y., Nishimura, K., Yanagibashi, K., Katayama, Y. & Niidoime, T., 6 1 2009, : : Journal of Peptide Science. 15, 2, p. 114-119 6 p.

研究成果: ジャーナルへの寄稿記事

Phosphatidylserines
Genes
Peptides
Transfection
Tumors
19 引用 (Scopus)

Inflammatory cell-specific transgene expression system responding to Iκ-B kinase beta activation

Asai, D., Tsuchiya, A., Kang, J. H., Kawamura, K., Oishi, J., Mori, T., Niidome, T., Shoji, Y., Nakashima, H. & Katayama, Y., 10 2 2009, : : Journal of Gene Medicine. 11, 7, p. 624-632 9 p.

研究成果: ジャーナルへの寄稿記事

Transgenes
Polymers
Phosphotransferases
DNA
Gene Expression

In vivo monitoring of gold nanorods and tissue damage mediated with their photothermal effect

Niidome, T., Akiyama, Y., Shimoda, K., Kawano, T., Mori, T., Katayama, Y. & Niidome, Y., 12 1 2009, Nanofunctional Materials, Structures, and Devices for Biomedical Applications. p. 73-78 6 p. (Materials Research Society Symposium Proceedings; 巻数 1138).

研究成果: 著書/レポートタイプへの貢献会議での発言

Nanorods
Gold
nanorods
Tissue
gold
66 引用 (Scopus)

In vivo siRNA delivery with dendritic poly(l-lysine) for the treatment of hypercholesterolemia

Watanabe, K., Harada-Shiba, M., Suzuki, A., Gokuden, R., Kurihara, R., Sugao, Y., Mori, T., Katayama, Y. & Niidome, T., 10 19 2009, : : Molecular BioSystems. 5, 11, p. 1306-1310 5 p.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins B
Hypercholesterolemia
Small Interfering RNA
Lysine
Apolipoproteins E
18 引用 (Scopus)

Molecular design of protein-based nanocapsules for stimulus-responsive characteristics

Sao, K., Murata, M., Umezaki, K., Fujisaki, Y., Mori, T., Niidome, T., Katayama, Y. & Hashizume, M., 1 1 2009, : : Bioorganic and Medicinal Chemistry. 17, 1, p. 85-93 9 p.

研究成果: ジャーナルへの寄稿記事

Nanocapsules
Proteins
Factor Xa
Peptide Hydrolases
Capsules
4 引用 (Scopus)

Molecular mechanism of caspase-3-induced gene expression of polyplexes formed from polycations grafted with cationic substrate peptides

Kawamura, K., Kuramoto, M., Mori, T., Toita, R., Oishi, J., Sato, Y., Kang, J. H., Asai, D., Niidome, T. & Katayama, Y., 4 1 2009, : : Journal of Biomaterials Science, Polymer Edition. 20, 7-8, p. 967-980 14 p.

研究成果: ジャーナルへの寄稿記事

Gene expression
Caspase 3
Peptides
DNA
Transcription
15 引用 (Scopus)

Monitoring protein kinase activity in cell lysates using a high-density peptide microarray

Han, X., Yamanouchi, G., Mori, T., Kang, J. H., Niidome, T. & Katayama, Y., 3 1 2009, : : Journal of Biomolecular Screening. 14, 3, p. 256-262 7 p.

研究成果: ジャーナルへの寄稿記事

Microarrays
Protein Kinases
Phosphotransferases
Screening
Peptides
199 引用 (Scopus)

Nanoparticles of Adaptive Supramolecular Networks Self-Assembled from Nucleotides and Lanthanide Ions

Nishiyabu, R., Hashimoto, N., Cho, T., Watanabe, K., Yasunaga, T., Endo, A., Kaneko, K., Niidome, T., Murata, M., Adachi, C., Katayama, Y., Hashizume, M. & Kimizuka, N., 2 18 2009, : : Journal of the American Chemical Society. 131, 6, p. 2151-2158 8 p.

研究成果: ジャーナルへの寄稿記事

Lanthanoid Series Elements
Nucleotides
Rare earth elements
Nanoparticles
Ions
13 引用 (Scopus)

NFκB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice

Sugao, Y., Watanabe, K., Higuchi, Y., Kurihara, R., Kawakami, S., Hashida, M., Katayama, Y. & Niidome, T., 7 15 2009, : : Bioorganic and Medicinal Chemistry. 17, 14, p. 4990-4995 6 p.

研究成果: ジャーナルへの寄稿記事

Endotoxins
Liver
Hepatitis
Lysine
Oligonucleotides
1 引用 (Scopus)

Phosphatidylserine-selective conformational change of α-helix peptide, Td3717, and its ability to transfect cancer cells

Kuriyama, S., Nishimura, K., Taguchi, Y., Yanagibashi, K., Katayama, Y. & Niidome, T., 7 20 2009, : : Chemistry Letters. 38, 7, p. 684-685 2 p.

研究成果: ジャーナルへの寄稿記事

Phosphatidylserines
Cells
Phosphatidylglycerols
Peptides
Coulomb interactions
23 引用 (Scopus)

Photochemical reaction of poly(ethylene glycol) on gold nanorods induced by near infrared pulsed-laser irradiation

Yamashita, S., Niidome, Y., Katayama, Y. & Niidome, T., 2009, : : Chemistry Letters. 38, 3, p. 226-227 2 p.

研究成果: ジャーナルへの寄稿記事

Infrared lasers
Photochemical reactions
Laser beam effects
Nanorods
Pulsed lasers
25 引用 (Scopus)

Plasma protein kinase C (PKC)α as a biomarker for the diagnosis of cancers

Kang, J. H., Asai, D., Toita, R., Kitazaki, H. & Katayama, Y., 12 4 2009, : : Carcinogenesis. 30, 11, p. 1927-1931 5 p.

研究成果: ジャーナルへの寄稿記事

Tumor Biomarkers
Protein Kinase C
Blood Proteins
Neoplasms
Phosphorylation
184 引用 (Scopus)

PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser

Kawano, T., Niidome, Y., Mori, T., Katayama, Y. & Niidome, T., 2 1 2009, : : Bioconjugate Chemistry. 20, 2, p. 209-212 4 p.

研究成果: ジャーナルへの寄稿記事

Nanotubes
Infrared lasers
Nanorods
Gold
Lasers
73 引用 (Scopus)

Poly(ethylene glycol)-modified gold nanorods as a photothermal nanodevice for hyperthermia

Niidome, T., Akiyama, Y., Yamagata, M., Kawano, T., Mori, T., Niidome, Y. & Katayama, Y., 5 1 2009, : : Journal of Biomaterials Science, Polymer Edition. 20, 9, p. 1203-1215 13 p.

研究成果: ジャーナルへの寄稿記事

Nanotubes
Ethylene Glycol
Nanorods
Gold
Polyethylene glycols
17 引用 (Scopus)

Protein kinase Cα-responsive polymeric carrier: Its application for gene delivery into human cancers

Tomiyama, T., Kang, J. H., Toita, R., Niidome, T. & Katayama, Y., 7 23 2009, : : Cancer Science. 100, 8, p. 1532-1536 5 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Polymers
Serine
Genes
Neoplasms
19 引用 (Scopus)

Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems

Toita, R., Kang, J. H., Kim, J. H., Tomiyama, T., Mori, T., Niidome, T., Jun, B. & Katayama, Y., 10 15 2009, : : Journal of Controlled Release. 139, 2, p. 133-139 7 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Transplants
Peptides
Genes
Neoplasms
3 引用 (Scopus)

Regulation of transgene expression in tumor cells by exploiting endogenous intracellular signals

Asai, D., Kang, J. H., Toita, R., Tsuchiya, A., Niidome, T., Nakashima, H. & Katayama, Y., 3 1 2009, : : Nanoscale Research Letters. 4, 3, p. 229-233 5 p.

研究成果: ジャーナルへの寄稿記事

Tumors
DNA
tumors
deoxyribonucleic acid
Cells
2 引用 (Scopus)
Phosphorylation
Protein Kinase C
Phosphatidylserines
Estradiol
Estrogens
11 引用 (Scopus)

Signal-to-noise ratio improvement of peptide microarrays by using hyperbranched-polymer materials

Mori, T., Yamanouchi, G., Han, X., Inoue, Y., Shigaki, S., Yamaji, T., Sonoda, T., Yasui, K., Hayashi, H., Niidome, T. & Katayama, Y., 6 11 2009, : : Journal of Applied Physics. 105, 10, 102020.

研究成果: ジャーナルへの寄稿記事

dendrimers
peptides
signal to noise ratios
fabrication
glass
2 引用 (Scopus)

Stability of DNA/Td3717 complexes for gene transfection, defined by the size and polydispersity of the complex

Kuriyama, S., Taguchi, Y., Watanabe, K., Nishimura, K., Yanagibashi, K., Katayama, Y. & Niidome, T., 11 15 2009, : : Bioorganic and Medicinal Chemistry. 17, 22, p. 7643-7646 4 p.

研究成果: ジャーナルへの寄稿記事

Polydispersity
Transfection
Genes
DNA
Peptides
22 引用 (Scopus)

Syndiotactic poly(N-n-propylacrylamide) shows highly cooperative phase transition

Mori, T., Hirano, T., Maruyama, A., Katayama, Y., Niidome, T., Bando, Y., Ute, K., Takaku, S. & Maeda, Y., 1 6 2009, : : Langmuir. 25, 1, p. 48-50 3 p.

研究成果: ジャーナルへの寄稿記事

Phase transitions
Infrared spectroscopy
Polymers
polymers
spectroscopy
154 引用 (Scopus)

The effects of PEG grafting level and injection dose on gold nanorod biodistribution in the tumor-bearing mice

Akiyama, Y., Mori, T., Katayama, Y. & Niidome, T., 10 1 2009, : : Journal of Controlled Release. 139, 1, p. 81-84 4 p.

研究成果: ジャーナルへの寄稿記事

Nanotubes
Gold
Injections
Neoplasms
Mononuclear Phagocyte System
2008
25 引用 (Scopus)

A quantitative peptide array for evaluation of protein kinase activity

Han, X., Shigaki, S., Yamaji, T., Yamanouchi, G., Mori, T., Niidome, T. & Katayama, Y., 1 1 2008, : : Analytical Biochemistry. 372, 1, p. 106-115 10 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinases
Peptides
Preclinical Drug Evaluations
Phosphorylation
Optical Imaging
38 引用 (Scopus)

A short peptide is a protein kinase C (PKC) α-specific substrate

Kang, J. H., Asai, D., Yamada, S., Toita, R., Oishi, J., Mori, T., Niidome, T. & Katayama, Y., 5 1 2008, : : Proteomics. 8, 10, p. 2006-2011 6 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Peptides
Substrates
Isoenzymes
Phosphorylation

Bisphenol A in the aquatic environment and its endocrine-disruptive effects on aquatic organisms (Critical Reviews in Toxicology 37, 7)

Kang, J. H., Asai, D. & Katayama, Y., 2 1 2008, : : Critical Reviews in Toxicology. 38, 2, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Aquatic Organisms
Toxicology
bisphenol A
54 引用 (Scopus)

Colorimetric enzymatic activity assay based on noncrosslinking aggregation of gold nanoparticles induced by adsorption of substrate peptides

Oishi, J., Asami, Y., Mori, T., Kang, J. H., Niidome, T. & Katayama, Y., 9 1 2008, : : Biomacromolecules. 9, 9, p. 2301-2308 8 p.

研究成果: ジャーナルへの寄稿記事

Gold
Peptides
Assays
Agglomeration
Nanoparticles
57 引用 (Scopus)

Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells

Kang, J. H., Asai, D., Kim, J. H., Mori, T., Toita, R., Tomiyama, T., Asami, Y., Oishi, J., Sato, Y. T., Niidome, T., Jun, B., Nakashima, H. & Katayama, Y., 11 12 2008, : : Journal of the American Chemical Society. 130, 45, p. 14906-14907 2 p.

研究成果: ジャーナルへの寄稿記事

Gene Targeting
Neoplasm Genes
Protein Kinase C
Genes
Chemical activation
10 引用 (Scopus)

Development of polymeric drug delivery system for recognizing vascular endothelial dysfunction

Ikuta, K., Mori, T., Yamamoto, T., Niidome, T., Shimokawa, H. & Katayama, Y., 3 15 2008, : : Bioorganic and Medicinal Chemistry. 16, 6, p. 2811-2818 8 p.

研究成果: ジャーナルへの寄稿記事

Drug Delivery Systems
Doxorubicin
Endothelium
Blood Vessels
Drug Carriers
6 引用 (Scopus)

Drug delivery system based on responses to an HIV infectious signal

Asai, D., Kodama, K. B., Shoji, Y., Nakashima, H., Kawamura, K., Oishi, J., Kuramoto, M., Niidome, T. & Katayama, Y., 8 28 2008, : : Medicinal chemistry. 4, 4, p. 386-391 6 p.

研究成果: ジャーナルへの寄稿記事

HIV Protease
Drug Delivery Systems
HIV
Polymers
Genetic Therapy
9 引用 (Scopus)

Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex

Kang, J. H., Toita, R., Niidome, T. & Katayama, Y., 7 8 2008, : : Cancer Letters. 265, 2, p. 281-288 8 p.

研究成果: ジャーナルへの寄稿記事

Electroporation
Polymers
DNA
Neoplasms
Experimental Melanomas
89 引用 (Scopus)

Efficient delivery of siRNA using dendritic poly(l-lysine) for loss-of-function analysis

Inoue, Y., Kurihara, R., Tsuchida, A., Hasegawa, M., Nagashima, T., Mori, T., Niidome, T., Katayama, Y. & Okitsu, O., 2 18 2008, : : Journal of Controlled Release. 126, 1, p. 59-66 8 p.

研究成果: ジャーナルへの寄稿記事

Metformin
Small Interfering RNA
Lysine
Gluconeogenesis
Organic Cation Transporter 1
48 引用 (Scopus)

Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging

Mori, T., Inamori, K., Inoue, Y., Han, X., Yamanouchi, G., Niidome, T. & Katayama, Y., 4 15 2008, : : Analytical Biochemistry. 375, 2, p. 223-231 9 p.

研究成果: ジャーナルへの寄稿記事

Surface Plasmon Resonance
Surface plasmon resonance
Microarrays
Protein Kinases
Cells
26 引用 (Scopus)

High-throughput colorimetric detection of tyrosine kinase inhibitors based on the aggregation of gold nanoparticles

Oishi, J., Han, X., Kang, J. H., Asami, Y., Mori, T., Niidome, T. & Katayama, Y., 2 1 2008, : : Analytical Biochemistry. 373, 1, p. 161-163 3 p.

研究成果: ジャーナルへの寄稿記事

Proto-Oncogene Proteins
Metal Nanoparticles
Colorimetry
Phosphorylation
Metal nanoparticles
7 引用 (Scopus)

In vivo magnetic resonance imaging of atherosclerotic lesions with a newly developed evans blue-DTPA-gadolinium contrast medium in apolipoprotein-E- deficient mice

Yasuda, S., Ikuta, K., Uwatoku, T., Oi, K., Abe, K., Hyodo, F., Yoshimitsu, K., Sugimura, K., Utsumi, H., Katayama, Y. & Shimokawa, H., 2 1 2008, : : Journal of Vascular Research. 45, 2, p. 123-128 6 p.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins E
Contrast Media
Atherosclerotic Plaques
Magnetic Resonance Imaging
Intravenous Injections
48 引用 (Scopus)

In vivo monitoring of intravenously injected gold nanorods using near-infrared light

Niidome, T., Akiyama, Y., Shimoda, K., Kawano, T., Mori, T., Katayama, Y. & Niidome, Y., 7 1 2008, : : Small. 4, 7, p. 1001-1007 7 p.

研究成果: ジャーナルへの寄稿記事

Nanotubes
Nanorods
Gold
Infrared radiation
Light
5 引用 (Scopus)

Letter: Correlation between phosphorylation ratios by matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis and enzyme kinetics

Kang, J. H., Kuramoto, M., Tsuchiya, A., Toita, R., Asai, D., Sato, Y. T., Mori, T., Niidome, T. & Katayama, Y., 10 15 2008, : : European Journal of Mass Spectrometry. 14, 4, p. 261-265 5 p.

研究成果: ジャーナルへの寄稿記事

Enzyme kinetics
phosphorylation
Phosphorylation
Ionization
Mass spectrometry
40 引用 (Scopus)

Optimal surface chemistry for peptide immobilization in on-chip phosphorylation analysis

Inamori, K., Kyo, M., Matsukawa, K., Inoue, Y., Sonoda, T., Tatematsu, K., Tanizawa, K., Mori, T. & Katayama, Y., 2 1 2008, : : Analytical chemistry. 80, 3, p. 643-650 8 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Surface chemistry
Peptides
Polyethylene glycols
Cyclic AMP-Dependent Protein Kinases