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研究成果

コメント/討論

The secrets of the bone marrow niche: Enigmatic niche brings challenge for HSC expansion

Kunisaki, Y. & Frenette, P. S., 6 1 2012, : : Nature medicine. 18, 6, p. 864-865 2 p.

研究成果: ジャーナルへの寄稿コメント/討論

24 引用 (Scopus)
レター

Marked improvement of cardiac function early after non-myeloablative BMT in a heavily transfused patient with severe aplastic anemia and heart failure [1]

Kunisaki, Y., Takase, K., Miyamoto, T., Fukata, M., Nonami, A., Kamezaki, K., Kaji, Y., Gondo, H., Harada, M. & Nagafuji, K., 9 1 2007, : : Bone Marrow Transplantation. 40, 6, p. 593-595 3 p.

研究成果: ジャーナルへの寄稿レター

2 引用 (Scopus)
記事

Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell Niche

Hanoun, M., Zhang, D., Mizoguchi, T., Pinho, S., Pierce, H., Kunisaki, Y., Lacombe, J., Armstrong, S. A., Dührsen, U. & Frenette, P. S., 1 1 2014, : : Cell stem cell. 15, 3, p. 365-375 11 p.

研究成果: ジャーナルへの寄稿記事

149 引用 (Scopus)

Adrenergic nerves govern circadian leukocyte recruitment to tissues

Scheiermann, C., Kunisaki, Y., Lucas, D., Chow, A., Jang, J. E., Zhang, D., Hashimoto, D., Merad, M. & Frenette, P. S., 8 24 2012, : : Immunity. 37, 2, p. 290-301 12 p.

研究成果: ジャーナルへの寄稿記事

207 引用 (Scopus)

Arteriolar niches maintain haematopoietic stem cell quiescence

Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., Mar, J. C., Bergman, A. & Frenette, P. S., 10 10 2013, : : Nature. 502, 7473, p. 637-643 7 p.

研究成果: ジャーナルへの寄稿記事

542 引用 (Scopus)

CD169 + macrophages provide a niche promoting erythropoiesis under homeostasis and stress

Chow, A., Huggins, M., Ahmed, J., Hashimoto, D., Lucas, D., Kunisaki, Y., Pinho, S., Leboeuf, M., Noizat, C., Van Rooijen, N., Tanaka, M., Zhao, Z. J., Bergman, A., Merad, M. & Frenette, P. S., 4 1 2013, : : Nature medicine. 19, 4, p. 429-436 8 p.

研究成果: ジャーナルへの寄稿記事

203 引用 (Scopus)

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

Oshima, T., Niwa, Y., Kuwata, K., Srivastava, A., Hyoda, T., Tsuchiya, Y., Kumagai, M., Tsuyuguchi, M., Tamaru, T., Sugiyama, A., Ono, N., Zolboot, N., Aikawa, Y., Oishi, S., Nonami, A., Arai, F., Hagihara, S., Yamaguchi, J., Tama, F., Kunisaki, Y. および6人, Yagita, K., Ikeda, M., Kinoshita, T., Kay, S. A., Itami, K. & Hirota, T., 1 23 2019, : : Science Advances. 5, 1, eaau9060.

研究成果: ジャーナルへの寄稿記事

公開
10 引用 (Scopus)

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

Lucas, D., Scheiermann, C., Chow, A., Kunisaki, Y., Bruns, I., Barrick, C., Tessarollo, L. & Frenette, P. S., 6 1 2013, : : Nature medicine. 19, 6, p. 695-703 9 p.

研究成果: ジャーナルへの寄稿記事

117 引用 (Scopus)

Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer

Nakano, M., Kikushige, Y., Miyawaki, K., Kunisaki, Y., Mizuno, S., Takenaka, K., Tamura, S., Okumura, Y., Ito, M., Ariyama, H., Kusaba, H., Nakamura, M., Maeda, T., Baba, E. & Akashi, K., 2 7 2019, : : Oncogene. 38, 6, p. 780-793 14 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor

Kunisaki, Y., Masuko, S., Noda, M., Inayoshi, A., Sanui, T., Harada, M., Sasazuki, T. & Fukui, Y., 5 1 2004, : : Blood. 103, 9, p. 3362-3364 3 p.

研究成果: ジャーナルへの寄稿記事

87 引用 (Scopus)

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

Jiang, H., Pan, F., Erickson, L. M., Jang, M. S., Sanui, T., Kunisaki, Y., Sasazuki, T., Kobayashi, M. & Fukui, Y., 10 17 2005, : : Journal of Experimental Medicine. 202, 8, p. 1121-1130 10 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)
4 引用 (Scopus)

Differential cytokine contributions of perivascular haematopoietic stem cell niches

Asada, N., Kunisaki, Y., Pierce, H., Wang, Z., Fernandez, N. F., Birbrair, A., Ma'ayan, A. & Frenette, P. S., 3 1 2017, : : Nature Cell Biology. 19, 3, p. 214-223 10 p.

研究成果: ジャーナルへの寄稿記事

115 引用 (Scopus)

Differential requirements for DOCK2 and phosphoinositide-3-kinase γ during T and B lymphocyte homing

Nombela-Arrieta, C., Lacalle, R. A., Montoya, M. C., Kunisaki, Y., Megías, D., Marqués, M., Carrera, A. C., Mañes, S., Fukui, Y., Martínez-A, C. & Stein, J. V., 9 1 2004, : : Immunity. 21, 3, p. 429-441 13 p.

研究成果: ジャーナルへの寄稿記事

186 引用 (Scopus)

Distinct vascular niches determine hematopoietic stem cell fate

Kunisaki, Y., 6 1 2015, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 56, 6, p. 606-613 8 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Kunisaki, Y., Nishikimi, A., Tanaka, Y., Takii, R., Noda, M., Inayoshi, A., Watanabe, K. I., Sanematsu, F., Sasazuki, T., Sasaki, T. & Fukui, Y., 8 28 2006, : : Journal of Cell Biology. 174, 5, p. 647-652 6 p.

研究成果: ジャーナルへの寄稿記事

143 引用 (Scopus)

DOCK2 is required in T cell precursors for development of Vα14 NK T cells

Kunisaki, Y., Tanaka, Y., Sanui, T., Inayoshi, A., Noda, M., Nakayama, T., Harada, M., Taniguchi, M., Sasazuki, T. & Fukui, Y., 4 15 2006, : : Journal of Immunology. 176, 8, p. 4640-4645 6 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with KitWv Mutations

Yurino, A., Takenaka, K., Yamauchi, T., Nunomura, T., Uehara, Y., Jinnouchi, F., Miyawaki, K., Kikushige, Y., Kato, K., Miyamoto, T., Iwasaki, H., Kunisaki, Y. & Akashi, K., 9 13 2016, : : Stem Cell Reports. 7, 3, p. 425-438 14 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Fetal liver hematopoietic stem cell niches associate with portal vessels

Khan, J. A., Mendelson, A., Kunisaki, Y., Birbrair, A., Kou, Y., Arnal-Estapé, A., Pinho, S., Ciero, P., Nakahara, F., Ma'ayan, A., Bergman, A., Merad, M. & Frenette, P. S., 1 1 2016, : : Science. 351, 6269, p. 176-180 5 p.

研究成果: ジャーナルへの寄稿記事

91 引用 (Scopus)
2 引用 (Scopus)

Hypercholesterolemia as a part of chronic GVHD after allogeneic stem cell transplantation

Koyama, M., Matsuoka, K. I., Kunisaki, Y., Takeuchi, M. & Matsue, K., 1 1 2004, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 45, 10, p. 1115-1118 4 p.

研究成果: ジャーナルへの寄稿記事

Identification of unipotent megakaryocyte progenitors in human hematopoiesis

Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., 6 22 2017, : : Blood. 129, 25, p. 3332-3343 12 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Influences of vascular niches on hematopoietic stem cell fate

Kunisaki, Y. & Frenette, P. S., 6 2014, : : International journal of hematology. 99, 6, p. 699-705 7 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

Bruns, I., Lucas, D., Pinho, S., Ahmed, J., Lambert, M. P., Kunisaki, Y., Scheiermann, C., Schiff, L., Poncz, M., Bergman, A. & Frenette, P. S., 11 1 2014, : : Nature medicine. 20, 11, p. 1315-1320 6 p.

研究成果: ジャーナルへの寄稿記事

238 引用 (Scopus)

Neutrophil ageing is regulated by the microbiome

Zhang, D., Chen, G., Manwani, D., Mortha, A., Xu, C., Faith, J. J., Burk, R. D., Kunisaki, Y., Jang, J. E., Scheiermann, C., Merad, M. & Frenette, P. S., 9 24 2015, : : Nature. 525, 7570, p. 528-532 5 p.

研究成果: ジャーナルへの寄稿記事

226 引用 (Scopus)

Norepinephrine reuptake inhibition promotes mobilization in mice: Potential impact to rescue low stem cell yields

Lucas, D., Bruns, I., Battista, M., Mendez-Ferrer, S., Magnon, C., Kunisaki, Y. & Frenette, P. S., 4 19 2012, : : Blood. 119, 17, p. 3962-3965 4 p.

研究成果: ジャーナルへの寄稿記事

57 引用 (Scopus)

Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development

Mizoguchi, T., Pinho, S., Ahmed, J., Kunisaki, Y., Hanoun, M., Mendelson, A., Ono, N., Kronenberg, H. M. & Frenette, P. S., 5 12 2014, : : Developmental Cell. 29, 3, p. 340-349 10 p.

研究成果: ジャーナルへの寄稿記事

162 引用 (Scopus)

PDGFRα and CD51 mark human Nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion

Pinho, S., Lacombe, J., Hanoun, M., Mizoguchi, T., Bruns, I., Kunisaki, Y. & Frenette, P. S., 7 1 2013, : : Journal of Experimental Medicine. 210, 7, p. 1351-1367 17 p.

研究成果: ジャーナルへの寄稿記事

226 引用 (Scopus)

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

Hashimoto, D., Chow, A., Greter, M., Saenger, Y., Kwan, W. H., Leboeuf, M., Ginhoux, F., Ochando, J. C., Kunisaki, Y., van Rooijen, N., Liu, C., Teshima, T., Heeger, P. S., Stanley, E. R., Frenette, P. S. & Merad, M., 5 1 2011, : : Journal of Experimental Medicine. 208, 5, p. 1069-1082 14 p.

研究成果: ジャーナルへの寄稿記事

87 引用 (Scopus)

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

Kidoya, H., Muramatsu, F., Shimamura, T., Jia, W., Satoh, T., Hayashi, Y., Naito, H., Kunisaki, Y., Arai, F., Seki, M., Suzuki, Y., Osawa, T., Akira, S. & Takakura, N., 12 1 2019, : : Nature communications. 10, 1, 1072.

研究成果: ジャーナルへの寄稿記事

公開
2 引用 (Scopus)

Salazosulfapyridine induced hypersensitivity syndrome associated with reactivation of humanherpes virus 6

Kunisaki, Y., Goto, H., Kitagawa, K. & Nagano, M., 2 1 2003, : : Internal Medicine. 42, 2, p. 203-207 5 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Successful treatment of primary plasma cell leukaemia by allogeneic stem cell transplantation from haploidentical sibling

Nonami, A., Miyamoto, T., Kuroiwa, M., Kunisaki, Y., Kamezaki, K., Takenaka, K., Harada, N., Teshima, T., Harada, M. & Nagafuji, K., 12 1 2007, : : Japanese journal of clinical oncology. 37, 12, p. 969-972 4 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

The hematopoietic stem cell niche

Kunisaki, Y., 10 1 2015, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 56, 10, p. 1888-1893 6 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2

Tanaka, Y., Hamano, S., Gotoh, K., Murata, Y., Kunisaki, Y., Nishikimi, A., Takii, R., Kawaguchi, M., Inayoshi, A., Masuko, S., Himeno, K., Sasazuki, T. & Fukui, Y., 10 1 2007, : : Nature Immunology. 8, 10, p. 1067-1075 9 p.

研究成果: ジャーナルへの寄稿記事

48 引用 (Scopus)

Toxoplasmosis encephalitis following severe graft-vs.-host disease after allogeneic hematopoietic stem cell transplantation: 17 Yr experience in Fukuoka BMT group

Matsuo, Y., Takeishi, S., Miyamoto, T., Nonami, A., Kikushige, Y., Kunisaki, Y., Kamezaki, K., Tu, L., Hisaeda, H., Takenaka, K., Harada, N., Kamimura, T., Ohno, Y., Eto, T., Teshima, T., Gondo, H., Harada, M. & Nagafuji, K., 10 1 2007, : : European Journal of Haematology. 79, 4, p. 317-321 5 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

XRhythmic modulation of the hematopoietic niche through neutrophil clearance

Casanova-Acebes, M., Pitaval, C., Weiss, L. A., Nombela-Arrieta, C., Chèvre, R., A-González, N., Kunisaki, Y., Zhang, D., Van Rooijen, N., Silberstein, L. E., Weber, C., Nagasawa, T., Frenette, P. S., Castrillo, A. & Hidalgo, A., 5 23 2013, : : Cell. 153, 5, 1 p.

研究成果: ジャーナルへの寄稿記事

242 引用 (Scopus)

Pericytes in bone marrow

Kunisaki, Y., 1 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 101-114 14 p. (Advances in Experimental Medicine and Biology; 巻数 1122).

研究成果: 著書/レポートタイプへの貢献

1 引用 (Scopus)
評論記事

Cancer stem cells and the niches

Kunisaki, Y., 5 1 2015, : : Nihon rinsho. Japanese journal of clinical medicine. 73, 5, p. 739-744 6 p.

研究成果: ジャーナルへの寄稿評論記事

1 引用 (Scopus)

Circadian control of the immune system

Scheiermann, C., Kunisaki, Y. & Frenette, P. S., 3 1 2013, : : Nature Reviews Immunology. 13, 3, p. 190-198 9 p.

研究成果: ジャーナルへの寄稿評論記事

354 引用 (Scopus)

Neutrophil microdomains: Linking heterocellular interactions with vascular injury

Scheiermann, C., Kunisaki, Y., Jang, J. E. & Frenette, P. S., 1 1 2010, : : Current Opinion in Hematology. 17, 1, p. 25-30 6 p.

研究成果: ジャーナルへの寄稿評論記事

12 引用 (Scopus)