抄録
Alkyl N,N-diisopropylcarbamates, when lithiated with s-BuLi/(-)-sparteine in ether at -78 °C followed by warming to room temperature, are shown to undergo the 1,2-carbamoyl migration to give the α-hydroxy amides in >95% ee with complete retention of configuration at the Li-bearing carbanion terminus. An addition-elimination mechanism is proposed.
本文言語 | 英語 |
---|---|
ページ(範囲) | 759-760 |
ページ数 | 2 |
ジャーナル | Chemistry Letters |
号 | 8 |
DOI | |
出版ステータス | 出版済み - 1999 |
外部発表 | はい |
!!!All Science Journal Classification (ASJC) codes
- 化学 (全般)