2-Amino-6-vinyl purine as a tool for post synthetic conjugation of DNA with radio-, spin-, fluorescence labels and peptides.

Md Monsur Ali, Fumi Nagatsugi, Fumihiko Yamamoto, Minoru Maeda, Shigeki Sasaki

研究成果: Contribution to journalArticle査読

抄録

We have previously demonstrated that 2-amino-6-vinylpurine is an efficient cross-linking agent with high selectivity towards cytidine. In this study, we applied this nucleobase analog to versatile conjugation of oligodeoxynucleotides with radio-, spin-, fluorescence- and peptide labels. The oligodeoxynucleotides incorporating 2-amino-6-vinylpurine nucleoside were reacted with amino- bearing nucleophies in an excess amount to give the corresponding conjugates in good yield.

本文言語英語
ページ(範囲)149-150
ページ数2
ジャーナルNucleic acids research. Supplement (2001)
2
出版ステータス出版済み - 2002

All Science Journal Classification (ASJC) codes

  • Medicine(all)

フィンガープリント 「2-Amino-6-vinyl purine as a tool for post synthetic conjugation of DNA with radio-, spin-, fluorescence labels and peptides.」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル