6-Vinylated guanosine as a novel cross-linking agent and its versatile synthesis from the 6-O-tosylate by Pd(0)-catalyzed cross-coupling

Fumi Nagatsugi, Kengo Uemura, Shouji Nakashima, Minoru Maeda, Shigeki Sasaki

研究成果: Contribution to journalArticle査読

78 被引用数 (Scopus)

抄録

6-Vinylated guanosine (1) was designed as a novel cross-linking agent, and synthesized by a new Pd(0)-catalyzed cross-coupling reaction using guanosine 6-O-tosylate and vinyltributylstannane. Its potential as a cross-linking agent was demonstrated by adduct formation with guanosine and cytidine at the 7-N and 4-N positions, respectively.

本文言語英語
ページ(範囲)421-424
ページ数4
ジャーナルTetrahedron Letters
36
3
DOI
出版ステータス出版済み - 1 16 1995

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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