6-Vinylated guanosine as a novel cross-linking agent and its versatile synthesis from the 6-O-tosylate by Pd(0)-catalyzed cross-coupling

Fumi Nagatsugi; Kengo Uemura; Shouji Nakashima; Minoru Maeda; Shigeki Sasaki

doi:10.1016/0040-4039(94)02224-Y

6-Vinylated guanosine as a novel cross-linking agent and its versatile synthesis from the 6-O-tosylate by Pd(0)-catalyzed cross-coupling

Fumi Nagatsugi, Kengo Uemura, Shouji Nakashima, Minoru Maeda, Shigeki Sasaki

医薬化学

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

78 被引用数 (Scopus)

抄録

6-Vinylated guanosine (1) was designed as a novel cross-linking agent, and synthesized by a new Pd(0)-catalyzed cross-coupling reaction using guanosine 6-O-tosylate and vinyltributylstannane. Its potential as a cross-linking agent was demonstrated by adduct formation with guanosine and cytidine at the 7-N and 4-N positions, respectively.

本文言語	英語
ページ（範囲）	421-424
ページ数	4
ジャーナル	Tetrahedron Letters
巻	36
号	3
DOI	https://doi.org/10.1016/0040-4039(94)02224-Y
出版ステータス	出版済み - 1月 16 1995

!!!All Science Journal Classification (ASJC) codes

生化学
創薬
有機化学

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10.1016/0040-4039(94)02224-Y

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引用スタイル

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AU - Sasaki, Shigeki

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