研究成果の検索

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選択されたフィルター
2016
14 引用 (Scopus)

Anti-inflammatory nanoparticle for prevention of atherosclerotic vascular diseases

Koga, J. I., Matoba, T. & Egashira, K., 1 1 2016, : : Journal of atherosclerosis and thrombosis. 23, 7, p. 757-765 9 p.

研究成果: ジャーナルへの寄稿記事

Vascular Diseases
Nanoparticles
Anti-Inflammatory Agents
Drug Delivery Systems
Tissue
9 引用 (Scopus)
myocardial infarction
nanoparticles
ischemia
myocardium
Reperfusion Injury
6 引用 (Scopus)

BubR1 Insufficiency Results in Decreased Macrophage Proliferation and Attenuated Atherogenesis in Apolipoprotein E-Deficient Mice

Tanaka, S., Matsumoto, T., Matsubara, Y., Harada, Y., Kyuragi, R., Koga, J. I., Egashira, K., Nakashima, Y., Yonemitsu, Y. & Maehara, Y., 9 2016, : : Journal of the American Heart Association. 5, 9, e004081.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins E
Atherosclerosis
Macrophages
Bone Marrow Cells
Bone Marrow
5 引用 (Scopus)

Critical role of the C5a-activated neutrophils in high-fat diet-induced vascular inflammation

Osaka, M., Ito, S., Honda, M., Inomata, Y., Egashira, K. & Yoshida, M., 2 19 2016, : : Scientific reports. 6, 21391.

研究成果: ジャーナルへの寄稿記事

High Fat Diet
Blood Vessels
Neutrophils
Inflammation
Leukocytes
102 引用 (Scopus)

Drp1-dependent mitochondrial autophagy plays a protective role against pressure overload-induced mitochondrial dysfunction and heart failure

Shirakabe, A., Zhai, P., Ikeda, Y., Saito, T., Maejima, Y., Hsu, C. P., Nomura, M., Egashira, K., Levine, B. & Sadoshima, J., 3 29 2016, : : Circulation. 133, 13, p. 1249-1263 15 p.

研究成果: ジャーナルへの寄稿記事

Autophagy
Heart Failure
Pressure
Constriction
Down-Regulation
3 引用 (Scopus)

Ezetimibe reduced hepatic steatosis induced by dietary oxysterols in nonhuman primates

Deushi, M., Osaka, M., Nakano, K., Osada, K., Egashira, K. & Yoshida, M., 10 1 2016, : : FEBS Open Bio. 6, 10, p. 1008-1015 8 p.

研究成果: ジャーナルへの寄稿記事

Primates
Cholesterol
Liver
Lipids
High Fat Diet
10 引用 (Scopus)

Intratracheal administration of prostacyclin analogue-incorporated nanoparticles ameliorates the development of monocrotaline and sugen-hypoxia-induced pulmonary arterial hypertension

Akagi, S., Nakamura, K., Matsubara, H., Kondo, M., Miura, D., Matoba, T., Egashira, K. & Ito, H., 4 2016, : : Journal of Cardiovascular Pharmacology. 67, 4, p. 290-298 9 p.

研究成果: ジャーナルへの寄稿記事

beraprost
Monocrotaline
Epoprostenol
Pulmonary Hypertension
Nanoparticles
20 引用 (Scopus)

Local delivery of mutant CCL2 protein-reduced orthopaedic implant wear particle-induced osteolysis and inflammation in vivo

Jiang, X., Sato, T., Yao, Z., Keeney, M., Pajarinen, J., Lin, T. H., Loi, F., Egashira, K., Goodman, S. & Yang, F., 1 1 2016, : : Journal of Orthopaedic Research. 34, 1, p. 58-64 7 p.

研究成果: ジャーナルへの寄稿記事

Osteolysis
Mutant Proteins
Orthopedics
Replacement Arthroplasties
Inflammation
29 引用 (Scopus)

Nanoparticle-mediated delivery of irbesartan induces cardioprotection from myocardial ischemia-reperfusion injury by antagonizing monocyte-mediated inflammation

Nakano, Y., Matoba, T., Tokutome, M., Funamoto, D., Katsuki, S., Ikeda, G., Nagaoka, K., Ishikita, A., Nakano, K., Koga, J. I., Sunagawa, K. & Egashira, K., 7 11 2016, : : Scientific reports. 6, 29601.

研究成果: ジャーナルへの寄稿記事

irbesartan
Myocardial Reperfusion Injury
Reperfusion Injury
Nanoparticles
Reperfusion
26 引用 (Scopus)
Reperfusion Injury
Nanoparticles
Myocardium
Mitochondria
Myocardial Infarction
28 引用 (Scopus)

Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening

Ikeda, G., Matoba, T., Nakano, Y., Nagaoka, K., Ishikita, A., Nakano, K., Funamoto, D., Sunagawa, K. & Egashira, K., 2 10 2016, : : Scientific reports. 6, 20467.

研究成果: ジャーナルへの寄稿記事

Reperfusion Injury
Nanoparticles
Cyclosporine
glycolic acid
Reperfusion
公開
Myocardium
Mitochondria
Myocardial Infarction
Membranes
Wounds and Injuries
38 引用 (Scopus)

Pioglitazone-incorporated nanoparticles prevent plaque destabilization and rupture by regulating monocyte/macrophage differentiation in ApoE -/-Mice

Nakashiro, S., Matoba, T., Umezu, R., Koga, J. I., Tokutome, M., Katsuki, S., Nakano, K., Sunagawa, K. & Egashira, K., 3 1 2016, : : Arteriosclerosis, thrombosis, and vascular biology. 36, 3, p. 491-500 10 p.

研究成果: ジャーナルへの寄稿記事

pioglitazone
Apolipoproteins E
Nanoparticles
Rupture
Monocytes
1 引用 (Scopus)

Response by Shirakabe et al to letter regarding article, "Drp1-dependent mitochondrial autophagy plays a protective role against pressure overload-induced mitochondrial dysfunction and heart failure"

Shirakabe, A., Zhai, P., Ikeda, Y., Saito, T., Maejima, Y., Hsu, C. P., Nomura, M., Egashira, K., Levine, B. & Sadoshima, J., 8 9 2016, : : Circulation. 134, 6, p. e75-e76

研究成果: ジャーナルへの寄稿レター

Autophagy
Mitochondria
Heart Failure
Pressure
17 引用 (Scopus)

The effect of local IL-4 delivery or CCL2 blockade on implant fixation and bone structural properties in a mouse model of wear particle induced osteolysis

Sato, T., Pajarinen, J., Behn, A., Jiang, X., Lin, T. H., Loi, F., Yao, Z., Egashira, K., Yang, F. & Goodman, S. B., 9 1 2016, : : Journal of Biomedical Materials Research - Part A. 104, 9, p. 2255-2262 8 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-4
Structural properties
Bone
Wear of materials
Macrophages
2017

Anti-inflammatory Nanomedicine for Cardiovascular Disease

Katsuki, S., Matoba, T., Koga, J-I., Nakano, K. & Egashira, K., 2017, : : Frontiers in cardiovascular medicine. 4, p. 87

研究成果: ジャーナルへの寄稿評論記事

Nanomedicine
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Nanotechnology
Anti-Inflammatory Agents
Cardiovascular Diseases
11 引用 (Scopus)

Ezetimibe in combination with statins ameliorates endothelial dysfunction in coronary arteries after stenting: the CuVIC trial (effect of cholesterol absorption inhibitor usage on target vessel dysfunction after coronary stenting), a multicenter randomized controlled trial

Takase, S., Matoba, T., Nakashiro, S., Mukai, Y., Inoue, S., Oi, K., Higo, T., Katsuki, S., Takemoto, M., Suematsu, N., Eshima, K., Miyata, K., Yamamoto, M., Usui, M., Sadamatsu, K., Satoh, S., Kadokami, T., Hironaga, K., Ichi, I., Todaka, K. および3人, Kishimoto, J., Egashira, K. & Sunagawa, K., 2 2017, : : Arteriosclerosis, thrombosis, and vascular biology. 37, 2, p. 350-358 9 p.

研究成果: ジャーナルへの寄稿記事

Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coronary Vessels
Randomized Controlled Trials
Coronary Angiography
5 引用 (Scopus)

Marked augmentation of plga nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice

Kozuka, C., Shimizu-Okabe, C., Takayama, C., Nakano, K., Morinaga, H., Kinjo, A., Fukuda, K., Kamei, A., Yasuoka, A., Kondo, T., Abe, K., Egashira, K. & Masuzaki, H., 2 9 2017, : : Drug Delivery. 24, 1, p. 558-568 11 p.

研究成果: ジャーナルへの寄稿記事

Nanoparticles
Endoplasmic Reticulum Stress
Islets of Langerhans
Hypothalamus
Polyglactin 910
14 引用 (Scopus)

Mutant CCL2 protein coating mitigates wear particle-induced bone loss in a murine continuous polyethylene infusion model

Nabeshima, A., Pajarinen, J., Lin, T. H., Jiang, X., Gibon, E., Córdova, L. A., Loi, F., Lu, L., Jämsen, E., Egashira, K., Yang, F., Yao, Z. & Goodman, S. B., 2 1 2017, : : Biomaterials. 117, p. 1-9 9 p.

研究成果: ジャーナルへの寄稿記事

Polyethylene
Mutant Proteins
Macrophages
Polyethylenes
Bone
17 引用 (Scopus)
Ventricular Remodeling
Nanoparticles
Monocytes
Macrophages
Myocardial Infarction
16 引用 (Scopus)

Nanoparticle-mediated drug delivery system for atherosclerotic cardiovascular disease

Matoba, T., Koga, J. I., Nakano, K., Egashira, K. & Tsutsui, H., 9 1 2017, : : Journal of Cardiology. 70, 3, p. 206-211 6 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Delivery Systems
Nanoparticles
Cardiovascular Diseases
pioglitazone
Monocytes

Nanoparticle-mediated endothelial cell-selective drug delivery system

Nakano, K., Koga, J. I. & Egashira, K., 7 11 2017, Therapeutic Angiogenesis. Springer Singapore, p. 247-266 20 p.

研究成果: 著書/レポートタイプへの貢献

Endothelial cells
Nanotechnology
Nanoparticles
Restoration
Skin
2018
1 引用 (Scopus)

BubR1 insufficiency impairs angiogenesis in aging and in experimental critical limb ischemic mice

Okadome, J., Matsumoto, T., Yoshiya, K., Matsuda, D., Tamada, K., Onimaru, M., Nakano, K., Egashira, K., Yonemitsu, Y. & Maehara, Y., 8 2018, : : Journal of Vascular Surgery. 68, 2, p. 576-586.e1

研究成果: ジャーナルへの寄稿記事

Extremities
Ambulatory Surgical Procedures
Muscles
Ischemia
Vascular Endothelial Growth Factor A
3 引用 (Scopus)

Lipid-Lowering Therapy with Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion

Honda, K., Matoba, T., Antoku, Y., Koga, J. I., Ichi, I., Nakano, K., Tsutsui, H. & Egashira, K., 4 1 2018, : : Arteriosclerosis, thrombosis, and vascular biology. 38, 4, p. 757-771 15 p.

研究成果: ジャーナルへの寄稿記事

Rabbits
Lipids
Thromboplastin
Serum
Arteries
2 引用 (Scopus)
Monocrotaline
Pulmonary Hypertension
Intravenous Administration
Nanoparticles
Pulmonary Artery
3 引用 (Scopus)
Intravenous Administration
Nanoparticles
Pharmacokinetics
Placebos
Research Personnel
2019
2 引用 (Scopus)

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J. I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., 6 1 2019, : : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

研究成果: ジャーナルへの寄稿記事

公開
Myocardial Reperfusion Injury
Toll-Like Receptor 4
Reperfusion Injury
Nanoparticles
Myocardial Ischemia

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J-I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., 6 1 2019, : : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

研究成果: ジャーナルへの寄稿記事

Myocardial Reperfusion Injury
Toll-Like Receptor 4
Reperfusion Injury
Nanoparticles
Myocardial Ischemia
6 引用 (Scopus)

Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models

Tokutome, M., Matoba, T., Nakano, Y., Okahara, A., Fujiwara, M., Koga, J. I., Nakano, K., Tsutsui, H. & Egashira, K., 2 1 2019, : : Cardiovascular research. 115, 2, p. 419-431 13 p.

研究成果: ジャーナルへの寄稿記事

pioglitazone
Nanomedicine
PPAR gamma
Monocytes
Animal Models