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出版年

  • 2019
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  • 2014
  • 2011

著者

  • Koichi Akashi
2014

The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell

Shima, T., Miyamoto, T., Kikushige, Y., Yuda, J., Tochigi, T., Yoshimoto, G., Kato, K., Takenaka, K., Iwasaki, H., Mizuno, S., Goto, N. & Akashi, K., 11 1 2014, : : Experimental Hematology. 42, 11, p. 955-965.e5

研究成果: Contribution to journalArticle

13 引用 (Scopus)
2015

Successful treatment of lupus cerebrovascular disease with mycophenolate mofetil

Higashioka, K., Yoshida, K., Oryoji, K., Kamada, K., Mizuki, S., Tsukamoto, H., Yokota, E. & Akashi, K., 9 1 2015, : : Internal Medicine. 54, 17, p. 2255-2259 5 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)
2011

Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer

Baba, E., Esaki, T., Ariyama, H., Mitsugi, K., Morikita, T., Fujishima, H., Kusaba, H., Nakano, S. & Akashi, K., 9 2011, : : Cancer chemotherapy and pharmacology. 68, 3, p. 611-617 7 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)
2018

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy

Kumagai, H., Kusaba, H., Yamanaka, T., Nio, K., Inadomi, K., Takayoshi, K., Ito, M., Tamura, S., Makiyama, A., Makiyama, C., Hirano, G., Shibata, Y., Shirakawa, T., Mitsugi, K., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., 6 1 2018, : : Medicine (United States). 97, 25, e11042.

研究成果: Contribution to journalArticle

1 引用 (Scopus)
2015

HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide after Busulfan-Containing Reduced-Intensity Conditioning

on behalf of the Japan Study Group for Cell Therapy and Transplantation, 9 1 2015, : : Biology of Blood and Marrow Transplantation. 21, 9, p. 1646-1652 7 p.

研究成果: Contribution to journalArticle

43 引用 (Scopus)
2016

Mogamulizumab Treatment Prior to Allogeneic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-versus-Host Disease

Sugio, T., Kato, K., Aoki, T., Ohta, T., Saito, N., Yoshida, S., Kawano, I., Henzan, H., Kadowaki, M., Takase, K., Muta, T., Miyawaki, K., Yamauchi, T., Shima, T., Takashima, S., Mori, Y., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H. および6人, Ogawa, R., Ohno, Y., Eto, T., Kamimura, T., Miyamoto, T. & Akashi, K., 9 1 2016, : : Biology of Blood and Marrow Transplantation. 22, 9, p. 1608-1614 7 p.

研究成果: Contribution to journalArticle

28 引用 (Scopus)
2015

Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma

Kiyasu, J., Miyoshi, H., Hirata, A., Arakawa, F., Ichikawa, A., Niino, D., Sugita, Y., Yufu, Y., Choi, I., Abe, Y., Uike, N., Nagafuji, K., Okamura, T., Akashi, K., Takayanagi, R., Shiratsuchi, M. & Ohshima, K., 11 5 2015, : : Blood. 126, 19, p. 2193-2201 9 p.

研究成果: Contribution to journalArticle

228 引用 (Scopus)
2011

Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis

Shimoda, S., Harada, K., Niiro, H., Shirabe, K., Taketomi, A., Maehara, Y., Tsuneyama, K., Nakanuma, Y., Leung, P., Ansari, A. A., Gershwin, M. E. & Akashi, K., 4 2011, : : Hepatology. 53, 4, p. 1270-1281 12 p.

研究成果: Contribution to journalArticle

86 引用 (Scopus)
2017

Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation

Suetsugu, K., Ikesue, H., Miyamoto, T., Shiratsuchi, M., Yamamoto-Taguchi, N., Tsuchiya, Y., Matsukawa, K., Uchida, M., Watanabe, H., Akashi, K. & Masuda, S., 3 1 2017, : : International journal of hematology. 105, 3, p. 361-368 8 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)
2018
3 引用 (Scopus)
2016

Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis

Hisamoto, S., Shimoda, S., Harada, K., Iwasaka, S., Onohara, S., Chong, Y., Nakamura, M., Bekki, Y., Yoshizumi, T., Ikegami, T., Maehara, Y., He, X. S., Gershwin, M. E. & Akashi, K., 12 1 2016, : : Journal of Autoimmunity. 75, p. 150-160 11 p.

研究成果: Contribution to journalArticle

28 引用 (Scopus)

Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females

Kyushu Sapporo SLE (KYSS) Study Group, 2016, : : International Medical Journal. 23, 5, p. 466-469 4 p.

研究成果: Contribution to journalArticle

2017

Assessment of erythrocyte deformability in an obese case of chronic thromboembolic pulmonary hypertension

Yoda, S., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., 1 1 2017, : : Journal of Biorheology. 31, 2, p. 57-60 4 p.

研究成果: Contribution to journalArticle

2011

Modulation of CD4+ T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis

Hashimoto, N., Shimoda, S., Kawanaka, H., Tsuneyama, K., Uehara, H., Akahoshi, T., Kinjo, N., Taketomi, A., Shirabe, K., Akashi, K., Lleo, A., Ansari, A. A., Gershwin, M. E. & Maehara, Y., 8 2011, : : Clinical and Experimental Immunology. 165, 2, p. 243-250 8 p.

研究成果: Contribution to journalArticle

26 引用 (Scopus)
2015

Dietary patterns and the risk of systemic lupus erythematosus in a Japanese population: The Kyushu Sapporo SLE (KYSS) Study

the Kyushu Sapporo SLE (KYSS) Study Group, 1 1 2015, : : International Medical Journal. 22, 3, p. 110-115 6 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)
2014
18 引用 (Scopus)
2019

Myeloablative and reduced-intensity conditioning in HLA-haploidentical peripheral blood stem cell transplantation using post-transplant cyclophosphamide

on behalf of the Japan Study Group for Cell Therapy and Transplantation (JSCT), 3 1 2019, : : Bone Marrow Transplantation. 54, 3, p. 432-441 10 p.

研究成果: Contribution to journalArticle

13 引用 (Scopus)
2018
3 引用 (Scopus)
2019

Risk of secondary primary malignancies in multiple myeloma patients with or without autologous stem cell transplantation

For the Fukuoka Blood and Marrow Transplantation Group, 1 22 2019, : : International journal of hematology. 109, 1, p. 98-106 9 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)
2011

Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus

Furukawa, M., Kiyohara, C., Tsukamoto, H., Mitoma, H., Kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T., Akashi, K., Harada, M. & Horiuchi, T., 3 2011, : : Rheumatology International. 31, 3, p. 365-376 12 p.

研究成果: Contribution to journalArticle

10 引用 (Scopus)

Analysis of immune reconstitution after autologous CD34 + stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 + t cells

Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., 5 2011, : : Rheumatology. 50, 5, p. 944-952 9 p., keq414.

研究成果: Contribution to journalArticle

37 引用 (Scopus)
2018

Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer

Makiyama, A., Arimizu, K., Hirano, G., Makiyama, C., Matsushita, Y., Shirakawa, T., Ohmura, H., Komoda, M., Uchino, K., Inadomi, K., Arita, S., Ariyama, H., Kusaba, H., Shinohara, Y., Kuwayama, M., Kajitani, T., Oda, H., Esaki, T., Akashi, K. & Baba, E., 5 1 2018, : : Gastric Cancer. 21, 3, p. 464-472 9 p.

研究成果: Contribution to journalArticle

9 引用 (Scopus)
2011

Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis

Yabuuchi, H., Matsuo, Y., Tsukamoto, H., Sunami, S., Kamitani, T., Sakai, S., Hatakenaka, M., Nagafuji, K., Horiuchi, T., Harada, M., Akashi, K. & Honda, H., 8 2011, : : European Journal of Radiology. 79, 2, p. e74-e79

研究成果: Contribution to journalArticle

7 引用 (Scopus)
2016

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., 3 2016, : : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

研究成果: Contribution to journalArticle

16 引用 (Scopus)
2017

Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, : : Nucleic acids research. 45, 15, p. 8758-8772 15 p.

研究成果: Contribution to journalArticle

11 引用 (Scopus)
2018

Evaluation of the dose and efficacy of ruxolitinib in Japanese patients with myelofibrosis

Kirito, K., Okamoto, S., Ohishi, K., Tauchi, T., Handa, H., Saito, S., Takenaka, K., Shimoda, K., Oritani, K., Akashi, K., Okada, H., Amagasaki, T., Suzuki, K., Yonezu, T. & Komatsu, N., 1 1 2018, : : International journal of hematology. 107, 1, p. 92-97 6 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Efficacy and safety of switching to nilotinib in patients with CML-CP in major molecular response to imatinib: results of a multicenter phase II trial (NILSw trial)

Ishikawa, J., Matsumura, I., Kawaguchi, T., Kuroda, J., Nakamae, H., Miyamoto, T., Matsuoka, K. I., Shibayama, H., Hino, M., Hirase, C., Kamimura, T., Shimose, T., Akashi, K. & Kanakura, Y., 5 1 2018, : : International journal of hematology. 107, 5, p. 535-540 6 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)
2015

A multinational, open-label, phase 2 study of ruxolitinib in Asian patients with myelofibrosis: Japanese subset analysis

Oritani, K., Okamoto, S., Tauchi, T., Saito, S., Ohishi, K., Handa, H., Takenaka, K., Gopalakrishna, P., Amagasaki, T., Ito, K. & Akashi, K., 3 6 2015, : : International journal of hematology. 101, 3, p. 295-304 10 p.

研究成果: Contribution to journalArticle

13 引用 (Scopus)
2019

Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Tominaga, K., Minato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E. I., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K. I., Tojo, A. および1人, Gotoh, N., 1 8 2019, : : Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 625-630 6 p.

研究成果: Contribution to journalArticle

6 引用 (Scopus)
2017

Pancreatic acinar cell carcinoma presenting with panniculitis, successfully treated with FOLFIRINOX: A case report

Yoshihiro, T., Nio, K., Tsuchihashi, K., Ariyama, H., Kohashi, K., Tsuruta, N., Hanamura, F., Inadomi, K., Ito, M., Sagara, K., Okumura, Y., Nakano, M., Arita, S., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., 6 2017, : : Molecular and Clinical Oncology. 6, 6, p. 866-870 5 p.

研究成果: Contribution to journalArticle

2018

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., 12 2018, : : Cancer Science. 109, 12, p. 3874-3882 9 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Long-term efficacy of infliximab treatment and the predictors of treatment outcomes in patients with refractory uveitis associated with Behçet's disease

Ueda, S., Akahoshi, M., Takeda, A., Inoue, Y., Omoto, A., Ayano, M., Kimoto, Y., Mitoma, H., Arinobu, Y., Niiro, H., Tsukamoto, H., Horiuchi, T., Hikita, S-I., Fukuhara, T., Ishibashi, T., Sonoda, K-H. & Akashi, K., 3 2018, : : European journal of rheumatology. 5, 1, p. 9-15 7 p.

研究成果: Contribution to journalArticle

2017

Systemic chemotherapy with pronounced efficacy and neutropenia in a granulocyte-colony stimulating factor-producingadvanced gastric neuroendocrine carcinoma

Tsuruta, N., Takayoshi, K., Arita, S., Aikawa, T., Ariyama, H., Kusaba, H., Ohuchida, K., Nagai, E., Kohashi, K., Hirahashi, M., Inadomi, K., Tanaka, M., Sagara, K., Okumura, Y., Nio, K., Nakano, M., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., 2017, : : Oncology Letters. 14, 2, p. 1500-1504 5 p.

研究成果: Contribution to journalArticle

2019
5 引用 (Scopus)
2011

Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

Kikushige, Y., Ishikawa, F., Miyamoto, T., Shima, T., Urata, S., Yoshimoto, G., Mori, Y., Iino, T., Yamauchi, T., Eto, T., Niiro, H., Iwasaki, H., Takenaka, K. & Akashi, K., 8 16 2011, : : Cancer Cell. 20, 2, p. 246-259 14 p.

研究成果: Contribution to journalArticle

176 引用 (Scopus)
2015

TYK2 Promoter Variant and Diabetes Mellitus in the Japanese

Nagafuchi, S., Kamada-Hibio, Y., Hirakawa, K., Tsutsu, N., Minami, M., Okada, A., Kai, K., Teshima, M., Moroishi, A., Murakami, Y., Umeno, Y., Yokogawa, Y., Kogawa, K., Izumi, K., Anzai, K., Iwakiri, R., Hamaguchi, K., Sasaki, N., Nohara, S., Yoshida, E. および16人, Harada, M., Akashi, K., Yanase, T., Ono, J., Okeda, T., Fujimoto, R., Ihara, K., Hara, T., Kikuchi, Y., Iwase, M., Kitazono, T., Kojima, F., Kono, S., Kurisaki, H., Kondo, S. & Katsuta, H., 7 1 2015, : : EBioMedicine. 2, 7, p. 744-749 6 p.

研究成果: Contribution to journalArticle

20 引用 (Scopus)

Natural killer cells regulate T cell immune responses in primary biliary cirrhosis

Shimoda, S., Hisamoto, S., Harada, K., Iwasaka, S., Chong, Y., Nakamura, M., Bekki, Y., Yoshizumi, T., Shirabe, K., Ikegami, T., Maehara, Y., He, X. S., Gershwin, M. E. & Akashi, K., 12 1 2015, : : Hepatology. 62, 6, p. 1817-1827 11 p.

研究成果: Contribution to journalArticle

37 引用 (Scopus)
2017

Recurrent subcutaneous sweet’s disease in a myelofibrosis patient treated with ruxolitinib before allogeneic stem cell transplantation

Sakoda, T., Kanamitsu, Y., Mori, Y., Sasaki, K., Yonemitsu, E., Nagae, K., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Miyamoto, T., Furue, M., Iwasaki, H. & Akashi, K., 2017, : : Internal Medicine. 56, 18, p. 2481-2485 5 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)
2018

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Uchi, H., Ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., 10 2018, : : Cancer Science. 109, 10, p. 3032-3042 11 p.

研究成果: Contribution to journalArticle

15 引用 (Scopus)
2016

Efficacy and safety analysis of chemotherapy for advanced colitis-associated colorectal cancer in Japan

Nio, K., Higashi, D., Kumagai, H., Arita, S., Shirakawa, T., Nakashima, K., Shibata, Y., Esaki, M., Manabe, T., Nagai, S., Ueki, T., Nakano, M., Ariyama, H., Kusaba, H., Hirahashi, M., Oda, Y., Esaki, T., Mitsugi, K., Futami, K., Akashi, K. および1人, Baba, E., 6 2016, : : Anti-cancer drugs. 27, 5, p. 457-463 7 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)
2015

Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

Tanaka, A., Tsukamoto, H., Mitoma, H., Kiyohara, C., Ueda, N., Ayano, M., Ohta, S. I., Kimoto, Y., Akahoshi, M., Arinobu, Y., Niiro, H., Tada, Y., Horiuchi, T. & Akashi, K., 12 14 2015, : : Arthritis Research and Therapy. 17, 1, 27.

研究成果: Contribution to journalArticle

8 引用 (Scopus)
2017

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., 6 1 2017, : : Lung Cancer. 108, p. 75-82 8 p.

研究成果: Contribution to journalArticle

21 引用 (Scopus)
2015
1 引用 (Scopus)
2018

Development of a 2-h suicide prevention program for medical staff including nurses and medical residents: A two-center pilot trial

Nakagami, Y., Kubo, H., Katsuki, R., Sakai, T., Sugihara, G., Naito, C., Oda, H., Hayakawa, K., Suzuki, Y., Fujisawa, D., Hashimoto, N., Kobara, K., Cho, T., Kuga, H., Takao, K., Kawahara, Y., Matsumura, Y., Murai, T., Akashi, K., Kanba, S. および2人, Otsuka, K. & Kato, T. A., 1 1 2018, : : Journal of Affective Disorders. 225, p. 569-576 8 p.

研究成果: Contribution to journalArticle

11 引用 (Scopus)
2017

Metastatic esophageal cancer presenting as shock by injury of vagus nerve mimicking baroreceptor reflex: A case report

Tsuchihashi, K., Yoshihiro, T., Aikawa, T., Nio, K., Takayoshi, K., Yokoyama, T., Fukata, M., Arita, S., Ariyama, H., Shimizu, Y., Yoshida, Y., Torisu, T., Esaki, M., Odashiro, K., Kusaba, H., Akashi, K. & Baba, E., 12 1 2017, : : Medicine (United States). 96, 49, e8987.

研究成果: Contribution to journalArticle

2018

Effect of ruxolitinib therapy on the quality-of-life of Japanese patients with myelofibrosis

Oritani, K., Ohishi, K., Okamoto, S., Kirito, K., Komatsu, N., Tauchi, T., Handa, H., Saito, S., Takenaka, K., Shimoda, K., Okada, H., Amagasaki, T., Wakase, S., Shimozuma, K. & Akashi, K., 1 4 2018, : : Current Medical Research and Opinion. 34, 3, p. 531-537 7 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)
2011

[Specific surface markers of AML-leukemic stem cells].

Kikushige, Y., Miyamoto, T. & Akashi, K., 7 1 2011, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 52, 7, p. 531-534 4 p.

研究成果: Contribution to journalReview article

2015

Recent advances in therapeutic approaches for adult T-cell leukemia/lymphoma

Kato, K. & Akashi, K., 12 14 2015, : : Viruses. 7, 12, p. 6604-6612 9 p.

研究成果: Contribution to journalReview article

25 引用 (Scopus)
2014

Evaluation of clinical performance of the major BCR-ABL mRNA detection kit which enables conversion to international standard scale using the reference material calibrator.

Miyamura, K., Okamoto, S., Usui, N., Hino, M., Akashi, K., Nakaseko, T., Takahashi, N., Nakatani, K., Takahashi, K., Nobori, T. & Naoe, T., 5 2014, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 55, 5, p. 534-540 7 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)
2016

Cord blood transplantation following reduced-intensity conditioning for adult-onset inherited hemophagocytic lymphohistiocytosis

Kuriyama, T., Kato, K., Sakamoto, K., Hayashi, M., Takashima, S., Mori, Y., Takenaka, K., Iwasaki, H., Teshima, T., Harada, N., Nagafuji, K., Miyamoto, T. & Akashi, K., 3 15 2016, : : Internal Medicine. 55, 6, p. 667-671 5 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)