研究成果を検索

検索結果

• 2017

  Bongkrekic acid induces selective cytotoxicity in tumor cells, revealed by CCK-8

  Kano, A., Kamita, M. K., Iwasaki, T. & Shindo, M., 9 2017, In: Evergreen. 4, 2-3, p. 23-27 5 p.

  研究成果: Contribution to journal › Article › 査読

  • Bongkrekic Acid
  • Cytotoxicity
  • cytotoxicity
  • tumor
  • Tumors
  2 被引用数 (Scopus)

• Macrophage colony-stimulating factor mediates its immunosuppressive activity through the emerging myeloid cells during tumor progression

  Kamita, M., Shindo, M. & Kano, A., 9 2017, In: Evergreen. 4, 2-3, p. 18-22 5 p.

  研究成果: Contribution to journal › Article › 査読

  • Macrophages
  • Macrophage Colony-Stimulating Factor
  • tumor
  • Tumors
  • Immunosuppressive Agents
• 2016

  Synthesis of fluorescent molecular probes based on cis-cinnamic acid and molecular imaging of lettuce roots

  Fukuda, H., Nishikawa, K., Fukunaga, Y., Okuda, K., Kodama, K., Matsumoto, K., Kano, A. & Shindo, M., 2016, In: Tetrahedron. 72, 41, p. 6492-6498 7 p.

  研究成果: Contribution to journal › Article › 査読

  • Molecular imaging
  • NSC 153174
  • Lettuce
  • cinnamic acid
  • Azo Compounds
  5 被引用数 (Scopus)
• 2015

  Efficient Total Synthesis of Bongkrekic Acid and Apoptosis Inhibitory Activity of Its Analogues

  Matsumoto, K., Suyama, M., Fujita, S., Moriwaki, T., Sato, Y., Aso, Y., Muroshita, S., Matsuo, H., Monda, K., Okuda, K., Abe, M., Fukunaga, H., Kano, A. & Shindo, M., 8 1 2015, In: Chemistry - A European Journal. 21, 32, p. 11590-11602 13 p.

  研究成果: Contribution to journal › Article › 査読

  • Bongkrekic Acid
  • Cell death
  • Acids
  • Apoptosis
  • Carboxylic acids
  11 被引用数 (Scopus)

• Tumor cell secretion of soluble factor(s) for specific immunosuppression

  Kano, A., 3 9 2015, In: Scientific reports. 5, 8913.

  研究成果: Contribution to journal › Article › 査読

  • Immunosuppression
  • Conditioned Culture Medium
  • Neoplasms
  • Isogeneic Transplantation
  • Immune Evasion
  33 被引用数 (Scopus)
• 2013

  Design of UCST polymers for chilling capture of proteins

  Shimada, N., Nakayama, M., Kano, A. & Maruyama, A., 5 13 2013, In: Biomacromolecules. 14, 5, p. 1452-1457 6 p.

  研究成果: Contribution to journal › Article › 査読

  • Chilling
  • Proteins
  • Polymers
  • Derivatives
  • Anhydrides
  55 被引用数 (Scopus)

• Effective tumor treatment by VEGF siRNA complexed with hydrophobic poly(amino acid)-modified polyethylenimine

  Chen, J., Tian, H., Dong, X., Guo, Z., Jiao, Z., Li, F., Kano, A., Maruyama, A. & Chen, X., 10 2013, In: Macromolecular Bioscience. 13, 10, p. 1438-1446 9 p.

  研究成果: Contribution to journal › Article › 査読

  • polyethylenimine-poly(gamma-benzylglutamate)
  • Polyethyleneimine
  • Amino acids
  • Polyetherimides
  • Tumors
  25 被引用数 (Scopus)

• Polyelectrolyte-assisted transconformation of a stem-loop DNA

  Du, J., Wu, L., Shimada, N., Kano, A. & Maruyama, A., 2013, In: Chemical Communications. 49, 5, p. 475-477 3 p.

  研究成果: Contribution to journal › Article › 査読

  • Dimerization
  • Polyelectrolytes
  • Dimers
  • Copolymers
  • DNA
  8 被引用数 (Scopus)

• Reversibly crosslinked polymeric micelles formed by autonomously exchangeable dynamic covalent bonds

  Nishihara, M., Imato, K., Irie, A., Kanehara, T., Kano, A., Maruyama, A., Takahara, A. & Otsuka, H., 2013, In: Chemistry Letters. 42, 4, p. 377-379 3 p.

  研究成果: Contribution to journal › Article › 査読

  • Covalent bonds
  • Micelles
  • Block copolymers
  • Oxygen
  • Crosslinking
  14 被引用数 (Scopus)

• Tumor delivery of Photofrin® by PLL-g-PEG for photodynamic therapy

  Kano, A., Taniwaki, Y., Nakamura, I., Shimada, N., Moriyama, K. & Maruyama, A., 5 10 2013, In: Journal of Controlled Release. 167, 3, p. 315-321 7 p.

  研究成果: Contribution to journal › Article › 査読

  • polylysine-graft-(poly(ethylene glycol))
  • Dihematoporphyrin Ether
  • Photochemotherapy
  • Neoplasms
  • Ethylene Glycol
  22 被引用数 (Scopus)
• 2012

  Dual crosslinked hydrogel nanoparticles by nanogel bottom-up method for sustained-release delivery

  Shimoda, A., Sawada, S. I., Kano, A., Maruyama, A., Moquin, A., Winnik, F. M. & Akiyoshi, K., 11 1 2012, In: Colloids and Surfaces B: Biointerfaces. 99, p. 38-44 7 p.

  研究成果: Contribution to journal › Article › 査読

  • NanoGel
  • Hydrogels
  • Polyethylene glycols
  • hydrolysis
  • esters
  44 被引用数 (Scopus)

• α-amino acid pendant polymers as endosomal pH-responsive gene carriers

  Wada, T., Kano, A., Shimada, N. & Maruyama, A., 3 1 2012, In: Macromolecular Research. 20, 3, p. 302-308 7 p.

  研究成果: Contribution to journal › Article › 査読

  • Amino acids
  • Genes
  • Polymers
  • Amino Acids
  • Lysine
  9 被引用数 (Scopus)
• 2011

  Cationic comb-type copolymers do not cause collapse but shrinkage of DNA molecules

  Sonda, N., Hirano, M., Shimada, N., Kano, A., Kidoaki, S. & Maruyama, A., 2011, In: Chemistry Letters. 40, 3, p. 250-251 2 p.

  研究成果: Contribution to journal › Article › 査読

  • Copolymers
  • Molecules
  • DNA
  • Polylysine
  • Graft copolymers
  5 被引用数 (Scopus)

• DNA assembly and re-assembly activated by cationic comb-type copolymer

  Moriyama, R., Shimada, N., Kano, A. & Maruyama, A., 3 2011, In: Biomaterials. 32, 9, p. 2351-2358 8 p.

  研究成果: Contribution to journal › Article › 査読

  • Comb and Wattles
  • Copolymers
  • DNA
  • Polyelectrolytes
  • polycations
  17 被引用数 (Scopus)

• Enhanced cell uptake via non-covalent decollation of a single-walled carbon nanotube-DNA hybrid with polyethylene glycol-grafted poly(l-lysine) labeled with an Alexa-dye and its efficient uptake in a cancer cell

  Fujigaya, T., Yamamoto, Y., Kano, A., Maruyama, A. & Nakashima, N., 10 1 2011, In: Nanoscale. 3, 10, p. 4352-4358 7 p.

  研究成果: Contribution to journal › Article › 査読

  • Single-walled carbon nanotubes (SWCN)
  • Polyethylene glycols
  • Dyes
  • Polyethylene Glycols
  • DNA
  15 被引用数 (Scopus)

• Evaluation of polyanion-coated biodegradable polymeric micelles as drug delivery vehicles

  Ohya, Y., Takeda, S., Shibata, Y., Ouchi, T., Kano, A., Iwata, T., Mochizuki, S., Taniwaki, Y. & Maruyama, A., 10 10 2011, In: Journal of Controlled Release. 155, 1, p. 104-110 7 p.

  研究成果: Contribution to journal › Article › 査読

  • polyanions
  • Micelles
  • Hyaluronic Acid
  • Pharmaceutical Preparations
  • carboxymethyl dextran
  36 被引用数 (Scopus)

• Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA

  Kano, A., Moriyama, K., Yamano, T., Nakamura, I., Shimada, N. & Maruyama, A., 1 5 2011, In: Journal of Controlled Release. 149, 1, p. 2-7 6 p.

  研究成果: Contribution to journal › Article › 査読

  • (O-methylpoly(ethylene glycol)-O'-succinyl)-N-epsilon-poly(L-lysine)
  • Blood Circulation
  • Lysine
  • Small Interfering RNA
  • Neoplasms
  53 被引用数 (Scopus)

• In vitro and in vivo gene delivery using polyethylenimine-poly(hydroxyethyl glutamine) as a non-viral carrier.

  Chen, J., Tian, H., Kano, A., Maruyama, A., Chen, X. & Park, T. G., 11 30 2011, In: Journal of controlled release : official journal of the Controlled Release Society. 152 Suppl 1, p. e134-136

  研究成果: Contribution to journal › Article › 査読
  2 被引用数 (Scopus)

• Nuclear localization and antisense effect of PNA internalized by ASGP-R-mediated endocytosis with protein/DNA conjugates

  Ishihara, T., Kano, A., Obara, K., Saito, M., Chen, X., Park, T. G., Akaike, T. & Maruyama, A., 10 10 2011, In: Journal of Controlled Release. 155, 1, p. 34-39 6 p.

  研究成果: Contribution to journal › Article › 査読

  • Asialoglycoprotein Receptor
  • Peptide Nucleic Acids
  • Endocytosis
  • DNA
  • Proteins
  17 被引用数 (Scopus)

• Preparation of Cationic Comb-Type Copolymer having Tetra-Alkylammonium Groups and its Interaction with DNA

  Moriyama, R., Mochida, J., Yamayoshi, A., Shimada, N., Kano, A. & Maruyama, A., 12 2011, In: Current Nanoscience. 7, 6, p. 979-983 5 p.

  研究成果: Contribution to journal › Article › 査読

  • poly(lysine)-graft-dextran
  • Comb and Wattles
  • Copolymers
  • Phase locked loops
  • Dextran
  1 被引用数 (Scopus)

• The role of cationic comb-type copolymers in chaperoning DNA annealing

  Moriyama, R., Shimada, N., Kano, A. & Maruyama, A., 10 2011, In: Biomaterials. 32, 30, p. 7671-7676 6 p.

  研究成果: Contribution to journal › Article › 査読

  • Comb and Wattles
  • Copolymers
  • DNA
  • Nucleic Acids
  • Annealing
  12 被引用数 (Scopus)

• Ureido-derivatized polymers based on both poly(allylurea) and poly(l -citrulline) exhibit UCST-type phase transition behavior under physiologically relevant conditions

  Shimada, N., Ino, H., Maie, K., Nakayama, M., Kano, A. & Maruyama, A., 10 10 2011, In: Biomacromolecules. 12, 10, p. 3418-3422 5 p.

  研究成果: Contribution to journal › Article › 査読

  • Citrulline
  • Phase transitions
  • Polymers
  • Ionic strength
  • Phase separation
  110 被引用数 (Scopus)