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[Molecular-targeted drug for non-small cell lung cancer].

Okamoto, I., 1 1 2012, : : Unknown Journal. 70 Suppl 8, p. 438-442 5 p.

研究成果: ジャーナルへの寄稿記事

Fusion Oncogene Proteins
Anilides
Molecular Targeted Therapy
Pyrimidines
Non-Small Cell Lung Carcinoma

18F-FDG uptake in PET/CT is a potential predictive biomarker of response to anti-PD-1 antibody therapy in non-small cell lung cancer

Takada, K., Toyokawa, G., Yoneshima, Y., Tanaka, K., Okamoto, I., Shimokawa, M., Wakasu, S., Haro, A., Osoegawa, A., Tagawa, T., Oda, Y., Nakanishi, Y. & Mori, M., 12 1 2019, : : Scientific reports. 9, 1, 13362.

研究成果: ジャーナルへの寄稿記事

公開
Fluorodeoxyglucose F18
Non-Small Cell Lung Carcinoma
Cell Death
Biomarkers
Antibodies
5 引用 (Scopus)

A Clinicopathological and Prognostic Analysis of PD-L2 Expression in Surgically Resected Primary Lung Squamous Cell Carcinoma

Matsubara, T., Takada, K., Azuma, K., Takamori, S., Toyokawa, G., Haro, A., Osoegawa, A., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., 6 15 2019, : : Annals of Surgical Oncology. 26, 6, p. 1925-1933 9 p.

研究成果: ジャーナルへの寄稿記事

Squamous Cell Carcinoma
Ligands
Lung
CD274 Antigen
Immunotherapy
364 引用 (Scopus)

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab

Yonesaka, K., Zejnullahu, K., Okamoto, I., Satoh, T., Cappuzzo, F., Souglakos, J., Ercan, D., Rogers, A., Roncalli, M., Takeda, M., Fujisaka, Y., Philips, J., Shimizu, T., Maenishi, O., Cho, Y., Sun, J., Destro, A., Taira, K., Takeda, K., Okabe, T. および12人, Swanson, J., Itoh, H., Takada, M., Lifshits, E., Okuno, K., Engelman, J. A., Shivdasani, R. A., Nishio, K., Fukuoka, M., Varella-Garcia, M., Nakagawa, K. & Jänne, P. A., 9 7 2011, : : Science Translational Medicine. 3, 99

研究成果: ジャーナルへの寄稿記事

Antibodies
Neuregulin-1
Therapeutics
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.

Yonesaka, K., Zejnullahu, K., Okamoto, I., Satoh, T., Cappuzzo, F., Souglakos, J., Ercan, D., Rogers, A., Roncalli, M., Takeda, M., Fujisaka, Y., Philips, J., Shimizu, T., Maenishi, O., Cho, Y., Sun, J., Destro, A., Taira, K., Takeda, K., Okabe, T. および12人, Swanson, J., Itoh, H., Takada, M., Lifshits, E., Okuno, K., Engelman, J. A., Shivdasani, R. A., Nishio, K., Fukuoka, M., Varella-Garcia, M., Nakagawa, K. & Jänne, P. A., 9 7 2011, : : Science Translational Medicine. 3, 99

研究成果: ジャーナルへの寄稿記事

Antibodies
Neuregulin-1
Therapeutics
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
100 引用 (Scopus)

Activation of HER family signaling as a mechanism of acquired resistance to ALK inhibitors in EML4-ALK-positive non-small cell lung cancer

Tanizaki, J., Okamoto, I., Okabe, T., Sakai, K., Tanaka, K., Hayashi, H., Kaneda, H., Takezawa, K., Kuwata, K., Yamaguchi, H., Hatashita, E., Nishio, K. & Nakagawa, K., 11 15 2012, : : Clinical Cancer Research. 18, 22, p. 6219-6226 8 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Epidermal Growth Factor
Protein-Tyrosine Kinases
Lung Neoplasms
Epidermal Growth Factor Receptor
45 引用 (Scopus)

Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer

Kaneda, H., Arao, T., Matsumoto, K., De Velasco, M. A., Tamura, D., Aomatsu, K., Kudo, K., Sakai, K., Nagai, T., Fujita, Y., Tanaka, K., Yanagihara, K., Yamada, Y., Okamoto, I., Nakagawa, K. & Nishio, K., 10 11 2011, : : British journal of cancer. 105, 8, p. 1210-1217 8 p.

研究成果: ジャーナルへの寄稿記事

Stomach Neoplasms
Endothelial Cells
Human Umbilical Vein Endothelial Cells
Growth
Neoplasms
38 引用 (Scopus)

Addition of bevacizumab enhances antitumor activity of erlotinib against non-small cell lung cancer xenografts depending on VEGF expression

Li, H., Takayama, K., Wang, S., Shiraishi, Y., Gotanda, K., Harada, T., Furuyama, K., Iwama, E., Ieiri, I., Okamoto, I. & Nakanishi, Y., 10 9 2014, : : Cancer chemotherapy and pharmacology. 74, 6, p. 1297-1305 9 p.

研究成果: ジャーナルへの寄稿記事

Heterografts
Non-Small Cell Lung Carcinoma
Vascular Endothelial Growth Factor A
Cells
Tumors
53 引用 (Scopus)

Afatinib versus cisplatin plus pemetrexed in Japanese patients with advanced non-small cell lung cancer harboring activating EGFR mutations: Subgroup analysis of LUX-Lung 3

Kato, T., Yoshioka, H., Okamoto, I., Yokoyama, A., Hida, T., Seto, T., Kiura, K., Massey, D., Seki, Y. & Yamamoto, N., 9 1 2015, : : Cancer Science. 106, 9, p. 1202-1211 10 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
Non-Small Cell Lung Carcinoma
Cisplatin
Lung
Mutation
13 引用 (Scopus)

Alectinib for Patients with ALK Rearrangement–Positive Non–Small Cell Lung Cancer and a Poor Performance Status (Lung Oncology Group in Kyushu 1401)

Iwama, E., Goto, Y., Murakami, H., Harada, T., Tsumura, S., Sakashita, H., Mori, Y., Nakagaki, N., Fujita, Y., Seike, M., Bessho, A., Ono, M., Okazaki, A., Akamatsu, H., Morinaga, R., Ushijima, S., Shimose, T., Tokunaga, S., Hamada, A., Yamamoto, N. および3人, Nakanishi, Y., Sugio, K. & Okamoto, I., 7 2017, : : Journal of Thoracic Oncology. 12, 7, p. 1161-1166 6 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Lung
Confidence Intervals
Patient Safety
CH5424802
13 引用 (Scopus)

A novel mass spectrometry-based assay for diagnosis of EML4-ALK-positive non-small cell lung cancer

Sakai, K., Okamoto, I., Takezawa, K., Hirashima, T., Kaneda, H., Takeda, M., Matsumoto, K., Kimura, H., Fujita, Y., Nakagawa, K., Arao, T. & Nishio, K., 1 1 2012, : : Journal of Thoracic Oncology. 7, 5, p. 913-918 6 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Mass Spectrometry
Paraffin
Formaldehyde
Fluorescence In Situ Hybridization
2 引用 (Scopus)

Anticancer drug treatment for advanced lung cancer with interstitial lung disease

Otsubo, K., Okamoto, I., Hamada, N. & Nakanishi, Y., 7 2018, : : Respiratory Investigation. 56, 4, p. 307-311 5 p.

研究成果: ジャーナルへの寄稿評論記事

Interstitial Lung Diseases
Lung Neoplasms
Pharmaceutical Preparations
Drug Therapy
Therapeutics
46 引用 (Scopus)

Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib

Yonesaka, K., Hirotani, K., Kawakami, H., Takeda, M., Kaneda, H., Sakai, K., Okamoto, I., Nishio, K., Jänne, P. A. & Nakagawa, K., 2 18 2016, : : Oncogene. 35, 7, p. 878-886 9 p.

研究成果: ジャーナルへの寄稿記事

Neuregulin-1
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Monoclonal Antibodies
Protein-Tyrosine Kinases
59 引用 (Scopus)

Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification

Okamoto, W., Okamoto, I., Arao, T., Kuwata, K., Hatashita, E., Yamaguchi, H., Sakai, K., Yanagihara, K., Nishio, K. & Nakagawa, K., 7 1 2012, : : Molecular Cancer Therapeutics. 11, 7, p. 1557-1564 8 p.

研究成果: ジャーナルへの寄稿記事

Protein-Tyrosine Kinases
Stomach Neoplasms
X-Linked Inhibitor of Apoptosis Protein
Apoptosis
Inhibitor of Apoptosis Proteins
14 引用 (Scopus)

A phase I, pharmacokinetic and pharmacodynamic study of nimotuzumab in Japanese patients with advanced solid tumors

Okamoto, W., Yoshino, T., Takahashi, T., Okamoto, I., Ueda, S., Tsuya, A., Boku, N., Nishio, K., Fukuoka, M., Yamamoto, N. & Nakagawa, K., 11 1 2013, : : Cancer chemotherapy and pharmacology. 72, 5, p. 1063-1071 9 p.

研究成果: ジャーナルへの寄稿記事

Pharmacodynamics
Pharmacokinetics
Epidermal Growth Factor Receptor
Toxicity
Tumors
1 引用 (Scopus)

A phase II study of cisplatin /S-1 in patients with carcinomas of unknown primary site

Tsuya, A., Kurata, T., Tamiya, A., Okamoto, I., Ueda, S., Sakai, D., Sugimoto, N., Matsumoto, K., Goto, I., Yamamoto, N., Fukuoka, M. & Nakagawa, K., 12 1 2013, : : Investigational New Drugs. 31, 6, p. 1568-1572 5 p.

研究成果: ジャーナルへの寄稿記事

Cisplatin
Carcinoma
Combination Drug Therapy
Appointments and Schedules
Febrile Neutropenia
1 引用 (Scopus)

A phase i study of S-1 with concurrent radiotherapy in elderly patients with locally advanced non-small cell lung cancer

Hasegawa, Y., Okamoto, I., Takezawa, K., Miyazaki, M., Tsurutani, J., Yonesaka, K., Morinaga, R., Tsuya, A., Terashima, M., Kudoh, T., Azuma, K., Kurata, T., Nishikawa, T., Fukuoka, M., Nishimura, Y. & Nakagawa, K., 6 1 2013, : : Investigational New Drugs. 31, 3, p. 599-604 6 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Radiotherapy
Thorax
Stomatitis
Pneumonia
1 引用 (Scopus)

A phase I study of split-dose cisplatin and etoposide with concurrent accelerated hyperfractionated thoracic radiotherapy in elderly patients with limited-disease small cell lung cancer

Okamoto, K., Okamoto, I., Takeda, M., Kobayashi, S., Takeda, K., Nakamatsu, K., Nishimura, Y. & Nakagawa, K., 8 2014, : : Japanese journal of clinical oncology. 44, 8, p. 743-748 6 p., hyu071.

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
Etoposide
Cisplatin
Radiotherapy
Thorax
6 引用 (Scopus)

A Randomized Phase II Study Comparing Nivolumab With Carboplatin-Pemetrexed for Patients With EGFR Mutation–Positive Nonsquamous Non–Small-Cell Lung Cancer Who Acquire Resistance to Tyrosine Kinase Inhibitors Not Due to a Secondary T790M Mutation: Rationale and Protocol Design for the WJOG8515L Study

Hayashi, H., Chiba, Y., Sakai, K., Fujita, T., Yoshioka, H., Sakai, D., Kitagawa, C., Naito, T., Takeda, K., Okamoto, I., Mitsudomi, T., Kawakami, Y., Nishio, K., Nakamura, S., Yamamoto, N. & Nakagawa, K., 11 2017, : : Clinical Lung Cancer. 18, 6, p. 719-723 5 p.

研究成果: ジャーナルへの寄稿記事

Pemetrexed
erbB-1 Genes
Carboplatin
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases

Association between peripheral blood markers and immune-related factors on tumor cells in patients with resected primary lung adenocarcinoma

Takada, K., Shimokawa, M., Tanaka, K., Kohashi, K., Haro, A., Osoegawa, A., Tagawa, T., Azuma, K., Okamoto, I., Oda, Y. & Mori, M., 6 2019, : : PloS one. 14, 6, e0217991.

研究成果: ジャーナルへの寄稿記事

公開
Indoleamine-Pyrrole 2,3,-Dioxygenase
Immunologic Factors
adenocarcinoma
Cell death
Tumors

Association of nephrotoxicity during platinum-etoposide doublet therapy with UGT1A1 polymorphisms in small cell lung cancer patients

Anai, S., Iwama, E., Yoneshima, Y., Otsubo, K., Tanaka, K., Nakanishi, Y. & Okamoto, I., 12 2018, : : Lung Cancer. 126, p. 156-161 6 p.

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
Etoposide
Platinum
Alleles
irinotecan
327 引用 (Scopus)

Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer

Azuma, K., Ota, K., Kawahara, A., Hattori, S., Iwama, E., Harada, T., Matsumoto, K., Takayama, K., Takamori, S., Kage, M., Hoshino, T., Nakanishi, Y. & Okamoto, I., 10 1 2014, : : Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 25, 10, p. 1935-1940 6 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Ligands
Mutation
Cell Line
12 引用 (Scopus)

Association of preoperative serum CRP with PD-L1 expression in 508 patients with non-small cell lung cancer: A comprehensive analysis of systemic inflammatory markers

Akamine, T., Takada, K., Toyokawa, G., Kinoshita, F., Matsubara, T., Kozuma, Y., Haratake, N., Takamori, S., Hirai, F., Tagawa, T., Okamoto, T., Yoneshima, Y., Okamoto, I., Shimokawa, M., Oda, Y., Nakanishi, Y. & Maehara, Y., 3 2018, : : Surgical Oncology. 27, 1, p. 88-94 7 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
C-Reactive Protein
Blood Proteins
Ligands
Lymphocytes
29 引用 (Scopus)

Association of the expression of mutant epidermal growth factor receptor protein as determined with mutation-specific antibodies in non-small cell lung cancer with progression-free survival after gefitinib treatment

Azuma, K., Okamoto, I., Kawahara, A., Taira, T., Nakashima, K., Hattori, S., Kinoshita, T., Takeda, M., Nakagawa, K., Takamori, S., Kuwano, M., Ono, M. & Kage, M., 1 2012, : : Journal of Thoracic Oncology. 7, 1, p. 122-127 6 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Disease-Free Survival
Mutation
Antibodies
31 引用 (Scopus)

Bevacizumab beyond disease progression after first-line treatment with bevacizumab plus chemotherapy in advanced nonsquamous non-small cell lung cancer (West Japan Oncology Group 5910L): An open-label, randomized, phase 2 trial

Takeda, M., Yamanaka, T., Seto, T., Hayashi, H., Azuma, K., Okada, M., Sugawara, S., Daga, H., Hirashima, T., Yonesaka, K., Urata, Y., Murakami, H., Saito, H., Kubo, A., Sawa, T., Miyahara, E., Nogami, N., Nakagawa, K., Nakanishi, Y. & Okamoto, I., 4 1 2016, : : Cancer. 122, 7, p. 1050-1059 10 p.

研究成果: ジャーナルへの寄稿記事

docetaxel
Non-Small Cell Lung Carcinoma
Disease Progression
Japan
Drug Therapy
16 引用 (Scopus)

Bilateral ovarian metastasis of non-small cell lung cancer with ALK rearrangement

Fujiwara, A., Higashiyama, M., Kanou, T., Tokunaga, T., Okami, J., Kodama, K., Nishino, K., Tomita, Y. & Okamoto, I., 2 1 2014, : : Lung Cancer. 83, 2, p. 302-304 3 p.

研究成果: ジャーナルへの寄稿記事

Gene Rearrangement
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Fluorescence In Situ Hybridization
anaplastic lymphoma kinase
1 引用 (Scopus)

Bronchoscopic findings for bevacizumab-related pulmonary hemorrhage in advanced non-small cell lung cancer

Okamoto, K., Okamoto, I., Miyazaki, M., Tanaka, K., Kaneda, H. & Nakagawa, K., 10 1 2013, : : Investigational New Drugs. 31, 5, p. 1364-1366 3 p.

研究成果: ジャーナルへの寄稿記事

Bronchoscopy
Non-Small Cell Lung Carcinoma
Hemorrhage
Lung
Hemoptysis

Capecitabine plus cisplatin treatment for advanced gastric cancer in a patient with hepatic impairment secondary to metastases

Kawakami, H., Nishina, S. I., Ueda, S., Kudo, T., Okamoto, W., Kurata, T., Okamoto, I. & Nakagawa, K., 5 1 2012, : : Gastrointestinal Cancer Research. 5, 3, p. 103-105 3 p.

研究成果: ジャーナルへの寄稿記事

Cisplatin
Stomach Neoplasms
Neoplasm Metastasis
Liver
Therapeutics
4 引用 (Scopus)

CD44 variant–dependent regulation of redox balance in EGFR mutation–positive non–small cell lung cancer: A target for treatment

Kawano, Y., Iwama, E., Tsuchihashi, K., Shibahara, D., Harada, T., Tanaka, K., Nagano, O., Saya, H., Nakanishi, Y. & Okamoto, I., 11 2017, : : Lung Cancer. 113, p. 72-78 7 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Oxidation-Reduction
Reactive Oxygen Species
Cisplatin
29 引用 (Scopus)

Characteristics and overall survival of EGFR mutation-positive non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors: A retrospective analysis for 1660 Japanese patients

Inoue, A., Yoshida, K., Morita, S., Imamura, F., Seto, T., Okamoto, I., Nakagawa, K., Yamamoto, N., Muto, S. & Fukuoka, M., 1 1 2016, : : Japanese journal of clinical oncology. 46, 5, p. 462-467 6 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Mutation
Survival
5 引用 (Scopus)

Characteristics of smoking patients with lung cancer with emphysematous bullae

Iwama, E., Okamoto, I., Yabuuchi, H., Takayama, K., Harada, T., Matsuo, Y., Tokunaga, S., Baba, E. & Nakanishi, Y., 1 1 2016, : : Journal of Thoracic Oncology. 11, 9, p. 1586-1590 5 p.

研究成果: ジャーナルへの寄稿記事

Blister
Lung Neoplasms
Smoking
Emphysema
Epidermal Growth Factor
1 引用 (Scopus)

Chronic myelomonocytic leukemia blast crisis in a patient with advanced non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors

Ogata, H., Okamoto, I., Yoshimoto, G., Obara, T., Ijichi, K., Iwama, E., Harada, T., Akashi, K. & Nakanishi, Y., 3 1 2017, : : Respiratory Investigation. 55, 2, p. 181-183 3 p.

研究成果: ジャーナルへの寄稿記事

Leukemia, Myelomonocytic, Chronic
erbB-1 Genes
Blast Crisis
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
10 引用 (Scopus)

Circulating hepatocyte growth factor is correlated with resistance to cetuximab in metastatic colorectal cancer

Yonesaka, K., Satoh, T., Ueda, S., Yoshida, T., Takeda, M., Shimizu, T., Okamoto, I., Nishio, K., Tamura, T. & Nakagawa, K., 3 1 2015, : : Anticancer research. 35, 3, p. 1683-1690 8 p.

研究成果: ジャーナルへの寄稿記事

Hepatocyte Growth Factor
Colorectal Neoplasms
Transforming Growth Factors
Epidermal Growth Factor Receptor
Disease-Free Survival

Clinical benefits associated with first line treatment using afatinib

Iwama, E. & Okamoto, I., 10 20 2015, : : Japanese Journal of Lung Cancer. 55, 6, p. 866-870 5 p.

研究成果: ジャーナルへの寄稿評論記事

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Therapeutics
Mutation
Paronychia
7 引用 (Scopus)

Clinical development of nintedanib for advanced non-small-cell lung cancer

Takeda, M., Okamoto, I. & Nakagawa, K., 11 16 2015, : : Therapeutics and Clinical Risk Management. 11, p. 1701-1706 6 p.

研究成果: ジャーナルへの寄稿評論記事

docetaxel
Non-Small Cell Lung Carcinoma
cancer
Cells
Toxicity
62 引用 (Scopus)
Lung Neoplasms
Central Nervous System
Radiotherapy
Non-Small Cell Lung Carcinoma
Disease Progression
14 引用 (Scopus)

Clinical impact of switching to a second EGFR-TKI after a severe AE related to a first EGFR-TKI in EGFR-mutated NSCLC

Takeda, M., Okamoto, I., Tsurutani, J., Oiso, N., Kawada, A. & Nakagawa, K., 6 1 2012, : : Japanese journal of clinical oncology. 42, 6, p. 528-533 6 p., hys042.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Mutation
Interstitial Lung Diseases
31 引用 (Scopus)

Clinical outcome for EML4-ALK-positive patients with advanced non-small-cell lung cancer treated with first-line platinum-based chemotherapy

Takeda, M., Okamoto, I., Sakai, K., Kawakami, H., Nishio, K. & Nakagawa, K., 11 1 2012, : : Annals of Oncology. 23, 11, p. 2931-2936 6 p., mds124.

研究成果: ジャーナルへの寄稿記事

Platinum
Non-Small Cell Lung Carcinoma
Drug Therapy
Mutation
Oncogene Fusion
12 引用 (Scopus)

Clinical outcomes of thoracic radiotherapy for locally advanced nsclc with EGFR mutations or EML4-ALK rearrangement

Hayashi, H., Okamoto, I., Kimura, H., Sakai, K., Nishimura, Y., Nishio, K. & Nakagawa, K., 10 1 2012, : : Anticancer research. 32, 10, p. 4533-4538 6 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Radiotherapy
Thorax
Non-Small Cell Lung Carcinoma
Mutation
11 引用 (Scopus)

Clinical phase I study of elpamotide, a peptide vaccine for vascular endothelial growth factor receptor 2, in patients with advanced solid tumors

Okamoto, I., Arao, T., Miyazaki, M., Satoh, T., Okamoto, K., Tsunoda, T., Nishio, K. & Nakagawa, K., 12 1 2012, : : Cancer Science. 103, 12, p. 2135-2138 4 p.

研究成果: ジャーナルへの寄稿記事

Vascular Endothelial Growth Factor Receptor-2
Subunit Vaccines
Vaccines
Maximum Tolerated Dose
Neoplasms
13 引用 (Scopus)

Clinical response to crizotinib retreatment after acquisition of drug resistance

Matsuoka, H., Kurata, T., Okamoto, I., Kaneda, H., Tanaka, K. & Nakagawa, K., 7 1 2013, : : Journal of Clinical Oncology. 31, 19

研究成果: ジャーナルへの寄稿記事

Fusion Oncogene Proteins
Serine Endopeptidases
Neoplasm Drug Resistance
Drug Administration Schedule
Antineoplastic Combined Chemotherapy Protocols
2 引用 (Scopus)

Clinical significance of monitoring EGFR mutation in plasma using multiplexed digital PCR in EGFR mutated patients treated with afatinib (West Japan Oncology Group 8114LTR study)

Akamatsu, H., Koh, Y., Okamoto, I., Fujimoto, D., Bessho, A., Azuma, K., Morita, S., Yamamoto, N. & Nakagawa, K., 5 2019, : : Lung Cancer. 131, p. 128-133 6 p.

研究成果: ジャーナルへの寄稿記事

公開
Epidermal Growth Factor Receptor
Japan
Polymerase Chain Reaction
Mutation
Non-Small Cell Lung Carcinoma
7 引用 (Scopus)

Clinical significance of PD-L1 expression in brain metastases from non-small cell lung cancer

Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kinoshita, F., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Mukae, N., Hirai, F., Tagawa, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., 1 2018, : : Anticancer research. 38, 1, p. 553-557 5 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
Cell Death
Neoplasm Metastasis
Ligands
Brain
58 引用 (Scopus)

CNS response to osimertinib versus standard epidermal growth factor receptor tyrosine kinase inhibitors in patients with untreated EGFR-mutated advanced non-small-cell lung cancer

Reungwetwattana, T., Nakagawa, K., Cho, B. C., Cobo, M., Cho, E. K., Bertolini, A., Bohnet, S., Zhou, C., Lee, K. H., Nogami, N., Okamoto, I., Leighl, N., Hodge, R., McKeown, A., Brown, A. P., Rukazenkov, Y., Ramalingam, S. S. & Vansteenkiste, J., 11 20 2018, : : Journal of Clinical Oncology. 36, 33, p. 3290-3297 8 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
osimertinib
Disease-Free Survival
7 引用 (Scopus)

Combined analysis of plasma amphiregulin and heregulin predicts response to cetuximab in metastatic colorectal cancer

Yonesaka, K., Takegawa, N., Satoh, T., Ueda, H., Yoshida, T., Takeda, M., Shimizu, T., Chiba, Y., Okamoto, I., Nishio, K., Tamura, T. & Nakagawa, K., 11 1 2015, : : PloS one. 10, 11, e0143132.

研究成果: ジャーナルへの寄稿記事

Neuregulin-1
colorectal neoplasms
Colorectal Neoplasms
Plasmas
Epidermal Growth Factor Receptor
32 引用 (Scopus)

Combined effect of ALK and MEK inhibitors in EML4-ALK-positive non-small-cell lung cancer cells

Tanizaki, J., Okamoto, I., Takezawa, K., Sakai, K., Azuma, K., Kuwata, K., Yamaguchi, H., Hatashita, E., Nishio, K., Janne, P. A. & Nakagawa, K., 2 14 2012, : : British journal of cancer. 106, 4, p. 763-767 5 p.

研究成果: ジャーナルへの寄稿記事

Mitogen-Activated Protein Kinase Kinases
Non-Small Cell Lung Carcinoma
MAP Kinase Signaling System
Apoptosis
Phosphorylation
4 引用 (Scopus)

Combined therapy with epidermal growth factor receptor tyrosine kinase inhibitors for non–small cell lung cancer

Iwama, E., Nakanishi, Y. & Okamoto, I., 3 4 2018, : : Expert Review of Anticancer Therapy. 18, 3, p. 267-276 10 p.

研究成果: ジャーナルへの寄稿評論記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Mutation
Therapeutics
54 引用 (Scopus)

CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance

Park, K. S., Raffeld, M., Moon, Y. W., Xi, L., Bianco, C., Pham, T., Lee, L. C., Mitsudomi, T., Yatabe, Y., Okamoto, I., Subramaniam, D., Mok, T., Rosell, R., Luo, J., Salomon, D. S., Wang, Y. & Giaccone, G., 7 1 2014, : : Journal of Clinical Investigation. 124, 7, p. 3003-3015 13 p.

研究成果: ジャーナルへの寄稿記事

Non-Small Cell Lung Carcinoma
MicroRNAs
Epithelial-Mesenchymal Transition
Protein-Tyrosine Kinases
Mutation
3 引用 (Scopus)

Current status and future perspectives of cooperative study groups for lung cancer in Japan

Kawano, Y., Okamoto, I., Fukuda, H., Ohe, Y., Nakamura, S., Nakagawa, K., Hotta, K., Kiura, K., Takiguchi, Y., Saka, H., Okamoto, H., Takayama, K., Semba, H., Kobayashi, K., Kenmotsu, H., Tsuboi, M., Yamamoto, N., Nukiwa, T. & Nakanishi, Y., 11 1 2014, : : Respiratory Investigation. 52, 6, p. 339-347 9 p.

研究成果: ジャーナルへの寄稿評論記事

Lung Neoplasms
Japan
Clinical Trials
Research Personnel
Therapeutics
19 引用 (Scopus)

Cystic brain metastasis in non-small-cell lung cancer with ALK rearrangement

Hayashi, H., Okamoto, I., Tanizaki, J., Tanaka, K., Okuda, T., Kato, A., Nishimura, Y. & Nakagawa, K., 1 1 2014, : : Journal of Clinical Oncology. 32, 36, p. e122-e124 A31.

研究成果: ジャーナルへの寄稿記事

Gene Rearrangement
Receptor Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Brain Neoplasms
Cysts