研究成果の検索

検索コンセプト
選択されたフィルター

出版年

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2012
  • 2011

著者

  • Keiichi Nakayama

A 23 gene–based molecular prognostic score precisely predicts overall survival of breast cancer patients

Shimizu, H. & Nakayama, K. I., 8 2019, : : EBioMedicine. 46, p. 150-159 10 p.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

Acetaldehyde administrationinduces salsolinol formation in vivo in the dorsal striatum of Aldh2-knockout and C57BL/6N mice

Ito, A., Jamal, M., Ameno, K., Tanaka, N., Takakura, A., Kawamoto, T., Kitagawa, K., Nakayama, K., Matsumoto, A., Miki, T. & Kinoshita, H., 10 15 2018, : : Neuroscience Letters. 685, p. 50-54 5 p.

研究成果: ジャーナルへの寄稿記事

A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen

Oshikawa, K., Matsumoto, M., Kodama, M., Shimizu, H. & Nakayama, K. I., 3 5 2020, : : Oncogene. 39, 10, p. 2170-2186 17 p.

研究成果: ジャーナルへの寄稿記事

Akt1-mediated Gata3 phosphorylation controls the repression of IFNÎ 3 in memory-type Th2 cells

Hosokawa, H., Tanaka, T., Endo, Y., Kato, M., Shinoda, K., Suzuki, A., Motohashi, S., Matsumoto, M., Nakayama, K. I. & Nakayama, T., 4 7 2016, : : Nature communications. 7, 11289.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

A large-scale targeted proteomics assay resource based on an in vitro human proteome

Matsumoto, M., Matsuzaki, F., Oshikawa, K., Goshima, N., Mori, M., Kawamura, Y., Ogawa, K., Fukuda, E., Nakatsumi, H., Natsume, T., Fukui, K., Horimoto, K., Nagashima, T., Funayama, R., Nakayama, K. & Nakayama, K. I., 2 28 2017, : : Nature Methods. 14, 3, p. 251-258 8 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis

Hoshi, H., Hao, W., Fujita, Y., Funayama, A., Miyauchi, Y., Hashimoto, K., Miyamoto, K., Iwasaki, R., Sato, Y., Kobayashi, T., Miyamoto, H., Yoshida, S., Mori, T., Kanagawa, H., Katsuyama, E., Fujie, A., Kitagawa, K., Nakayama, K. I., Kawamoto, T., Sano, M. および8人, Fukuda, K., Ohsawa, I., Ohta, S., Morioka, H., Matsumoto, M., Chiba, K., Toyama, Y. & Miyamoto, T., 9 1 2012, : : Journal of Bone and Mineral Research. 27, 9, p. 2015-2023 9 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

A strategy for large-scale phosphoproteomics and SRM-based validation of human breast cancer tissue samples

Narumi, R., Murakami, T., Kuga, T., Adachi, J., Shiromizu, T., Muraoka, S., Kume, H., Kodera, Y., Matsumoto, M., Nakayama, K., Miyamoto, Y., Ishitobi, M., Inaji, H., Kato, K. & Tomonaga, T., 11 2 2012, : : Journal of Proteome Research. 11, 11, p. 5311-5322 12 p.

研究成果: ジャーナルへの寄稿記事

67 引用 (Scopus)

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Hosokawa, H., Romero-Wolf, M., Yui, M. A., Ungerbäck, J., Quiloan, M. L. G., Matsumoto, M., Nakayama, K. I., Tanaka, T. & Rothenberg, E. V., 12 1 2018, : : Nature Immunology. 19, 12, p. 1427-1440 14 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Brain-derived neurotrophic factor improves limited exercise capacity in mice with heart failure

Matsumoto, J., Takada, S., Kinugawa, S., Furihata, T., Nambu, H., Kakutani, N., Tsuda, M., Fukushima, A., Yokota, T., Tanaka, S., Takahashi, H., Watanabe, M., Hatakeyama, S., Matsumoto, M., Nakayama, K. I., Otsuka, Y., Sabe, H., Tsutsui, H. & Anzai, T., 1 1 2018, : : Circulation. 138, 18, p. 2064-2066 3 p.

研究成果: ジャーナルへの寄稿レター

4 引用 (Scopus)

CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes

Tane, S., Ikenishi, A., Okayama, H., Iwamoto, N., Nakayama, K. I. & Takeuchi, T., 1 17 2014, : : Biochemical and Biophysical Research Communications. 443, 3, p. 1105-1109 5 p.

研究成果: ジャーナルへの寄稿記事

37 引用 (Scopus)
5 引用 (Scopus)

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T. & Nakayama, K. I., 1 1 2016, : : Nature. 537, 7622, p. 675-679 5 p.

研究成果: ジャーナルへの寄稿記事

82 引用 (Scopus)

Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling

Liu, N., Matsumoto, M., Kitagawa, K., Kotake, Y., Suzuki, S., Shirasawa, S., Nakayama, K. I., Nakanishi, M., Niida, H. & Kitagawa, M., 5 16 2012, : : EMBO Journal. 31, 10, p. 2365-2377 13 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Combined mutation of Apc, Kras, and Tgfbr2 effectively drives metastasis of intestinal cancer

Sakai, E., Nakayama, M., Oshima, H., Kouyama, Y., Niida, A., Fujii, S., Ochiai, A., Nakayama, K. I., Mimori, K., Suzuki, Y., Hong, C. P., Ock, C. Y., Kim, S. J. & Oshima, M., 3 1 2018, : : Cancer Research. 78, 5, p. 1334-1346 13 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Comprehensive identification of substrates for f-box proteins by differential proteomics analysis

Yumimoto, K., Matsumoto, M., Oyamada, K., Moroishi, T. & Nakayama, K. I., 6 1 2012, : : Journal of Proteome Research. 11, 6, p. 3175-3185 11 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Comprehensive study of protein ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M. & Nakayama, K. I., 12 1 2012, : : Seikagaku. 84, 6, p. 479-487 9 p.

研究成果: ジャーナルへの寄稿評論記事

1 引用 (Scopus)

Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma

Yokobori, T., Mimori, K., Iwatsuki, M., Ishii, H., Tanaka, F., Sato, T., Toh, H., Sudo, T., Iwaya, T., Tanaka, Y., Onoyama, I., Kuwano, H., Nakayama, K. I. & Mori, M., 7 1 2012, : : International journal of oncology. 41, 1, p. 253-259 7 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

Corneal antifibrotic switch identified in genetic and pharmacological deficiency of vimentin

Bargagna-Mohan, P., Paranthan, R. R., Hamza, A., Zhan, C. G., Lee, D. M., Kim, K. B., Lau, D. L., Srinivasan, C., Nakayama, K., Nakayama, K., Herrmann, H. & Mohan, R., 1 6 2012, : : Journal of Biological Chemistry. 287, 2, p. 989-1006 18 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Correction: "UV damage-induced phosphorylation of HBO1 triggers CRL4DDB2-mediated degradation to regulate cell proliferation" [Molecular and Cellular Biology 36, 3, (2016) (394-406)] doi 10.1128/MCB.00809-15

Matsunuma, R., Niida, H., Ohhata, T., Kitagawa, K., Sakai, S., Uchida, C., Shiotani, B., Matsumoto, M., Nakayama, K. I., Ogura, H., Shiiya, N. & Kitagawa, M., 4 1 2018, : : Molecular and cellular biology. 38, 7, e00572-17.

研究成果: ジャーナルへの寄稿コメント/討論

Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders

Hagihara, H., Catts, V. S., Katayama, Y., Shoji, H., Takagi, T., Huang, F. L., Nakao, A., Mori, Y., Huang, K. P., Ishii, S., Graef, I. A., Nakayama, K. I., Shannon Weickert, C. & Miyakawa, T., 2 1 2018, : : Neuropsychopharmacology. 43, 3, p. 459-468 10 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Deficiency of Rap1-Binding Protein RAPL Causes Lymphoproliferative Disorders through Mislocalization of p27kip1

Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K. I. & Kinashi, T., 1 28 2011, : : Immunity. 34, 1, p. 24-38 15 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism

Fuster, J. J., González-Navarro, H., Vinué, A., Molina-Sànchez, P., Andrés-Manzano, M. J., Nakayama, K. I., Nakayama, K., Díez-Juan, A., Bernad, A., Rodríguez, C., Martínez-González, J. & Andrés, V., 11 1 2011, : : Arteriosclerosis, thrombosis, and vascular biology. 31, 11, p. 2455-2463 9 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3

Nakayama, S., Yumimoto, K., Kawamura, A. & Nakayama, K. I., 1 1 2018, : : Journal of Biological Chemistry. 293, 15, p. 5705-5714 10 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice

Matsumoto, A., Susaki, E., Onoyama, I., Nakayama, K., Hoshino, M. & Nakayama, K. I., 10 1 2011, : : Molecular and cellular biology. 31, 20, p. 4176-4192 17 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Development of mice without Cip/Kip CDK inhibitors

Tateishi, Y., Matsumoto, A., Kanie, T., Hara, E., Nakayama, K. & Nakayama, K. I., 10 19 2012, : : Biochemical and Biophysical Research Communications. 427, 2, p. 285-292 8 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis

Muto, Y., Moroishi, T., Ichihara, K., Nishiyama, M., Shimizu, H., Eguchi, H., Moriya, K., Koike, K., Mimori, K., Mori, M., Katayama, Y. & Nakayama, K. I., 4 1 2019, : : Journal of Experimental Medicine. 216, 4, p. 950-965 16 p.

研究成果: ジャーナルへの寄稿記事

公開
3 引用 (Scopus)

Drug repositioning in cancer: The current situation in Japan

Masuda, T., Tsuruda, Y., Matsumoto, Y., Uchida, H., Nakayama, K. I. & Mimori, K., 1 1 2020, (受理済み/印刷中) : : Cancer Science.

研究成果: ジャーナルへの寄稿評論記事

公開

Erratum: Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding (Immunity (2018) 48(6) (1119–1134.e7), (S1074761318301936) (10.1016/j.immuni.2018.04.024))

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T. & Rothenberg, E. V., 10 16 2018, : : Immunity. 49, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

1 引用 (Scopus)

Erratum: Regulation of SV40 large T-Antigen stability by reversible acetylation (Oncogene (2006) 25 (7391-7400) DOI: 10.1038/sj.onc.1209731)

Shimazu, T., Komatsu, Y., Nakayama, K. I., Fukazawa, H., Horinouchi, S. & Yoshida, M., 7 17 2014, : : Oncogene. 33, 29, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Erratum: The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis (Cell (2012) 149 (1098-1111))

Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 11 9 2012, : : Cell. 151, 4, p. 913-914 2 p.

研究成果: ジャーナルへの寄稿コメント/討論

4 引用 (Scopus)

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

Muto, Y., Nishiyama, M., Nita, A., Moroishi, T. & Nakayama, K. I., 7 17 2017, : : Nature communications. 8, 16114.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression

Iriuchishima, H., Takubo, K., Matsuoka, S., Onoyama, I., Nakayama, K. I., Nojima, Y. & Suda, T., 2 24 2011, : : Blood. 117, 8, p. 2373-2377 5 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner

Yumimoto, K., Akiyoshi, S., Ueo, H., Sagara, Y., Onoyama, I., Ueo, H., Ohno, S., Mori, M., Mimori, K. & Nakayama, K. I., 2 2 2015, : : Journal of Clinical Investigation. 125, 2, p. 621-635 15 p.

研究成果: ジャーナルへの寄稿記事

52 引用 (Scopus)

Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer

Grim, J. E., Knoblaugh, S. E., Guthrie, K. A., Hagar, A., Swanger, J., Hespelt, J., Delrow, J. J., Small, T., Grady, W. M., Nakayama, K. I. & Clurman, B. E., 6 1 2012, : : Molecular and cellular biology. 32, 11, p. 2160-2167 8 p.

研究成果: ジャーナルへの寄稿記事

50 引用 (Scopus)

Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development

Kitagawa, K., Shibat, K., Matsumoto, A., Matsumoto, M., Ohhata, T., Nakayama, K. I., Niida, H. & Kitagawa, M., 7 2014, : : Molecular and cellular biology. 34, 14, p. 2732-2744 13 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

FBXL12-mediated degradation of ALDH3 is essential for trophoblast differentiation during placental development

Nishiyama, M., Nita, A., Yumimoto, K. & Nakayama, K. I., 11 2015, : : STEM CELLS. 33, 11, p. 3327-3340 14 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

FBXL12 regulates T-cell differentiation in a cell-autonomous manner

Nita, A., Nishiyama, M., Muto, Y. & Nakayama, K., 5 1 2016, : : Genes to Cells. 21, 5, p. 517-524 8 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

FBXL5 inactivation in mouse brain induces aberrant proliferation of neural stem progenitor cells

Yamauchi, T., Nishiyama, M., Moroishi, T., Kawamura, A. & Nakayama, K. I., 4 1 2017, : : Molecular and cellular biology. 37, 8, e00470-16.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

FBXO21 mediates the ubiquitylation and proteasomal degradation of EID1

Watanabe, K., Yumimoto, K. & Nakayama, K. I., 8 1 2015, : : Genes to Cells. 20, 8, p. 667-674 8 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Fbxw7-dependent degradation of notch is required for control of "Stemness" and neuronal-glial differentiation in neural stem cells

Matsumoto, A., Onoyama, I., Sunabori, T., Kageyama, R., Okano, H. & Nakayama, K. I., 4 15 2011, : : Journal of Biological Chemistry. 286, 15, p. 13754-13764 11 p.

研究成果: ジャーナルへの寄稿記事

62 引用 (Scopus)

FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors

Kitade, S., Onoyama, I., Kobayashi, H., Yagi, H., Yoshida, S., Kato, M., Tsunematsu, R., Asanoma, K., Sonoda, K., Wake, N., Hata, K., Nakayama, K. I. & Kato, K., 10 1 2016, : : Cancer Science. 107, 10, p. 1399-1405 7 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver

Onoyama, I., Suzuki, A., Matsumoto, A., Tomita, K., Katagiri, H., Oike, Y., Nakayama, K. & Nakayama, K. I., 1 4 2011, : : Journal of Clinical Investigation. 121, 1, p. 342-354 13 p.

研究成果: ジャーナルへの寄稿記事

75 引用 (Scopus)

Fbxw7 suppresses cancer metastasis by inhibiting niche formation

Yumimoto, K. & Nakayama, K. I., 8 3 2015, : : OncoImmunology. 4, 8

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress

Matsumoto, A., Tateishi, Y., Onoyama, I., Okita, Y., Nakayama, K. & Nakayama, K., 4 1 2011, : : Cancer Science. 102, 4, p. 749-755 7 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Four mood stabilizers commonly induce FEZ1 expression in human astrocytes

Yu, Z., Ono, C., Kim, H. B., Komatsu, H., Tanabe, Y., Sakae, N., Nakayama, K., Matsuoka, H., Sora, I., Bunney, W. E. & Tomita, H., 8 1 2011, : : Bipolar Disorders. 13, 5-6, p. 486-499 14 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases

Honda, H., Matsumoto, M., Shijo, M., Hamasaki, H., Sadashima, S., Suzuki, S. O., Aishima, S., Kai, K., Nakayama, K. I., Sasagasako, N. & Iwaki, T., 10 1 2019, : : Journal of neuropathology and experimental neurology. 78, 10, p. 922-929 8 p.

研究成果: ジャーナルへの寄稿記事

Functional analyses of the activation loop of phototropin2 in Arabidopsis

Inoue, S. I., Matsushita, T., Tomokiyo, Y., Matsumoto, M., Nakayama, K. I., Kinoshita, T. & Shimazaki, K. I., 5 1 2011, : : Plant physiology. 156, 1, p. 117-128 12 p.

研究成果: ジャーナルへの寄稿記事

51 引用 (Scopus)

Genetic reevaluation of the Role of F-Box proteins in cyclin D1 degradation

Kanie, T., Onoyama, I., Matsumoto, A., Yamada, M., Nakatsumi, H., Tateishi, Y., Yamamura, S., Tsunematsu, R., Matsumoto, M. & Nakayama, K. I., 2 1 2012, : : Molecular and cellular biology. 32, 3, p. 590-605 16 p.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2017, : : EMBO Reports. 18, 1, p. 123-137 15 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of cell science. 131, 15

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)