TY - JOUR
T1 - A calcifying fibrous tumor of the stomach difficult to distinguish from gastrointestinal stromal tumor by preoperative endoscopic ultrasonography with a review of the literature
AU - Ishii, Yasushi
AU - Nakata, Kouhei
AU - Ohuchida, Kenoki
AU - Maeyama, Ryo
AU - Mitsumoto, Fujiko
AU - Yamamoto, Hidetaka
AU - Nagai, Eishi
AU - Tanaka, Masao
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014
Y1 - 2014
N2 - We report here a rare case of calcifying fibrous tumor of the stomach. A 35-year-old man had a medical checkup, where upper gastrointestinal endoscopy revealed a protruding submucosal tumor on the anterior wall of the gastric body with a slightly mild erythematous surface. Endoscopic ultrasonography showed a heterogeneous hypoechoic lesion with shadowing, consistent with calcification. Continuity between the tumor and the muscularis propria was suspected. Contrast-enhanced computed tomography showed a gastric tumor with delayed enhancement. Laparoscopic partial gastrectomy was performed. Microscopically, the tumor consisted of spindle-shaped cells with hyalinized fibrocollagenous tissue accompanied by psammomatous calcification and multifocal lymphoplasmacytic infiltrate. Immunohistochemically, the tumor was focally positive for CD34 and negative for c-kit, α-smooth muscle actin, desmin, S-100, and anaplastic lymphoma kinase. The tumor was diagnosed as calcifying fibrous tumor (CFT). CFT is a benign mesenchymal tumor, which is mainly found in soft tissues, and is rare in the stomach.
AB - We report here a rare case of calcifying fibrous tumor of the stomach. A 35-year-old man had a medical checkup, where upper gastrointestinal endoscopy revealed a protruding submucosal tumor on the anterior wall of the gastric body with a slightly mild erythematous surface. Endoscopic ultrasonography showed a heterogeneous hypoechoic lesion with shadowing, consistent with calcification. Continuity between the tumor and the muscularis propria was suspected. Contrast-enhanced computed tomography showed a gastric tumor with delayed enhancement. Laparoscopic partial gastrectomy was performed. Microscopically, the tumor consisted of spindle-shaped cells with hyalinized fibrocollagenous tissue accompanied by psammomatous calcification and multifocal lymphoplasmacytic infiltrate. Immunohistochemically, the tumor was focally positive for CD34 and negative for c-kit, α-smooth muscle actin, desmin, S-100, and anaplastic lymphoma kinase. The tumor was diagnosed as calcifying fibrous tumor (CFT). CFT is a benign mesenchymal tumor, which is mainly found in soft tissues, and is rare in the stomach.
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U2 - 10.5833/jjgs.2013.0061
DO - 10.5833/jjgs.2013.0061
M3 - Article
AN - SCOPUS:84901199037
VL - 47
SP - 268
EP - 274
JO - Japanese Journal of Gastroenterological Surgery
JF - Japanese Journal of Gastroenterological Surgery
SN - 0386-9768
IS - 5
ER -