A case of advanced rectal cancer responding to oral UFT and Leucovorin-based preoperative chemoradiation therapy

Kotaro Shibahara, Takahiro Hirazuka, Manabu Yamamoto, Mizuki Ninomiya, Kojiro Mashino, Kyuzo Fuji, Tetsuo Ikeda, Tadashi Kahno

研究成果: Contribution to journalArticle査読

抄録

We report a case of a 44-year-old male with advanced lower rectal cancer that showed a significant effect after preoperative chemoradiation therapy. Preoperative radiation and chemotherapy included whole pelvis irradiation (30 Gy in total), oral UFT (500 mg/day), and Leucovorin (75 mg/day) was administered daily for 4 weeks. Consequently, the patient underwent a total pelvic exenteration with lymph node dissection (D 3). Histopathological findings showed: invasion to peritoneum(Ai); stage IIIa with n(-); and histological grading, Grade 2. Preoperative chemoradiation therapy appears to be effective for locally advanced lower rectal cancer.

本文言語英語
ページ(範囲)1481-1483
ページ数3
ジャーナルGan to kagaku ryoho. Cancer & chemotherapy
33
10
出版ステータス出版済み - 1 1 2006

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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