抄録
A 52-year-old woman underwent modified radical mastectomy and axillary lymph node resection for right breast cancer (stage II B). Afterwards FEC therapy (5-FU 500 mg/m 2 , epirubicin 75 mg/m 2 , cyclophosphamide 500 mg/m 2 ) X4, docetaxel therapy (60 mg/m 2 ) X 4 and radiation of the illness side collarbone, upper and lower lymph nodes were enforced for adjuvant therapy after the operation. Furthermore, administration of aromatase inhibitor (anastrozole) and trastuzumab was started due to the postoperative pathological diagnosis of hormone receptor-positive and HER2 (score 3+). This became an urgent hospital admission because of the sudden escape power from impaired consciousness due to the articulation disorders and limb weakness when trastuzumab was administered nine times. It was diagnosed by MRI examination and the cerebrospinal fluid cytology as meningeal carcinomatosis of breast cancer, and she died on the 31st recurrence of disease. A serious relapse may be caused in a case of fast-progressing breast cancer like this while being administered trastuzumab as an adjuvant treatment.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 1607-1609 |
| ページ数 | 3 |
| ジャーナル | Japanese Journal of Cancer and Chemotherapy |
| 巻 | 37 |
| 発行部数 | 8 |
| 出版物ステータス | 出版済み - 8 15 2010 |
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All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research
これを引用
A case of breast meningeal carcinomatosis caused by trastuzumab treatment as adjuvant chemotherapy. / Takahashi, Hiroki; Fujii, Teruhiko; Inoue, Yuka; Katsura, Masakazu; Yokoyama, Goro; Namoto, Roka Matsubayashi; Nakayama, Yoshifuku; Momosaki, Seiya; ariyama, hiroshi; Takenaka, Miki; Otsuka, Hiroko; Iwakuma, Nobutaka; Toh, Uhi; Shirouzu, Kazuo.
：: Japanese Journal of Cancer and Chemotherapy, 巻 37, 番号 8, 15.08.2010, p. 1607-1609.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - A case of breast meningeal carcinomatosis caused by trastuzumab treatment as adjuvant chemotherapy
AU - Takahashi, Hiroki
AU - Fujii, Teruhiko
AU - Inoue, Yuka
AU - Katsura, Masakazu
AU - Yokoyama, Goro
AU - Namoto, Roka Matsubayashi
AU - Nakayama, Yoshifuku
AU - Momosaki, Seiya
AU - ariyama, hiroshi
AU - Takenaka, Miki
AU - Otsuka, Hiroko
AU - Iwakuma, Nobutaka
AU - Toh, Uhi
AU - Shirouzu, Kazuo
PY - 2010/8/15
Y1 - 2010/8/15
N2 - A 52-year-old woman underwent modified radical mastectomy and axillary lymph node resection for right breast cancer (stage II B). Afterwards FEC therapy (5-FU 500 mg/m 2 , epirubicin 75 mg/m 2 , cyclophosphamide 500 mg/m 2 ) X4, docetaxel therapy (60 mg/m 2 ) X 4 and radiation of the illness side collarbone, upper and lower lymph nodes were enforced for adjuvant therapy after the operation. Furthermore, administration of aromatase inhibitor (anastrozole) and trastuzumab was started due to the postoperative pathological diagnosis of hormone receptor-positive and HER2 (score 3+). This became an urgent hospital admission because of the sudden escape power from impaired consciousness due to the articulation disorders and limb weakness when trastuzumab was administered nine times. It was diagnosed by MRI examination and the cerebrospinal fluid cytology as meningeal carcinomatosis of breast cancer, and she died on the 31st recurrence of disease. A serious relapse may be caused in a case of fast-progressing breast cancer like this while being administered trastuzumab as an adjuvant treatment.
AB - A 52-year-old woman underwent modified radical mastectomy and axillary lymph node resection for right breast cancer (stage II B). Afterwards FEC therapy (5-FU 500 mg/m 2 , epirubicin 75 mg/m 2 , cyclophosphamide 500 mg/m 2 ) X4, docetaxel therapy (60 mg/m 2 ) X 4 and radiation of the illness side collarbone, upper and lower lymph nodes were enforced for adjuvant therapy after the operation. Furthermore, administration of aromatase inhibitor (anastrozole) and trastuzumab was started due to the postoperative pathological diagnosis of hormone receptor-positive and HER2 (score 3+). This became an urgent hospital admission because of the sudden escape power from impaired consciousness due to the articulation disorders and limb weakness when trastuzumab was administered nine times. It was diagnosed by MRI examination and the cerebrospinal fluid cytology as meningeal carcinomatosis of breast cancer, and she died on the 31st recurrence of disease. A serious relapse may be caused in a case of fast-progressing breast cancer like this while being administered trastuzumab as an adjuvant treatment.
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UR - http://www.scopus.com/inward/citedby.url?scp=79961113112&partnerID=8YFLogxK
M3 - Article
VL - 37
SP - 1607
EP - 1609
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
SN - 0385-0684
IS - 8
ER -